{"id":"https://openalex.org/W2805475105","doi":"https://doi.org/10.1039/c8nr03168a","title":"Nanopore based detection of Bacillus thuringiensis HD-73 spores using aptamers and versatile DNA hairpins","display_name":"Nanopore based detection of Bacillus thuringiensis HD-73 spores using aptamers and versatile DNA hairpins","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2805475105","doi":"https://doi.org/10.1039/c8nr03168a","mag":"2805475105","pmid":"https://pubmed.ncbi.nlm.nih.gov/29904756"},"language":"en","primary_location":{"id":"doi:10.1039/c8nr03168a","doi":"https://doi.org/10.1039/c8nr03168a","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c8nr03168a","pdf_url":null,"source":{"id":"https://openalex.org/S23181512","display_name":"Nanoscale","issn_l":"2040-3364","issn":["2040-3364","2040-3372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044235247","display_name":"Joongjin Park","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I191879574","display_name":"Inha University","ror":"https://ror.org/01easw929","country_code":"KR","type":"education","lineage":["https://openalex.org/I191879574"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Joongjin Park","raw_affiliation_strings":["Department of Biological Engineering","Incheon 22212","Inha University","Korea","WCSL of Integrated Human Airway-on-a-Chip","Department of Biological Engineering, Inha University, Incheon 22212, Korea","WCSL of Integrated Human Airway-on-a-Chip, Inha University, Incheon 22212, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Engineering","institution_ids":[]},{"raw_affiliation_string":"Incheon 22212","institution_ids":[]},{"raw_affiliation_string":"Inha University","institution_ids":["https://openalex.org/I191879574"]},{"raw_affiliation_string":"Korea","institution_ids":[]},{"raw_affiliation_string":"WCSL of Integrated Human Airway-on-a-Chip","institution_ids":[]},{"raw_affiliation_string":"Department of Biological Engineering, Inha University, Incheon 22212, Korea","institution_ids":["https://openalex.org/I191879574"]},{"raw_affiliation_string":"WCSL of Integrated Human Airway-on-a-Chip, Inha University, Incheon 22212, Korea","institution_ids":["https://openalex.org/I191879574"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101590695","display_name":"Min\u2010Cheol Lim","orcid":"https://orcid.org/0000-0002-1009-0316","observed_orcids":["https://orcid.org/0000-0002-1009-0316","https://orcid.org/0000-0002-9304-877X"]},"institutions":[{"id":"https://openalex.org/I35928602","display_name":"Kyung Hee University","ror":"https://ror.org/01zqcg218","country_code":"KR","type":"education","lineage":["https://openalex.org/I35928602"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Min-Cheol Lim","raw_affiliation_strings":["Institute of Life Sciences and Resources & Department of Food Science and Biotechnology","Korea","Kyung Hee University","Yongin 17104","Institute of Life Sciences and Resources & Department of Food Science and Biotechnology, Kyung Hee University, Yongin 17104, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Life Sciences and Resources & Department of Food Science and Biotechnology","institution_ids":[]},{"raw_affiliation_string":"Korea","institution_ids":[]},{"raw_affiliation_string":"Kyung Hee University","institution_ids":["https://openalex.org/I35928602"]},{"raw_affiliation_string":"Yongin 17104","institution_ids":[]},{"raw_affiliation_string":"Institute of Life Sciences and Resources & Department of Food Science and Biotechnology, Kyung Hee University, Yongin 17104, Korea","institution_ids":["https://openalex.org/I35928602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062206393","display_name":"Hyunil Ryu","orcid":"https://orcid.org/0000-0001-5691-6374","observed_orcids":["https://orcid.org/0000-0001-5691-6374"]},"institutions":[{"id":"https://openalex.org/I191879574","display_name":"Inha University","ror":"https://ror.org/01easw929","country_code":"KR","type":"education","lineage":["https://openalex.org/I191879574"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Hyunil Ryu","raw_affiliation_strings":["Department of Biological Engineering","Incheon 22212","Inha University","Korea","WCSL of Integrated Human Airway-on-a-Chip","Department of Biological Engineering, Inha University, Incheon 22212, Korea","WCSL of Integrated Human Airway-on-a-Chip, Inha University, Incheon 22212, Korea"],"raw_orcid":"https://orcid.org/0000-0001-5691-6374","affiliations":[{"raw_affiliation_string":"Department of Biological Engineering","institution_ids":[]},{"raw_affiliation_string":"Incheon 22212","institution_ids":[]},{"raw_affiliation_string":"Inha University","institution_ids":["https://openalex.org/I191879574"]},{"raw_affiliation_string":"Korea","institution_ids":[]},{"raw_affiliation_string":"WCSL of Integrated Human Airway-on-a-Chip","institution_ids":[]},{"raw_affiliation_string":"Department of Biological Engineering, Inha University, Incheon 22212, Korea","institution_ids":["https://openalex.org/I191879574"]},{"raw_affiliation_string":"WCSL of Integrated Human Airway-on-a-Chip, Inha University, Incheon 22212, Korea","institution_ids":["https://openalex.org/I191879574"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068580881","display_name":"Jiwook Shim","orcid":"https://orcid.org/0000-0003-4088-2557","observed_orcids":["https://orcid.org/0000-0003-4088-2557"]},"institutions":[{"id":"https://openalex.org/I44265643","display_name":"Rowan University","ror":"https://ror.org/049v69k10","country_code":"US","type":"education","lineage":["https://openalex.org/I44265643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jiwook Shim","raw_affiliation_strings":["Department of Biomedical Engineering","Glassboro","Rowan University","USA","Department of Biomedical Engineering, Rowan University, Glassboro, NJ 08028, USA"],"raw_orcid":"https://orcid.org/0000-0003-4088-2557","affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering","institution_ids":[]},{"raw_affiliation_string":"Glassboro","institution_ids":[]},{"raw_affiliation_string":"Rowan University","institution_ids":["https://openalex.org/I44265643"]},{"raw_affiliation_string":"USA","institution_ids":[]},{"raw_affiliation_string":"Department of Biomedical Engineering, Rowan University, Glassboro, NJ 08028, USA","institution_ids":["https://openalex.org/I44265643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100697189","display_name":"Sun Min Kim","orcid":"https://orcid.org/0000-0001-8420-637X","observed_orcids":["https://orcid.org/0000-0001-8420-637X"]},"institutions":[{"id":"https://openalex.org/I191879574","display_name":"Inha University","ror":"https://ror.org/01easw929","country_code":"KR","type":"education","lineage":["https://openalex.org/I191879574"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sun Min Kim","raw_affiliation_strings":["Department of Mechanical Engineering","Incheon 22212","Inha University","Korea","WCSL of Integrated Human Airway-on-a-Chip","Department of Mechanical Engineering, Inha University, Incheon 22212, Korea","WCSL of Integrated Human Airway-on-a-Chip, Inha University, Incheon 22212, Korea"],"raw_orcid":"https://orcid.org/0000-0001-8420-637X","affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering","institution_ids":[]},{"raw_affiliation_string":"Incheon 22212","institution_ids":[]},{"raw_affiliation_string":"Inha University","institution_ids":["https://openalex.org/I191879574"]},{"raw_affiliation_string":"Korea","institution_ids":[]},{"raw_affiliation_string":"WCSL of Integrated Human Airway-on-a-Chip","institution_ids":[]},{"raw_affiliation_string":"Department of Mechanical Engineering, Inha University, Incheon 22212, Korea","institution_ids":["https://openalex.org/I191879574"]},{"raw_affiliation_string":"WCSL of Integrated Human Airway-on-a-Chip, Inha University, Incheon 22212, Korea","institution_ids":["https://openalex.org/I191879574"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061936591","display_name":"Young\u2010Rok Kim","orcid":"https://orcid.org/0000-0001-6448-6079","observed_orcids":["https://orcid.org/0000-0001-6448-6079"]},"institutions":[{"id":"https://openalex.org/I35928602","display_name":"Kyung Hee University","ror":"https://ror.org/01zqcg218","country_code":"KR","type":"education","lineage":["https://openalex.org/I35928602"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Young-Rok Kim","raw_affiliation_strings":["Institute of Life Sciences and Resources & Department of Food Science and Biotechnology","Korea","Kyung Hee University","Yongin 17104","Institute of Life Sciences and Resources & Department of Food Science and Biotechnology, Kyung Hee University, Yongin 17104, Korea"],"raw_orcid":"https://orcid.org/0000-0001-6448-6079","affiliations":[{"raw_affiliation_string":"Institute of Life Sciences and Resources & Department of Food Science and Biotechnology","institution_ids":[]},{"raw_affiliation_string":"Korea","institution_ids":[]},{"raw_affiliation_string":"Kyung Hee University","institution_ids":["https://openalex.org/I35928602"]},{"raw_affiliation_string":"Yongin 17104","institution_ids":[]},{"raw_affiliation_string":"Institute of Life Sciences and Resources & Department of Food Science and Biotechnology, Kyung Hee University, Yongin 17104, Korea","institution_ids":["https://openalex.org/I35928602"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071852246","display_name":"Tae\u2010Joon Jeon","orcid":"https://orcid.org/0000-0002-4882-9040","observed_orcids":["https://orcid.org/0000-0002-4882-9040"]},"institutions":[{"id":"https://openalex.org/I191879574","display_name":"Inha University","ror":"https://ror.org/01easw929","country_code":"KR","type":"education","lineage":["https://openalex.org/I191879574"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Tae-Joon Jeon","raw_affiliation_strings":["Department of Biological Engineering","Incheon 22212","Inha University","Korea","WCSL of Integrated Human Airway-on-a-Chip","Department of Biological Engineering, Inha University, Incheon 22212, Korea","WCSL of Integrated Human Airway-on-a-Chip, Inha University, Incheon 22212, Korea"],"raw_orcid":"https://orcid.org/0000-0002-4882-9040","affiliations":[{"raw_affiliation_string":"Department of Biological Engineering","institution_ids":[]},{"raw_affiliation_string":"Incheon 22212","institution_ids":[]},{"raw_affiliation_string":"Inha University","institution_ids":["https://openalex.org/I191879574"]},{"raw_affiliation_string":"Korea","institution_ids":[]},{"raw_affiliation_string":"WCSL of Integrated Human Airway-on-a-Chip","institution_ids":[]},{"raw_affiliation_string":"Department of Biological Engineering, Inha University, Incheon 22212, Korea","institution_ids":["https://openalex.org/I191879574"]},{"raw_affiliation_string":"WCSL of Integrated Human Airway-on-a-Chip, Inha University, Incheon 22212, Korea","institution_ids":["https://openalex.org/I191879574"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5061936591","https://openalex.org/A5071852246"],"corresponding_institution_ids":["https://openalex.org/I191879574","https://openalex.org/I35928602"],"apc_list":null,"apc_paid":null,"fwci":0.7109,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.6405342,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"10","issue":"25","first_page":"11955","last_page":"11961"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11582","display_name":"Nanopore and Nanochannel Transport Studies","score":0.9340999722480774,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11582","display_name":"Nanopore and Nanochannel Transport Studies","score":0.9340999722480774,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.06270000338554382,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nanopore-sensing","display_name":"nanopore sensing","score":0.8809999823570251},{"id":"https://openalex.org/keywords/bacterial-spore-detection","display_name":"bacterial spore detection","score":0.925000011920929},{"id":"https://openalex.org/keywords/aptamers","display_name":"aptamers","score":0.9660000205039978},{"id":"https://openalex.org/keywords/dna-hairpin","display_name":"DNA hairpins","score":0.9919999837875366},{"id":"https://openalex.org/keywords/alpha-hemolysin-nanopore","display_name":"\u03b1-hemolysin nanopore","score":0.9599999785423279},{"id":"https://openalex.org/keywords/signal-to-noise-ratio-improvement","display_name":"signal-to-noise ratio improvement","score":0.6240000128746033},{"id":"https://openalex.org/keywords/sample-preparation","display_name":"sample preparation","score":0.5799999833106995},{"id":"https://openalex.org/keywords/detection-limit","display_name":"detection limit","score":0.6600000262260437}],"concepts":[{"id":"https://openalex.org/C2779035793","wikidata":"https://www.wikidata.org/wiki/Q310467","display_name":"Bacillus thuringiensis","level":3,"score":0.8541103601455688},{"id":"https://openalex.org/C128972844","wikidata":"https://www.wikidata.org/wiki/Q418722","display_name":"Aptamer","level":2,"score":0.694945752620697},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.6359535455703735},{"id":"https://openalex.org/C141795571","wikidata":"https://www.wikidata.org/wiki/Q580942","display_name":"Nanopore","level":2,"score":0.5598357915878296},{"id":"https://openalex.org/C174618031","wikidata":"https://www.wikidata.org/wiki/Q177332","display_name":"Spore","level":2,"score":0.5138369202613831},{"id":"https://openalex.org/C126513998","wikidata":"https://www.wikidata.org/wiki/Q8973627","display_name":"Nanopore sequencing","level":4,"score":0.4626399576663971},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.41940411925315857},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.38820233941078186},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.36184975504875183},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3370196223258972},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.32198798656463623},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.2850445806980133},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.2604583501815796},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.19434362649917603},{"id":"https://openalex.org/C51679486","wikidata":"https://www.wikidata.org/wiki/Q380546","display_name":"DNA sequencing","level":3,"score":0.18257451057434082},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.09025347232818604}],"mesh":[{"descriptor_ui":"D001413","descriptor_name":"Bacillus thuringiensis","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D052157","descriptor_name":"Aptamers, Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058608","descriptor_name":"Nanopores","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1039/c8nr03168a","doi":"https://doi.org/10.1039/c8nr03168a","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c8nr03168a","pdf_url":null,"source":{"id":"https://openalex.org/S23181512","display_name":"Nanoscale","issn_l":"2040-3364","issn":["2040-3364","2040-3372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"journal-article"},{"id":"pmid:29904756","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29904756","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3196758043","display_name":null,"funder_award_id":"NRF\u20102016R1A2B4006987","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G3273016217","display_name":null,"funder_award_id":"NRF-2017R1A2B4002523","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G8953288440","display_name":null,"funder_award_id":"NRF-2012-0009575","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"}],"funders":[{"id":"https://openalex.org/F4320321370","display_name":"Inha University","ror":"https://ror.org/01easw929"},{"id":"https://openalex.org/F4320322120","display_name":"National Research Foundation of Korea","ror":"https://ror.org/013aysd81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W1481296411","https://openalex.org/W1976397183","https://openalex.org/W1982309095","https://openalex.org/W1991440871","https://openalex.org/W2016687962","https://openalex.org/W2030302037","https://openalex.org/W2036221216","https://openalex.org/W2040866030","https://openalex.org/W2051632571","https://openalex.org/W2062415820","https://openalex.org/W2070813536","https://openalex.org/W2085381747","https://openalex.org/W2108058966","https://openalex.org/W2123498041","https://openalex.org/W2160448685","https://openalex.org/W2161427213","https://openalex.org/W2174892031","https://openalex.org/W2198839417","https://openalex.org/W2274936080","https://openalex.org/W2316313381","https://openalex.org/W2320205033","https://openalex.org/W2320267243","https://openalex.org/W2320910738","https://openalex.org/W2323849867","https://openalex.org/W2324683134","https://openalex.org/W2567274757","https://openalex.org/W2580457888","https://openalex.org/W2605347528","https://openalex.org/W2618761179","https://openalex.org/W2622222001","https://openalex.org/W2751330137","https://openalex.org/W2776393814","https://openalex.org/W2782996837","https://openalex.org/W2784577053","https://openalex.org/W2791581156","https://openalex.org/W2807505914"],"related_works":["https://openalex.org/W2788354988","https://openalex.org/W2732124355","https://openalex.org/W4302767843","https://openalex.org/W7170207990","https://openalex.org/W4281641788","https://openalex.org/W4417445566","https://openalex.org/W4412972829","https://openalex.org/W2515437324","https://openalex.org/W1997698671","https://openalex.org/W2312040641"],"abstract_inverted_index":{"A":[0],"versatile":[1],"nanopore":[2,44],"sensing":[3,76],"platform":[4,24,111],"to":[5,18,81,140,151],"detect":[6,26,69],"any":[7],"aptamer":[8,20,30],"using":[9,74,92],"nanopores":[10,94],"by":[11,53],"designing":[12],"DNA":[13,78,108],"hairpins":[14,79,89],"that":[15],"are":[16],"complementary":[17,80,107],"the":[19,27,48,57,61,82,88,96,106],"is":[21,51,148],"described.":[22],"This":[23],"can":[25],"presence":[28],"of":[29,34,56,98,131],"binding":[31],"targets":[32],"regardless":[33],"their":[35],"size,":[36],"which":[37],"has":[38],"been":[39],"a":[40,113,128],"major":[41],"hurdle":[42],"for":[43],"detection":[45,114],"systems.":[46],"Moreover,":[47],"signal-to-noise":[49],"ratio":[50],"increased":[52],"eliminating":[54],"most":[55],"unwanted":[58],"substances":[59],"from":[60,134],"sample":[62,65],"via":[63],"simple":[64],"preparation":[66],"steps.":[67],"To":[68],"Bacillus":[70],"thuringiensis":[71],"HD-73":[72],"spores":[73,99],"this":[75],"platform,":[77],"target-specific":[83],"aptamers":[84,101],"were":[85,90],"designed,":[86],"and":[87,100,102,124],"characterized":[91],"alpha-hemolysin":[93],"after":[95],"reaction":[97,104],"subsequent":[103],"with":[105,127],"hairpins.":[109],"The":[110],"exhibited":[112],"limit":[115],"as":[116,118],"low":[117],"1.2":[119,135,141],"\u00d7":[120,136,142],"101":[121,137],"CFU":[122,138,144],"mL-1":[123,139,145],"was":[125],"compatible":[126],"wide":[129],"range":[130],"spore":[132,153],"concentrations":[133],"106":[143],"while":[146],"it":[147],"still":[149],"expandable":[150],"higher":[152],"concentrations.":[154]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-06-13T00:00:00"}
