{"id":"https://openalex.org/W2804556902","doi":null,"title":"Insights into the Functional Roles of Exercise in Type 2 Diabetes Using in vitro Models","display_name":"Insights into the Functional Roles of Exercise in Type 2 Diabetes Using in vitro Models","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2804556902","mag":"2804556902"},"language":"en","primary_location":{"id":"pmh:oai:etd.ohiolink.edu:case1512565582988227","doi":null,"is_oa":true,"landing_page_url":"http://rave.ohiolink.edu/etdc/view?acc_num=case1512565582988227","pdf_url":"https://etd.ohiolink.edu/acprod/odb_etd/ws/send_file/send?accession=case1512565582988227&disposition=inline","source":{"id":"https://openalex.org/S4377196344","display_name":"OhioLink ETD Center (Ohio Library and Information Network)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210155183","host_organization_name":"Ohio Library and Information Network","host_organization_lineage":["https://openalex.org/I4210155183"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://rave.ohiolink.edu/etdc/view?acc_num=case1512565582988227","raw_type":"text"},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://etd.ohiolink.edu/acprod/odb_etd/ws/send_file/send?accession=case1512565582988227&disposition=inline","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001841600","display_name":"Stephan Nieuwoudt","orcid":"https://orcid.org/0000-0003-4857-2211","observed_orcids":["https://orcid.org/0000-0003-4857-2211"]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Stephan Nieuwoudt","raw_affiliation_strings":["Case Western Reserve University"],"raw_orcid":"https://orcid.org/0000-0003-4857-2211","affiliations":[{"raw_affiliation_string":"Case Western Reserve University","institution_ids":["https://openalex.org/I58956616"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5001841600"],"corresponding_institution_ids":["https://openalex.org/I58956616"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.10904293,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.7060999870300293,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.7060999870300293,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10352","display_name":"Physical Activity and Health","score":0.09130000323057175,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.06509999930858612,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9990000128746033},{"id":"https://openalex.org/keywords/exercise","display_name":"physical activity","score":0.6830000281333923},{"id":"https://openalex.org/keywords/beta-cell-function","display_name":"beta-cell function","score":0.8619999885559082},{"id":"https://openalex.org/keywords/insulin-secretion","display_name":"insulin secretion","score":0.7850000262260437},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.8349999785423279},{"id":"https://openalex.org/keywords/high-intensity-interval-training","display_name":"high-intensity interval training","score":0.6480000019073486},{"id":"https://openalex.org/keywords/crossfit","display_name":"CrossFit","score":0.7559999823570251},{"id":"https://openalex.org/keywords/skeletal-muscle","display_name":"skeletal muscle","score":0.46799999475479126},{"id":"https://openalex.org/keywords/sedentary-adults","display_name":"sedentary adults","score":0.8560000061988831}],"concepts":[{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.6044830679893494},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.40732190012931824},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.401626855134964},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.35360825061798096},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.31171756982803345},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.15591275691986084}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:etd.ohiolink.edu:case1512565582988227","doi":null,"is_oa":true,"landing_page_url":"http://rave.ohiolink.edu/etdc/view?acc_num=case1512565582988227","pdf_url":"https://etd.ohiolink.edu/acprod/odb_etd/ws/send_file/send?accession=case1512565582988227&disposition=inline","source":{"id":"https://openalex.org/S4377196344","display_name":"OhioLink ETD Center (Ohio Library and Information Network)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210155183","host_organization_name":"Ohio Library and Information Network","host_organization_lineage":["https://openalex.org/I4210155183"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://rave.ohiolink.edu/etdc/view?acc_num=case1512565582988227","raw_type":"text"},{"id":"mag:2804556902","doi":null,"is_oa":false,"landing_page_url":"https://etd.ohiolink.edu/pg_10?0::NO:10:P10_ETD_SUBID:158278","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:etd.ohiolink.edu:case1512565582988227","doi":null,"is_oa":true,"landing_page_url":"http://rave.ohiolink.edu/etdc/view?acc_num=case1512565582988227","pdf_url":"https://etd.ohiolink.edu/acprod/odb_etd/ws/send_file/send?accession=case1512565582988227&disposition=inline","source":{"id":"https://openalex.org/S4377196344","display_name":"OhioLink ETD Center (Ohio Library and Information Network)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210155183","host_organization_name":"Ohio Library and Information Network","host_organization_lineage":["https://openalex.org/I4210155183"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://rave.ohiolink.edu/etdc/view?acc_num=case1512565582988227","raw_type":"text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2804556902.pdf","grobid_xml":"https://content.openalex.org/works/W2804556902.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2616792756","https://openalex.org/W7156590706","https://openalex.org/W22755577","https://openalex.org/W4281716199","https://openalex.org/W2784044415","https://openalex.org/W7162448100","https://openalex.org/W4393097884","https://openalex.org/W3148746985","https://openalex.org/W4211228962","https://openalex.org/W4289933147"],"abstract_inverted_index":{"Type":[0],"2":[1],"diabetes":[2],"(T2D)":[3],"is":[4],"characterized":[5],"by":[6],"reductions":[7],"in":[8,50,74],"\u03b2-cell":[9,27,48,72],"function":[10,49,73],"and":[11],"insulin":[12,19],"secretion":[13],"on":[14,47,71],"the":[15,40,51,58],"background":[16],"of":[17,32,42,45,60],"elevated":[18],"resistance.Aerobic":[20],"exercise":[21,46],"has":[22],"been":[23],"shown":[24],"to":[25],"improve":[26],"function,":[28],"despite":[29],"a":[30,61],"subset":[31],"T2D":[33,52],"patients":[34],"displaying":[35],"\"exercise":[36],"resistance\".Further":[37],"investigations":[38],"into":[39],"effectiveness":[41],"alternate":[43],"forms":[44],"patient":[53],"population":[54],"are":[55],"needed.We":[56],"examined":[57],"effect":[59],"novel":[62],"6-week":[63],"CrossFit\u2122":[64],"Functional":[65],"High":[66],"Intensity":[67],"Training":[68],"(F-HIT)":[69],"intervention":[70],"12":[75],"sedentary":[76],"adults":[77],"with":[78],"clinically":[79],"In":[80],"Vitro":[81],"Contraction":[82]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2018-06-01T00:00:00"}