{"id":"https://openalex.org/W2805729465","doi":"https://doi.org/10.1038/s41420-017-0025-2","title":"Common medium versus advanced IVF medium for cryopreserved oocytes in heterologous cycles","display_name":"Common medium versus advanced IVF medium for cryopreserved oocytes in heterologous cycles","publication_year":2018,"publication_date":"2018-02-20","ids":{"openalex":"https://openalex.org/W2805729465","doi":"https://doi.org/10.1038/s41420-017-0025-2","mag":"2805729465","pmid":"https://pubmed.ncbi.nlm.nih.gov/29531831","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5841294"},"language":"en","primary_location":{"id":"doi:10.1038/s41420-017-0025-2","doi":"https://doi.org/10.1038/s41420-017-0025-2","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41420-017-0025-2","pdf_url":"https://www.nature.com/articles/s41420-017-0025-2.pdf","source":{"id":"https://openalex.org/S2764515074","display_name":"Cell Death Discovery","issn_l":"2058-7716","issn":["2058-7716"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Death Discovery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41420-017-0025-2.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067687615","display_name":"R. Poverini","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"R. Poverini","raw_affiliation_strings":["IVF Unit, Casa di Cura Villa Mafalda, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IVF Unit, Casa di Cura Villa Mafalda, Rome, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079958077","display_name":"Rosella Lisi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. Lisi","raw_affiliation_strings":["IVF Unit, Casa di Cura Villa Mafalda, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IVF Unit, Casa di Cura Villa Mafalda, Rome, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044508053","display_name":"Franco Lisi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F. Lisi","raw_affiliation_strings":["IVF Unit, Casa di Cura Villa Mafalda, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IVF Unit, Casa di Cura Villa Mafalda, Rome, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007215875","display_name":"V. Berlinghieri","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V. Berlinghieri","raw_affiliation_strings":["IVF Unit, Casa di Cura Villa Mafalda, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IVF Unit, Casa di Cura Villa Mafalda, Rome, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024899034","display_name":"W. Bielli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W. Bielli","raw_affiliation_strings":["IVF Unit, Casa di Cura Villa Mafalda, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IVF Unit, Casa di Cura Villa Mafalda, Rome, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010953686","display_name":"Pietro Carfagna","orcid":"https://orcid.org/0000-0002-4379-167X","observed_orcids":["https://orcid.org/0000-0002-4379-167X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P. Carfagna","raw_affiliation_strings":["IVF Unit, Casa di Cura Villa Mafalda, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IVF Unit, Casa di Cura Villa Mafalda, Rome, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"A. Costantino","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. Costantino","raw_affiliation_strings":["IVF Unit, Casa di Cura Villa Mafalda, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IVF Unit, Casa di Cura Villa Mafalda, Rome, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066124253","display_name":"D Iacomino","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D. Iacomino","raw_affiliation_strings":["IVF Unit, Casa di Cura Villa Mafalda, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IVF Unit, Casa di Cura Villa Mafalda, Rome, Italy","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056975347","display_name":"G. Nicodemo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G. Nicodemo","raw_affiliation_strings":["IVF Unit, Casa di Cura Villa Mafalda, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IVF Unit, Casa di Cura Villa Mafalda, Rome, Italy","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5067687615"],"corresponding_institution_ids":[],"apc_list":{"value":2690,"currency":"USD","value_usd":2690},"apc_paid":{"value":2690,"currency":"USD","value_usd":2690},"fwci":0.3969,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.59143339,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"4","issue":"1","first_page":"34","last_page":"34"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11156","display_name":"Reproductive Health and Technologies","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11732","display_name":"Assisted Reproductive Technology and Twin Pregnancy","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gm-csf","display_name":"GM-CSF","score":0.9279999732971191},{"id":"https://openalex.org/keywords/embryo-culture-medium","display_name":"embryo culture media","score":0.7889999747276306},{"id":"https://openalex.org/keywords/cryopreserved-oocytes","display_name":"cryopreserved oocytes","score":0.8450000286102295},{"id":"https://openalex.org/keywords/embryonic-development","display_name":"embryonic development","score":0.6740000247955322},{"id":"https://openalex.org/keywords/pregnancy-rate","display_name":"pregnancy rate","score":0.7979999780654907},{"id":"https://openalex.org/keywords/fertilization-rate","display_name":"fertilization rate","score":0.996999979019165},{"id":"https://openalex.org/keywords/embryo-quality","display_name":"embryo quality","score":0.8820000290870667},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.75}],"concepts":[{"id":"https://openalex.org/C179933525","wikidata":"https://www.wikidata.org/wiki/Q1144664","display_name":"Cryopreservation","level":3,"score":0.8575237989425659},{"id":"https://openalex.org/C2780115692","wikidata":"https://www.wikidata.org/wiki/Q5747302","display_name":"Heterologous","level":3,"score":0.7283905148506165},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.6753674745559692},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4364948868751526},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.275132417678833},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2314908802509308},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.22993668913841248},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1228790283203125},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1038/s41420-017-0025-2","doi":"https://doi.org/10.1038/s41420-017-0025-2","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41420-017-0025-2","pdf_url":"https://www.nature.com/articles/s41420-017-0025-2.pdf","source":{"id":"https://openalex.org/S2764515074","display_name":"Cell Death Discovery","issn_l":"2058-7716","issn":["2058-7716"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Death Discovery","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4753453","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5841294","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5841294","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5841294","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Death Discov","raw_type":"Text"},{"id":"pmid:29531831","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29531831","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell death discovery","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:e01e455bcc0c4e2eaeea4cb00cacf71a","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/e01e455bcc0c4e2eaeea4cb00cacf71a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cell Death Discovery, Vol 4, Iss 1, Pp 1-4 (2018)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41420-017-0025-2","doi":"https://doi.org/10.1038/s41420-017-0025-2","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41420-017-0025-2","pdf_url":"https://www.nature.com/articles/s41420-017-0025-2.pdf","source":{"id":"https://openalex.org/S2764515074","display_name":"Cell Death Discovery","issn_l":"2058-7716","issn":["2058-7716"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Death Discovery","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2805729465.pdf","grobid_xml":"https://content.openalex.org/works/W2805729465.grobid-xml"},"referenced_works_count":14,"referenced_works":["https://openalex.org/W1966091915","https://openalex.org/W1966558911","https://openalex.org/W1974522827","https://openalex.org/W1983439690","https://openalex.org/W2000598875","https://openalex.org/W2020564947","https://openalex.org/W2024365925","https://openalex.org/W2054886999","https://openalex.org/W2054964979","https://openalex.org/W2095422079","https://openalex.org/W2128982949","https://openalex.org/W2165508657","https://openalex.org/W2171450891","https://openalex.org/W2190125954"],"related_works":["https://openalex.org/W4313275131","https://openalex.org/W3132841452","https://openalex.org/W2120392829","https://openalex.org/W2000598875","https://openalex.org/W7167688629","https://openalex.org/W7167664086","https://openalex.org/W7105876807","https://openalex.org/W1988374168","https://openalex.org/W7167673527","https://openalex.org/W4283750278"],"abstract_inverted_index":{"Granulocyte-macrophage":[0],"colony-stimulation":[1,30],"factor":[2,31],"plays":[3],"different":[4,56,90,97],"crucial":[5],"roles":[6],"during":[7],"embryo":[8,21,34,87],"implantation":[9],"and":[10,36,86,108],"subsequent":[11],"development.":[12],"Here":[13],"we":[14,42],"aimed":[15],"to":[16,50],"evaluate":[17],"the":[18,26,52,81,104,109],"effects":[19],"of":[20,28,45,92,106,121],"cell":[22],"culture":[23,57],"medium,":[24],"with":[25,76,117],"inclusion":[27],"granulocyte-macrophage":[29],"(GM-CSF),":[32],"on":[33],"development":[35],"pregnancy":[37,84,110],"rate.":[38],"To":[39],"this":[40,62,118],"end,":[41],"took":[43],"advantage":[44],"our":[46,68],"retrospective":[47],"observational":[48],"study":[49,63],"correlate":[51],"outcomes":[53],"from":[54,67,95],"two":[55,96],"media.":[58],"We":[59,79],"included":[60],"in":[61],"25":[64],"unselected":[65],"patient":[66],"IVF":[69,74],"Center":[70],"that":[71,103],"underwent":[72],"heterologous":[73],"cycle":[75],"crypreserved":[77],"oocytes.":[78],"analyze":[80],"fertilization":[82,107],"rate,":[83,85],"quality":[88],"at":[89],"day":[91],"transfer":[93],"obtained":[94],"media":[98],"composition.":[99],"Our":[100],"results":[101],"show":[102],"rate":[105,111],"were":[112],"increased":[113],"using":[114],"medium":[115],"added":[116],"particular":[119],"type":[120],"cytokines":[122],"(GM-CSF).":[123]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2018-06-13T00:00:00"}