{"id":"https://openalex.org/W2805203502","doi":"https://doi.org/10.1101/338277","title":"Parallel sexual and parasexual population genomic structure in Trypanosoma cruzi","display_name":"Parallel sexual and parasexual population genomic structure in Trypanosoma cruzi","publication_year":2018,"publication_date":"2018-06-04","ids":{"openalex":"https://openalex.org/W2805203502","doi":"https://doi.org/10.1101/338277","mag":"2805203502"},"language":"en","primary_location":{"id":"doi:10.1101/338277","doi":"https://doi.org/10.1101/338277","is_oa":true,"landing_page_url":"https://doi.org/10.1101/338277","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2018/06/04/338277.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nd","license_id":"https://openalex.org/licenses/cc-by-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.biorxiv.org/content/biorxiv/early/2018/06/04/338277.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070047803","display_name":"Philipp Schwabl","orcid":"https://orcid.org/0000-0002-1244-945X","observed_orcids":["https://orcid.org/0000-0002-1244-945X"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Philipp Schwabl","raw_affiliation_strings":["Institute of Biodiversity, Animal Health & Comparative Medicine, University of Glasgow","Institute of Biodiversity, Animal Health & Comparative Medicine, University of Glasgow, Glasgow G2 8QQ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biodiversity, Animal Health & Comparative Medicine, University of Glasgow","institution_ids":["https://openalex.org/I7882870"]},{"raw_affiliation_string":"Institute of Biodiversity, Animal Health & Comparative Medicine, University of Glasgow, Glasgow G2 8QQ, UK","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031739441","display_name":"Hideo Imamura","orcid":"https://orcid.org/0000-0002-3282-1319","observed_orcids":["https://orcid.org/0000-0002-3282-1319"]},"institutions":[{"id":"https://openalex.org/I78281549","display_name":"Instituut voor Tropische Geneeskunde","ror":"https://ror.org/03xq4x896","country_code":"BE","type":"funder","lineage":["https://openalex.org/I78281549"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Hideo Imamura","raw_affiliation_strings":["Unit of Molecular Parasitology, Institute of Tropical Medicine Antwerp","Unit of Molecular Parasitology, Institute of Tropical Medicine Antwerp, 155 Nationalestraat, 000, Antwerp, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit of Molecular Parasitology, Institute of Tropical Medicine Antwerp","institution_ids":["https://openalex.org/I78281549"]},{"raw_affiliation_string":"Unit of Molecular Parasitology, Institute of Tropical Medicine Antwerp, 155 Nationalestraat, 000, Antwerp, Belgium","institution_ids":["https://openalex.org/I78281549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008192364","display_name":"Frederik Van den Broeck","orcid":"https://orcid.org/0000-0003-2542-5585","observed_orcids":["https://orcid.org/0000-0003-2542-5585"]},"institutions":[{"id":"https://openalex.org/I78281549","display_name":"Instituut voor Tropische Geneeskunde","ror":"https://ror.org/03xq4x896","country_code":"BE","type":"funder","lineage":["https://openalex.org/I78281549"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Frederik Van den Broeck","raw_affiliation_strings":["Unit of Molecular Parasitology, Institute of Tropical Medicine Antwerp","Unit of Molecular Parasitology, Institute of Tropical Medicine Antwerp, 155 Nationalestraat, 000, Antwerp, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit of Molecular Parasitology, Institute of Tropical Medicine Antwerp","institution_ids":["https://openalex.org/I78281549"]},{"raw_affiliation_string":"Unit of Molecular Parasitology, Institute of Tropical Medicine Antwerp, 155 Nationalestraat, 000, Antwerp, Belgium","institution_ids":["https://openalex.org/I78281549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057047319","display_name":"Jaime Alfredo Costales","orcid":"https://orcid.org/0000-0001-9418-6640","observed_orcids":["https://orcid.org/0000-0001-9418-6640"]},"institutions":[{"id":"https://openalex.org/I39398033","display_name":"Pontificia Universidad Cat\u00f3lica del Ecuador","ror":"https://ror.org/02qztda51","country_code":"EC","type":"education","lineage":["https://openalex.org/I39398033"]}],"countries":["EC"],"is_corresponding":false,"raw_author_name":"Jaime A. Costales","raw_affiliation_strings":["Center for Research on Health in Latin America, School of Biological Sciences, Pontifical Catholic University of Ecuador","Center for Research on Health in Latin America, School of Biological Sciences, Pontifical Catholic University of Ecuador, Quito, Ecuador"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Research on Health in Latin America, School of Biological Sciences, Pontifical Catholic University of Ecuador","institution_ids":["https://openalex.org/I39398033"]},{"raw_affiliation_string":"Center for Research on Health in Latin America, School of Biological Sciences, Pontifical Catholic University of Ecuador, Quito, Ecuador","institution_ids":["https://openalex.org/I39398033"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003581754","display_name":"Jalil Maiguashca S\u00e1nchez","orcid":"https://orcid.org/0000-0001-8513-4064","observed_orcids":["https://orcid.org/0000-0001-8513-4064"]},"institutions":[{"id":"https://openalex.org/I39398033","display_name":"Pontificia Universidad Cat\u00f3lica del Ecuador","ror":"https://ror.org/02qztda51","country_code":"EC","type":"education","lineage":["https://openalex.org/I39398033"]}],"countries":["EC"],"is_corresponding":false,"raw_author_name":"Jalil Maiguashca","raw_affiliation_strings":["Center for Research on Health in Latin America, School of Biological Sciences, Pontifical Catholic University of Ecuador","Center for Research on Health in Latin America, School of Biological Sciences, Pontifical Catholic University of Ecuador, Quito, Ecuador"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Research on Health in Latin America, School of Biological Sciences, Pontifical Catholic University of Ecuador","institution_ids":["https://openalex.org/I39398033"]},{"raw_affiliation_string":"Center for Research on Health in Latin America, School of Biological Sciences, Pontifical Catholic University of Ecuador, Quito, Ecuador","institution_ids":["https://openalex.org/I39398033"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060778694","display_name":"Michael A. Miles","orcid":"https://orcid.org/0000-0002-5834-8734","observed_orcids":["https://orcid.org/0000-0002-5834-8734"]},"institutions":[{"id":"https://openalex.org/I4210089966","display_name":"London School of Hygiene & Tropical Medicine","ror":"https://ror.org/00a0jsq62","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210089966"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Michael A. Miles","raw_affiliation_strings":["London School of Hygiene & Tropical Medicine","London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"London School of Hygiene & Tropical Medicine","institution_ids":["https://openalex.org/I4210089966"]},{"raw_affiliation_string":"London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK","institution_ids":["https://openalex.org/I4210089966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006437281","display_name":"Bj\u00f6rn Andersson","orcid":"https://orcid.org/0000-0002-4624-0259","observed_orcids":["https://orcid.org/0000-0002-4624-0259"]},"institutions":[{"id":"https://openalex.org/I2800139495","display_name":"Science for Life Laboratory","ror":"https://ror.org/04ev03g22","country_code":"SE","type":"facility","lineage":["https://openalex.org/I2800139495"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Bjorn Andersson","raw_affiliation_strings":["Department of Cell and Molecular Biology, Science for Life Laboratory, Karolinska Institutet","Department of Cell and Molecular Biology, Science for Life Laboratory, Karolinska Institutet, Berzelius v\u00e4g 3, 171 77 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Molecular Biology, Science for Life Laboratory, Karolinska Institutet","institution_ids":["https://openalex.org/I2800139495","https://openalex.org/I28166907"]},{"raw_affiliation_string":"Department of Cell and Molecular Biology, Science for Life Laboratory, Karolinska Institutet, Berzelius v\u00e4g 3, 171 77 Stockholm, Sweden","institution_ids":["https://openalex.org/I2800139495","https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076005224","display_name":"Mario J. Grijalva","orcid":"https://orcid.org/0000-0003-1964-1425","observed_orcids":["https://orcid.org/0000-0003-1964-1425"]},"institutions":[{"id":"https://openalex.org/I39398033","display_name":"Pontificia Universidad Cat\u00f3lica del Ecuador","ror":"https://ror.org/02qztda51","country_code":"EC","type":"education","lineage":["https://openalex.org/I39398033"]},{"id":"https://openalex.org/I4210106879","display_name":"Ohio University","ror":"https://ror.org/01jr3y717","country_code":"US","type":"education","lineage":["https://openalex.org/I4210106879"]}],"countries":["EC","US"],"is_corresponding":false,"raw_author_name":"Mario J. Grijalva","raw_affiliation_strings":["Center for Research on Health in Latin America, School of Biological Sciences, Pontifical Catholic University of Ecuador","Infectious and Tropical Disease Institute, Biomedical Sciences Department, Heritage College of Osteopathic Medicine, Ohio University","Center for Research on Health in Latin America, School of Biological Sciences, Pontifical Catholic University of Ecuador, Quito, Ecuador","Infectious and Tropical Disease Institute, Biomedical Sciences Department, Heritage College of Osteopathic Medicine, Ohio University, 45701 Athens, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Research on Health in Latin America, School of Biological Sciences, Pontifical Catholic University of Ecuador","institution_ids":["https://openalex.org/I39398033"]},{"raw_affiliation_string":"Infectious and Tropical Disease Institute, Biomedical Sciences Department, Heritage College of Osteopathic Medicine, Ohio University","institution_ids":["https://openalex.org/I4210106879"]},{"raw_affiliation_string":"Center for Research on Health in Latin America, School of Biological Sciences, Pontifical Catholic University of Ecuador, Quito, Ecuador","institution_ids":["https://openalex.org/I39398033"]},{"raw_affiliation_string":"Infectious and Tropical Disease Institute, Biomedical Sciences Department, Heritage College of Osteopathic Medicine, Ohio University, 45701 Athens, OH, USA","institution_ids":["https://openalex.org/I4210106879"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057832799","display_name":"Martin Stephen Llewellyn","orcid":"https://orcid.org/0000-0001-9856-1591","observed_orcids":["https://orcid.org/0000-0001-9856-1591"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Martin S. Llewellyn","raw_affiliation_strings":["Institute of Biodiversity, Animal Health & Comparative Medicine, University of Glasgow","Institute of Biodiversity, Animal Health & Comparative Medicine, University of Glasgow, Glasgow G2 8QQ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biodiversity, Animal Health & Comparative Medicine, University of Glasgow","institution_ids":["https://openalex.org/I7882870"]},{"raw_affiliation_string":"Institute of Biodiversity, Animal Health & Comparative Medicine, University of Glasgow, Glasgow G2 8QQ, UK","institution_ids":["https://openalex.org/I7882870"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10890","display_name":"Trypanosoma species research and implications","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10890","display_name":"Trypanosoma species research and implications","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10012","display_name":"Genetic diversity and population structure","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/trypanosoma-cruzi","display_name":"Trypanosoma cruzi","score":1.0},{"id":"https://openalex.org/keywords/chagas-disease","display_name":"Chagas disease","score":0.8289999961853027},{"id":"https://openalex.org/keywords/sexual-reproduction","display_name":"sexual reproduction","score":0.7089999914169312},{"id":"https://openalex.org/keywords/metapopulation-structure","display_name":"metapopulation structure","score":0.8230000138282776},{"id":"https://openalex.org/keywords/genetic-exchange","display_name":"genetic exchange","score":0.6610000133514404},{"id":"https://openalex.org/keywords/aneuploidy","display_name":"aneuploidy","score":0.8069999814033508},{"id":"https://openalex.org/keywords/trisomy","display_name":"trisomy","score":0.8659999966621399},{"id":"https://openalex.org/keywords/gene-flow","display_name":"gene flow","score":0.6010000109672546},{"id":"https://openalex.org/keywords/population-genomics","display_name":"population genomics","score":0.4309999942779541},{"id":"https://openalex.org/keywords/reproductive-mode","display_name":"reproductive mode","score":0.3709999918937683},{"id":"https://openalex.org/keywords/southern-ecuador","display_name":"southern Ecuador","score":0.6050000190734863}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8753542900085449},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.688094973564148},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.5183345079421997},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4884018301963806},{"id":"https://openalex.org/C54809848","wikidata":"https://www.wikidata.org/wiki/Q1918189","display_name":"Meiotic drive","level":4,"score":0.46447575092315674},{"id":"https://openalex.org/C175783326","wikidata":"https://www.wikidata.org/wiki/Q185055","display_name":"Mendelian inheritance","level":3,"score":0.4597613215446472},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4354900121688843},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.2989504933357239},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.18805590271949768},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1101/338277","doi":"https://doi.org/10.1101/338277","is_oa":true,"landing_page_url":"https://doi.org/10.1101/338277","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2018/06/04/338277.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nd","license_id":"https://openalex.org/licenses/cc-by-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1101/338277","doi":"https://doi.org/10.1101/338277","is_oa":true,"landing_page_url":"https://doi.org/10.1101/338277","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2018/06/04/338277.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nd","license_id":"https://openalex.org/licenses/cc-by-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.4000000059604645,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2373809948","display_name":"Characterization of Trypanosoma cruzi in southern Ecuador","funder_award_id":"R15AI077896","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G4445801822","display_name":"Landscape genetics guide NTD interventions: Chagas disease in Ecuador and Peru","funder_award_id":"1r15ai105749-01a1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G551931138","display_name":null,"funder_award_id":"K13063","funder_id":"https://openalex.org/F4320327255","funder_display_name":"Pontificia Universidad Cat\u00f3lica del Ecuador"},{"id":"https://openalex.org/G5741074619","display_name":null,"funder_award_id":"I13048, J13033, K13063 and L13225","funder_id":"https://openalex.org/F4320327255","funder_display_name":"Pontificia Universidad Cat\u00f3lica del Ecuador"},{"id":"https://openalex.org/G5839465387","display_name":"Regional Training Center for Tropical Disease Research in Quito-Ecuador","funder_award_id":"D43TW008261","funder_id":"https://openalex.org/F4320337356","funder_display_name":"Fogarty International Center"},{"id":"https://openalex.org/G6232290138","display_name":null,"funder_award_id":"L13225","funder_id":"https://openalex.org/F4320327255","funder_display_name":"Pontificia Universidad Cat\u00f3lica del Ecuador"},{"id":"https://openalex.org/G6545643287","display_name":null,"funder_award_id":"AI077896-01","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G8057911401","display_name":null,"funder_award_id":"AI105749-01A1","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G8914172189","display_name":null,"funder_award_id":"TW008261","funder_id":"https://openalex.org/F4320337356","funder_display_name":"Fogarty International Center"}],"funders":[{"id":"https://openalex.org/F4320327255","display_name":"Pontificia Universidad Cat\u00f3lica del Ecuador","ror":"https://ror.org/02qztda51"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337356","display_name":"Fogarty International Center","ror":"https://ror.org/02xey9a22"},{"id":"https://openalex.org/F4320338412","display_name":"Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2805203502.pdf","grobid_xml":"https://content.openalex.org/works/W2805203502.grobid-xml"},"referenced_works_count":96,"referenced_works":["https://openalex.org/W913218581","https://openalex.org/W986136330","https://openalex.org/W1514141172","https://openalex.org/W1525465470","https://openalex.org/W1565378970","https://openalex.org/W1766675874","https://openalex.org/W1847830077","https://openalex.org/W1892029173","https://openalex.org/W1933020409","https://openalex.org/W1953078440","https://openalex.org/W1956202131","https://openalex.org/W1962960380","https://openalex.org/W1966413892","https://openalex.org/W1976678294","https://openalex.org/W1977601452","https://openalex.org/W1979692840","https://openalex.org/W1980782592","https://openalex.org/W1989617608","https://openalex.org/W1990275569","https://openalex.org/W1991998643","https://openalex.org/W1993106168","https://openalex.org/W1997195270","https://openalex.org/W2001603620","https://openalex.org/W2003262161","https://openalex.org/W2006273398","https://openalex.org/W2016381774","https://openalex.org/W2016833615","https://openalex.org/W2017634498","https://openalex.org/W2018742603","https://openalex.org/W2031557596","https://openalex.org/W2038564352","https://openalex.org/W2039579163","https://openalex.org/W2043313802","https://openalex.org/W2044388526","https://openalex.org/W2049351935","https://openalex.org/W2051650406","https://openalex.org/W2055298722","https://openalex.org/W2056864334","https://openalex.org/W2059134652","https://openalex.org/W2059980913","https://openalex.org/W2075601569","https://openalex.org/W2080873675","https://openalex.org/W2087322674","https://openalex.org/W2090085993","https://openalex.org/W2092296116","https://openalex.org/W2093236649","https://openalex.org/W2095101507","https://openalex.org/W2097374545","https://openalex.org/W2100357845","https://openalex.org/W2102359024","https://openalex.org/W2106578986","https://openalex.org/W2107864580","https://openalex.org/W2111534865","https://openalex.org/W2112338833","https://openalex.org/W2114769469","https://openalex.org/W2118361627","https://openalex.org/W2122402452","https://openalex.org/W2122689804","https://openalex.org/W2132325365","https://openalex.org/W2135769664","https://openalex.org/W2138345444","https://openalex.org/W2138619057","https://openalex.org/W2139466774","https://openalex.org/W2140784970","https://openalex.org/W2141694372","https://openalex.org/W2147830249","https://openalex.org/W2148299087","https://openalex.org/W2149992227","https://openalex.org/W2151409320","https://openalex.org/W2161640068","https://openalex.org/W2163432338","https://openalex.org/W2163681826","https://openalex.org/W2164418313","https://openalex.org/W2165725065","https://openalex.org/W2168133698","https://openalex.org/W2168458479","https://openalex.org/W2211498717","https://openalex.org/W2212569455","https://openalex.org/W2230276206","https://openalex.org/W2268038961","https://openalex.org/W2287087292","https://openalex.org/W2297979832","https://openalex.org/W2299589298","https://openalex.org/W2311753124","https://openalex.org/W2319074417","https://openalex.org/W2408926255","https://openalex.org/W2507746744","https://openalex.org/W2519651118","https://openalex.org/W2582923994","https://openalex.org/W2739743802","https://openalex.org/W2795872100","https://openalex.org/W3134317746","https://openalex.org/W4210980497","https://openalex.org/W4210992500","https://openalex.org/W4251304755","https://openalex.org/W4299711483"],"related_works":["https://openalex.org/W2972296854","https://openalex.org/W913218581","https://openalex.org/W2946092681","https://openalex.org/W1973337536","https://openalex.org/W2013977127","https://openalex.org/W7096536210","https://openalex.org/W4229444703","https://openalex.org/W1946696519","https://openalex.org/W1979692840","https://openalex.org/W2030897589"],"abstract_inverted_index":{"Abstract":[0],"Genetic":[1],"exchange":[2,41],"and":[3,16,53,123,146,175,180,208,220,229],"hybridization":[4],"in":[5,42,85,158,193,206],"parasitic":[6],"organisms":[7],"is":[8,68],"fundamental":[9],"to":[10],"the":[11,46,200,215,222],"exploitation":[12],"of":[13,58,81,112,148,171,225],"new":[14],"hosts":[15],"host":[17],"populations.":[18],"Variable":[19],"mating":[20],"frequency":[21],"often":[22],"coincides":[23],"with":[24,128,151],"strong":[25],"metapopulation":[26],"structure,":[27],"where":[28],"patchy":[29],"selection":[30],"or":[31],"demography":[32],"may":[33],"favor":[34],"different":[35],"reproductive":[36,56,227],"modes.":[37],"Evidence":[38],"for":[39,214,233],"genetic":[40,177],"Trypanosoma":[43],"cruzi":[44,83,98],"over":[45],"last":[47],"30":[48],"years":[49],"has":[50],"been":[51],"limited":[52],"inconclusive.":[54],"The":[55],"modes":[57,228],"other":[59],"medically":[60,235],"important":[61,236],"trypanosomatids":[62],"are":[63],"better":[64],"established,":[65],"although":[66],"little":[67],"known":[69],"about":[70],"their":[71,230],"variability":[72],"on":[73],"a":[74,78,190],"spatio-temporal":[75],"scale.":[76],"Targeting":[77],"contemporary":[79],"focus":[80],"T.":[82,97],"transmission":[84],"southern":[86],"Ecuador,":[87],"we":[88,218],"present":[89,165],"compelling":[90],"evidence":[91],"from":[92,116,133],"45":[93],"sequenced":[94],"genomes":[95],"that":[96,108,202],"(discrete":[99],"typing":[100],"unit":[101],"I)":[102],"maintains":[103],"sexual":[104],"populations":[105],"alongside":[106],"others":[107],"represent":[109],"clonal":[110],"bursts":[111],"parasexual":[113,176],"origin.":[114],"Strains":[115,131],"one":[117],"site":[118],"exhibit":[119,156],"genome-wide":[120],"Hardy-Weinberg":[121],"equilibrium":[122],"intra-chromosomal":[124],"linkage":[125],"decay":[126],"consistent":[127],"meiotic":[129],"reproduction.":[130],"collected":[132],"adjacent":[134],"areas":[135],"(>6":[136],"km)":[137],"show":[138],"excess":[139],"heterozygosity,":[140],"near-identical":[141],"haplo-segments,":[142],"common":[143],"mitochondrial":[144],"sequences":[145],"levels":[147],"aneuploidy":[149],"incompatible":[150],"Mendelian":[152],"sex.":[153],"Certain":[154],"individuals":[155],"trisomy":[157],"as":[159,161,183,185],"many":[160],"fifteen":[162],"chromosomes.":[163],"Others":[164],"fewer,":[166],"yet":[167],"shared,":[168],"aneuploidies":[169],"reminiscent":[170],"mitotic":[172],"genome":[173],"erosion":[174],"exchange.":[178],"Genomic":[179],"intra-genomic":[181],"phylogenetics":[182],"well":[184],"haplotype":[186],"co-ancestry":[187],"analyses":[188],"indicate":[189],"clear":[191],"break":[192],"gene-flow":[194],"between":[195],"these":[196],"distinct":[197],"populations,":[198],"despite":[199],"fact":[201],"they":[203],"occasionally":[204],"co-occur":[205],"vectors":[207],"hosts.":[209],"We":[210],"propose":[211],"biological":[212],"explanations":[213],"fine-scale":[216],"disconnectivity":[217],"observe":[219],"discuss":[221],"epidemiological":[223],"consequences":[224],"flexible":[226],"genomic":[231],"architecture":[232],"this":[234],"parasite.":[237]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-06-13T00:00:00"}
