{"id":"https://openalex.org/W2806581632","doi":"https://doi.org/10.1186/s12989-018-0261-5","title":"Cerium dioxide nanoparticles exacerbate house dust mite induced type II airway inflammation","display_name":"Cerium dioxide nanoparticles exacerbate house dust mite induced type II airway inflammation","publication_year":2018,"publication_date":"2018-05-23","ids":{"openalex":"https://openalex.org/W2806581632","doi":"https://doi.org/10.1186/s12989-018-0261-5","mag":"2806581632","pmid":"https://pubmed.ncbi.nlm.nih.gov/29792201","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5966909"},"language":"en","primary_location":{"id":"doi:10.1186/s12989-018-0261-5","doi":"https://doi.org/10.1186/s12989-018-0261-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12989-018-0261-5","pdf_url":"https://particleandfibretoxicology.biomedcentral.com/counter/pdf/10.1186/s12989-018-0261-5","source":{"id":"https://openalex.org/S189275214","display_name":"Particle and Fibre Toxicology","issn_l":"1743-8977","issn":["1743-8977"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Particle and Fibre Toxicology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://particleandfibretoxicology.biomedcentral.com/counter/pdf/10.1186/s12989-018-0261-5","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038646534","display_name":"Kirsty Meldrum","orcid":"https://orcid.org/0000-0002-2658-6850","observed_orcids":["https://orcid.org/0000-0002-2658-6850"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I348769827","display_name":"Public Health England","ror":"https://ror.org/00vbvha87","country_code":"GB","type":"government","lineage":["https://openalex.org/I1311074006","https://openalex.org/I348769827"]},{"id":"https://openalex.org/I34931013","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08","country_code":"GB","type":"government","lineage":["https://openalex.org/I34931013"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kirsty Meldrum","raw_affiliation_strings":["Lung Cell Biology, Airways Disease, National Heart & Lung Institute, Imperial College London, London, UK","The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK","Toxicology Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Chilton, OX110RQ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lung Cell Biology, Airways Disease, National Heart & Lung Institute, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK","institution_ids":["https://openalex.org/I183935753","https://openalex.org/I348769827","https://openalex.org/I34931013","https://openalex.org/I47508984"]},{"raw_affiliation_string":"Toxicology Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Chilton, OX110RQ, UK","institution_ids":["https://openalex.org/I348769827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102829584","display_name":"Sarah Robertson","orcid":"https://orcid.org/0000-0001-9907-9289","observed_orcids":["https://orcid.org/0000-0001-9907-9289"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I348769827","display_name":"Public Health England","ror":"https://ror.org/00vbvha87","country_code":"GB","type":"government","lineage":["https://openalex.org/I1311074006","https://openalex.org/I348769827"]},{"id":"https://openalex.org/I34931013","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08","country_code":"GB","type":"government","lineage":["https://openalex.org/I34931013"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sarah B. Robertson","raw_affiliation_strings":["Environmental Hazards and Emergencies Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Chilton, Harwell Campus, Chilton, OX110RQ, UK","The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Environmental Hazards and Emergencies Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Chilton, Harwell Campus, Chilton, OX110RQ, UK","institution_ids":["https://openalex.org/I348769827"]},{"raw_affiliation_string":"The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK","institution_ids":["https://openalex.org/I183935753","https://openalex.org/I348769827","https://openalex.org/I34931013","https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083244382","display_name":"Isabella R\u00f6mer","orcid":"https://orcid.org/0000-0003-3556-970X","observed_orcids":["https://orcid.org/0000-0003-3556-970X"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I348769827","display_name":"Public Health England","ror":"https://ror.org/00vbvha87","country_code":"GB","type":"government","lineage":["https://openalex.org/I1311074006","https://openalex.org/I348769827"]},{"id":"https://openalex.org/I34931013","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08","country_code":"GB","type":"government","lineage":["https://openalex.org/I34931013"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Isabella R\u00f6mer","raw_affiliation_strings":["The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK","Toxicology Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Chilton, OX110RQ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK","institution_ids":["https://openalex.org/I183935753","https://openalex.org/I348769827","https://openalex.org/I34931013","https://openalex.org/I47508984"]},{"raw_affiliation_string":"Toxicology Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Chilton, OX110RQ, UK","institution_ids":["https://openalex.org/I348769827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011148699","display_name":"Tim H. Marczylo","orcid":"https://orcid.org/0000-0001-9744-473X","observed_orcids":["https://orcid.org/0000-0001-9744-473X"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I348769827","display_name":"Public Health England","ror":"https://ror.org/00vbvha87","country_code":"GB","type":"government","lineage":["https://openalex.org/I1311074006","https://openalex.org/I348769827"]},{"id":"https://openalex.org/I34931013","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08","country_code":"GB","type":"government","lineage":["https://openalex.org/I34931013"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tim Marczylo","raw_affiliation_strings":["The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK","Toxicology Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Chilton, OX110RQ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK","institution_ids":["https://openalex.org/I183935753","https://openalex.org/I348769827","https://openalex.org/I34931013","https://openalex.org/I47508984"]},{"raw_affiliation_string":"Toxicology Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Chilton, OX110RQ, UK","institution_ids":["https://openalex.org/I348769827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068537221","display_name":"Lareb S. N. Dean","orcid":"https://orcid.org/0000-0002-8703-9236","observed_orcids":["https://orcid.org/0000-0002-8703-9236"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I348769827","display_name":"Public Health England","ror":"https://ror.org/00vbvha87","country_code":"GB","type":"government","lineage":["https://openalex.org/I1311074006","https://openalex.org/I348769827"]},{"id":"https://openalex.org/I34931013","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08","country_code":"GB","type":"government","lineage":["https://openalex.org/I34931013"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Lareb S. N. Dean","raw_affiliation_strings":["Lung Cell Biology, Airways Disease, National Heart & Lung Institute, Imperial College London, London, UK","The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lung Cell Biology, Airways Disease, National Heart & Lung Institute, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK","institution_ids":["https://openalex.org/I183935753","https://openalex.org/I348769827","https://openalex.org/I34931013","https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111063501","display_name":"Andrew V. Rogers","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew Rogers","raw_affiliation_strings":["Lung Cell Biology, Airways Disease, National Heart & Lung Institute, Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lung Cell Biology, Airways Disease, National Heart & Lung Institute, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078090457","display_name":"Timothy W. Gant","orcid":"https://orcid.org/0000-0001-9057-4937","observed_orcids":["https://orcid.org/0000-0001-9057-4937"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I348769827","display_name":"Public Health England","ror":"https://ror.org/00vbvha87","country_code":"GB","type":"government","lineage":["https://openalex.org/I1311074006","https://openalex.org/I348769827"]},{"id":"https://openalex.org/I34931013","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08","country_code":"GB","type":"government","lineage":["https://openalex.org/I34931013"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Timothy W. Gant","raw_affiliation_strings":["The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK","Toxicology Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Chilton, OX110RQ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK","institution_ids":["https://openalex.org/I183935753","https://openalex.org/I348769827","https://openalex.org/I34931013","https://openalex.org/I47508984"]},{"raw_affiliation_string":"Toxicology Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Chilton, OX110RQ, UK","institution_ids":["https://openalex.org/I348769827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088118286","display_name":"Rachel Ruckdeschel Smith","orcid":"https://orcid.org/0000-0002-9784-3586","observed_orcids":["https://orcid.org/0000-0002-9784-3586"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I348769827","display_name":"Public Health England","ror":"https://ror.org/00vbvha87","country_code":"GB","type":"government","lineage":["https://openalex.org/I1311074006","https://openalex.org/I348769827"]},{"id":"https://openalex.org/I34931013","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08","country_code":"GB","type":"government","lineage":["https://openalex.org/I34931013"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Rachel Smith","raw_affiliation_strings":["The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK","Toxicology Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Chilton, OX110RQ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK","institution_ids":["https://openalex.org/I183935753","https://openalex.org/I348769827","https://openalex.org/I34931013","https://openalex.org/I47508984"]},{"raw_affiliation_string":"Toxicology Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Chilton, OX110RQ, UK","institution_ids":["https://openalex.org/I348769827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109348492","display_name":"Terry Tetley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I348769827","display_name":"Public Health England","ror":"https://ror.org/00vbvha87","country_code":"GB","type":"government","lineage":["https://openalex.org/I1311074006","https://openalex.org/I348769827"]},{"id":"https://openalex.org/I34931013","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08","country_code":"GB","type":"government","lineage":["https://openalex.org/I34931013"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Terry D. Tetley","raw_affiliation_strings":["Lung Cell Biology, Airways Disease, National Heart & Lung Institute, Imperial College London, London, UK","The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lung Cell Biology, Airways Disease, National Heart & Lung Institute, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK","institution_ids":["https://openalex.org/I183935753","https://openalex.org/I348769827","https://openalex.org/I34931013","https://openalex.org/I47508984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027323377","display_name":"Martin Oliver Leonard","orcid":"https://orcid.org/0000-0003-3042-7833","observed_orcids":["https://orcid.org/0000-0003-3042-7833"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I348769827","display_name":"Public Health England","ror":"https://ror.org/00vbvha87","country_code":"GB","type":"government","lineage":["https://openalex.org/I1311074006","https://openalex.org/I348769827"]},{"id":"https://openalex.org/I34931013","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08","country_code":"GB","type":"government","lineage":["https://openalex.org/I34931013"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Martin O. Leonard","raw_affiliation_strings":["The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK. Martin.Leonard@phe.gov.uk","Toxicology Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Chilton, OX110RQ, UK. Martin.Leonard@phe.gov.uk","The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK. Martin.Leonard@phe.gov.uk","institution_ids":["https://openalex.org/I183935753","https://openalex.org/I348769827","https://openalex.org/I34931013","https://openalex.org/I47508984"]},{"raw_affiliation_string":"Toxicology Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Chilton, OX110RQ, UK. Martin.Leonard@phe.gov.uk","institution_ids":["https://openalex.org/I348769827"]},{"raw_affiliation_string":"The National Institute for Health Research Health Protection Research Unit (NIHR HPRU), Health Impact of Environmental Hazards at King's College London in partnership with Public Health England (PHE) in collaboration with Imperial College London, London, UK","institution_ids":["https://openalex.org/I183935753","https://openalex.org/I348769827","https://openalex.org/I34931013","https://openalex.org/I47508984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5027323377"],"corresponding_institution_ids":["https://openalex.org/I183935753","https://openalex.org/I348769827","https://openalex.org/I34931013","https://openalex.org/I47508984"],"apc_list":{"value":4090,"currency":"USD","value_usd":4090},"apc_paid":{"value":4090,"currency":"USD","value_usd":4090},"fwci":3.2462,"has_fulltext":true,"cited_by_count":34,"citation_normalized_percentile":{"value":0.92644318,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"15","issue":"1","first_page":"24","last_page":"24"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9643999934196472,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9643999934196472,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12208","display_name":"Occupational exposure and asthma","score":0.014000000432133675,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10190","display_name":"Air Quality and Health Impacts","score":0.004800000227987766,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cerium-oxide-nanoparticles","display_name":"cerium oxide nanoparticles","score":0.9980000257492065},{"id":"https://openalex.org/keywords/house-dust-mites","display_name":"house dust mites","score":0.9020000100135803},{"id":"https://openalex.org/keywords/asthma","display_name":"asthma","score":0.6200000047683716},{"id":"https://openalex.org/keywords/eosinophils","display_name":"eosinophils","score":0.7300000190734863},{"id":"https://openalex.org/keywords/mast-cells","display_name":"mast cells","score":0.9290000200271606},{"id":"https://openalex.org/keywords/goblet-cell-metaplasia","display_name":"goblet cell metaplasia","score":0.8230000138282776},{"id":"https://openalex.org/keywords/airway-hyperresponsiveness","display_name":"airway hyperresponsiveness","score":0.7720000147819519},{"id":"https://openalex.org/keywords/airway-remodeling","display_name":"airway remodeling","score":0.9860000014305115},{"id":"https://openalex.org/keywords/clca1","display_name":"CLCA1","score":0.7900000214576721},{"id":"https://openalex.org/keywords/slc26a4","display_name":"SLC26A4","score":0.9990000128746033},{"id":"https://openalex.org/keywords/bronchial-epithelial-cells","display_name":"bronchial epithelial cells","score":0.7850000262260437},{"id":"https://openalex.org/keywords/neutrophils","display_name":"neutrophils","score":0.7599999904632568},{"id":"https://openalex.org/keywords/type-i-interferon","display_name":"type I interferon","score":0.8659999966621399},{"id":"https://openalex.org/keywords/irf3","display_name":"IRF3","score":0.9810000061988831},{"id":"https://openalex.org/keywords/dendritic-cells","display_name":"dendritic cells","score":0.9430000185966492},{"id":"https://openalex.org/keywords/macrophages","display_name":"macrophages","score":0.8479999899864197}],"concepts":[{"id":"https://openalex.org/C2778166374","wikidata":"https://www.wikidata.org/wiki/Q29938","display_name":"House dust mite","level":4,"score":0.726048469543457},{"id":"https://openalex.org/C2777961210","wikidata":"https://www.wikidata.org/wiki/Q927148","display_name":"Bronchoalveolar lavage","level":3,"score":0.6516759395599365},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6495095491409302},{"id":"https://openalex.org/C2777037409","wikidata":"https://www.wikidata.org/wiki/Q107238","display_name":"Eosinophil","level":3,"score":0.60976243019104},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.604809045791626},{"id":"https://openalex.org/C2779777708","wikidata":"https://www.wikidata.org/wiki/Q6033622","display_name":"Inhalation exposure","level":3,"score":0.5055527687072754},{"id":"https://openalex.org/C2776238763","wikidata":"https://www.wikidata.org/wiki/Q3801533","display_name":"Bronchial hyperresponsiveness","level":4,"score":0.4580783247947693},{"id":"https://openalex.org/C2776954882","wikidata":"https://www.wikidata.org/wiki/Q840343","display_name":"Inhalation","level":2,"score":0.42433372139930725},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4186502695083618},{"id":"https://openalex.org/C2775941134","wikidata":"https://www.wikidata.org/wiki/Q813622","display_name":"Goblet cell","level":3,"score":0.41766759753227234},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.3670307397842407},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.3476303219795227},{"id":"https://openalex.org/C2776178081","wikidata":"https://www.wikidata.org/wiki/Q3286546","display_name":"Respiratory disease","level":3,"score":0.23622292280197144},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.22834450006484985},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.16990739107131958},{"id":"https://openalex.org/C529295009","wikidata":"https://www.wikidata.org/wiki/Q41301","display_name":"Epithelium","level":2,"score":0.156072735786438},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1492249071598053},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0},{"id":"https://openalex.org/C2780510475","wikidata":"https://www.wikidata.org/wiki/Q186752","display_name":"Allergen","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002563","descriptor_name":"Cerium","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D002563","descriptor_name":"Cerium","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007370","descriptor_name":"Interferon Type I","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007370","descriptor_name":"Interferon Type I","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D019570","descriptor_name":"Inhalation Exposure","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D039981","descriptor_name":"Pyroglyphidae","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D050838","descriptor_name":"Interferon Regulatory Factor-3","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D050838","descriptor_name":"Interferon Regulatory Factor-3","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D053758","descriptor_name":"Nanoparticles","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D053758","descriptor_name":"Nanoparticles","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D056151","descriptor_name":"Airway Remodeling","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D056151","descriptor_name":"Airway Remodeling","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":8,"locations":[{"id":"doi:10.1186/s12989-018-0261-5","doi":"https://doi.org/10.1186/s12989-018-0261-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12989-018-0261-5","pdf_url":"https://particleandfibretoxicology.biomedcentral.com/counter/pdf/10.1186/s12989-018-0261-5","source":{"id":"https://openalex.org/S189275214","display_name":"Particle and Fibre Toxicology","issn_l":"1743-8977","issn":["1743-8977"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Particle and Fibre Toxicology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4921670","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5966909","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5966909","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5966909","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Part Fibre Toxicol","raw_type":"Text"},{"id":"pmid:29792201","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29792201","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Particle and fibre toxicology","raw_type":"Journal Article"},{"id":"pmh:oai:kclpure.kcl.ac.uk:openaire/21f8907c-11c9-4f92-829d-bfc75810ac94","doi":null,"is_oa":true,"landing_page_url":"https://kclpure.kcl.ac.uk/portal/en/publications/21f8907c-11c9-4f92-829d-bfc75810ac94","pdf_url":null,"source":{"id":"https://openalex.org/S4306400216","display_name":"Research Portal (King's College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I183935753","host_organization_name":"King's College London","host_organization_lineage":["https://openalex.org/I183935753"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Meldrum, K, Robertson, S B, R\u00f6mer, I, Marczylo, T, Dean, L S N, Rogers, A, Gant, T W, Smith, R, Tetley, T D & Leonard, M O 2018, 'Cerium dioxide nanoparticles exacerbate house dust mite induced type II airway inflammation', Particle And Fibre Toxicology, vol. 15, no. 1, 24. https://doi.org/10.1186/s12989-018-0261-5","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:3f9124a3d0664f8c801e320808f3a0ca","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/3f9124a3d0664f8c801e320808f3a0ca","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Particle and Fibre Toxicology, Vol 15, Iss 1, Pp 1-19 (2018)","raw_type":"article"},{"id":"pmh:oai:eprints.soton.ac.uk:474744","doi":null,"is_oa":false,"landing_page_url":"https://eprints.soton.ac.uk/474744/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401019","display_name":"ePrints Soton (University of Southampton)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I43439940","host_organization_name":"University of Southampton","host_organization_lineage":["https://openalex.org/I43439940"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:spiral.imperial.ac.uk:10044/1/60630","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10044/1/60630","pdf_url":null,"source":{"id":"https://openalex.org/S4306401396","display_name":"Spiral (Imperial College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I47508984","host_organization_name":"Imperial College London","host_organization_lineage":["https://openalex.org/I47508984"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1186/s12989-018-0261-5","doi":"https://doi.org/10.1186/s12989-018-0261-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12989-018-0261-5","pdf_url":"https://particleandfibretoxicology.biomedcentral.com/counter/pdf/10.1186/s12989-018-0261-5","source":{"id":"https://openalex.org/S189275214","display_name":"Particle and Fibre Toxicology","issn_l":"1743-8977","issn":["1743-8977"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Particle and Fibre Toxicology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9763000011444092}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320318095","display_name":"National Institute for Health Research Health Protection Research Unit","ror":null},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320320285","display_name":"King's College London","ror":"https://ror.org/0220mzb33"},{"id":"https://openalex.org/F4320321067","display_name":"Public Health England","ror":"https://ror.org/00vbvha87"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2806581632.pdf","grobid_xml":"https://content.openalex.org/works/W2806581632.grobid-xml"},"referenced_works_count":63,"referenced_works":["https://openalex.org/W150589858","https://openalex.org/W584371072","https://openalex.org/W1549131601","https://openalex.org/W1562080471","https://openalex.org/W1917984881","https://openalex.org/W1967157733","https://openalex.org/W1970742864","https://openalex.org/W1985035725","https://openalex.org/W1989104319","https://openalex.org/W2005505978","https://openalex.org/W2006744847","https://openalex.org/W2021826541","https://openalex.org/W2025554794","https://openalex.org/W2027912899","https://openalex.org/W2033358607","https://openalex.org/W2039660500","https://openalex.org/W2043310292","https://openalex.org/W2046839162","https://openalex.org/W2055409409","https://openalex.org/W2061435251","https://openalex.org/W2079847100","https://openalex.org/W2081618808","https://openalex.org/W2082624887","https://openalex.org/W2083218438","https://openalex.org/W2083559318","https://openalex.org/W2087023256","https://openalex.org/W2087714421","https://openalex.org/W2089507620","https://openalex.org/W2098125669","https://openalex.org/W2101664092","https://openalex.org/W2111893737","https://openalex.org/W2113570783","https://openalex.org/W2120166044","https://openalex.org/W2125148265","https://openalex.org/W2126948841","https://openalex.org/W2130251229","https://openalex.org/W2134596993","https://openalex.org/W2134619734","https://openalex.org/W2135286040","https://openalex.org/W2142584363","https://openalex.org/W2146007516","https://openalex.org/W2146036781","https://openalex.org/W2156188810","https://openalex.org/W2159522232","https://openalex.org/W2162902890","https://openalex.org/W2165978646","https://openalex.org/W2179695532","https://openalex.org/W2269523931","https://openalex.org/W2310415701","https://openalex.org/W2331994512","https://openalex.org/W2343858810","https://openalex.org/W2460841433","https://openalex.org/W2514225555","https://openalex.org/W2581785401","https://openalex.org/W2605922486","https://openalex.org/W2611509799","https://openalex.org/W2611600531","https://openalex.org/W2735396415","https://openalex.org/W2739873258","https://openalex.org/W2742332607","https://openalex.org/W2751184724","https://openalex.org/W2761727637","https://openalex.org/W2770207270"],"related_works":["https://openalex.org/W6927006453","https://openalex.org/W2979659687","https://openalex.org/W6921123829","https://openalex.org/W6939660967","https://openalex.org/W4384662915","https://openalex.org/W2160700027","https://openalex.org/W2462128565","https://openalex.org/W2111893737","https://openalex.org/W2178606820","https://openalex.org/W3008433586"],"abstract_inverted_index":{"Nanomaterial":[0],"inhalation":[1],"represents":[2],"a":[3,56,82,172,251,331],"potential":[4],"hazard":[5],"for":[6,30,351,364],"respiratory":[7],"conditions":[8],"such":[9],"as":[10,294],"asthma.":[11,65],"Cerium":[12],"dioxide":[13],"nanoparticles":[14],"(CeO":[15],"2":[16,53,71,134,164,177,203,268,301,314,359],"NPs)":[17],"have":[18,26,212,349],"the":[19,49,74,79,118,194,206,273,320],"ability":[20],"to":[21,47,175,180,219,307,318,324,357,367],"modify":[22],"disease":[23],"outcome":[24],"but":[25,188],"not":[27,160,211],"been":[28],"investigated":[29],"their":[31],"effect":[32],"on":[33],"models":[34],"of":[35,43,51,64,69,76,81,144,199,208,254,275,286,339],"asthma":[36],"and":[37,98,110,120,124,127,154,258,282,291],"inflammatory":[38,85,121,186,334],"lung":[39],"disease.":[40,368],"The":[41],"aim":[42],"this":[44,337,346],"study":[45],"was":[46,103,217,264],"examine":[48],"impact":[50],"CeO":[52,70,133,163,176,202,267,300,313,358],"NPs":[54,72,135,165,178,204,269,302,315,360],"in":[55,73,107,117,139,157,183,191,193,205,230,241,250,272,298],"house":[57,325],"dust":[58,326],"mite":[59,327],"(HDM)":[60],"induced":[61,131,151],"murine":[62,321],"model":[63],"Repeated":[66,167],"intranasal":[67],"instillation":[68],"presence":[75],"HDM":[77,137,150,209,248,308],"caused":[78],"induction":[80,253],"type":[83,184,255,310,332,338],"II":[84,185,311,333],"response,":[86],"characterised":[87],"by":[88,105,132,171],"increased":[89,234],"bronchoalveolar":[90],"lavage":[91],"eosinophils,":[92],"mast":[93],"cells,":[94,288],"total":[95],"plasma":[96],"IgE":[97],"goblet":[99],"cell":[100],"metaplasia.":[101],"This":[102],"accompanied":[104],"increases":[106,116],"IL-4,":[108],"CCL11":[109],"MCPT1":[111],"gene":[112,261],"expression":[113,232,274],"together":[114],"with":[115,162,201,266],"mucin":[119],"regulators":[122],"CLCA1":[123,126],"SLC26A4.":[125],"SLC26A4":[128],"were":[129,159,246,316],"also":[130],"+":[136],"co-exposure":[138],"air":[140],"liquid":[141],"interface":[142],"cultures":[143],"human":[145],"primary":[146],"bronchial":[147],"epithelial":[148],"cells.":[149],"airway":[152,155],"hyperresponsiveness":[153],"remodelling":[156],"mice":[158,200],"altered":[161],"co-exposure.":[166,270],"HMD":[168],"instillations":[169],"followed":[170],"single":[173,226],"exposure":[174,329,356],"failed":[179],"produce":[181],"changes":[182,240],"endpoints":[187],"did":[189,210],"result":[190],"alterations":[192],"neutrophil":[195,235],"marker":[196],"CD177.":[197],"Treatment":[198],"absence":[207],"any":[213],"significant":[214],"effects.":[215],"RNA-SEQ":[216],"used":[218],"explore":[220],"early":[221,296],"effects":[222],"24":[223],"h":[224],"after":[225],"treatment":[227],"exposures.":[228],"Changes":[229,271],"SAA3":[231],"paralleled":[233],"BAL":[236],"levels,":[237],"while":[238],"no":[239],"eosinophil":[242],"or":[243,354],"lymphocyte":[244],"levels":[245],"observed.":[247],"resulted":[249],"strong":[252],"I":[256],"interferon":[257],"IRF3":[259,292],"dependent":[260],"expression,":[262],"which":[263],"inhibited":[265],"genes":[276],"including":[277],"CCL20,":[278],"CXCL10,":[279],"NLRC5,":[280],"IRF7":[281],"CLEC10A":[283],"suggest":[284],"regulation":[285],"dendritic":[287],"macrophage":[289],"functionality":[290],"modulation":[293],"key":[295],"events":[297],"how":[299,352],"may":[303,348],"guide":[304],"pulmonary":[305,322],"responses":[306],"towards":[309,330],"inflammation.":[312],"observed":[317],"modulate":[319],"response":[323,340],"allergen":[328],"environment.":[335],"As":[336],"is":[341],"present":[342],"within":[343],"asthmatic":[344],"endotypes":[345],"finding":[347],"implications":[350],"occupational":[353],"incidental":[355],"should":[361],"be":[362],"considered":[363],"those":[365],"susceptible":[366]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-06-13T00:00:00"}