{"id":"https://openalex.org/W2804896819","doi":"https://doi.org/10.1186/s12885-018-4243-7","title":"Ezrin and E-cadherin expression profile in cervical cytology: a prognostic marker for tumor progression in cervical cancer","display_name":"Ezrin and E-cadherin expression profile in cervical cytology: a prognostic marker for tumor progression in cervical cancer","publication_year":2018,"publication_date":"2018-03-27","ids":{"openalex":"https://openalex.org/W2804896819","doi":"https://doi.org/10.1186/s12885-018-4243-7","mag":"2804896819","pmid":"https://pubmed.ncbi.nlm.nih.gov/29587669","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5872531"},"language":"en","primary_location":{"id":"doi:10.1186/s12885-018-4243-7","doi":"https://doi.org/10.1186/s12885-018-4243-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12885-018-4243-7","pdf_url":"https://bmccancer.biomedcentral.com/track/pdf/10.1186/s12885-018-4243-7","source":{"id":"https://openalex.org/S192926780","display_name":"BMC Cancer","issn_l":"1471-2407","issn":["1471-2407"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Cancer","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmccancer.biomedcentral.com/track/pdf/10.1186/s12885-018-4243-7","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102864175","display_name":"Ana Elvira Zacapala-G\u00f3mez","orcid":"https://orcid.org/0000-0003-4935-6094","observed_orcids":["https://orcid.org/0000-0003-4935-6094"]},"institutions":[{"id":"https://openalex.org/I3130105584","display_name":"Universidad Aut\u00f3noma de Guerrero","ror":"https://ror.org/054tbkd46","country_code":"MX","type":"education","lineage":["https://openalex.org/I3130105584"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Ana E. Zacapala-G\u00f3mez","raw_affiliation_strings":["Laboratorio de Biomedicina Molecular, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Guerrero, Av. Lazaro Cardenas s/n, Ciudad Universitaria, CP, 39090, Chilpancingo, Guerrero, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio de Biomedicina Molecular, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Guerrero, Av. Lazaro Cardenas s/n, Ciudad Universitaria, CP, 39090, Chilpancingo, Guerrero, Mexico","institution_ids":["https://openalex.org/I3130105584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034167396","display_name":"Napole\u00f3n Navarro\u2010Tito","orcid":"https://orcid.org/0000-0003-4911-0545","observed_orcids":["https://orcid.org/0000-0003-4911-0545"]},"institutions":[{"id":"https://openalex.org/I3130105584","display_name":"Universidad Aut\u00f3noma de Guerrero","ror":"https://ror.org/054tbkd46","country_code":"MX","type":"education","lineage":["https://openalex.org/I3130105584"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Napole\u00f3n Navarro-Tito","raw_affiliation_strings":["Laboratorio de Biolog\u00eda Celular del C\u00e1ncer, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Guerrero, Chilpancingo, Guerrero, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio de Biolog\u00eda Celular del C\u00e1ncer, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Guerrero, Chilpancingo, Guerrero, Mexico","institution_ids":["https://openalex.org/I3130105584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038185040","display_name":"Luz del Carmen Alarc\u00f3n\u2010Romero","orcid":"https://orcid.org/0000-0002-2074-4889","observed_orcids":["https://orcid.org/0000-0002-2074-4889"]},"institutions":[{"id":"https://openalex.org/I3130105584","display_name":"Universidad Aut\u00f3noma de Guerrero","ror":"https://ror.org/054tbkd46","country_code":"MX","type":"education","lineage":["https://openalex.org/I3130105584"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Luz del C. Alarc\u00f3n-Romero","raw_affiliation_strings":["Laboratorio de Citopatolog\u00eda e Histoqu\u00edmica, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Guerrero, Chilpancingo, Guerrero, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio de Citopatolog\u00eda e Histoqu\u00edmica, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Guerrero, Chilpancingo, Guerrero, Mexico","institution_ids":["https://openalex.org/I3130105584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026062684","display_name":"Carlos Ortu\u00f1o\u2010Pineda","orcid":"https://orcid.org/0000-0002-1757-1964","observed_orcids":["https://orcid.org/0000-0002-1757-1964","https://orcid.org/0000-0002-9980-7212"]},"institutions":[{"id":"https://openalex.org/I3130105584","display_name":"Universidad Aut\u00f3noma de Guerrero","ror":"https://ror.org/054tbkd46","country_code":"MX","type":"education","lineage":["https://openalex.org/I3130105584"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Carlos Ortu\u00f1o-Pineda","raw_affiliation_strings":["Laboratorio de \u00c1cidos nucleicos y prote\u00ednas, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Guerrero, Chilpancingo, Guerrero, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio de \u00c1cidos nucleicos y prote\u00ednas, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Guerrero, Chilpancingo, Guerrero, Mexico","institution_ids":["https://openalex.org/I3130105584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060673264","display_name":"Berenice Illades\u2010Aguiar","orcid":"https://orcid.org/0000-0003-3937-335X","observed_orcids":["https://orcid.org/0000-0003-3937-335X"]},"institutions":[{"id":"https://openalex.org/I3130105584","display_name":"Universidad Aut\u00f3noma de Guerrero","ror":"https://ror.org/054tbkd46","country_code":"MX","type":"education","lineage":["https://openalex.org/I3130105584"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Berenice Illades-Aguiar","raw_affiliation_strings":["Laboratorio de Biomedicina Molecular, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Guerrero, Av. Lazaro Cardenas s/n, Ciudad Universitaria, CP, 39090, Chilpancingo, Guerrero, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio de Biomedicina Molecular, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Guerrero, Av. Lazaro Cardenas s/n, Ciudad Universitaria, CP, 39090, Chilpancingo, Guerrero, Mexico","institution_ids":["https://openalex.org/I3130105584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040659829","display_name":"Eduardo Casta\u00f1eda-Saucedo","orcid":"https://orcid.org/0000-0002-0669-4408","observed_orcids":["https://orcid.org/0000-0002-0669-4408","https://orcid.org/0009-0002-2013-8755"]},"institutions":[{"id":"https://openalex.org/I3130105584","display_name":"Universidad Aut\u00f3noma de Guerrero","ror":"https://ror.org/054tbkd46","country_code":"MX","type":"education","lineage":["https://openalex.org/I3130105584"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Eduardo Casta\u00f1eda-Saucedo","raw_affiliation_strings":["Laboratorio de Biolog\u00eda Celular del C\u00e1ncer, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Guerrero, Chilpancingo, Guerrero, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio de Biolog\u00eda Celular del C\u00e1ncer, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Guerrero, Chilpancingo, Guerrero, Mexico","institution_ids":["https://openalex.org/I3130105584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002594379","display_name":"Julio Ortiz\u2010Ortiz","orcid":"https://orcid.org/0000-0003-3082-4716","observed_orcids":["https://orcid.org/0000-0003-3082-4716"]},"institutions":[{"id":"https://openalex.org/I3130105584","display_name":"Universidad Aut\u00f3noma de Guerrero","ror":"https://ror.org/054tbkd46","country_code":"MX","type":"education","lineage":["https://openalex.org/I3130105584"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Julio Ortiz-Ortiz","raw_affiliation_strings":["Laboratorio de Biomedicina Molecular, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Guerrero, Av. Lazaro Cardenas s/n, Ciudad Universitaria, CP, 39090, Chilpancingo, Guerrero, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio de Biomedicina Molecular, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Guerrero, Av. Lazaro Cardenas s/n, Ciudad Universitaria, CP, 39090, Chilpancingo, Guerrero, Mexico","institution_ids":["https://openalex.org/I3130105584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031434741","display_name":"Olga Lilia Garibay\u2010Cerdenares","orcid":"https://orcid.org/0000-0002-0986-9453","observed_orcids":["https://orcid.org/0000-0002-0986-9453"]},"institutions":[{"id":"https://openalex.org/I3130105584","display_name":"Universidad Aut\u00f3noma de Guerrero","ror":"https://ror.org/054tbkd46","country_code":"MX","type":"education","lineage":["https://openalex.org/I3130105584"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Olga L. Garibay-Cerdenares","raw_affiliation_strings":["Laboratorio de Biomedicina Molecular, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Guerrero, Av. Lazaro Cardenas s/n, Ciudad Universitaria, CP, 39090, Chilpancingo, Guerrero, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio de Biomedicina Molecular, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Guerrero, Av. Lazaro Cardenas s/n, Ciudad Universitaria, CP, 39090, Chilpancingo, Guerrero, Mexico","institution_ids":["https://openalex.org/I3130105584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091038498","display_name":"Marco Antonio Jim\u00e9nez-L\u00f3pez","orcid":"https://orcid.org/0009-0008-0088-1801","observed_orcids":["https://orcid.org/0009-0008-0088-1801","https://orcid.org/0000-0002-9712-9577"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marco A. Jim\u00e9nez-L\u00f3pez","raw_affiliation_strings":["Instituto Estatal de Cancerolog\u00eda, Acapulco, Guerrero, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto Estatal de Cancerolog\u00eda, Acapulco, Guerrero, Mexico","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047660851","display_name":"Miguel Angel Mendoza Catal\u00e1n","orcid":"https://orcid.org/0000-0002-6247-8590","observed_orcids":["https://orcid.org/0000-0002-6247-8590"]},"institutions":[{"id":"https://openalex.org/I3130105584","display_name":"Universidad Aut\u00f3noma de Guerrero","ror":"https://ror.org/054tbkd46","country_code":"MX","type":"education","lineage":["https://openalex.org/I3130105584"]}],"countries":["MX"],"is_corresponding":true,"raw_author_name":"Miguel A. Mendoza-Catal\u00e1n","raw_affiliation_strings":["Laboratorio de Biomedicina Molecular, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Guerrero, Av. Lazaro Cardenas s/n, Ciudad Universitaria, CP, 39090, Chilpancingo, Guerrero, Mexico. mamendoza@uagro.mx","Laboratorio de Biomedicina Molecular, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Guerrero, Av. Lazaro Cardenas s/n, Ciudad Universitaria, CP, 39090, Chilpancingo, Guerrero, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio de Biomedicina Molecular, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Guerrero, Av. Lazaro Cardenas s/n, Ciudad Universitaria, CP, 39090, Chilpancingo, Guerrero, Mexico. mamendoza@uagro.mx","institution_ids":["https://openalex.org/I3130105584"]},{"raw_affiliation_string":"Laboratorio de Biomedicina Molecular, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Guerrero, Av. Lazaro Cardenas s/n, Ciudad Universitaria, CP, 39090, Chilpancingo, Guerrero, Mexico","institution_ids":["https://openalex.org/I3130105584"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5047660851"],"corresponding_institution_ids":["https://openalex.org/I3130105584"],"apc_list":{"value":3390,"currency":"USD","value_usd":3390},"apc_paid":{"value":3390,"currency":"USD","value_usd":3390},"fwci":3.564,"has_fulltext":true,"cited_by_count":30,"citation_normalized_percentile":{"value":0.93159371,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"18","issue":"1","first_page":"349","last_page":"349"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10668","display_name":"Endometrial and Cervical Cancer Treatments","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ezrin","display_name":"ezrin","score":0.9620000123977661},{"id":"https://openalex.org/keywords/e-cadherin","display_name":"E-cadherin","score":1.0},{"id":"https://openalex.org/keywords/cervical-cancer","display_name":"cervical cancer","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cervical-intraepithelial-neoplasia","display_name":"cervical intraepithelial neoplasia","score":0.890999972820282},{"id":"https://openalex.org/keywords/liquid-based-cytology","display_name":"liquid-based cytology","score":0.7459999918937683},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.8930000066757202},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.7400000095367432},{"id":"https://openalex.org/keywords/high-risk-hpv","display_name":"high-risk HPV","score":0.6439999938011169},{"id":"https://openalex.org/keywords/hpv-genotyping","display_name":"HPV genotyping","score":0.6919999718666077},{"id":"https://openalex.org/keywords/viral-integration","display_name":"viral integration","score":0.765999972820282},{"id":"https://openalex.org/keywords/immunomarkers","display_name":"immunomarkers","score":0.5860000252723694}],"concepts":[{"id":"https://openalex.org/C2780246058","wikidata":"https://www.wikidata.org/wiki/Q18032329","display_name":"Ezrin","level":4,"score":0.9439994096755981},{"id":"https://openalex.org/C2778220009","wikidata":"https://www.wikidata.org/wiki/Q160105","display_name":"Cervical cancer","level":3,"score":0.6329607963562012},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.44287556409835815},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.43019387125968933},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4238939583301544},{"id":"https://openalex.org/C2777343196","wikidata":"https://www.wikidata.org/wiki/Q196788","display_name":"Cervical intraepithelial neoplasia","level":4,"score":0.4141952395439148},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3770103454589844},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33320313692092896},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1579032838344574},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.11822628974914551},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C142669718","wikidata":"https://www.wikidata.org/wiki/Q154626","display_name":"Cytoskeleton","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000099149","descriptor_name":"Ezrin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D003598","descriptor_name":"Cytoskeletal Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003598","descriptor_name":"Cytoskeletal Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015820","descriptor_name":"Cadherins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015820","descriptor_name":"Cadherins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021381","descriptor_name":"Protein Transport","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D027383","descriptor_name":"Papillomaviridae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12885-018-4243-7","doi":"https://doi.org/10.1186/s12885-018-4243-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12885-018-4243-7","pdf_url":"https://bmccancer.biomedcentral.com/track/pdf/10.1186/s12885-018-4243-7","source":{"id":"https://openalex.org/S192926780","display_name":"BMC Cancer","issn_l":"1471-2407","issn":["1471-2407"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Cancer","raw_type":"journal-article"},{"id":"pmid:29587669","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29587669","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC cancer","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5872531","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5872531/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Cancer","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:2243ef664c9d4945a1f46db6d607ecd4","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/2243ef664c9d4945a1f46db6d607ecd4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12885-018-4243-7","doi":"https://doi.org/10.1186/s12885-018-4243-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12885-018-4243-7","pdf_url":"https://bmccancer.biomedcentral.com/track/pdf/10.1186/s12885-018-4243-7","source":{"id":"https://openalex.org/S192926780","display_name":"BMC Cancer","issn_l":"1471-2407","issn":["1471-2407"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Cancer","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320311777","display_name":"Secretar\u00eda de Educaci\u00f3n P\u00fablica","ror":"https://ror.org/02e1c4h55"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2804896819.pdf","grobid_xml":"https://content.openalex.org/works/W2804896819.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W1757407923","https://openalex.org/W1896095957","https://openalex.org/W1991557225","https://openalex.org/W2016245532","https://openalex.org/W2016688101","https://openalex.org/W2033722837","https://openalex.org/W2035242360","https://openalex.org/W2045739383","https://openalex.org/W2051834728","https://openalex.org/W2066064555","https://openalex.org/W2066819304","https://openalex.org/W2075186063","https://openalex.org/W2084319729","https://openalex.org/W2085283758","https://openalex.org/W2100473445","https://openalex.org/W2129939002","https://openalex.org/W2142881721","https://openalex.org/W2147048296","https://openalex.org/W2263035688","https://openalex.org/W2290561567","https://openalex.org/W2345599686","https://openalex.org/W2399512369","https://openalex.org/W2438624851","https://openalex.org/W2463587629","https://openalex.org/W2517055328","https://openalex.org/W2525234831","https://openalex.org/W2549491910","https://openalex.org/W2590767416","https://openalex.org/W2601887934","https://openalex.org/W2624803069","https://openalex.org/W2626237582","https://openalex.org/W2731397105","https://openalex.org/W4210995086"],"related_works":["https://openalex.org/W2129939002","https://openalex.org/W2898416679","https://openalex.org/W3195629648","https://openalex.org/W1970641013","https://openalex.org/W2005651052","https://openalex.org/W7109465074","https://openalex.org/W2361577899","https://openalex.org/W2069099757","https://openalex.org/W3087035219","https://openalex.org/W2386101153"],"abstract_inverted_index":{"BACKGROUND:":[0],"Cervical":[1],"cancer":[2,146,186],"(CC)":[3],"is":[4,19],"the":[5,113],"fourth":[6],"cause":[7],"of":[8,17,30,36,41,77,86,170,208,221,231,273],"mortality":[9],"by":[10,96,117,132,153,193],"neoplasia":[11],"in":[12,49,61,83,118,123,144,184,255],"women":[13],"worldwide.":[14],"The":[15,89],"use":[16,70],"immunomarkers":[18],"an":[20,46],"alternative":[21],"tool":[22],"to":[23,33,244,275],"complement":[24],"currently":[25],"used":[26],"algorithms":[27],"for":[28,242,266],"detection":[29],"cancer,":[31],"and":[32,43,58,66,79,112,126,135,156,174,196,210,223,234,246,251],"improve":[34],"selection":[35],"therapeutic":[37],"schemes.":[38],"Aberrant":[39],"expression":[40,60,122,141,165,181,203,237,253],"Ezrin":[42,57,78,121,140,164,214,227,233,250],"E-cadherin":[44,59,80,180,202,236,252],"play":[45],"important":[47],"role":[48],"tumor":[50],"invasion.":[51],"In":[52,177],"this":[53],"study":[54],"we":[55],"analyzed":[56],"liquid-based":[62],"cervical":[63,84,145,185,247,256,268,276],"cytology":[64,257],"samples,":[65],"evaluated":[67],"their":[68],"potential":[69,262],"as":[71,239],"prognostic":[72,263],"immunomarkers.":[73],"METHODS:":[74],"Immunocytochemical":[75],"staining":[76,98,216],"was":[81,94,105,130,142,166,182,204,217],"performed":[82,95],"samples":[85,147,149,157,187,189,258],"125":[87],"patients.":[88],"cytological":[90],"or":[91,99],"histological":[92],"diagnostic":[93],"Papanicolaou":[97],"H&E":[100],"staining,":[101],"respectively.":[102],"HPV":[103,114],"genotyping":[104],"determined":[106,131],"using":[107],"INNO-LIPA":[108],"Genotyping":[109],"Extra":[110],"kit":[111],"physical":[115,175],"status":[116],"situ":[119],"hybridization.":[120],"HaCaT,":[124],"HeLa":[125],"SiHa":[127],"cell":[128],"lines":[129],"immunocytochemistry,":[133],"immunofluorescence":[134],"Western":[136],"blot.":[137],"RESULTS:":[138],"High":[139,163,226],"observed":[143],"(70%),":[148],"with":[150,158,168,190,206,219,270],"multiple":[151,191],"infection":[152,192],"HR-HPV":[154],"(43%),":[155],"integrated":[159,197],"viral":[160,172,198,211,224],"genome":[161,199],"(47%).":[162],"associated":[167,205,218],"degree":[169,207,220],"SIL,":[171],"genotype":[173],"status.":[176],"contrast,":[178],"low":[179,235],"found":[183],"(95%),":[188],"HR-HPV/LR-HPV":[194],"(87%)":[195],"(72%).":[200],"Low":[201],"SIL":[209,222],"genotype.":[212,225],"Interestingly,":[213],"nuclear":[215,232],"expression,":[228],"high":[229],"percent":[230],"behaved":[238],"risk":[240],"factors":[241],"progression":[243,274],"HSIL":[245],"cancer.":[248,277],"CONCLUSIONS:":[249],"profile":[254],"could":[259],"be":[260],"a":[261,271],"marker,":[264],"useful":[265],"identifying":[267],"lesions":[269],"high-risk":[272]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2018-06-01T00:00:00"}