{"id":"https://openalex.org/W2805683189","doi":null,"title":"Investigating the Effects of Early and Current Thyroid Hormone Status on Higher-order Visual Abilities","display_name":"Investigating the Effects of Early and Current Thyroid Hormone Status on Higher-order Visual Abilities","publication_year":2012,"publication_date":"2012-08-31","ids":{"openalex":"https://openalex.org/W2805683189","mag":"2805683189"},"language":"en","primary_location":{"id":"pmh:oai:utoronto.scholaris.ca:1807/32889","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1807/32889","pdf_url":"https://utoronto.scholaris.ca/bitstreams/b3a679b9-b8d9-4e20-b881-63e4645d2aff/download","source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://utoronto.scholaris.ca/bitstreams/b3a679b9-b8d9-4e20-b881-63e4645d2aff/download","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030379608","display_name":"Nevena Simi\u0107","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Nevena Simi\u0107","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5030379608"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.8022000193595886,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.8022000193595886,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10427","display_name":"Visual perception and processing mechanisms","score":0.1273999959230423,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11015","display_name":"Down syndrome and intellectual disability research","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/congenital-hypothyroidism","display_name":"congenital hypothyroidism","score":1.0},{"id":"https://openalex.org/keywords/dorsal-visual-stream","display_name":"dorsal stream","score":0.9620000123977661},{"id":"https://openalex.org/keywords/ventral-stream","display_name":"ventral stream","score":0.9909999966621399},{"id":"https://openalex.org/keywords/mental-rotation","display_name":"mental rotation","score":0.6650000214576721},{"id":"https://openalex.org/keywords/spatial-localization","display_name":"spatial localization","score":0.7369999885559082},{"id":"https://openalex.org/keywords/organizational-effects","display_name":"organizational effects","score":0.6449999809265137},{"id":"https://openalex.org/keywords/activational-effects","display_name":"activational effects","score":0.9520000219345093},{"id":"https://openalex.org/keywords/visuospatial-impairment","display_name":"visuospatial impairment","score":0.6980000138282776},{"id":"https://openalex.org/keywords/children-and-adolescents","display_name":"children and adolescents","score":0.7670000195503235}],"concepts":[{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.5488461256027222},{"id":"https://openalex.org/C182306322","wikidata":"https://www.wikidata.org/wiki/Q1779371","display_name":"Order (exchange)","level":2,"score":0.4786716401576996},{"id":"https://openalex.org/C148043351","wikidata":"https://www.wikidata.org/wiki/Q4456944","display_name":"Current (fluid)","level":2,"score":0.4447781443595886},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.41430768370628357},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.35138410329818726},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3340480327606201},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.26075679063796997},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.1426962912082672},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.09650221467018127},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C10138342","wikidata":"https://www.wikidata.org/wiki/Q43015","display_name":"Finance","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:utoronto.scholaris.ca:1807/32889","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1807/32889","pdf_url":"https://utoronto.scholaris.ca/bitstreams/b3a679b9-b8d9-4e20-b881-63e4645d2aff/download","source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.470.9454","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.470.9454","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://tspace.library.utoronto.ca/bitstream/1807/32889/1/Simic_Nevena_201206_PhD_thesis.pdf","raw_type":"text"},{"id":"pmh:oai:collectionscanada.gc.ca:OTU.1807/32889","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1807/32889","pdf_url":null,"source":{"id":"https://openalex.org/S4306402307","display_name":"Library and Archives Canada (Government of Canada)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2802286613","host_organization_name":"Government of Canada","host_organization_lineage":["https://openalex.org/I2802286613"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:2805683189","doi":null,"is_oa":false,"landing_page_url":"https://tspace.library.utoronto.ca/bitstream/1807/32889/1/Simic_Nevena_201206_PhD_thesis.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:utoronto.scholaris.ca:1807/32889","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1807/32889","pdf_url":"https://utoronto.scholaris.ca/bitstreams/b3a679b9-b8d9-4e20-b881-63e4645d2aff/download","source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2805683189.pdf","grobid_xml":"https://content.openalex.org/works/W2805683189.grobid-xml"},"referenced_works_count":118,"referenced_works":["https://openalex.org/W11706560","https://openalex.org/W17801811","https://openalex.org/W178873621","https://openalex.org/W205734715","https://openalex.org/W1512965480","https://openalex.org/W1573745836","https://openalex.org/W1603175610","https://openalex.org/W1761316083","https://openalex.org/W1781555456","https://openalex.org/W1897711211","https://openalex.org/W1963847512","https://openalex.org/W1964342964","https://openalex.org/W1965158279","https://openalex.org/W1966190007","https://openalex.org/W1967306128","https://openalex.org/W1968001856","https://openalex.org/W1971821112","https://openalex.org/W1972763632","https://openalex.org/W1973374608","https://openalex.org/W1974256255","https://openalex.org/W1975704392","https://openalex.org/W1978245656","https://openalex.org/W1983292916","https://openalex.org/W1983592226","https://openalex.org/W1986279403","https://openalex.org/W1990557284","https://openalex.org/W1993051562","https://openalex.org/W1996348120","https://openalex.org/W1996909487","https://openalex.org/W1998007882","https://openalex.org/W2002197081","https://openalex.org/W2003079555","https://openalex.org/W2005144296","https://openalex.org/W2006530308","https://openalex.org/W2008327763","https://openalex.org/W2010035006","https://openalex.org/W2012545114","https://openalex.org/W2015310203","https://openalex.org/W2015333103","https://openalex.org/W2015512392","https://openalex.org/W2019684466","https://openalex.org/W2020460504","https://openalex.org/W2020789214","https://openalex.org/W2021930389","https://openalex.org/W2022401312","https://openalex.org/W2023057161","https://openalex.org/W2023896775","https://openalex.org/W2026074206","https://openalex.org/W2027794280","https://openalex.org/W2027984264","https://openalex.org/W2028527520","https://openalex.org/W2031110024","https://openalex.org/W2033771848","https://openalex.org/W2037557484","https://openalex.org/W2039515355","https://openalex.org/W2043675472","https://openalex.org/W2047925454","https://openalex.org/W2049551221","https://openalex.org/W2051547456","https://openalex.org/W2060593036","https://openalex.org/W2060640440","https://openalex.org/W2061869872","https://openalex.org/W2062522473","https://openalex.org/W2063499174","https://openalex.org/W2063633162","https://openalex.org/W2066785847","https://openalex.org/W2068694192","https://openalex.org/W2068891585","https://openalex.org/W2072763599","https://openalex.org/W2072909169","https://openalex.org/W2074514112","https://openalex.org/W2078140574","https://openalex.org/W2080624334","https://openalex.org/W2080788347","https://openalex.org/W2082147104","https://openalex.org/W2084437631","https://openalex.org/W2086398425","https://openalex.org/W2087191308","https://openalex.org/W2089169253","https://openalex.org/W2089632738","https://openalex.org/W2091561442","https://openalex.org/W2091925873","https://openalex.org/W2099545629","https://openalex.org/W2099637955","https://openalex.org/W2100818182","https://openalex.org/W2105681582","https://openalex.org/W2106102633","https://openalex.org/W2106411599","https://openalex.org/W2110999603","https://openalex.org/W2112653650","https://openalex.org/W2113004875","https://openalex.org/W2114326770","https://openalex.org/W2114501209","https://openalex.org/W2116486771","https://openalex.org/W2117246501","https://openalex.org/W2119180809","https://openalex.org/W2119238604","https://openalex.org/W2120035631","https://openalex.org/W2120705054","https://openalex.org/W2120731293","https://openalex.org/W2123341385","https://openalex.org/W2126189364","https://openalex.org/W2130631987","https://openalex.org/W2133684250","https://openalex.org/W2134024762","https://openalex.org/W2136132248","https://openalex.org/W2139321372","https://openalex.org/W2144853475","https://openalex.org/W2147352258","https://openalex.org/W2148532834","https://openalex.org/W2152292563","https://openalex.org/W2158341066","https://openalex.org/W2160488497","https://openalex.org/W2165403708","https://openalex.org/W2169363768","https://openalex.org/W2175175849","https://openalex.org/W2312244000","https://openalex.org/W3217490374"],"related_works":["https://openalex.org/W2123253863","https://openalex.org/W2051547456","https://openalex.org/W1969593265","https://openalex.org/W2105681582","https://openalex.org/W2412303236","https://openalex.org/W2019863129","https://openalex.org/W2800929874","https://openalex.org/W2076595502","https://openalex.org/W2027794280","https://openalex.org/W2593866219"],"abstract_inverted_index":{"Congenital":[0],"hypothyroidism":[1],"(CH),":[2],"a":[3,62],"pediatric":[4],"endocrine":[5],"condition":[6],"that":[7,89,148,207],"results":[8,87,211],"in":[9,37,75,171,212],"early":[10,45,190],"thyroid":[11],"hormone":[12],"(TH)":[13],"insufficiency,":[14],"is":[15,92,141,153,236],"associated":[16,93],"with":[17,79,82,94],"visuospatial":[18],"dysfunction":[19],"suggestive":[20],"of":[21,44,50,65,107,119,166,224],"selective":[22],"dorsal":[23,101,150,217,225],"visual":[24,30,73,151,169,218],"stream":[25,31,102,129,152,219,226,233],"impairment.":[26],"However,":[27],"the":[28,42,51,149,162,164,167,176,202,216,222],"ventral":[29,128,232],"has":[32],"not":[33,55],"been":[34,56],"adequately":[35],"investigated":[36],"this":[38,145,173],"population":[39],"and":[40,67,77,114,122,139,181,205,235],"so":[41],"effect":[43],"TH":[46,157,191,197,209],"insufficiency":[47,210],"on":[48,97,126],"development":[49,234],"two":[52],"streams":[53],"had":[54],"clearly":[57],"established.":[58],"This":[59],"thesis":[60,146,174],"used":[61],"comprehensive":[63],"set":[64],"neuropsychological":[66],"experimental":[68],"tests":[69],"to":[70,156,161,215,221,240],"assess":[71],"higher-order":[72,168],"functions":[74,103],"children":[76],"adolescents":[78],"CH":[80,91],"compared":[81],"typically":[83],"developing":[84],"individuals.":[85],"The":[86,199],"show":[88],"while":[90],"poorer":[95],"performance":[96,125],"tasks":[98,130],"tapping":[99],"into":[100],"such":[104,131],"as":[105,132],"judgment":[106,118],"line":[108],"orientation,":[109],"spatial":[110],"localization,":[111],"three-dimensional":[112],"block":[113],"two-dimensional":[115],"mental":[116,123],"construction,":[117],"object":[120],"location,":[121],"rotation,":[124],"typical":[127],"identity":[133],"discrimination,":[134],"including":[135],"abstract":[136],"shapes,":[137],"faces,":[138],"buildings,":[140],"relatively":[142],"unimpaired.":[143],"Thus":[144],"establishes":[147],"selectively":[154],"vulnerable":[155,239],"insufficiency.":[158],"In":[159],"addition":[160],"investigating":[163],"nature":[165],"problems":[170,180],"CH,":[172],"explores":[175],"mechanism":[177,204],"underlying":[178],"these":[179],"assesses":[182],"whether":[183],"they":[184],"result":[185],"from":[186],"organizational":[187,203],"effects":[188,194],"by":[189,195],"or":[192],"activational":[193],"current":[196],"levels.":[198],"data":[200],"support":[201],"suggest":[206],"prenatal":[208],"irreversible":[213],"changes":[214],"due":[220],"timing":[223],"development,":[227],"which":[228],"occurs":[229],"earlier":[230],"than":[231],"thus":[237],"more":[238],"insult.":[241]},"counts_by_year":[],"updated_date":"2026-10-01T08:54:57.152042","created_date":"2018-06-13T00:00:00"}