{"id":"https://openalex.org/W2804522015","doi":"https://doi.org/10.1093/ageing/afy080","title":"Cardiovascular risk factors and frailty in a cross-sectional study of older people: implications for prevention","display_name":"Cardiovascular risk factors and frailty in a cross-sectional study of older people: implications for prevention","publication_year":2018,"publication_date":"2018-05-18","ids":{"openalex":"https://openalex.org/W2804522015","doi":"https://doi.org/10.1093/ageing/afy080","mag":"2804522015","pmid":"https://pubmed.ncbi.nlm.nih.gov/29796607","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6108388"},"language":"en","primary_location":{"id":"doi:10.1093/ageing/afy080","doi":"https://doi.org/10.1093/ageing/afy080","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ageing/afy080","pdf_url":"https://academic.oup.com/ageing/article-pdf/47/5/714/25538606/afy080.pdf","source":{"id":"https://openalex.org/S31768639","display_name":"Age and Ageing","issn_l":"0002-0729","issn":["0002-0729","1468-2834"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Age and Ageing","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/ageing/article-pdf/47/5/714/25538606/afy080.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101515464","display_name":"Tsz Yan Wong","orcid":"https://orcid.org/0000-0003-2554-7638","observed_orcids":["https://orcid.org/0000-0003-2554-7638"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tsz Yan Wong","raw_affiliation_strings":["Nuffield Department of Population Health, University of Oxford, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nuffield Department of Population Health, University of Oxford, Oxford, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087103035","display_name":"Maria Sofia Massa","orcid":"https://orcid.org/0000-0003-3205-6706","observed_orcids":["https://orcid.org/0000-0003-3205-6706"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M Sofia Massa","raw_affiliation_strings":["Nuffield Department of Population Health, University of Oxford, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nuffield Department of Population Health, University of Oxford, Oxford, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020942101","display_name":"Aisling M O\u2019Halloran","orcid":"https://orcid.org/0000-0001-5498-4453","observed_orcids":["https://orcid.org/0000-0001-5498-4453"]},"institutions":[{"id":"https://openalex.org/I205274468","display_name":"Trinity College Dublin","ror":"https://ror.org/02tyrky19","country_code":"IE","type":"education","lineage":["https://openalex.org/I205274468"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Aisling M O'Halloran","raw_affiliation_strings":["TILDA, Department of Medical Gerontology, Trinity College, Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"TILDA, Department of Medical Gerontology, Trinity College, Dublin, Ireland","institution_ids":["https://openalex.org/I205274468"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027947710","display_name":"Rose Anne Kenny","orcid":"https://orcid.org/0000-0002-9336-8124","observed_orcids":["https://orcid.org/0000-0002-9336-8124"]},"institutions":[{"id":"https://openalex.org/I205274468","display_name":"Trinity College Dublin","ror":"https://ror.org/02tyrky19","country_code":"IE","type":"education","lineage":["https://openalex.org/I205274468"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Rose Ann Kenny","raw_affiliation_strings":["TILDA, Department of Medical Gerontology, Trinity College, Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"TILDA, Department of Medical Gerontology, Trinity College, Dublin, Ireland","institution_ids":["https://openalex.org/I205274468"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042642059","display_name":"Robert Clarke","orcid":"https://orcid.org/0000-0002-9802-8241","observed_orcids":["https://orcid.org/0000-0002-9802-8241"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Robert Clarke","raw_affiliation_strings":["Nuffield Department of Population Health, University of Oxford, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nuffield Department of Population Health, University of Oxford, Oxford, UK","institution_ids":["https://openalex.org/I40120149"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5042642059"],"corresponding_institution_ids":["https://openalex.org/I40120149"],"apc_list":{"value":2805,"currency":"GBP","value_usd":3699},"apc_paid":{"value":2805,"currency":"GBP","value_usd":3699},"fwci":0.5006,"has_fulltext":true,"cited_by_count":47,"citation_normalized_percentile":{"value":0.46413502,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"47","issue":"5","first_page":"714","last_page":"720"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11011","display_name":"Frailty in Older Adults","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11011","display_name":"Frailty in Older Adults","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13522","display_name":"Cardiovascular Health and Risk Factors","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/frailty","display_name":"frailty","score":0.9079999923706055},{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.9860000014305115},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.9760000109672546},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.6740000247955322},{"id":"https://openalex.org/keywords/frailty-index","display_name":"frailty index","score":0.8550000190734863},{"id":"https://openalex.org/keywords/score-risk-score","display_name":"SCORE risk score","score":0.9139999747276306},{"id":"https://openalex.org/keywords/ideal-cardiovascular-health","display_name":"ideal cardiovascular health","score":0.8700000047683716},{"id":"https://openalex.org/keywords/cardiovascular-health-metrics","display_name":"cardiovascular health metrics","score":0.9850000143051147},{"id":"https://openalex.org/keywords/disability-prevention","display_name":"disability prevention","score":0.6840000152587891},{"id":"https://openalex.org/keywords/cardiovascular-health","display_name":"cardiovascular health","score":0.3959999978542328}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.928605318069458},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.6218340396881104},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.6216983795166016},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.5336989164352417},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5023140907287598},{"id":"https://openalex.org/C2909041561","wikidata":"https://www.wikidata.org/wiki/Q25099514","display_name":"Frailty Index","level":2,"score":0.49096181988716125},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.47364842891693115},{"id":"https://openalex.org/C142052008","wikidata":"https://www.wikidata.org/wiki/Q954027","display_name":"Cross-sectional study","level":2,"score":0.459585577249527},{"id":"https://openalex.org/C11783203","wikidata":"https://www.wikidata.org/wiki/Q5478027","display_name":"Framingham Risk Score","level":3,"score":0.4223668873310089},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3931272029876709},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.3424317538738251},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.32589924335479736},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000073496","descriptor_name":"Frailty","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D000073496","descriptor_name":"Frailty","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D000073496","descriptor_name":"Frailty","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D000073496","descriptor_name":"Frailty","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D000203","descriptor_name":"Activities of Daily Living","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D003362","descriptor_name":"Cost-Benefit Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009426","descriptor_name":"Netherlands","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D011320","descriptor_name":"Primary Health Care","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012919","descriptor_name":"Social Behavior","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016330","descriptor_name":"Frail Elderly","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017048","descriptor_name":"Health Care Costs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018570","descriptor_name":"Risk Assessment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018849","descriptor_name":"Controlled Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019033","descriptor_name":"Delivery of Health Care, Integrated","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D058006","descriptor_name":"General Practice","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true}],"locations_count":7,"locations":[{"id":"doi:10.1093/ageing/afy080","doi":"https://doi.org/10.1093/ageing/afy080","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ageing/afy080","pdf_url":"https://academic.oup.com/ageing/article-pdf/47/5/714/25538606/afy080.pdf","source":{"id":"https://openalex.org/S31768639","display_name":"Age and Ageing","issn_l":"0002-0729","issn":["0002-0729","1468-2834"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Age and Ageing","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5064456","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6108388","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:29796607","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29796607","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Age and ageing","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6108388","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6108388/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Age Ageing","raw_type":"Text"},{"id":"pmh:http://www.rian.ie/169664/","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2262/89282","pdf_url":"http://hdl.handle.net/2262/89282","source":{"id":"https://openalex.org/S4306400033","display_name":"Arrow@dit (Dublin Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210144925","host_organization_name":"Technological University Dublin","host_organization_lineage":["https://openalex.org/I4210144925"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Wong TY, Massa MS, O'Halloran AM, Kenny RA, Clarke R., Cardiovascular risk factors and frailty in a cross-sectional study of older people: implications for prevention., Age and ageing, 47, 5, 2018, 714-720","raw_type":"Journal article"},{"id":"pmh:oai:ora.ox.ac.uk:uuid:3df458dd-dfd7-4605-95dc-12a18be72c54","doi":null,"is_oa":true,"landing_page_url":"https://ora.ox.ac.uk/objects/uuid:3df458dd-dfd7-4605-95dc-12a18be72c54","pdf_url":"https://ora.ox.ac.uk/objects/uuid:3df458dd-dfd7-4605-95dc-12a18be72c54/files/mc63243bfd6e939199380682480d00445","source":{"id":"https://openalex.org/S4306402636","display_name":"Oxford University Research Archive (ORA) (University of Oxford)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I40120149","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/I40120149"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Symplectic Elements at Oxford","raw_type":"Journal article"},{"id":"pmh:oai:tara.tcd.ie:2262/89282","doi":null,"is_oa":false,"landing_page_url":"https://academic.oup.com/ageing/article/47/5/714/5001516","pdf_url":null,"source":{"id":"https://openalex.org/S4306400387","display_name":"Trinity's Access to Research Output (TARA) (Trinity College Dublin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205274468","host_organization_name":"Trinity College Dublin","host_organization_lineage":["https://openalex.org/I205274468"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1093/ageing/afy080","doi":"https://doi.org/10.1093/ageing/afy080","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ageing/afy080","pdf_url":"https://academic.oup.com/ageing/article-pdf/47/5/714/25538606/afy080.pdf","source":{"id":"https://openalex.org/S31768639","display_name":"Age and Ageing","issn_l":"0002-0729","issn":["0002-0729","1468-2834"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Age and Ageing","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G2628120876","display_name":null,"funder_award_id":"CH/1996001/9454","funder_id":"https://openalex.org/F4320319992","funder_display_name":"British Heart Foundation"},{"id":"https://openalex.org/G3101934771","display_name":"Does vitamin D supplementation improve markers of inflammation, innate immunity and arterial stiffness?","funder_award_id":"PG/12/32/29544","funder_id":"https://openalex.org/F4320319992","funder_display_name":"British Heart Foundation"}],"funders":[{"id":"https://openalex.org/F4320319992","display_name":"British Heart Foundation","ror":"https://ror.org/02wdwnk04"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2804522015.pdf","grobid_xml":"https://content.openalex.org/works/W2804522015.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W176006575","https://openalex.org/W1525217260","https://openalex.org/W1600230915","https://openalex.org/W1966287229","https://openalex.org/W1969048420","https://openalex.org/W1990619096","https://openalex.org/W2001629081","https://openalex.org/W2034589827","https://openalex.org/W2035774055","https://openalex.org/W2077411129","https://openalex.org/W2087103083","https://openalex.org/W2096489972","https://openalex.org/W2098726460","https://openalex.org/W2105092978","https://openalex.org/W2107165713","https://openalex.org/W2113870267","https://openalex.org/W2139520621","https://openalex.org/W2139789661","https://openalex.org/W2142514031","https://openalex.org/W2146172316","https://openalex.org/W2149811613","https://openalex.org/W2156848121","https://openalex.org/W2164059021","https://openalex.org/W2247997571","https://openalex.org/W2273439767","https://openalex.org/W2291720716","https://openalex.org/W2380544456","https://openalex.org/W2385807718","https://openalex.org/W2402203869","https://openalex.org/W2402599050","https://openalex.org/W3021842026"],"related_works":["https://openalex.org/W3182671855","https://openalex.org/W1990619096","https://openalex.org/W2799136169","https://openalex.org/W2582378536","https://openalex.org/W4406706443","https://openalex.org/W2385807718","https://openalex.org/W4414211042","https://openalex.org/W2944943772","https://openalex.org/W2103809032","https://openalex.org/W7095699709"],"abstract_inverted_index":{"Objective:":[0],"to":[1,85,114,169],"examine":[2],"the":[3,20,90,120,172,214,230],"associations":[4,91,217,222],"of":[5,38,45,92,106,142,180,206,218,223,233,236,242],"cardiovascular":[6,10,51],"disease":[7],"(CVD)":[8],"and":[9,35,71,119,163,195,220,225],"risk":[11,52,60,94,144,156,187,238],"factors":[12,53,95,145,239],"with":[13,41,96,126,149,166,184,198,200,210,227],"frailty.":[14,88,167],"Design:":[15],"a":[16,36,79],"cross-sectional":[17],"study.":[18],"Setting:":[19],"Irish":[21],"Longitudinal":[22],"Study":[23],"on":[24,32],"Ageing":[25],"(TILDA).":[26],"Participants:":[27],"frailty":[28,80,97,109,151,181,228],"measures":[29],"were":[30,54,98,146,161],"obtained":[31],"5,618":[33],"participants":[34,40,107],"subset":[37],"4,330":[39],"no":[42],"prior":[43,130,138],"history":[44],"CVD.":[46],"Exposures":[47],"for":[48,87,182,203,240],"observational":[49],"study:":[50],"combined":[55],"in":[56,124,244],"three":[57],"composite":[58],"CVD":[59,93,131,143,155,237],"scores":[61],"(Systematic":[62],"Coronary":[63],"Risk":[64],"Evaluation":[65],"[SCORE],":[66],"Ideal":[67],"Cardiovascular":[68,72],"Health":[69,73],"[ICH]":[70],"Metrics":[74],"[CHM]).":[75],"Main":[76],"outcome":[77],"measures:":[78],"index":[81,152],"(40-items)":[82],"was":[83,122,188,193],"used":[84],"screen":[86],"Methods:":[89],"examined":[99],"using":[100,159],"logistic":[101],"regression.":[102],"Results:":[103],"overall,":[104],"16.4%":[105],"had":[108],"(7.6%":[110],"at":[111,116],"50-59":[112],"years":[113],"42.5%":[115],"80+":[117],"years),":[118],"prevalence":[121],"higher":[123,150],"those":[125,128,136,183],"versus":[127],"without":[129,137],"(43.0%":[132],"vs.":[133],"10.7%).":[134],"Among":[135],"CVD,":[139],"mean":[140],"levels":[141,235],"closely":[147],"correlated":[148],"scores.":[153],"Combined":[154],"factors,":[157],"assessed":[158],"SCORE,":[160],"linearly":[162,194],"positively":[164],"associated":[165,197],"Compared":[168],"low-to-moderate":[170],"SCOREs,":[171],"odds":[173],"ratio":[174],"(OR)":[175],"(95%":[176],"confidence":[177],"interval,":[178],"CI)":[179],"very":[185],"high":[186],"3.18":[189],"(2.38-4.25).":[190],"Conversely,":[191],"ICH":[192,224],"inversely":[196],"frailty,":[199],"an":[201],"OR":[202],"optimal":[204],"health":[205],"0.29":[207],"(0.21-0.40)":[208],"compared":[209],"inadequate":[211],"health.":[212],"Conclusions:":[213],"concordant":[215],"positive":[216],"SCORE":[219],"inverse":[221],"CHM":[226],"highlight":[229],"potential":[231],"importance":[232],"optimum":[234],"prevention":[241],"disability":[243],"frail":[245],"older":[246],"people.":[247]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":12},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2018-06-01T00:00:00"}