{"id":"https://openalex.org/W2804299729","doi":"https://doi.org/10.1080/21691401.2018.1476371","title":"Development and characterization of polymeric-based nanoparticles for sustained release of amoxicillin \u2013 an antimicrobial drug","display_name":"Development and characterization of polymeric-based nanoparticles for sustained release of amoxicillin \u2013 an antimicrobial drug","publication_year":2018,"publication_date":"2018-05-26","ids":{"openalex":"https://openalex.org/W2804299729","doi":"https://doi.org/10.1080/21691401.2018.1476371","mag":"2804299729","pmid":"https://pubmed.ncbi.nlm.nih.gov/29806495"},"language":"en","primary_location":{"id":"doi:10.1080/21691401.2018.1476371","doi":"https://doi.org/10.1080/21691401.2018.1476371","is_oa":true,"landing_page_url":"https://doi.org/10.1080/21691401.2018.1476371","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/21691401.2018.1476371?needAccess=true&role=button","source":{"id":"https://openalex.org/S2489428960","display_name":"Artificial Cells Nanomedicine and Biotechnology","issn_l":"2169-1401","issn":["2169-1401","2169-141X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","medline","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Artificial Cells, Nanomedicine, and Biotechnology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.tandfonline.com/doi/pdf/10.1080/21691401.2018.1476371?needAccess=true&role=button","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074310229","display_name":"Enes G\u00fcnc\u00fcm","orcid":"https://orcid.org/0000-0001-8127-8730","observed_orcids":["https://orcid.org/0000-0001-8127-8730"]},"institutions":[{"id":"https://openalex.org/I45642913","display_name":"K\u0131r\u0131kkale University","ror":"https://ror.org/01zhwwf82","country_code":"TR","type":"education","lineage":["https://openalex.org/I45642913"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Enes G\u00fcnc\u00fcm","raw_affiliation_strings":["Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, K\u0131r\u0131kkale University","Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, K\u0131r\u0131kkale University, K\u0131r\u0131kkale, Turkey;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, K\u0131r\u0131kkale University","institution_ids":["https://openalex.org/I45642913"]},{"raw_affiliation_string":"Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, K\u0131r\u0131kkale University, K\u0131r\u0131kkale, Turkey;","institution_ids":["https://openalex.org/I45642913"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021779725","display_name":"Nuran I\u015f\u0131klan","orcid":"https://orcid.org/0000-0002-4051-6533","observed_orcids":["https://orcid.org/0000-0002-4051-6533"]},"institutions":[{"id":"https://openalex.org/I45642913","display_name":"K\u0131r\u0131kkale University","ror":"https://ror.org/01zhwwf82","country_code":"TR","type":"education","lineage":["https://openalex.org/I45642913"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Nuran I\u015f\u0131klan","raw_affiliation_strings":["Department of Chemistry, Faculty of Science and Arts, K\u0131r\u0131kkale University","Department of Chemistry, Faculty of Science and Arts, K\u0131r\u0131kkale University, K\u0131r\u0131kkale, Turkey;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Faculty of Science and Arts, K\u0131r\u0131kkale University","institution_ids":["https://openalex.org/I45642913"]},{"raw_affiliation_string":"Department of Chemistry, Faculty of Science and Arts, K\u0131r\u0131kkale University, K\u0131r\u0131kkale, Turkey;","institution_ids":["https://openalex.org/I45642913"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039670979","display_name":"Ceren Anla\u015f","orcid":"https://orcid.org/0000-0002-7997-016X","observed_orcids":["https://orcid.org/0000-0002-7997-016X"]},"institutions":[{"id":"https://openalex.org/I4210112471","display_name":"Istanbul University-Cerrahpa\u015fa","ror":"https://ror.org/01dzn5f42","country_code":"TR","type":"education","lineage":["https://openalex.org/I4210112471"]},{"id":"https://openalex.org/I67581229","display_name":"Istanbul University","ror":"https://ror.org/03a5qrr21","country_code":"TR","type":"education","lineage":["https://openalex.org/I67581229"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ceren Anla\u015f","raw_affiliation_strings":["Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Istanbul University","Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Istanbul University, Istanbul, Turkey;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Istanbul University","institution_ids":["https://openalex.org/I4210112471","https://openalex.org/I67581229"]},{"raw_affiliation_string":"Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Istanbul University, Istanbul, Turkey;","institution_ids":["https://openalex.org/I4210112471","https://openalex.org/I67581229"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020794159","display_name":"Nilg\u00fcn \u00dcnal","orcid":"https://orcid.org/0000-0002-0490-976X","observed_orcids":["https://orcid.org/0000-0002-0490-976X"]},"institutions":[{"id":"https://openalex.org/I45642913","display_name":"K\u0131r\u0131kkale University","ror":"https://ror.org/01zhwwf82","country_code":"TR","type":"education","lineage":["https://openalex.org/I45642913"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Nilg\u00fcn \u00dcnal","raw_affiliation_strings":["Department of Microbiology, Faculty of Veterinary Medicine, K\u0131r\u0131kkale University","Department of Microbiology, Faculty of Veterinary Medicine, K\u0131r\u0131kkale University, K\u0131r\u0131kkale, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Faculty of Veterinary Medicine, K\u0131r\u0131kkale University","institution_ids":["https://openalex.org/I45642913"]},{"raw_affiliation_string":"Department of Microbiology, Faculty of Veterinary Medicine, K\u0131r\u0131kkale University, K\u0131r\u0131kkale, Turkey","institution_ids":["https://openalex.org/I45642913"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000242228","display_name":"Elif Bulut","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I45642913","display_name":"K\u0131r\u0131kkale University","ror":"https://ror.org/01zhwwf82","country_code":"TR","type":"education","lineage":["https://openalex.org/I45642913"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Elif Bulut","raw_affiliation_strings":["Department of Microbiology, Faculty of Veterinary Medicine, K\u0131r\u0131kkale University","Department of Microbiology, Faculty of Veterinary Medicine, K\u0131r\u0131kkale University, K\u0131r\u0131kkale, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Faculty of Veterinary Medicine, K\u0131r\u0131kkale University","institution_ids":["https://openalex.org/I45642913"]},{"raw_affiliation_string":"Department of Microbiology, Faculty of Veterinary Medicine, K\u0131r\u0131kkale University, K\u0131r\u0131kkale, Turkey","institution_ids":["https://openalex.org/I45642913"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022397780","display_name":"T\u00fclay Bak\u0131rel","orcid":"https://orcid.org/0000-0001-5805-2178","observed_orcids":["https://orcid.org/0000-0001-5805-2178"]},"institutions":[{"id":"https://openalex.org/I4210112471","display_name":"Istanbul University-Cerrahpa\u015fa","ror":"https://ror.org/01dzn5f42","country_code":"TR","type":"education","lineage":["https://openalex.org/I4210112471"]},{"id":"https://openalex.org/I67581229","display_name":"Istanbul University","ror":"https://ror.org/03a5qrr21","country_code":"TR","type":"education","lineage":["https://openalex.org/I67581229"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"T\u00fclay Bak\u0131rel","raw_affiliation_strings":["Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Istanbul University","Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Istanbul University, Istanbul, Turkey;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Istanbul University","institution_ids":["https://openalex.org/I4210112471","https://openalex.org/I67581229"]},{"raw_affiliation_string":"Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Istanbul University, Istanbul, Turkey;","institution_ids":["https://openalex.org/I4210112471","https://openalex.org/I67581229"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5074310229"],"corresponding_institution_ids":["https://openalex.org/I45642913"],"apc_list":{"value":2085,"currency":"GBP","value_usd":2557},"apc_paid":null,"fwci":2.9693,"has_fulltext":true,"cited_by_count":73,"citation_normalized_percentile":{"value":0.91231733,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"46","issue":"sup2","first_page":"964","last_page":"973"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.7339000105857849,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.7339000105857849,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.2563000023365021,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amoxicillin","display_name":"amoxicillin","score":0.9929999709129333},{"id":"https://openalex.org/keywords/polymeric-nanoparticles","display_name":"polymeric nanoparticles","score":0.824999988079071},{"id":"https://openalex.org/keywords/polyvinyl-alcohol","display_name":"polyvinyl alcohol","score":0.890999972820282},{"id":"https://openalex.org/keywords/sodium-alginate","display_name":"sodium alginate","score":1.0},{"id":"https://openalex.org/keywords/sustained-release","display_name":"sustained drug release","score":0.8579999804496765},{"id":"https://openalex.org/keywords/controlled-release","display_name":"controlled release","score":0.8169999718666077},{"id":"https://openalex.org/keywords/glutaraldehyde-crosslinking","display_name":"glutaraldehyde crosslinking","score":0.890999972820282},{"id":"https://openalex.org/keywords/ph-sensitive-release","display_name":"pH-dependent release","score":0.781000018119812},{"id":"https://openalex.org/keywords/amorphous-drug","display_name":"amorphous drug","score":0.7319999933242798},{"id":"https://openalex.org/keywords/antibacterial-activity","display_name":"antibacterial activity","score":0.8920000195503235},{"id":"https://openalex.org/keywords/drug-delivery-systems","display_name":"drug delivery systems","score":0.7720000147819519},{"id":"https://openalex.org/keywords/minimum-inhibitory-concentration","display_name":"minimum inhibitory concentration","score":0.6890000104904175}],"concepts":[{"id":"https://openalex.org/C86181022","wikidata":"https://www.wikidata.org/wiki/Q196823","display_name":"Zeta potential","level":3,"score":0.7984440326690674},{"id":"https://openalex.org/C2780666587","wikidata":"https://www.wikidata.org/wiki/Q409591","display_name":"Vinyl alcohol","level":3,"score":0.7162250280380249},{"id":"https://openalex.org/C2777529624","wikidata":"https://www.wikidata.org/wiki/Q416475","display_name":"Glutaraldehyde","level":2,"score":0.6675302386283875},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.6516005992889404},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5999143719673157},{"id":"https://openalex.org/C187530423","wikidata":"https://www.wikidata.org/wiki/Q7140503","display_name":"Particle size","level":2,"score":0.5778071284294128},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.5129234790802002},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.48987239599227905},{"id":"https://openalex.org/C2779708577","wikidata":"https://www.wikidata.org/wiki/Q201928","display_name":"Amoxicillin","level":3,"score":0.48384276032447815},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.3383653163909912},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.2740691602230072},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2385895550251007},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.19594648480415344},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.10632520914077759},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.09418681263923645},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0732126235961914},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000464","descriptor_name":"Alginates","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000658","descriptor_name":"Amoxicillin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000658","descriptor_name":"Amoxicillin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D003692","descriptor_name":"Delayed-Action Preparations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010316","descriptor_name":"Particle Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011142","descriptor_name":"Polyvinyl Alcohol","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013211","descriptor_name":"Staphylococcus aureus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D053758","descriptor_name":"Nanoparticles","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1080/21691401.2018.1476371","doi":"https://doi.org/10.1080/21691401.2018.1476371","is_oa":true,"landing_page_url":"https://doi.org/10.1080/21691401.2018.1476371","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/21691401.2018.1476371?needAccess=true&role=button","source":{"id":"https://openalex.org/S2489428960","display_name":"Artificial Cells Nanomedicine and Biotechnology","issn_l":"2169-1401","issn":["2169-1401","2169-141X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","medline","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Artificial Cells, Nanomedicine, and Biotechnology","raw_type":"journal-article"},{"id":"pmid:29806495","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29806495","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Artificial cells, nanomedicine, and biotechnology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1080/21691401.2018.1476371","doi":"https://doi.org/10.1080/21691401.2018.1476371","is_oa":true,"landing_page_url":"https://doi.org/10.1080/21691401.2018.1476371","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/21691401.2018.1476371?needAccess=true&role=button","source":{"id":"https://openalex.org/S2489428960","display_name":"Artificial Cells Nanomedicine and Biotechnology","issn_l":"2169-1401","issn":["2169-1401","2169-141X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","medline","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Artificial Cells, Nanomedicine, and Biotechnology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9074000120162964}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4351122793","display_name":null,"funder_award_id":"44188","funder_id":"https://openalex.org/F4320322277","funder_display_name":"Bilimsel Ara\u015ftirma Projeleri Birimi, Istanbul \u00dcniversitesi"}],"funders":[{"id":"https://openalex.org/F4320322277","display_name":"Bilimsel Ara\u015ftirma Projeleri Birimi, Istanbul \u00dcniversitesi","ror":"https://ror.org/03a5qrr21"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2804299729.pdf","grobid_xml":"https://content.openalex.org/works/W2804299729.grobid-xml"},"referenced_works_count":59,"referenced_works":["https://openalex.org/W1568143123","https://openalex.org/W1591778978","https://openalex.org/W1967275048","https://openalex.org/W1967686679","https://openalex.org/W1975710258","https://openalex.org/W1976245890","https://openalex.org/W1977711966","https://openalex.org/W1978994329","https://openalex.org/W1987144399","https://openalex.org/W1991092566","https://openalex.org/W2002269770","https://openalex.org/W2004304955","https://openalex.org/W2007524359","https://openalex.org/W2007755698","https://openalex.org/W2010312818","https://openalex.org/W2011115123","https://openalex.org/W2016031848","https://openalex.org/W2016149234","https://openalex.org/W2016779268","https://openalex.org/W2017802048","https://openalex.org/W2018250782","https://openalex.org/W2036444454","https://openalex.org/W2038718342","https://openalex.org/W2041698490","https://openalex.org/W2046564987","https://openalex.org/W2050181086","https://openalex.org/W2053925222","https://openalex.org/W2061766301","https://openalex.org/W2063144941","https://openalex.org/W2068840283","https://openalex.org/W2071777686","https://openalex.org/W2079555182","https://openalex.org/W2080279161","https://openalex.org/W2083479049","https://openalex.org/W2088743004","https://openalex.org/W2092383445","https://openalex.org/W2099458391","https://openalex.org/W2115632352","https://openalex.org/W2120782718","https://openalex.org/W2120858584","https://openalex.org/W2122582038","https://openalex.org/W2129065348","https://openalex.org/W2131860317","https://openalex.org/W2153920286","https://openalex.org/W2292141861","https://openalex.org/W2321025545","https://openalex.org/W2329247577","https://openalex.org/W2336156617","https://openalex.org/W2339534049","https://openalex.org/W2398547733","https://openalex.org/W2443963820","https://openalex.org/W2473707833","https://openalex.org/W2486374005","https://openalex.org/W2523243233","https://openalex.org/W2581368247","https://openalex.org/W2604590374","https://openalex.org/W2621599651","https://openalex.org/W2750556669","https://openalex.org/W3113585841"],"related_works":["https://openalex.org/W4319656983","https://openalex.org/W2963167878","https://openalex.org/W296107621","https://openalex.org/W2014682822","https://openalex.org/W2794551698","https://openalex.org/W4400616904","https://openalex.org/W4296137286","https://openalex.org/W1976303009","https://openalex.org/W2779964955","https://openalex.org/W4408480536"],"abstract_inverted_index":{"In":[0,91],"this":[1,153],"study,":[2],"amoxicillin":[3],"(AMO)-loaded":[4],"poly(vinyl":[5],"alcohol)/sodium":[6],"alginate":[7],"(PVA/NaAlg)":[8],"nanoparticles":[9,24,116,123,171],"were":[10,25,41,89],"prepared":[11],"as":[12],"a":[13,97,174],"polymer-based":[14],"controlled":[15,98],"release":[16,87,94,103],"system.":[17],"The":[18,37,68,136,146],"physicochemical":[19],"properties":[20],"of":[21,70,114,139,152,162],"the":[22,43,82,119,122,133,140,156,169],"obtained":[23],"investigated":[26],"by":[27],"XRD,":[28],"DSC/TGA,":[29],"particle":[30,39],"size":[31],"analyses":[32],"and":[33,81,99,111],"zeta":[34,56],"potential":[35,57],"measurements.":[36],"average":[38],"sizes":[40],"in":[42,121,125],"range":[44],"from":[45,59],"336.3":[46],"\u00b1":[47,51,61,65],"25.66":[48],"to":[49,63,78],"558.3":[50],"31.39":[52],"nm":[53],"with":[54,104,160],"negative":[55],"values":[58,151],"-41.86":[60],"0.55":[62],"-47.3":[64],"2.76":[66],"mV.":[67],"influences":[69],"PVA/NaAlg":[71],"ratio,":[72],"span":[73],"80":[74],"concentration,":[75],"exposure":[76],"time":[77],"glutaraldehyde":[79],"(GA)":[80],"drug/polymer":[83],"ratio":[84],"on":[85],"AMO":[86,102],"profiles":[88],"evaluated.":[90],"vitro":[92],"drug":[93,120,177],"studies":[95],"showed":[96],"pH":[100],"dependent":[101],"an":[105],"initial":[106],"burst":[107],"effect.":[108],"XRD":[109],"patterns":[110],"DSC":[112],"thermograms":[113],"AMO-loaded":[115],"revealed":[117],"that":[118,161,168],"was":[124,129,143],"amorphous":[126],"form,":[127],"which":[128],"more":[130],"stable":[131],"than":[132],"crystalline":[134],"form.":[135],"antibacterial":[137,158],"activity":[138,159],"optimal":[141],"formulation":[142,154],"also":[144],"investigated.":[145],"minimum":[147],"inhibitory":[148],"concentration":[149],"(MIC)":[150],"had":[155],"comparable":[157],"pure":[163],"AMO.":[164,181],"These":[165],"results":[166],"indicate":[167],"developed":[170],"could":[172],"be":[173],"promising":[175],"candidate":[176],"delivery":[178],"system":[179],"for":[180]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":13},{"year":2019,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-06-01T00:00:00"}
