{"id":"https://openalex.org/W2805348592","doi":"https://doi.org/10.1200/jco.2018.36.15_suppl.513","title":"Factors associated with lymphedema in patients/women with node positive breast cancer treated with neoadjuvant chemotherapy and axillary dissection on a prospective clinical trial.","display_name":"Factors associated with lymphedema in patients/women with node positive breast cancer treated with neoadjuvant chemotherapy and axillary dissection on a prospective clinical trial.","publication_year":2018,"publication_date":"2018-05-20","ids":{"openalex":"https://openalex.org/W2805348592","doi":"https://doi.org/10.1200/jco.2018.36.15_suppl.513","mag":"2805348592"},"language":"en","primary_location":{"id":"doi:10.1200/jco.2018.36.15_suppl.513","doi":"https://doi.org/10.1200/jco.2018.36.15_suppl.513","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2018.36.15_suppl.513","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033544737","display_name":"Judy Caroline Boughey","orcid":"https://orcid.org/0000-0003-3820-3228","observed_orcids":["https://orcid.org/0000-0003-3820-3228"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Judy Caroline Boughey","raw_affiliation_strings":["Mayo Clinic, Rochester, MN;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic, Rochester, MN;","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074015095","display_name":"Karla V. Ballman","orcid":"https://orcid.org/0000-0002-4492-0357","observed_orcids":["https://orcid.org/0000-0002-4492-0357"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karla V. Ballman","raw_affiliation_strings":["Weill Cornell Medicine, New York, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Weill Cornell Medicine, New York, NY;","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053783063","display_name":"Linda Mackie McCall","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799844796","display_name":"Alliance for Clinical Trials in Oncology","ror":"https://ror.org/0009ha653","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2799844796"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Linda Mackie McCall","raw_affiliation_strings":["Alliance for Clinical Trials in Oncology, Durham, NC;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alliance for Clinical Trials in Oncology, Durham, NC;","institution_ids":["https://openalex.org/I2799844796"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084086867","display_name":"Henry M. Kuerer","orcid":"https://orcid.org/0000-0001-9108-768X","observed_orcids":["https://orcid.org/0000-0001-9108-768X"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Henry Mark Kuerer","raw_affiliation_strings":["The University of Texas MD Anderson Cancer Center, Houston, TX;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The University of Texas MD Anderson Cancer Center, Houston, TX;","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017411324","display_name":"Kelly K. Hunt","orcid":"https://orcid.org/0000-0001-9156-8723","observed_orcids":["https://orcid.org/0000-0001-9156-8723"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kelly Hunt","raw_affiliation_strings":["Department of Breast Surgical Oncology, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Breast Surgical Oncology, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX;","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031488531","display_name":"Jane M. Armer","orcid":"https://orcid.org/0000-0003-2473-5063","observed_orcids":["https://orcid.org/0000-0003-2473-5063"]},"institutions":[{"id":"https://openalex.org/I2800649613","display_name":"University of Missouri Health System","ror":"https://ror.org/03yp8z857","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800649613"]},{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jane M. Armer","raw_affiliation_strings":["University of Missouri Ellis Fischel Cancer Center, Columbia, MO;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Missouri Ellis Fischel Cancer Center, Columbia, MO;","institution_ids":["https://openalex.org/I2800649613","https://openalex.org/I76835614"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"36","issue":"15_suppl","first_page":"513","last_page":"513"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11469","display_name":"Lymphatic System and Diseases","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11469","display_name":"Lymphatic System and Diseases","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.03009999915957451,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10178","display_name":"Cancer survivorship and care","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lymphedema","display_name":"lymphedema","score":0.996999979019165},{"id":"https://openalex.org/keywords/node-positive-breast-cancer","display_name":"node-positive breast cancer","score":0.890999972820282},{"id":"https://openalex.org/keywords/neoadjuvant-chemotherapy","display_name":"neoadjuvant chemotherapy","score":0.9710000157356262},{"id":"https://openalex.org/keywords/axillary-lymph-node-dissection","display_name":"axillary lymph node dissection","score":0.9959999918937683},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.8130000233650208},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.9760000109672546},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.8040000200271606},{"id":"https://openalex.org/keywords/lymph-node-yield","display_name":"lymph node yield","score":0.4699999988079071},{"id":"https://openalex.org/keywords/adjuvant-radiotherapy","display_name":"adjuvant radiotherapy","score":0.8740000128746033},{"id":"https://openalex.org/keywords/breast-cancer-treatment-complications","display_name":"breast cancer treatment complications","score":0.6079999804496765}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9665215015411377},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.7627102136611938},{"id":"https://openalex.org/C2781392513","wikidata":"https://www.wikidata.org/wiki/Q916398","display_name":"Lymphedema","level":4,"score":0.6973279714584351},{"id":"https://openalex.org/C2908949552","wikidata":"https://www.wikidata.org/wiki/Q1809305","display_name":"Axillary Lymph Node Dissection","level":5,"score":0.6584217548370361},{"id":"https://openalex.org/C88879693","wikidata":"https://www.wikidata.org/wiki/Q217690","display_name":"Cumulative incidence","level":3,"score":0.5987175703048706},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5463200211524963},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.5113345980644226},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.5040687322616577},{"id":"https://openalex.org/C2781413609","wikidata":"https://www.wikidata.org/wiki/Q7308373","display_name":"Regimen","level":2,"score":0.47775617241859436},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.4739950895309448},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.41439518332481384},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3827640116214752},{"id":"https://openalex.org/C2780212769","wikidata":"https://www.wikidata.org/wiki/Q776290","display_name":"Sentinel lymph node","level":4,"score":0.12371531128883362},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.06967899203300476},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1200/jco.2018.36.15_suppl.513","doi":"https://doi.org/10.1200/jco.2018.36.15_suppl.513","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2018.36.15_suppl.513","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2956263224","https://openalex.org/W2072759723","https://openalex.org/W7097026002","https://openalex.org/W4237041974","https://openalex.org/W2835131620","https://openalex.org/W4382135529","https://openalex.org/W4403848460","https://openalex.org/W1997944980","https://openalex.org/W2991068431","https://openalex.org/W2090740650"],"abstract_inverted_index":{"513":[0],"Background:":[1],"Lymphedema":[2],"(LE)":[3],"is":[4],"a":[5,156],"known":[6],"complication":[7],"of":[8,39,62,91,102,125,136,162,170,176,184,187,221,254,273,279],"breast":[9,43,166,270],"cancer":[10],"treatment.":[11],"Herein":[12],"we":[13],"report":[14],"the":[15,29,50,131],"factors":[16],"associated":[17,181],"with":[18,41,182,203,218,232,264,276],"LE":[19,51,85,107,132,137,213,294],"after":[20,60,73,83],"neoadjuvant":[21,280],"chemotherapy":[22,163,281],"(NAC)":[23],"and":[24,57,64,70,80,174,200,237,252,266,282],"axillary":[25],"dissection":[26],"(ALND)":[27],"in":[28,36,191,201,230,285],"ACOSOG":[30],"Z1071":[31],"(Alliance":[32],"for":[33,152,258,268,293],"Clinical":[34,303],"Trials":[35],"Oncology)":[37],"trial":[38,304],"patients":[40,76,128,193,202,231,262],"node-positive":[42,78,269],"cancer.":[44],"Methods:":[45],"Patients":[46,284],"who":[47],"consented":[48,129],"to":[49,119,130,295],"substudy":[52],"underwent":[53,81],"prospective":[54],"arm":[55,92,99],"measurements":[56],"symptom":[58],"assessment":[59],"completion":[61],"NAC":[63,204,222,255,265],"at":[65,138],"6,":[66],"12,":[67],"18,":[68],"24,":[69],"36":[71],"months":[72],"surgery.":[74],"All":[75],"had":[77],"disease":[79],"ALND":[82,267],"NAC.":[84],"was":[86,108,141,189,215,228],"defined":[87,109],"based":[88],"on":[89],"symptoms":[90],"heaviness":[93],"or":[94,97],"swelling":[95],"(LE-symptoms)":[96],"by":[98,144,148],"volume":[100,111],"increase":[101,112],">":[103,113,195,206],"10%":[104],"(LE-V10);":[105],"severe":[106,153],"as":[110],"20%.":[114],"Kaplan-Meier":[115],"methods":[116],"were":[117,179,243],"used":[118],"determine":[120],"cumulative":[121],"incidence.":[122],"Results:":[123],"488":[124],"701":[126],"eligible":[127],"substudy.":[133],"Cumulative":[134],"incidence":[135,214,227],"3":[139],"years":[140],"37.8%":[142],"(33.0-43.1%)":[143],"LE-symptoms;":[145],"58.6%":[146],"(53.4-64.4%)":[147],"LE-V10;":[149],"37.2%":[150],"(32.2-42.9%)":[151],"LE.":[154,185],"In":[155,261],"univariable":[157],"analysis,":[158,250],"patient":[159],"age,":[160],"type":[161],"regimen":[164],"used,":[165],"surgical":[167],"procedure,":[168],"number":[169],"positive":[171],"lymph":[172,234,241],"nodes,":[173],"use":[175],"adjuvant":[177],"radiation":[178],"not":[180],"risk":[183,272],"Incidence":[186],"LE-symptoms":[188,274],"higher":[190,217],"obese":[192],"(BMI":[194],"30,":[196],"p":[197],"=":[198,210,224,246],"0.02)":[199],"duration":[205,220,278],"144":[207],"days":[208],"(p":[209,223,245],"0.029).":[211],"Severe":[212],"also":[216],"longer":[219,277],"0.01).":[225],"LE-V10":[226],"highest":[229],"30+":[233],"nodes":[235,242],"removed":[236,244],"lower":[238],"when":[239],"fewer":[240],"0.009).":[247],"On":[248],"multivariable":[249],"obesity":[251],"length":[253],"remained":[256],"significant":[257],"LE-symptoms.":[259],"Conclusions:":[260],"treated":[263],"cancer,":[271],"increases":[275],"obesity.":[283],"these":[286],"groups":[287],"may":[288],"benefit":[289],"from":[290],"closer":[291],"surveillance":[292],"allow":[296],"early":[297],"intervention.":[298],"Support:":[299],"U10CA180821,":[300],"U10CA180882,":[301],"UG1CA189823;":[302],"information:":[305],"NCT00881361.":[306]},"counts_by_year":[],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2018-06-13T00:00:00"}