{"id":"https://openalex.org/W2805937880","doi":"https://doi.org/10.48550/arxiv.1805.11178","title":"Towards computational fluorescence microscopy: Machine learning-based integrated prediction of morphological and molecular tumor profiles","display_name":"Towards computational fluorescence microscopy: Machine learning-based integrated prediction of morphological and molecular tumor profiles","publication_year":2018,"publication_date":"2018-05-28","ids":{"openalex":"https://openalex.org/W2805937880","doi":"https://doi.org/10.48550/arxiv.1805.11178","mag":"2805937880"},"language":"en","primary_location":{"id":"pmh:oai:arXiv.org:1805.11178","doi":null,"is_oa":true,"landing_page_url":"http://arxiv.org/abs/1805.11178","pdf_url":"https://arxiv.org/pdf/1805.11178","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["arxiv","datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://arxiv.org/pdf/1805.11178","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072460783","display_name":"Alexander Binder","orcid":"https://orcid.org/0000-0001-9605-6209","observed_orcids":["https://orcid.org/0000-0001-9605-6209"]},"institutions":[{"id":"https://openalex.org/I152815399","display_name":"Singapore University of Technology and Design","ror":"https://ror.org/05j6fvn87","country_code":"SG","type":"education","lineage":["https://openalex.org/I152815399"]},{"id":"https://openalex.org/I4577782","display_name":"Technische Universit\u00e4t Berlin","ror":"https://ror.org/03v4gjf40","country_code":"DE","type":"education","lineage":["https://openalex.org/I4577782"]}],"countries":["DE","SG"],"is_corresponding":false,"raw_author_name":"Binder, Alexander","raw_affiliation_strings":["ISTD Pillar , Singapore University of Technology and Design , 8 Somapah Road , 487372 Sin- gapore","Machine-Learning Group , Department of Software Engineering and Theoretical Computer Science , Technical University of Berlin , Marchstr. 23 , 10587 Berlin , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ISTD Pillar , Singapore University of Technology and Design , 8 Somapah Road , 487372 Sin- gapore","institution_ids":["https://openalex.org/I152815399"]},{"raw_affiliation_string":"Machine-Learning Group , Department of Software Engineering and Theoretical Computer Science , Technical University of Berlin , Marchstr. 23 , 10587 Berlin , Germany","institution_ids":["https://openalex.org/I4577782"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082541553","display_name":"Michael Ludwig Bockmayr","orcid":"https://orcid.org/0000-0002-9249-4292","observed_orcids":["https://orcid.org/0000-0002-9249-4292"]},"institutions":[{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Bockmayr, Michael","raw_affiliation_strings":["Department of Pediatric Hematology and Oncology University Medical Center Hamburg- Eppendorf , Hamburg , Germany","Systems Pathology Lab , Institute of Pathology , Charit\u00e9 University Hospital , Charit\u00e9platz 1 , 10117 Berlin , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Hematology and Oncology University Medical Center Hamburg- Eppendorf , Hamburg , Germany","institution_ids":["https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Systems Pathology Lab , Institute of Pathology , Charit\u00e9 University Hospital , Charit\u00e9platz 1 , 10117 Berlin , Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038944725","display_name":"Miriam H\u00e4gele","orcid":"https://orcid.org/0000-0001-9251-5420","observed_orcids":["https://orcid.org/0000-0001-9251-5420"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H\u00e4gele, Miriam","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072688829","display_name":"Stephan Wienert","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Wienert, Stephan","raw_affiliation_strings":["Systems Pathology Lab , Institute of Pathology , Charit\u00e9 University Hospital , Charit\u00e9platz 1 , 10117 Berlin , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Systems Pathology Lab , Institute of Pathology , Charit\u00e9 University Hospital , Charit\u00e9platz 1 , 10117 Berlin , Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102753351","display_name":"Daniel Heim","orcid":"https://orcid.org/0000-0002-3809-1417","observed_orcids":["https://orcid.org/0000-0002-3809-1417"]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Heim, Daniel","raw_affiliation_strings":["Systems Pathology Lab , Institute of Pathology , Charit\u00e9 University Hospital , Charit\u00e9platz 1 , 10117 Berlin , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Systems Pathology Lab , Institute of Pathology , Charit\u00e9 University Hospital , Charit\u00e9platz 1 , 10117 Berlin , Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021985303","display_name":"Katharina Hellweg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Hellweg, Katharina","raw_affiliation_strings":["Department of Internal Medicine , Infectious Diseases and Pulmology Charit\u00e9platz 1 , 10117 Berlin , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine , Infectious Diseases and Pulmology Charit\u00e9platz 1 , 10117 Berlin , Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026607584","display_name":"Albrecht Stenzinger","orcid":"https://orcid.org/0000-0003-1001-103X","observed_orcids":["https://orcid.org/0000-0003-1001-103X"]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stenzinger, Albrecht","raw_affiliation_strings":["Institute of Pathology , University of Heidelberg , Im Neuenheimer Feld 224 , Heidelberg , Ger - many"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Pathology , University of Heidelberg , Im Neuenheimer Feld 224 , Heidelberg , Ger - many","institution_ids":["https://openalex.org/I223822909"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001642162","display_name":"Laura Parlow","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Parlow, Laura","raw_affiliation_strings":["Systems Pathology Lab , Institute of Pathology , Charit\u00e9 University Hospital , Charit\u00e9platz 1 , 10117 Berlin , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Systems Pathology Lab , Institute of Pathology , Charit\u00e9 University Hospital , Charit\u00e9platz 1 , 10117 Berlin , Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089035898","display_name":"Jan Budczies","orcid":"https://orcid.org/0000-0002-6668-5327","observed_orcids":["https://orcid.org/0000-0002-6668-5327"]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Budczies, Jan","raw_affiliation_strings":["Systems Pathology Lab , Institute of Pathology , Charit\u00e9 University Hospital , Charit\u00e9platz 1 , 10117 Berlin , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Systems Pathology Lab , Institute of Pathology , Charit\u00e9 University Hospital , Charit\u00e9platz 1 , 10117 Berlin , Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027386073","display_name":"Benjamin Frank Goeppert","orcid":"https://orcid.org/0000-0002-4135-9250","observed_orcids":["https://orcid.org/0000-0002-4135-9250"]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Goeppert, Benjamin","raw_affiliation_strings":["Institute of Pathology , University of Heidelberg , Im Neuenheimer Feld 224 , Heidelberg , Ger - many"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Pathology , University of Heidelberg , Im Neuenheimer Feld 224 , Heidelberg , Ger - many","institution_ids":["https://openalex.org/I223822909"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002077225","display_name":"Denise Treue","orcid":"https://orcid.org/0000-0002-0657-5505","observed_orcids":["https://orcid.org/0000-0002-0657-5505"]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Treue, Denise","raw_affiliation_strings":["Systems Pathology Lab , Institute of Pathology , Charit\u00e9 University Hospital , Charit\u00e9platz 1 , 10117 Berlin , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Systems Pathology Lab , Institute of Pathology , Charit\u00e9 University Hospital , Charit\u00e9platz 1 , 10117 Berlin , Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057171737","display_name":"Manato Kotani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405287342","display_name":"Immunology Frontier Research Center, The University of Osaka","ror":"https://ror.org/04xm7dy51","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4405287342","https://openalex.org/I98285908"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kotani, Manato","raw_affiliation_strings":["Laboratory of Cellular Dynamics , Immunology Frontier Research Center , Osaka University , 2-2 Yamada-oka , Suita , Osaka 565-0871 , Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Cellular Dynamics , Immunology Frontier Research Center , Osaka University , 2-2 Yamada-oka , Suita , Osaka 565-0871 , Japan","institution_ids":["https://openalex.org/I4405287342","https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058118162","display_name":"Masaru Ishii","orcid":"https://orcid.org/0000-0002-4215-007X","observed_orcids":["https://orcid.org/0000-0002-4215-007X"]},"institutions":[{"id":"https://openalex.org/I4405287342","display_name":"Immunology Frontier Research Center, The University of Osaka","ror":"https://ror.org/04xm7dy51","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4405287342","https://openalex.org/I98285908"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ishii, Masaru","raw_affiliation_strings":["Laboratory of Cellular Dynamics , Immunology Frontier Research Center , Osaka University , 2-2 Yamada-oka , Suita , Osaka 565-0871 , Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Cellular Dynamics , Immunology Frontier Research Center , Osaka University , 2-2 Yamada-oka , Suita , Osaka 565-0871 , Japan","institution_ids":["https://openalex.org/I4405287342","https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062227589","display_name":"Manfred Dietel","orcid":"https://orcid.org/0009-0001-4303-7837","observed_orcids":["https://orcid.org/0009-0001-4303-7837"]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dietel, Manfred","raw_affiliation_strings":["Systems Pathology Lab , Institute of Pathology , Charit\u00e9 University Hospital , Charit\u00e9platz 1 , 10117 Berlin , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Systems Pathology Lab , Institute of Pathology , Charit\u00e9 University Hospital , Charit\u00e9platz 1 , 10117 Berlin , Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021026009","display_name":"Andreas Christian Hocke","orcid":"https://orcid.org/0000-0002-6935-8612","observed_orcids":["https://orcid.org/0000-0002-6935-8612"]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Hocke, Andreas","raw_affiliation_strings":["Department of Internal Medicine , Infectious Diseases and Pulmology Charit\u00e9platz 1 , 10117 Berlin , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine , Infectious Diseases and Pulmology Charit\u00e9platz 1 , 10117 Berlin , Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033698551","display_name":"Carsten Denkert","orcid":"https://orcid.org/0000-0002-2249-0982","observed_orcids":["https://orcid.org/0000-0002-2249-0982"]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Denkert, Carsten","raw_affiliation_strings":["German Cancer Consortium (DKTK) , Charit\u00e9 , Berlin Charit\u00e9platz 1 , 10117 Berlin , Germany","Systems Pathology Lab , Institute of Pathology , Charit\u00e9 University Hospital , Charit\u00e9platz 1 , 10117 Berlin , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"German Cancer Consortium (DKTK) , Charit\u00e9 , Berlin Charit\u00e9platz 1 , 10117 Berlin , Germany","institution_ids":["https://openalex.org/I7877124"]},{"raw_affiliation_string":"Systems Pathology Lab , Institute of Pathology , Charit\u00e9 University Hospital , Charit\u00e9platz 1 , 10117 Berlin , Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107838719","display_name":"Klaus\u2010Robert M\u00fcller","orcid":"https://orcid.org/0000-0002-3861-7685","observed_orcids":["https://orcid.org/0000-0002-3861-7685"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M\u00fcller, Klaus-Robert","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5058109622","display_name":"Frederick Klauschen","orcid":"https://orcid.org/0000-0002-9131-2389","observed_orcids":["https://orcid.org/0000-0002-9131-2389"]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Klauschen, Frederick","raw_affiliation_strings":["German Cancer Consortium (DKTK) , Charit\u00e9 , Berlin Charit\u00e9platz 1 , 10117 Berlin , Germany","Systems Pathology Lab , Institute of Pathology , Charit\u00e9 University Hospital , Charit\u00e9platz 1 , 10117 Berlin , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"German Cancer Consortium (DKTK) , Charit\u00e9 , Berlin Charit\u00e9platz 1 , 10117 Berlin , Germany","institution_ids":["https://openalex.org/I7877124"]},{"raw_affiliation_string":"Systems Pathology Lab , Institute of Pathology , Charit\u00e9 University Hospital , Charit\u00e9platz 1 , 10117 Berlin , Germany","institution_ids":["https://openalex.org/I7877124"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":30,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9101999998092651,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9101999998092651,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.05990000069141388,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.013100000098347664,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.8870000243186951},{"id":"https://openalex.org/keywords/tumor-morphology","display_name":"tumor morphology","score":0.7310000061988831},{"id":"https://openalex.org/keywords/molecular-profiling","display_name":"molecular profiling","score":0.7770000100135803},{"id":"https://openalex.org/keywords/machine-learning","display_name":"machine learning","score":0.5580000281333923},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"tumor microenvironment","score":0.777999997138977},{"id":"https://openalex.org/keywords/protein-expression","display_name":"protein expression","score":0.6940000057220459},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.9259999990463257},{"id":"https://openalex.org/keywords/copy-number-variation","display_name":"copy number variation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.8360000252723694},{"id":"https://openalex.org/keywords/somatic-mutations","display_name":"somatic mutations","score":1.0}],"concepts":[{"id":"https://openalex.org/C187191949","wikidata":"https://www.wikidata.org/wiki/Q1138496","display_name":"Profiling (computer programming)","level":2,"score":0.5712878108024597},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5040606260299683},{"id":"https://openalex.org/C136339569","wikidata":"https://www.wikidata.org/wiki/Q1142297","display_name":"Molecular imaging","level":3,"score":0.45264437794685364},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.38187599182128906},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3797028958797455},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.34462350606918335},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13808709383010864},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:arXiv.org:1805.11178","doi":null,"is_oa":true,"landing_page_url":"http://arxiv.org/abs/1805.11178","pdf_url":"https://arxiv.org/pdf/1805.11178","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"doi:10.48550/arxiv.1805.11178","doi":"https://doi.org/10.48550/arxiv.1805.11178","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.1805.11178","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Preprint"}],"best_oa_location":{"id":"pmh:oai:arXiv.org:1805.11178","doi":null,"is_oa":true,"landing_page_url":"http://arxiv.org/abs/1805.11178","pdf_url":"https://arxiv.org/pdf/1805.11178","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"sustainable_development_goals":[{"score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2156757918","display_name":null,"funder_award_id":"2017-0-00451","funder_id":"https://openalex.org/F4320335489","funder_display_name":"Institute for Information and Communications Technology Promotion"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320321114","display_name":"Bundesministerium f\u00fcr Bildung und Forschung","ror":"https://ror.org/04pz7b180"},{"id":"https://openalex.org/F4320323688","display_name":"Einstein Stiftung Berlin","ror":"https://ror.org/03s0fv852"},{"id":"https://openalex.org/F4320324094","display_name":"Technische Universit\u00e4t Berlin","ror":"https://ror.org/03v4gjf40"},{"id":"https://openalex.org/F4320324110","display_name":"Singapore University of Technology and Design","ror":"https://ror.org/05j6fvn87"},{"id":"https://openalex.org/F4320327569","display_name":"Deutschen Konsortium f\u00fcr Translationale Krebsforschung","ror":"https://ror.org/02pqn3g31"},{"id":"https://openalex.org/F4320335489","display_name":"Institute for Information and Communications Technology Promotion","ror":"https://ror.org/01g0hqq23"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2805937880.pdf","grobid_xml":"https://content.openalex.org/works/W2805937880.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W110099803","https://openalex.org/W146996797","https://openalex.org/W1571024744","https://openalex.org/W1680439812","https://openalex.org/W1873896754","https://openalex.org/W1996384179","https://openalex.org/W2029230372","https://openalex.org/W2063879956","https://openalex.org/W2066941820","https://openalex.org/W2078682753","https://openalex.org/W2103012681","https://openalex.org/W2103243046","https://openalex.org/W2106503792","https://openalex.org/W2108995755","https://openalex.org/W2110065044","https://openalex.org/W2110243528","https://openalex.org/W2124379487","https://openalex.org/W2127513583","https://openalex.org/W2130410032","https://openalex.org/W2136502970","https://openalex.org/W2145406111","https://openalex.org/W2146875866","https://openalex.org/W2151103935","https://openalex.org/W2158394179","https://openalex.org/W2165612380","https://openalex.org/W2195388612","https://openalex.org/W2240067561","https://openalex.org/W2479420012","https://openalex.org/W2514628397","https://openalex.org/W2558654560","https://openalex.org/W2741730513","https://openalex.org/W2749536232","https://openalex.org/W2768109071","https://openalex.org/W2771978163","https://openalex.org/W2804540468","https://openalex.org/W2964231383"],"related_works":["https://openalex.org/W3135345798","https://openalex.org/W2980155313","https://openalex.org/W4285089081","https://openalex.org/W4395686880","https://openalex.org/W2884716214","https://openalex.org/W4411691978","https://openalex.org/W2964047652","https://openalex.org/W4245310656","https://openalex.org/W7080970286","https://openalex.org/W4404130837"],"abstract_inverted_index":{"Recent":[0],"advances":[1],"in":[2,10],"cancer":[3,59,102],"research":[4],"largely":[5],"rely":[6],"on":[7],"new":[8],"developments":[9],"microscopic":[11],"or":[12,26,76],"molecular":[13,27,55,71,94],"profiling":[14,72],"techniques":[15],"offering":[16],"high":[17],"level":[18],"of":[19,47,54,64,67],"detail":[20],"with":[21,69,96],"respect":[22,97],"to":[23,91,98,101],"either":[24],"spatial":[25,105],"features,":[28],"but":[29],"usually":[30],"not":[31],"both.":[32],"Here,":[33],"we":[34],"present":[35],"a":[36,88],"novel":[37,89],"machine":[38],"learning-based":[39],"computational":[40],"approach":[41],"that":[42],"allows":[43],"for":[44],"the":[45,52,108],"identification":[46],"morphological":[48],"tissue":[49],"features":[50],"and":[51,84,103],"prediction":[53],"properties":[56],"from":[57],"breast":[58],"imaging":[60],"data.":[61],"This":[62],"integration":[63],"microanatomic":[65],"information":[66],"tumors":[68],"complex":[70],"data,":[73],"including":[74],"protein":[75],"gene":[77,82],"expression,":[78],"copy":[79],"number":[80],"variation,":[81],"methylation":[83],"somatic":[85],"mutations,":[86],"provides":[87],"means":[90],"computationally":[92],"score":[93],"markers":[95],"their":[99,104],"relevance":[100],"associations":[106],"within":[107],"tumor":[109],"microenvironment.":[110]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2018-06-13T00:00:00"}