{"id":"https://openalex.org/W2807049535","doi":"https://doi.org/10.5772/intechopen.74071","title":"Pathogenesis of Cholera: Recent Prospectives in Rapid Detection and Prevention of Cholera","display_name":"Pathogenesis of Cholera: Recent Prospectives in Rapid Detection and Prevention of Cholera","publication_year":2018,"publication_date":"2018-05-30","ids":{"openalex":"https://openalex.org/W2807049535","doi":"https://doi.org/10.5772/intechopen.74071","mag":"2807049535"},"language":"en","primary_location":{"id":"doi:10.5772/intechopen.74071","doi":"https://doi.org/10.5772/intechopen.74071","is_oa":true,"landing_page_url":"https://doi.org/10.5772/intechopen.74071","pdf_url":"https://www.intechopen.com/citation-pdf-url/59438","source":{"id":"https://openalex.org/S4306463447","display_name":"InTech eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"ebook platform"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bacterial Pathogenesis and Antibacterial Control","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2888670551","display_name":"Bacterial Pathogenesis and Antibacterial Control"},"type":"book-chapter","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.intechopen.com/citation-pdf-url/59438","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052461154","display_name":"Sharmila Tirumale","orcid":"https://orcid.org/0000-0002-5739-5061","observed_orcids":["https://orcid.org/0000-0002-5739-5061","https://orcid.org/0000-0001-8884-9639"]},"institutions":[{"id":"https://openalex.org/I53465836","display_name":"Bangalore University","ror":"https://ror.org/050j2vm64","country_code":"IN","type":"education","lineage":["https://openalex.org/I53465836"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Tirumale Sharmila","raw_affiliation_strings":["Department of Microbiology and Biotechnology, Jnana Bharathi Campus, Bangalore University, Bangalore, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Biotechnology, Jnana Bharathi Campus, Bangalore University, Bangalore, India","institution_ids":["https://openalex.org/I53465836"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043056711","display_name":"Tessy Anu Thomas","orcid":"https://orcid.org/0000-0002-1388-4525","observed_orcids":["https://orcid.org/0000-0002-1388-4525"]},"institutions":[{"id":"https://openalex.org/I53465836","display_name":"Bangalore University","ror":"https://ror.org/050j2vm64","country_code":"IN","type":"education","lineage":["https://openalex.org/I53465836"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Tessy Anu Thomas","raw_affiliation_strings":["Department of Microbiology and Biotechnology, Jnana Bharathi Campus, Bangalore University, Bangalore, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Biotechnology, Jnana Bharathi Campus, Bangalore University, Bangalore, India","institution_ids":["https://openalex.org/I53465836"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5052461154"],"corresponding_institution_ids":["https://openalex.org/I53465836"],"apc_list":null,"apc_paid":null,"fwci":2.8286,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.88425047,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11684","display_name":"Vibrio bacteria research studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11684","display_name":"Vibrio bacteria research studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10486","display_name":"Salmonella and Campylobacter epidemiology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cholera","display_name":"cholera","score":0.9769999980926514},{"id":"https://openalex.org/keywords/vibrio-cholerae","display_name":"Vibrio cholerae","score":0.9980000257492065},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.7559999823570251},{"id":"https://openalex.org/keywords/cholera-toxin","display_name":"cholera toxin","score":0.972000002861023},{"id":"https://openalex.org/keywords/o139-serogroup","display_name":"O139 serogroup","score":0.8040000200271606},{"id":"https://openalex.org/keywords/drug-resistant-strains","display_name":"drug-resistant strains","score":0.5649999976158142},{"id":"https://openalex.org/keywords/cholera-vaccine","display_name":"cholera vaccine","score":0.5590000152587891},{"id":"https://openalex.org/keywords/rapid-detection","display_name":"rapid detection","score":0.5730000138282776},{"id":"https://openalex.org/keywords/serotyping","display_name":"serotyping","score":0.8550000190734863},{"id":"https://openalex.org/keywords/biotyping","display_name":"biotyping","score":0.9449999928474426},{"id":"https://openalex.org/keywords/hypovolemic-shock","display_name":"hypovolemic shock","score":0.7379999756813049},{"id":"https://openalex.org/keywords/waterborne-diseases","display_name":"waterborne diseases","score":0.4740000069141388}],"concepts":[{"id":"https://openalex.org/C2780722889","wikidata":"https://www.wikidata.org/wiki/Q12090","display_name":"Cholera","level":2,"score":0.9265727996826172},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.5601530075073242},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5175156593322754},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5073463320732117},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.27767494320869446}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.5772/intechopen.74071","doi":"https://doi.org/10.5772/intechopen.74071","is_oa":true,"landing_page_url":"https://doi.org/10.5772/intechopen.74071","pdf_url":"https://www.intechopen.com/citation-pdf-url/59438","source":{"id":"https://openalex.org/S4306463447","display_name":"InTech eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"ebook platform"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bacterial Pathogenesis and Antibacterial Control","raw_type":"book-chapter"},{"id":"pmh:oai:biblioboard.com:92c23642-dd25-4268-9926-fe4a7fbebbd5","doi":null,"is_oa":true,"landing_page_url":"https://openresearchlibrary.org/viewer/92c23642-dd25-4268-9926-fe4a7fbebbd5","pdf_url":null,"source":{"id":"https://openalex.org/S4306401131","display_name":"BiblioBoard Library Catalog (Open Research Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"MODID-6d55e02e354:IntechOpen","raw_type":"CHAPTER"},{"id":"pmh:oai:intechopen.com:59438","doi":null,"is_oa":true,"landing_page_url":"http://www.intechopen.com/articles/show/title/pathogenesis-of-cholera-recent-prospectives-in-rapid-detection-and-prevention-of-cholera","pdf_url":null,"source":{"id":"https://openalex.org/S4306401291","display_name":"Contact-less Assessment of In-vivo Body Signals Using Microwave Doppler Radar (InTech)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210154139","host_organization_name":"Intech (Slovakia)","host_organization_lineage":["https://openalex.org/I4210154139"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.intechopen.com/download/pdf/pdfs_id/59438","raw_type":"07"}],"best_oa_location":{"id":"doi:10.5772/intechopen.74071","doi":"https://doi.org/10.5772/intechopen.74071","is_oa":true,"landing_page_url":"https://doi.org/10.5772/intechopen.74071","pdf_url":"https://www.intechopen.com/citation-pdf-url/59438","source":{"id":"https://openalex.org/S4306463447","display_name":"InTech eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"ebook platform"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bacterial Pathogenesis and Antibacterial Control","raw_type":"book-chapter"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2807049535.pdf","grobid_xml":"https://content.openalex.org/works/W2807049535.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W14738797","https://openalex.org/W1505033636","https://openalex.org/W1607939748","https://openalex.org/W1966116088","https://openalex.org/W1966148737","https://openalex.org/W1976169651","https://openalex.org/W2005937957","https://openalex.org/W2029404175","https://openalex.org/W2058080689","https://openalex.org/W2060779079","https://openalex.org/W2110036287","https://openalex.org/W2113523267","https://openalex.org/W2117893430","https://openalex.org/W2118459919","https://openalex.org/W2132341147","https://openalex.org/W2164485511","https://openalex.org/W2259670649","https://openalex.org/W2339629547","https://openalex.org/W2607598315"],"related_works":["https://openalex.org/W2171772727","https://openalex.org/W4230860716","https://openalex.org/W7096848852","https://openalex.org/W4248075272","https://openalex.org/W4361974858","https://openalex.org/W4396847792","https://openalex.org/W1585473065","https://openalex.org/W2257992441","https://openalex.org/W1565061204","https://openalex.org/W70856714"],"abstract_inverted_index":{"Cholera,":[0],"also":[1,51],"known":[2,182],"as":[3,183,302,304],"\u201cblue":[4],"death\u201d":[5],"is":[6,59,108,258,294,307],"a":[7,60,127,215,264,275,290],"potentially":[8],"epidemic":[9,324],"and":[10,24,29,94,132,160,202,210,234,238,280,320,333,337,351,377],"life-threatening":[11],"secretory":[12],"diarrhea":[13],"characterized":[14],"by":[15,22,195,221,344],"numerous":[16],"voluminous":[17],"watery":[18],"stools,":[19],"often":[20],"accompanied":[21],"vomiting":[23],"resulting":[25],"in":[26,129,217,260,313,339,349,352,371],"hypovolemic":[27],"shock":[28],"acidosis.":[30],"The":[31,99,120,158,171,212,236,252,297,318],"causative":[32],"agent":[33],"of":[34,42,70,78,86,101,106,112,123,148,153,156,162,169,188,198,214,225,240,254,256,277,284,299,309,322,331,347,359,363],"this":[35,261,323],"water-borne":[36],"disease":[37,164,181,204,325],"belongs":[38],"to":[39,116,145,208,245,271,341,368,373],"certain":[40],"members":[41,77],"the":[43,67,79,109,136,146,154,163,167,178,189,199,203,230,241,282,300,310,314,328,360,374,382],"species":[44,80],"Vibrio":[45,107,332],"cholerae":[46,58,176,197,227],"(V.":[47],"cholerae)":[48],"which":[49,65,288,379],"can":[50],"cause":[52,83,111],"mild":[53],"or":[54],"unapparent":[55],"infections.":[56],"V.":[57,175,196,226],"facultative":[61],"anaerobic,":[62],"Gram-negative":[63],"bacilli,":[64],"possess":[66],"characteristic":[68],"feature":[69],"darting":[71],"motility":[72],"under":[73,295],"wet-mound":[74],"preparations.":[75],"Other":[76],"may":[81],"occasionally":[82],"isolated":[84],"outbreaks":[85,114,376],"milder":[87],"diarrhea,":[88],"whereas":[89],"others\u2014the":[90],"vast":[91],"majority\u2014are":[92],"free-living":[93],"not":[95],"associated":[96],"with":[97,335,366],"disease.":[98],"emergence":[100,213],"new,":[102],"virulent,":[103],"drug-resistant":[104],"strains":[105],"main":[110,311],"protracted":[113],"leading":[115],"high":[117],"fatality":[118,161],"rates.":[119],"subsequent":[121],"loss":[122],"fluid":[124],"volume":[125],"causes":[126],"drop":[128],"blood":[130],"pressure":[131],"circulatory":[133],"shock.":[134],"If":[135],"patient":[137],"remains":[138],"untreated,":[139],"they":[140],"become":[141],"progressively":[142],"weaker,":[143],"sometimes":[144],"point":[147],"death,":[149],"within":[150],"12\u201324":[151],"h":[152],"onset":[155],"symptoms.":[157],"severity":[159],"depend":[165],"on":[166],"strain":[168],"Vibrio.":[170],"cholera":[172,184,192,369],"toxin-producing":[173],"(CT-producing)":[174],"manifests":[177],"most":[179,187],"fatal":[180],"gravis.":[185],"Throughout":[186],"twentieth":[190],"century,":[191],"was":[193,205,219],"caused":[194,220],"O1":[200],"serogroup,":[201],"largely":[206],"confined":[207],"Asia":[209],"Africa.":[211],"pandemic":[216],"1992":[218],"an":[222,246,285],"unknown":[223],"serogroup":[224],"(O139)":[228],"wherein":[229],"targets":[231],"were":[232],"India":[233],"Bangladesh.":[235],"pathogenesis":[237],"virulence":[239],"bacteria":[242,301],"are":[243],"due":[244],"enterotoxin":[247],"it":[248],"produces\u2014cholera":[249],"toxin":[250,305,342],"(CT).":[251],"mechanism":[253],"action":[255],"CT":[257],"discussed":[259],"chapter":[262,355],"at":[263],"later":[265],"stage.":[266],"Attempts":[267],"have":[268],"been":[269],"made":[270],"produce":[272],"vaccines":[273],"through":[274],"number":[276],"trial-and-error":[278],"methods,":[279],"still":[281],"possibility":[283],"effective":[286],"vaccine":[287],"gives":[289],"good":[291],"prophylactic":[292],"measure":[293],"consideration.":[296],"identification":[298,319,330],"well":[303],"detection":[306,343],"one":[308],"elements":[312],"clinical":[315,364],"microbiology":[316,365],"field.":[317],"confirmation":[321],"commend":[326],"from":[327],"morphological":[329],"end":[334],"serotyping":[336],"biotyping":[338],"addition":[340,372],"various":[345],"means":[346],"assays\u2014both":[348],"vitro":[350],"vivo.":[353],"This":[354],"will":[356],"cover":[357],"all":[358],"mentioned":[361],"areas":[362],"respect":[367],"infection":[370],"recent":[375],"epidemics":[378],"occurred":[380],"across":[381],"globe.":[383]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2018-06-13T00:00:00"}