{"id":"https://openalex.org/W2805743352","doi":"https://doi.org/10.3389/fpls.2018.00779","title":"Subunit Interaction Differences Between the Replication Factor C Complexes in Arabidopsis and Rice","display_name":"Subunit Interaction Differences Between the Replication Factor C Complexes in Arabidopsis and Rice","publication_year":2018,"publication_date":"2018-06-19","ids":{"openalex":"https://openalex.org/W2805743352","doi":"https://doi.org/10.3389/fpls.2018.00779","mag":"2805743352","pmid":"https://pubmed.ncbi.nlm.nih.gov/29971074","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6018503"},"language":"en","primary_location":{"id":"doi:10.3389/fpls.2018.00779","doi":"https://doi.org/10.3389/fpls.2018.00779","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fpls.2018.00779","pdf_url":"https://www.frontiersin.org/articles/10.3389/fpls.2018.00779/pdf","source":{"id":"https://openalex.org/S2493613807","display_name":"Frontiers in Plant Science","issn_l":"1664-462X","issn":["1664-462X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Plant Science","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fpls.2018.00779/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001618242","display_name":"Yueyue Chen","orcid":"https://orcid.org/0000-0001-6167-1690","observed_orcids":["https://orcid.org/0000-0001-6167-1690"]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yueyue Chen","raw_affiliation_strings":["State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan, China","institution_ids":["https://openalex.org/I37461747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039392370","display_name":"Jie Qian","orcid":"https://orcid.org/0000-0002-4244-1811","observed_orcids":["https://orcid.org/0000-0002-4244-1811"]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Qian","raw_affiliation_strings":["State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan, China","institution_ids":["https://openalex.org/I37461747"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Li You","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li You","raw_affiliation_strings":["State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan, China","institution_ids":["https://openalex.org/I37461747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077986501","display_name":"Xiufeng Zhang","orcid":"https://orcid.org/0000-0001-6707-3958","observed_orcids":["https://orcid.org/0000-0001-6707-3958"]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiufeng Zhang","raw_affiliation_strings":["State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan, China","institution_ids":["https://openalex.org/I37461747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035357453","display_name":"Jinxia Jiao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jinxia Jiao","raw_affiliation_strings":["State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan, China","institution_ids":["https://openalex.org/I37461747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003777866","display_name":"Yang Liu","orcid":"https://orcid.org/0000-0001-8364-1476","observed_orcids":["https://orcid.org/0000-0001-8364-1476"]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yang Liu","raw_affiliation_strings":["State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan, China","institution_ids":["https://openalex.org/I37461747"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080661603","display_name":"Jie Zhao","orcid":"https://orcid.org/0000-0002-7622-8904","observed_orcids":["https://orcid.org/0000-0002-7622-8904"]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jie Zhao","raw_affiliation_strings":["State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan, China","institution_ids":["https://openalex.org/I37461747"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5080661603"],"corresponding_institution_ids":["https://openalex.org/I37461747"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":1.0146,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.73783792,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"9","issue":null,"first_page":"779","last_page":"779"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.6753000020980835,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.6753000020980835,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.25270000100135803,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.010200000368058681,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/replication-factor-c","display_name":"replication factor C","score":0.9309999942779541},{"id":"https://openalex.org/keywords/dna-replication","display_name":"DNA replication","score":0.8330000042915344},{"id":"https://openalex.org/keywords/subunit-interactions","display_name":"subunit interactions","score":0.722000002861023},{"id":"https://openalex.org/keywords/protein-complex-structure","display_name":"protein complex structure","score":0.6190000176429749},{"id":"https://openalex.org/keywords/arabidopsis-thaliana","display_name":"Arabidopsis thaliana","score":0.8989999890327454},{"id":"https://openalex.org/keywords/rice","display_name":"rice","score":0.9539999961853027},{"id":"https://openalex.org/keywords/subcellular-localization","display_name":"subcellular localization","score":0.8040000200271606},{"id":"https://openalex.org/keywords/c-terminal-interaction-domain","display_name":"C-terminal interaction domain","score":0.6309999823570251}],"concepts":[{"id":"https://openalex.org/C123243835","wikidata":"https://www.wikidata.org/wiki/Q863465","display_name":"Bimolecular fluorescence complementation","level":3,"score":0.9070272445678711},{"id":"https://openalex.org/C2779491563","wikidata":"https://www.wikidata.org/wiki/Q157892","display_name":"Arabidopsis","level":4,"score":0.7776901721954346},{"id":"https://openalex.org/C104292427","wikidata":"https://www.wikidata.org/wiki/Q899781","display_name":"Protein subunit","level":3,"score":0.6993873715400696},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6150501370429993},{"id":"https://openalex.org/C2777576037","wikidata":"https://www.wikidata.org/wiki/Q719725","display_name":"Saccharomyces cerevisiae","level":3,"score":0.6132878661155701},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5877901315689087},{"id":"https://openalex.org/C188082640","wikidata":"https://www.wikidata.org/wiki/Q1780899","display_name":"Complementation","level":4,"score":0.5854772925376892},{"id":"https://openalex.org/C190062978","wikidata":"https://www.wikidata.org/wiki/Q79899","display_name":"Cytoplasm","level":2,"score":0.5499340295791626},{"id":"https://openalex.org/C2776879804","wikidata":"https://www.wikidata.org/wiki/Q7630919","display_name":"Subcellular localization","level":3,"score":0.5366935133934021},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.505071222782135},{"id":"https://openalex.org/C73573662","wikidata":"https://www.wikidata.org/wiki/Q130996","display_name":"DNA replication","level":3,"score":0.48600777983665466},{"id":"https://openalex.org/C113442657","wikidata":"https://www.wikidata.org/wiki/Q25624","display_name":"Endosperm","level":2,"score":0.4833616614341736},{"id":"https://openalex.org/C131140672","wikidata":"https://www.wikidata.org/wiki/Q2031164","display_name":"Processivity","level":4,"score":0.4300379753112793},{"id":"https://openalex.org/C115867849","wikidata":"https://www.wikidata.org/wiki/Q753175","display_name":"Protein-fragment complementation assay","level":5,"score":0.42951396107673645},{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.3951547145843506},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3278454542160034},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.3075152039527893},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.23534035682678223}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3389/fpls.2018.00779","doi":"https://doi.org/10.3389/fpls.2018.00779","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fpls.2018.00779","pdf_url":"https://www.frontiersin.org/articles/10.3389/fpls.2018.00779/pdf","source":{"id":"https://openalex.org/S2493613807","display_name":"Frontiers in Plant Science","issn_l":"1664-462X","issn":["1664-462X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Plant Science","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4979106","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6018503","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:29971074","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29971074","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in plant science","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6018503","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6018503/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Plant Sci","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:72592ef97d4f4e1e94f93a7b13aeda51","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/72592ef97d4f4e1e94f93a7b13aeda51","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Plant Science, Vol 9 (2018)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fpls.2018.00779","doi":"https://doi.org/10.3389/fpls.2018.00779","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fpls.2018.00779","pdf_url":"https://www.frontiersin.org/articles/10.3389/fpls.2018.00779/pdf","source":{"id":"https://openalex.org/S2493613807","display_name":"Frontiers in Plant Science","issn_l":"1664-462X","issn":["1664-462X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Plant Science","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4921525136","display_name":"\u6c34\u7a3b\u548c\u62df\u5357\u82a5\u751f\u6b96\u53d1\u80b2\u4e2dRFC\u57fa\u56e0\u7684\u8c03\u63a7\u673a\u5236","funder_award_id":"31370348","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6018889636","display_name":"\u6c34\u7a3bFMD1\u548cFMD2\u57fa\u56e0\u8c03\u63a7\u96cc\u914d\u5b50\u4f53\u53d1\u80b2\u7684\u5206\u5b50\u673a\u5236","funder_award_id":"31670312","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2805743352.pdf","grobid_xml":"https://content.openalex.org/works/W2805743352.grobid-xml"},"referenced_works_count":64,"referenced_works":["https://openalex.org/W1528622087","https://openalex.org/W1606996063","https://openalex.org/W1771989280","https://openalex.org/W1869438112","https://openalex.org/W1875835053","https://openalex.org/W1876719690","https://openalex.org/W1908340894","https://openalex.org/W1916339093","https://openalex.org/W1944079546","https://openalex.org/W1970872037","https://openalex.org/W1972533756","https://openalex.org/W1980225897","https://openalex.org/W1999292566","https://openalex.org/W2001731565","https://openalex.org/W2011074932","https://openalex.org/W2011359426","https://openalex.org/W2012822584","https://openalex.org/W2020977321","https://openalex.org/W2031453158","https://openalex.org/W2031747438","https://openalex.org/W2036028864","https://openalex.org/W2037431251","https://openalex.org/W2039274290","https://openalex.org/W2040150820","https://openalex.org/W2059060156","https://openalex.org/W2060020768","https://openalex.org/W2060665340","https://openalex.org/W2061537158","https://openalex.org/W2061628677","https://openalex.org/W2063026923","https://openalex.org/W2069352564","https://openalex.org/W2071953483","https://openalex.org/W2074565289","https://openalex.org/W2078194375","https://openalex.org/W2080140141","https://openalex.org/W2091790979","https://openalex.org/W2093072087","https://openalex.org/W2094785950","https://openalex.org/W2102335989","https://openalex.org/W2106049510","https://openalex.org/W2111202021","https://openalex.org/W2111936775","https://openalex.org/W2116122104","https://openalex.org/W2120044498","https://openalex.org/W2124964540","https://openalex.org/W2125121305","https://openalex.org/W2126196172","https://openalex.org/W2127886165","https://openalex.org/W2135378265","https://openalex.org/W2139425390","https://openalex.org/W2143968302","https://openalex.org/W2146279188","https://openalex.org/W2151229774","https://openalex.org/W2154773687","https://openalex.org/W2165823965","https://openalex.org/W2166738705","https://openalex.org/W2166903547","https://openalex.org/W2169871942","https://openalex.org/W2171780991","https://openalex.org/W2283974241","https://openalex.org/W2580680371","https://openalex.org/W2588544409","https://openalex.org/W2789831396","https://openalex.org/W4251927286"],"related_works":["https://openalex.org/W1972533756","https://openalex.org/W1970872037","https://openalex.org/W1972678271","https://openalex.org/W2951009608","https://openalex.org/W1982016916","https://openalex.org/W2034592392","https://openalex.org/W2353518815","https://openalex.org/W2183425927","https://openalex.org/W2074565289","https://openalex.org/W2106049510"],"abstract_inverted_index":{"Replication":[0],"factor":[1],"C":[2],"(RFC)":[3],"is":[4,25],"a":[5],"multisubunit":[6],"complex":[7,217,239],"that":[8,105,125,230,244],"opens":[9],"the":[10,17,47,52,68,82,87,111,133,144,161,175,179,196,206,213,223,233,245],"sliding":[11],"clamp":[12,53],"and":[13,24,36,40,49,64,81,84,98,103,107,116,127,137,146,153,165,171,185,247,253],"loads":[14],"it":[15],"onto":[16],"DNA":[18,30],"chain":[19],"in":[20,73,101,132,143,195,251],"an":[21],"ATP-dependent":[22],"manner":[23],"thus":[26],"critical":[27],"for":[28,79,216,238],"high-speed":[29],"synthesis.":[31],"In":[32,188],"yeast":[33,150],"(Saccharomyces":[34],"cerevisiae)":[35],"humans,":[37],"biochemical":[38],"studies":[39,242],"structural":[41],"analysis":[42,123],"revealed":[43,124],"interaction":[44,83],"patterns":[45],"between":[46],"subunits":[48,72,88,177,224,235],"architectures":[50],"of":[51,56,61,70,86,163,174,198,222,232,249],"loaders.":[54],"Mutations":[55],"ScRFC1/2/3/4/5":[57],"lead":[58],"to":[59],"loss":[60],"cell":[62],"viability":[63],"defective":[65],"replication.":[66],"However,":[67],"functions":[69],"RFC":[71,169,180,220,234],"higher":[74],"plants":[75],"are":[76,236,255],"unclear,":[77],"except":[78],"AtRFC1/3/4,":[80],"arrangement":[85],"have":[89],"not":[90],"been":[91],"studied.":[92],"Here,":[93],"we":[94,159],"identified":[95],"rfc2-1/+,":[96],"rfc3-2/+":[97],"rfc5-1/+":[99],"mutants":[100],"Arabidopsis,":[102],"found":[104],"embryos":[106],"endosperm":[108],"arrested":[109],"at":[110],"2/4-celled":[112],"embryo":[113],"proper":[114],"stage":[115],"6-8":[117],"nuclei":[118],"stages,":[119],"respectively.":[120,187],"Subcellular":[121],"localization":[122,246],"AtRFC1":[126,190],"OsRFC1/4/5":[128],"proteins":[129,139,221],"were":[130,140,183,225],"localized":[131],"nucleus,":[134],"while":[135,201],"AtRFC2/3/4/5":[136,194],"OsRFC2/3":[138],"present":[141],"both":[142],"nucleus":[145],"cytoplasm.":[147],"By":[148],"using":[149],"two-hybrid":[151],"(Y2H)":[152],"bimolecular":[154],"fluorescence":[155],"complementation":[156],"(BiFC)":[157],"techniques,":[158],"demonstrated":[160],"interactions":[162,248],"Arabidopsis":[164,252],"rice":[166,254],"(Oryza":[167],"sativa)":[168],"subunits,":[170,200],"proposed":[172],"arrangements":[173],"five":[176],"within":[178],"complex,":[181],"which":[182],"AtRFC5-AtRFC4-AtRFC3/2-AtRFC2/3-AtRFC1":[184],"OsRFC5-OsRFC2-OsRFC3-OsRFC4-OsRFC1,":[186],"addition,":[189],"could":[191],"interact":[192],"with":[193,205],"presence":[197],"other":[199,207],"OsRFC1":[202],"directly":[203],"interacted":[204],"four":[208],"subunits.":[209],"To":[210],"further":[211],"characterize":[212],"regions":[214],"required":[215,237],"formation,":[218],"truncated":[219],"created.":[226],"The":[227],"results":[228],"showed":[229],"C-termini":[231],"formation.":[240],"Our":[241],"indicate":[243],"RFCs":[250],"distinctly":[256],"discrepant.":[257]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2018-06-13T00:00:00"}