{"id":"https://openalex.org/W2804843961","doi":null,"title":"Discovery of Peptide and Aptamer Ligands for Targeted Drug Delivery to Hepatic Stellate Cells","display_name":"Discovery of Peptide and Aptamer Ligands for Targeted Drug Delivery to Hepatic Stellate Cells","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2804843961","mag":"2804843961"},"language":"en","primary_location":{"id":"pmh:oai:https://mospace.umsystem.edu:10355/62413","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/10355/62413","pdf_url":null,"source":{"id":"https://openalex.org/S4306400929","display_name":"MOspace Institutional Repository (University of Missouri)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I76835614","host_organization_name":"University of Missouri","host_organization_lineage":["https://openalex.org/I76835614"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083717693","display_name":"Zhijin Chen","orcid":"https://orcid.org/0000-0001-5497-5418","observed_orcids":["https://orcid.org/0000-0001-5497-5418"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Zhijin Chen","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5497-5418","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5083717693"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.7289999723434448,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.7289999723434448,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.08799999952316284,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.05480000004172325,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/peptide-ligands","display_name":"peptide ligands","score":0.9309999942779541},{"id":"https://openalex.org/keywords/aptamers","display_name":"aptamers","score":0.9490000009536743},{"id":"https://openalex.org/keywords/targeted-drug-delivery","display_name":"targeted drug delivery","score":0.8199999928474426},{"id":"https://openalex.org/keywords/hepatic-stellate-cells","display_name":"hepatic stellate cells","score":0.9959999918937683},{"id":"https://openalex.org/keywords/liver-fibrosis","display_name":"liver fibrosis","score":0.765999972820282},{"id":"https://openalex.org/keywords/ligand-discovery","display_name":"ligand discovery","score":0.6959999799728394}],"concepts":[{"id":"https://openalex.org/C128972844","wikidata":"https://www.wikidata.org/wiki/Q418722","display_name":"Aptamer","level":2,"score":0.8222041726112366},{"id":"https://openalex.org/C176891718","wikidata":"https://www.wikidata.org/wiki/Q1997459","display_name":"Hepatic stellate cell","level":2,"score":0.8172257542610168},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.6279377937316895},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.5401249527931213},{"id":"https://openalex.org/C126511603","wikidata":"https://www.wikidata.org/wiki/Q1261145","display_name":"Targeted drug delivery","level":3,"score":0.4966321587562561},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.47598448395729065},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.4483189582824707},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4424106478691101},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.35334867238998413},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.328945517539978},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.32590678334236145},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3148937225341797},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.30507463216781616},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.28625595569610596},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2703682780265808},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.22654008865356445},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17616817355155945},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.1744653582572937}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:https://mospace.umsystem.edu:10355/62413","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/10355/62413","pdf_url":null,"source":{"id":"https://openalex.org/S4306400929","display_name":"MOspace Institutional Repository (University of Missouri)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I76835614","host_organization_name":"University of Missouri","host_organization_lineage":["https://openalex.org/I76835614"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"mag:2804843961","doi":null,"is_oa":false,"landing_page_url":"https://mospace.umsystem.edu/xmlui/handle/10355/62413","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":87,"referenced_works":["https://openalex.org/W40038083","https://openalex.org/W164180253","https://openalex.org/W201653061","https://openalex.org/W623769780","https://openalex.org/W1570961382","https://openalex.org/W1867757591","https://openalex.org/W1964858690","https://openalex.org/W1970620838","https://openalex.org/W1982484050","https://openalex.org/W1984547337","https://openalex.org/W1985117411","https://openalex.org/W1988222283","https://openalex.org/W1989706063","https://openalex.org/W1990046017","https://openalex.org/W1991863368","https://openalex.org/W1993698899","https://openalex.org/W2004297346","https://openalex.org/W2008292035","https://openalex.org/W2009288651","https://openalex.org/W2009928329","https://openalex.org/W2013461651","https://openalex.org/W2021298631","https://openalex.org/W2022821706","https://openalex.org/W2023394638","https://openalex.org/W2023851810","https://openalex.org/W2025780125","https://openalex.org/W2028876701","https://openalex.org/W2030187502","https://openalex.org/W2035199411","https://openalex.org/W2036860072","https://openalex.org/W2038287048","https://openalex.org/W2041808787","https://openalex.org/W2042195196","https://openalex.org/W2042362670","https://openalex.org/W2043893097","https://openalex.org/W2046619729","https://openalex.org/W2057453910","https://openalex.org/W2060556645","https://openalex.org/W2067464700","https://openalex.org/W2070360032","https://openalex.org/W2073619242","https://openalex.org/W2074988418","https://openalex.org/W2077130806","https://openalex.org/W2078728864","https://openalex.org/W2079619166","https://openalex.org/W2083145744","https://openalex.org/W2092473496","https://openalex.org/W2093487276","https://openalex.org/W2094781240","https://openalex.org/W2094850312","https://openalex.org/W2098735533","https://openalex.org/W2104021296","https://openalex.org/W2116532751","https://openalex.org/W2120145250","https://openalex.org/W2121502611","https://openalex.org/W2122129759","https://openalex.org/W2124398672","https://openalex.org/W2124532149","https://openalex.org/W2125065061","https://openalex.org/W2127019408","https://openalex.org/W2127036976","https://openalex.org/W2127409621","https://openalex.org/W2129360146","https://openalex.org/W2133777928","https://openalex.org/W2136095967","https://openalex.org/W2148443505","https://openalex.org/W2152956716","https://openalex.org/W2153823758","https://openalex.org/W2154169185","https://openalex.org/W2156113162","https://openalex.org/W2157263411","https://openalex.org/W2158129157","https://openalex.org/W2165558786","https://openalex.org/W2165606462","https://openalex.org/W2165715544","https://openalex.org/W2166575264","https://openalex.org/W2167485180","https://openalex.org/W2167991331","https://openalex.org/W2168091540","https://openalex.org/W2170756509","https://openalex.org/W2191158185","https://openalex.org/W2331423836","https://openalex.org/W2334703606","https://openalex.org/W2382181809","https://openalex.org/W2395531905","https://openalex.org/W2741635669","https://openalex.org/W3148913165"],"related_works":["https://openalex.org/W4405419929","https://openalex.org/W4306693904","https://openalex.org/W3129542242","https://openalex.org/W2046964009","https://openalex.org/W2414903414","https://openalex.org/W2012854681","https://openalex.org/W623769780","https://openalex.org/W2582863035","https://openalex.org/W2745709894","https://openalex.org/W6893118953"],"abstract_inverted_index":{"Title":[0],"from":[1],"PDF":[2],"of":[3],"title":[4],"page,":[5],"viewed":[6],"January":[7],"3,":[8],"2018":[9]},"counts_by_year":[],"updated_date":"2026-09-12T09:15:50.089291","created_date":"2018-06-01T00:00:00"}