{"id":"https://openalex.org/W2806651973","doi":"https://doi.org/10.15578/squalen.319","title":"Antioxidant and Ace Inhibitor Potential of Stripe Trevally Fish (Selaroides leptolepis) Hydrolysate","display_name":"Antioxidant and Ace Inhibitor Potential of Stripe Trevally Fish (Selaroides leptolepis) Hydrolysate","publication_year":2018,"publication_date":"2018-05-31","ids":{"openalex":"https://openalex.org/W2806651973","doi":"https://doi.org/10.15578/squalen.319","mag":"2806651973"},"language":"en","primary_location":{"id":"doi:10.15578/squalen.319","doi":"https://doi.org/10.15578/squalen.319","is_oa":true,"landing_page_url":"https://doi.org/10.15578/squalen.319","pdf_url":"https://squalen.labdata.id/index.php/squalen/article/download/319/pdf","source":{"id":"https://openalex.org/S2764410179","display_name":"SQUALEN Bulletin of Marine and Fisheries Postharvest and Biotechnology","issn_l":"2089-5690","issn":["2089-5690","2406-9272"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315139","host_organization_name":"Pusat Penelitian dan Pengembangan Daya Saing Produk dan Bioteknologi Kelautan dan Perikanan","host_organization_lineage":["https://openalex.org/P4310315139"],"host_organization_lineage_names":["Pusat Penelitian dan Pengembangan Daya Saing Produk dan Bioteknologi Kelautan dan Perikanan"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://squalen.labdata.id/index.php/squalen/article/download/319/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042918545","display_name":"Reinal Putalan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I21881038","display_name":"IPB University","ror":"https://ror.org/05smgpd89","country_code":"ID","type":"education","lineage":["https://openalex.org/I21881038"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Reinal Putalan","raw_affiliation_strings":["Institut Pertanian Bogor"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Pertanian Bogor","institution_ids":["https://openalex.org/I21881038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082817798","display_name":"Ifah Munifah","orcid":"https://orcid.org/0000-0001-7143-1092","observed_orcids":["https://orcid.org/0000-0001-7143-1092"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ifah Munifah","raw_affiliation_strings":["Research and Development Center for Marine and Fisheries Product Processing and Biotechnology Jl. KS. Tubun Petamburan VI, Jakarta 10260 Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research and Development Center for Marine and Fisheries Product Processing and Biotechnology Jl. KS. Tubun Petamburan VI, Jakarta 10260 Indonesia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061626550","display_name":"\u202aTati Nurhayati","orcid":"https://orcid.org/0000-0003-2941-4576","observed_orcids":["https://orcid.org/0000-0003-2941-4576"]},"institutions":[{"id":"https://openalex.org/I21881038","display_name":"IPB University","ror":"https://ror.org/05smgpd89","country_code":"ID","type":"education","lineage":["https://openalex.org/I21881038"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Tati Nurhayati","raw_affiliation_strings":["Department of Aquatic Product Technology, Bogor Agricultural University, Jalan Lingkar Akademik Kampus IPB Dramaga, Bogor 16680, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Aquatic Product Technology, Bogor Agricultural University, Jalan Lingkar Akademik Kampus IPB Dramaga, Bogor 16680, Indonesia","institution_ids":["https://openalex.org/I21881038"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064094082","display_name":"Ekowati Chasanah","orcid":"https://orcid.org/0000-0002-5974-0690","observed_orcids":["https://orcid.org/0000-0002-5974-0690"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Ekowati Chasanah","raw_affiliation_strings":["Research and Development Center for Marine and Fisheries Product Processing and Biotechnology Jl. KS. Tubun Petamburan VI, Jakarta 10260 Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research and Development Center for Marine and Fisheries Product Processing and Biotechnology Jl. KS. Tubun Petamburan VI, Jakarta 10260 Indonesia","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5064094082"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5643,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.65701223,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"13","issue":"1","first_page":"17","last_page":"17"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11561","display_name":"Protein Hydrolysis and Bioactive Peptides","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11561","display_name":"Protein Hydrolysis and Bioactive Peptides","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14127","display_name":"Food Nutrient Composition and Product Development","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12505","display_name":"Peptidase Inhibition and Analysis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fish-protein-hydrolysate","display_name":"fish protein hydrolysate","score":0.8930000066757202},{"id":"https://openalex.org/keywords/selaroides-leptolepis","display_name":"Selaroides leptolepis","score":1.0},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.8849999904632568},{"id":"https://openalex.org/keywords/angiotensin-converting-enzyme-inhibition","display_name":"angiotensin-converting enzyme inhibition","score":0.9169999957084656},{"id":"https://openalex.org/keywords/antihypertensive-peptides","display_name":"antihypertensive peptides","score":0.9160000085830688},{"id":"https://openalex.org/keywords/bacillus-licheniformis-protease","display_name":"Bacillus licheniformis protease","score":0.9240000247955322},{"id":"https://openalex.org/keywords/enzymatic-hydrolysis","display_name":"enzymatic hydrolysis","score":0.9909999966621399},{"id":"https://openalex.org/keywords/ultrafiltration-fractionation","display_name":"ultrafiltration fractionation","score":0.9200000166893005},{"id":"https://openalex.org/keywords/molecular-weight-fractionation","display_name":"molecular weight fractionation","score":0.6359999775886536},{"id":"https://openalex.org/keywords/degree-of-hydrolysis","display_name":"degree of hydrolysis","score":0.828000009059906},{"id":"https://openalex.org/keywords/functional-food-ingredients","display_name":"functional food ingredients","score":0.7419999837875366}],"concepts":[{"id":"https://openalex.org/C28800991","wikidata":"https://www.wikidata.org/wiki/Q15634405","display_name":"Hydrolysate","level":3,"score":0.8946505188941956},{"id":"https://openalex.org/C50817676","wikidata":"https://www.wikidata.org/wiki/Q7880534","display_name":"Ultrafiltration (renal)","level":2,"score":0.7839471101760864},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7566546201705933},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.7096779942512512},{"id":"https://openalex.org/C94412978","wikidata":"https://www.wikidata.org/wiki/Q103135","display_name":"Hydrolysis","level":2,"score":0.6852568984031677},{"id":"https://openalex.org/C53270655","wikidata":"https://www.wikidata.org/wiki/Q5381536","display_name":"Enzymatic hydrolysis","level":3,"score":0.5359412431716919},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.4967091679573059},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.45246458053588867},{"id":"https://openalex.org/C2777752497","wikidata":"https://www.wikidata.org/wiki/Q286779","display_name":"IC50","level":3,"score":0.4105721116065979},{"id":"https://openalex.org/C97428945","wikidata":"https://www.wikidata.org/wiki/Q15305109","display_name":"Fractionation","level":2,"score":0.41048765182495117},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3327510952949524},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.050307899713516235}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.15578/squalen.319","doi":"https://doi.org/10.15578/squalen.319","is_oa":true,"landing_page_url":"https://doi.org/10.15578/squalen.319","pdf_url":"https://squalen.labdata.id/index.php/squalen/article/download/319/pdf","source":{"id":"https://openalex.org/S2764410179","display_name":"SQUALEN Bulletin of Marine and Fisheries Postharvest and Biotechnology","issn_l":"2089-5690","issn":["2089-5690","2406-9272"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315139","host_organization_name":"Pusat Penelitian dan Pengembangan Daya Saing Produk dan Bioteknologi Kelautan dan Perikanan","host_organization_lineage":["https://openalex.org/P4310315139"],"host_organization_lineage_names":["Pusat Penelitian dan Pengembangan Daya Saing Produk dan Bioteknologi Kelautan dan Perikanan"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology","raw_type":"journal-article"},{"id":"doi:10.15578/squalen.v13i1.319","doi":"https://doi.org/10.15578/squalen.v13i1.319","is_oa":true,"landing_page_url":"https://doi.org/10.15578/squalen.v13i1.319","pdf_url":"https://www.bbp4b.litbang.kkp.go.id/squalen-bulletin/index.php/squalen/article/download/319/pdf","source":{"id":"https://openalex.org/S2764410179","display_name":"SQUALEN Bulletin of Marine and Fisheries Postharvest and Biotechnology","issn_l":"2089-5690","issn":["2089-5690","2406-9272"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315139","host_organization_name":"Pusat Penelitian dan Pengembangan Daya Saing Produk dan Bioteknologi Kelautan dan Perikanan","host_organization_lineage":["https://openalex.org/P4310315139"],"host_organization_lineage_names":["Pusat Penelitian dan Pengembangan Daya Saing Produk dan Bioteknologi Kelautan dan Perikanan"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:327f6ab9098e48bcb8a42f3720aad679","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/327f6ab9098e48bcb8a42f3720aad679","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Squalen, Vol 13, Iss 1, Pp 17-22 (2018)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.15578/squalen.319","doi":"https://doi.org/10.15578/squalen.319","is_oa":true,"landing_page_url":"https://doi.org/10.15578/squalen.319","pdf_url":"https://squalen.labdata.id/index.php/squalen/article/download/319/pdf","source":{"id":"https://openalex.org/S2764410179","display_name":"SQUALEN Bulletin of Marine and Fisheries Postharvest and Biotechnology","issn_l":"2089-5690","issn":["2089-5690","2406-9272"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315139","host_organization_name":"Pusat Penelitian dan Pengembangan Daya Saing Produk dan Bioteknologi Kelautan dan Perikanan","host_organization_lineage":["https://openalex.org/P4310315139"],"host_organization_lineage_names":["Pusat Penelitian dan Pengembangan Daya Saing Produk dan Bioteknologi Kelautan dan Perikanan"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.428600013256073,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2806651973.pdf","grobid_xml":"https://content.openalex.org/works/W2806651973.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W1156324490","https://openalex.org/W1542992498","https://openalex.org/W1828118566","https://openalex.org/W1909437036","https://openalex.org/W1964492485","https://openalex.org/W1964888724","https://openalex.org/W1975630793","https://openalex.org/W1975754383","https://openalex.org/W1990355893","https://openalex.org/W1992397982","https://openalex.org/W1998836648","https://openalex.org/W2003694301","https://openalex.org/W2012275144","https://openalex.org/W2024580100","https://openalex.org/W2025482327","https://openalex.org/W2026564439","https://openalex.org/W2043031857","https://openalex.org/W2046575388","https://openalex.org/W2061805928","https://openalex.org/W2083671868","https://openalex.org/W2106837407","https://openalex.org/W2115896899","https://openalex.org/W2121223201","https://openalex.org/W2158517899","https://openalex.org/W2165201727","https://openalex.org/W2177971586","https://openalex.org/W2366472627","https://openalex.org/W2473717350","https://openalex.org/W2521724556","https://openalex.org/W2524903672","https://openalex.org/W4232503235"],"related_works":["https://openalex.org/W4386325934","https://openalex.org/W6931212991","https://openalex.org/W775520658","https://openalex.org/W1967294324","https://openalex.org/W1986265287","https://openalex.org/W3022099271","https://openalex.org/W2075907898","https://openalex.org/W2762702810","https://openalex.org/W2021840805","https://openalex.org/W2080579762"],"abstract_inverted_index":{"This":[0],"study":[1],"aimed":[2],"to":[3,173],"investigate":[4],"the":[5,136,139,145,157,159,207],"potency":[6],"of":[7,12,38,65,96,106,112,121,127,132,156,194,203,211],"fish":[8,15,214],"protein":[9,74,104,147,209],"hydrolysates":[10],"(FPH)":[11],"stripe":[13,212],"trevally":[14,213],"(Selaroides":[16],"leptolepis)":[17],"as":[18,176,224,229],"antioxidant":[19,78,118,161,187],"and":[20,40,45,49,68,80,109,124,149,162,192],"ACE":[21,125,163,195],"inhibitor.":[22],"The":[23,52,71,87,152,166,185],"FPH":[24,53,91,116],"was":[25,54,178,189,197,222],"produced":[26,32,215],"through":[27],"enzymatically":[28],"hydrolysis":[29,72,94,102,218],"using":[30,56,219],"protease":[31,221],"by":[33,216],"Bacillus":[34],"licheniformis,":[35],"a":[36,201,225],"collection":[37],"Research":[39],"Development":[41],"Center":[42],"for":[43],"Marine":[44],"Fisheries":[46],"Product":[47],"Processing":[48],"Biotechnology":[50],"(RDCMFPPB).":[51],"fractionated":[55],"ultrafiltration":[57,137],"membranes":[58],"with":[59,103],"molecular":[60,141,154],"weight":[61,155],"cut":[62,142],"off":[63,143],"(MWCO)":[64],"10,":[66],"5":[67],"3":[69],"kDa.":[70,184],"degree,":[73],"content,":[75,77],"peptide":[76,110,150],"activity":[79,119,188],"Angiotensin-converting":[81],"enzyme":[82],"(ACE)":[83],"inhibitor":[84,126,164,196],"were":[85],"observed.":[86],"result":[88],"showed":[89,117],"that":[90,169],"had":[92],"maximum":[93],"degree":[95],"63.91%":[97],"reached":[98],"after":[99],"6":[100],"hours":[101],"content":[105,111,148],"27.43":[107],"mg/mL":[108],"223.32":[113],"mg/mL.":[114,134],"That":[115],"(IC50)":[120],"1941.06":[122],"ppm":[123,191],"87.82%":[128],"at":[129],"test":[130],"concentration":[131,202],"10":[133,204],"In":[135],"step,":[138],"higher":[140,146],"used,":[144],"content.":[151],"lower":[153],"hydrolysate,":[158],"better":[160],"activity.":[165],"best":[167],"fractionation":[168],"produce":[170],"potential":[171,223],"product":[172],"be":[174],"used":[175],"anti-hypertension":[177],"in":[179],"mixture":[180],"peptides":[181],"between":[182],"3-5":[183],"IC50":[186],"1336.96":[190],"percentage":[193],"97.15%":[198],"%":[199],"(with":[200],"mg/mL).":[205],"From":[206],"results,":[208],"hydrolysate":[210],"enzymatic":[217],"local":[220],"functional":[226],"ingredient,":[227],"particularly":[228],"antihypertensive":[230],"agent.":[231]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-06-13T00:00:00"}