{"id":"https://openalex.org/W2804316037","doi":null,"title":"Ethylglucuronide replacing ethanol in the routine screening of alcohol dependent outpatients: clinical implications","display_name":"Ethylglucuronide replacing ethanol in the routine screening of alcohol dependent outpatients: clinical implications","publication_year":2017,"publication_date":"2017-06-16","ids":{"openalex":"https://openalex.org/W2804316037","mag":"2804316037"},"language":"en","primary_location":{"id":"pmh:oai:dnet:tdr_________::0307ea3f3c8af4662997019b2ac4a373","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10803/565576","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"TDX (Tesis Doctorals en Xarxa)","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10803/565576","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021973355","display_name":"Pablo Gimenez","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Pablo Gimenez","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5021973355"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10043","display_name":"Substance Abuse Treatment and Outcomes","score":0.9702000021934509,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10043","display_name":"Substance Abuse Treatment and Outcomes","score":0.9702000021934509,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.02280000038444996,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.004800000227987766,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ethyl-glucuronide","display_name":"ethyl glucuronide","score":0.9789999723434448},{"id":"https://openalex.org/keywords/alcohol-biomarkers","display_name":"alcohol biomarkers","score":0.6449999809265137},{"id":"https://openalex.org/keywords/alcoholism","display_name":"alcoholism","score":0.718999981880188},{"id":"https://openalex.org/keywords/urine-screening","display_name":"urine screening","score":0.6830000281333923},{"id":"https://openalex.org/keywords/ethanol-detection","display_name":"ethanol detection","score":0.5249999761581421},{"id":"https://openalex.org/keywords/relapse","display_name":"relapse","score":0.7269999980926514},{"id":"https://openalex.org/keywords/hospitalization","display_name":"hospitalization","score":0.6430000066757202},{"id":"https://openalex.org/keywords/treatment-costs","display_name":"treatment costs","score":0.9679999947547913},{"id":"https://openalex.org/keywords/patient-attitudes","display_name":"patient attitudes","score":0.8450000286102295},{"id":"https://openalex.org/keywords/drug-attitude-inventory","display_name":"Drug Attitude Inventory","score":0.9020000100135803},{"id":"https://openalex.org/keywords/outpatients","display_name":"outpatients","score":0.7310000061988831},{"id":"https://openalex.org/keywords/screening-validation","display_name":"screening validation","score":0.460999995470047},{"id":"https://openalex.org/keywords/patient-centered-care","display_name":"patient-centered care","score":0.6240000128746033},{"id":"https://openalex.org/keywords/patient-knowledge-and-beliefs","display_name":"patient knowledge and beliefs","score":0.42500001192092896}],"concepts":[{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.7074025273323059},{"id":"https://openalex.org/C3019635848","wikidata":"https://www.wikidata.org/wiki/Q154","display_name":"Alcohol consumption","level":3,"score":0.5066202878952026},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.38641202449798584},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.3810330927371979},{"id":"https://openalex.org/C2781066024","wikidata":"https://www.wikidata.org/wiki/Q156","display_name":"Alcohol","level":2,"score":0.3154037594795227},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.06249105930328369},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:dnet:tdr_________::0307ea3f3c8af4662997019b2ac4a373","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10803/565576","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"TDX (Tesis Doctorals en Xarxa)","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"pmh:oai:diposit.ub.edu:2445/122551","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2445/122551","pdf_url":"http://hdl.handle.net/2445/122551","source":{"id":"https://openalex.org/S4306401653","display_name":"Dip\u00f2sit Digital de la Universitat de Barcelona (Universitat de Barcelona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I71999127","host_organization_name":"Universitat de Barcelona","host_organization_lineage":["https://openalex.org/I71999127"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Tesis Doctorals - Facultat - Medicina","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"pmh:oai:www.tdx.cat:10803/565576","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10803/565576","pdf_url":null,"source":{"id":"https://openalex.org/S4306401111","display_name":"Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210090028","host_organization_name":"Consorci de Serveis Universitaris de Catalunya","host_organization_lineage":["https://openalex.org/I4210090028"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"TDX (Tesis Doctorals en Xarxa)","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:2804316037","doi":null,"is_oa":false,"landing_page_url":"http://diposit.ub.edu/dspace/bitstream/2445/122551/1/PDG_PhD_THESIS.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4306531624","display_name":"TDX (Tesis Doctorals en Xarxa)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"TDX (Tesis Doctorals en Xarxa)","raw_type":null}],"best_oa_location":{"id":"pmh:oai:dnet:tdr_________::0307ea3f3c8af4662997019b2ac4a373","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10803/565576","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"TDX (Tesis Doctorals en Xarxa)","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2804316037.pdf","grobid_xml":"https://content.openalex.org/works/W2804316037.grobid-xml"},"referenced_works_count":91,"referenced_works":["https://openalex.org/W116495858","https://openalex.org/W190568569","https://openalex.org/W1480451672","https://openalex.org/W1587172963","https://openalex.org/W1837577742","https://openalex.org/W1906481293","https://openalex.org/W1921681698","https://openalex.org/W1923606131","https://openalex.org/W1964631257","https://openalex.org/W1966583118","https://openalex.org/W1967925128","https://openalex.org/W1969981693","https://openalex.org/W1981833356","https://openalex.org/W1982725529","https://openalex.org/W1984982865","https://openalex.org/W1985893347","https://openalex.org/W1986695894","https://openalex.org/W1990262916","https://openalex.org/W1997828752","https://openalex.org/W1999172153","https://openalex.org/W1999957028","https://openalex.org/W2002418093","https://openalex.org/W2002490825","https://openalex.org/W2004482046","https://openalex.org/W2009781329","https://openalex.org/W2011228682","https://openalex.org/W2015712245","https://openalex.org/W2024961803","https://openalex.org/W2026287149","https://openalex.org/W2035068440","https://openalex.org/W2048431337","https://openalex.org/W2052957879","https://openalex.org/W2056989663","https://openalex.org/W2058056495","https://openalex.org/W2058367964","https://openalex.org/W2062666787","https://openalex.org/W2064379162","https://openalex.org/W2082518171","https://openalex.org/W2086084056","https://openalex.org/W2089009141","https://openalex.org/W2094545740","https://openalex.org/W2095770639","https://openalex.org/W2097787837","https://openalex.org/W2097929576","https://openalex.org/W2101372918","https://openalex.org/W2102344267","https://openalex.org/W2104927872","https://openalex.org/W2105541289","https://openalex.org/W2106752000","https://openalex.org/W2111086034","https://openalex.org/W2112454287","https://openalex.org/W2114013309","https://openalex.org/W2117617079","https://openalex.org/W2123602227","https://openalex.org/W2123613968","https://openalex.org/W2124273275","https://openalex.org/W2124390845","https://openalex.org/W2126294191","https://openalex.org/W2126751162","https://openalex.org/W2127005324","https://openalex.org/W2130612489","https://openalex.org/W2133058012","https://openalex.org/W2133570541","https://openalex.org/W2135168571","https://openalex.org/W2136808996","https://openalex.org/W2138274743","https://openalex.org/W2142458821","https://openalex.org/W2143617104","https://openalex.org/W2146132889","https://openalex.org/W2146140851","https://openalex.org/W2147980944","https://openalex.org/W2148151848","https://openalex.org/W2149736996","https://openalex.org/W2156081308","https://openalex.org/W2160397887","https://openalex.org/W2169143941","https://openalex.org/W2169794763","https://openalex.org/W2172962518","https://openalex.org/W2242899965","https://openalex.org/W2286419936","https://openalex.org/W2332292742","https://openalex.org/W2339902340","https://openalex.org/W2343440595","https://openalex.org/W2401897839","https://openalex.org/W2410345663","https://openalex.org/W2473481037","https://openalex.org/W2528323951","https://openalex.org/W2593770410","https://openalex.org/W2594472445","https://openalex.org/W2906253013","https://openalex.org/W4360755029"],"related_works":["https://openalex.org/W2781210232","https://openalex.org/W7048066631","https://openalex.org/W194875586","https://openalex.org/W2141244698","https://openalex.org/W2024502190","https://openalex.org/W2401897839","https://openalex.org/W47259953","https://openalex.org/W4367592265","https://openalex.org/W73516978","https://openalex.org/W181728558"],"abstract_inverted_index":{"BACKGROUND:":[0],"\\nThe":[1],"development":[2],"of":[3,36,58,68,87,110,126,155,190,231,248,265,272,297,327,352,366,400,465,473,479],"an":[4,349,459,480],"alcohol":[5,111,141,182,216,287,311,328,414,420,450,466],"biomarker":[6],"is":[7,416],"a":[8,92,191,283,362,376,442,470],"long":[9],"process":[10],"where":[11],"different":[12,378],"stages":[13],"take":[14],"place":[15],"over":[16,354],"time.":[17],"From":[18],"discovery":[19],"to":[20,73,82,102,107,244,260,275,324,432,457],"full":[21],"clinical":[22,85,131,153,168,202,229,356,379,463],"use":[23,112],"and":[24,33,53,65,133,159,169,178,222,253,277,307,335,358,384,403,438,476],"implementation,":[25],"each":[26],"accomplished":[27],"stage":[28],"increases":[29],"the":[30,34,51,56,62,77,84,108,118,123,150,228,246,262,270,295,319,325,341,388,462,477],"confidence":[31],"in":[32,50,100,140,161,234,242,369,405],"relevance":[35],"such":[37,69,88],"biomarkers.":[38],"In":[39,280,292],"recent":[40,59,474],"years,":[41],"new":[42,89],"biomarkers":[43],"have":[44,458],"been":[45],"discovered,":[46],"with":[47,91,215,294,392,453],"outstanding":[48],"improvements":[49,71],"sensibility":[52],"specificity":[54],"for":[55,220,340],"detection":[57,472],"drinking.":[60],"However,":[61],"clinical,":[63],"therapeutic":[64,433],"economical":[66],"consequences":[67],"biochemical":[70],"remain":[72],"be":[74],"determined.":[75],"With":[76],"present":[78],"thesis":[79],"we":[80,317],"expect":[81],"investigate":[83],"implications":[86],"biomarkers,":[90],"special":[93],"focus":[94],"on":[95,461],"urine":[96,183,312,329,451],"ethyl":[97,127,454],"glucuronide":[98,128,455],"(EtG),":[99],"order":[101,243],"fully":[103],"establish":[104],"its":[105],"contribution":[106],"field":[109,326],"disorders.":[113],"It":[114,422],"comprises":[115],"three":[116],"articles:":[117],"first":[119],"(Study":[120,147],"1)":[121],"compares":[122],"screening":[124,157,415,452],"performance":[125],"versus":[129],"ethanol,":[130,355],"judgment":[132,357],"self":[134,359],"report,":[135,360],"under":[136,199],"routine,":[137,370],"real":[138,371],"circumstances":[139],"dependent":[142,288,467],"outpatients.":[143,421],"The":[144],"second":[145],"one":[146],"2)":[148],"investigates":[149],"differential,":[151],"one-year":[152],"evolution":[154,230,380],"patients":[156,232,386,395],"positive":[158,252,367,383,394],"negative":[160,254,385],"Study":[162,173,224,235,281,373,409],"1,":[163],"taking":[164],"into":[165],"account":[166],"both":[167],"economic":[170],"consequences.":[171],"Finally,":[172],"3":[174,282,410],"evaluates":[175],"patients\u2019":[176,305],"knowledge":[177],"attitudes":[179,306],"towards":[180,309],"regular":[181,310,413],"screening.":[184,313,330],"\\n":[185,344,447],"\\nMETHODS:":[186],"\\nStudy":[187,346],"1":[188,347],"consisted":[189],"cross-sectional":[192,284],"comparison":[193],"aiming":[194],"at":[195,303,397],"clinically":[196],"validating":[197],"EtG":[198,251,353,382,393],"real,":[200],"routinely":[201],"conditions.":[203],"For":[204,314],"that":[205,412,425],"purpose,":[206],"613":[207],"consecutive":[208],"urinary":[209],"samples,":[210],"provided":[211],"by":[212,419],"188":[213],"outpatients":[214,289],"dependence":[217],"were":[218,258,338],"analyzed":[219],"ethanol":[221],"EtG.":[223],"2":[225,374],"retrospectively":[226],"assessed":[227],"participating":[233],"1.":[236],"A":[237],"survival":[238],"analysis":[239],"was":[240,290],"conducted":[241],"compare":[245,261],"rate":[247],"relapse":[249,427,482],"between":[250,268,381],"patients.":[255],"Regression":[256],"models":[257],"performed":[259],"mean":[263],"number":[264,365],"days":[266],"hospitalized":[267],"groups,":[269],"risk":[271,399],"being":[273,396],"lost":[274],"follow-up":[276],"treatment":[278,407],"expenses.":[279,408],"survey":[285],"among":[286],"conducted.":[291],"consonance":[293],"principles":[296],"patient":[298],"centered":[299],"care,":[300],"it":[301],"aimed":[302],"investigating":[304],"beliefs":[308],"attitudes\u2019":[315],"assessment,":[316],"adapted":[318,342],"Drug":[320],"Attitude":[321],"Inventory":[322],"(DAI-10)":[323],"Internal":[331],"consistency,":[332],"test-retest":[333],"reliability":[334],"concurrent":[336],"validity":[337],"evaluated":[339],"questionnaire.":[343],"\\nRESULTS:":[345],"showed":[348,424],"overriding":[350],"superiority":[351],"detecting":[361],"significant":[363],"greater":[364,398],"samples":[368],"circumstances.":[372],"revealed":[375],"clearly":[377],"during":[387],"following":[389],"12":[390],"months,":[391],"relapse,":[401],"hospitalization":[402],"incurring":[404],"more":[406],"suggested":[411],"highly":[417],"valued":[418],"also":[423],"besides":[426],"prevention,":[428],"other":[429],"functions":[430],"related":[431],"alliance":[434],"building,":[435],"social":[436],"desirability":[437],"impression":[439],"management":[440,464],"play":[441],"key":[443],"role":[444],"as":[445],"well.":[446],"\\nCONCLUSIONS:":[448],"\\nRegular":[449],"seems":[456],"impact":[460],"outpatients,":[468],"offering":[469],"better":[471],"drinking":[475],"possibility":[478],"improved":[481],"prevention":[483],"strategy.":[484]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2018-06-01T00:00:00"}