{"id":"https://openalex.org/W2803916853","doi":"https://doi.org/10.1017/s0007114518000855","title":"The influence of juicing on the appearance of blueberry metabolites 2 h after consumption: a metabolite profiling approach","display_name":"The influence of juicing on the appearance of blueberry metabolites 2 h after consumption: a metabolite profiling approach","publication_year":2018,"publication_date":"2018-05-17","ids":{"openalex":"https://openalex.org/W2803916853","doi":"https://doi.org/10.1017/s0007114518000855","mag":"2803916853","pmid":"https://pubmed.ncbi.nlm.nih.gov/29770756"},"language":"en","primary_location":{"id":"doi:10.1017/s0007114518000855","doi":"https://doi.org/10.1017/s0007114518000855","is_oa":true,"landing_page_url":"https://doi.org/10.1017/s0007114518000855","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/0B60143E79B6ACBC0C8F6F8F8C3656AF/S0007114518000855a.pdf/div-class-title-the-influence-of-juicing-on-the-appearance-of-blueberry-metabolites-2-h-after-consumption-a-metabolite-profiling-approach-div.pdf","source":{"id":"https://openalex.org/S4218381","display_name":"British Journal Of Nutrition","issn_l":"0007-1145","issn":["0007-1145","1475-2662"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Nutrition","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/0B60143E79B6ACBC0C8F6F8F8C3656AF/S0007114518000855a.pdf/div-class-title-the-influence-of-juicing-on-the-appearance-of-blueberry-metabolites-2-h-after-consumption-a-metabolite-profiling-approach-div.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085970170","display_name":"Swen Langer","orcid":"https://orcid.org/0000-0002-9684-1167","observed_orcids":["https://orcid.org/0000-0002-9684-1167"]},"institutions":[{"id":"https://openalex.org/I32394136","display_name":"Northumbria University","ror":"https://ror.org/049e6bc10","country_code":"GB","type":"education","lineage":["https://openalex.org/I32394136"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Swen Langer","raw_affiliation_strings":["Department of Applied Sciences, Faculty of Health and Life Sciences, Ellison Building, Northumbria University, Newcastle Upon Tyne, Tyne and Wear NE1 7ST, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Applied Sciences, Faculty of Health and Life Sciences, Ellison Building, Northumbria University, Newcastle Upon Tyne, Tyne and Wear NE1 7ST, UK","institution_ids":["https://openalex.org/I32394136"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016498747","display_name":"Aileen Kennel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32394136","display_name":"Northumbria University","ror":"https://ror.org/049e6bc10","country_code":"GB","type":"education","lineage":["https://openalex.org/I32394136"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Aileen Kennel","raw_affiliation_strings":["Department of Applied Sciences, Faculty of Health and Life Sciences, Ellison Building, Northumbria University, Newcastle Upon Tyne, Tyne and Wear NE1 7ST, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Applied Sciences, Faculty of Health and Life Sciences, Ellison Building, Northumbria University, Newcastle Upon Tyne, Tyne and Wear NE1 7ST, UK","institution_ids":["https://openalex.org/I32394136"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045873156","display_name":"John K. Lodge","orcid":"https://orcid.org/0000-0001-6014-4952","observed_orcids":["https://orcid.org/0000-0001-6014-4952"]},"institutions":[{"id":"https://openalex.org/I32394136","display_name":"Northumbria University","ror":"https://ror.org/049e6bc10","country_code":"GB","type":"education","lineage":["https://openalex.org/I32394136"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"John K. Lodge","raw_affiliation_strings":["Department of Applied Sciences, Faculty of Health and Life Sciences, Ellison Building, Northumbria University, Newcastle Upon Tyne, Tyne and Wear NE1 7ST, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Applied Sciences, Faculty of Health and Life Sciences, Ellison Building, Northumbria University, Newcastle Upon Tyne, Tyne and Wear NE1 7ST, UK","institution_ids":["https://openalex.org/I32394136"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5045873156"],"corresponding_institution_ids":["https://openalex.org/I32394136"],"apc_list":{"value":3550,"currency":"USD","value_usd":3550},"apc_paid":null,"fwci":0.9874,"has_fulltext":true,"cited_by_count":24,"citation_normalized_percentile":{"value":0.70590392,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"119","issue":"11","first_page":"1233","last_page":"1244"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12638","display_name":"Pomegranate: compositions and health benefits","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/blueberry","display_name":"blueberry","score":0.8579999804496765},{"id":"https://openalex.org/keywords/bioavailability","display_name":"bioavailability","score":0.8479999899864197},{"id":"https://openalex.org/keywords/metabolic-profiling","display_name":"metabolite profiling","score":0.7580000162124634},{"id":"https://openalex.org/keywords/urinary-metabolites","display_name":"urinary metabolites","score":0.8349999785423279},{"id":"https://openalex.org/keywords/plasma-metabolites","display_name":"plasma metabolites","score":0.9879999756813049},{"id":"https://openalex.org/keywords/phenolic-metabolites","display_name":"phenolic metabolites","score":0.8809999823570251},{"id":"https://openalex.org/keywords/ferulic-acid","display_name":"ferulic acid","score":0.8650000095367432},{"id":"https://openalex.org/keywords/caffeic-acid","display_name":"caffeic acid","score":0.9909999966621399},{"id":"https://openalex.org/keywords/glucuronide-conjugates","display_name":"glucuronide conjugates","score":0.7149999737739563},{"id":"https://openalex.org/keywords/sulfate-conjugates","display_name":"sulfate conjugates","score":0.7229999899864197}],"concepts":[{"id":"https://openalex.org/C2777477808","wikidata":"https://www.wikidata.org/wiki/Q407595","display_name":"Metabolite","level":2,"score":0.8903447389602661},{"id":"https://openalex.org/C21565614","wikidata":"https://www.wikidata.org/wiki/Q12149006","display_name":"Metabolomics","level":2,"score":0.6822715401649475},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6236813068389893},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.5586519837379456},{"id":"https://openalex.org/C181389837","wikidata":"https://www.wikidata.org/wiki/Q461809","display_name":"Bioavailability","level":2,"score":0.5359047055244446},{"id":"https://openalex.org/C2780026642","wikidata":"https://www.wikidata.org/wiki/Q40924","display_name":"Urine","level":2,"score":0.5312801599502563},{"id":"https://openalex.org/C196235758","wikidata":"https://www.wikidata.org/wiki/Q3333419","display_name":"Primary metabolite","level":3,"score":0.4331561326980591},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.2861875593662262},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22283241152763367},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.20544546842575073},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.14029461145401}],"mesh":[{"descriptor_ui":"D000067030","descriptor_name":"Fruit and Vegetable Juices","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005511","descriptor_name":"Food Handling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005638","descriptor_name":"Fruit","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010636","descriptor_name":"Phenols","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D016002","descriptor_name":"Discriminant Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016018","descriptor_name":"Least-Squares Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018592","descriptor_name":"Cross-Over Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029798","descriptor_name":"Blueberry Plants","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1017/s0007114518000855","doi":"https://doi.org/10.1017/s0007114518000855","is_oa":true,"landing_page_url":"https://doi.org/10.1017/s0007114518000855","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/0B60143E79B6ACBC0C8F6F8F8C3656AF/S0007114518000855a.pdf/div-class-title-the-influence-of-juicing-on-the-appearance-of-blueberry-metabolites-2-h-after-consumption-a-metabolite-profiling-approach-div.pdf","source":{"id":"https://openalex.org/S4218381","display_name":"British Journal Of Nutrition","issn_l":"0007-1145","issn":["0007-1145","1475-2662"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Nutrition","raw_type":"journal-article"},{"id":"pmid:29770756","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29770756","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The British journal of nutrition","raw_type":"Journal Article"},{"id":"pmh:oai:nrl.northumbria.ac.uk:33910","doi":null,"is_oa":false,"landing_page_url":"http://nrl.northumbria.ac.uk/id/eprint/33910/1/Langer%20et%20al%20-%20The%20influence%20of%20juicing%20on%20the%20appearance%20of%20blueberry%20metabolites.docx","pdf_url":null,"source":{"id":"https://openalex.org/S4306401884","display_name":"Northumbria Research Link (Northumbria University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I32394136","host_organization_name":"Northumbria University","host_organization_lineage":["https://openalex.org/I32394136"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1017/s0007114518000855","doi":"https://doi.org/10.1017/s0007114518000855","is_oa":true,"landing_page_url":"https://doi.org/10.1017/s0007114518000855","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/0B60143E79B6ACBC0C8F6F8F8C3656AF/S0007114518000855a.pdf/div-class-title-the-influence-of-juicing-on-the-appearance-of-blueberry-metabolites-2-h-after-consumption-a-metabolite-profiling-approach-div.pdf","source":{"id":"https://openalex.org/S4218381","display_name":"British Journal Of Nutrition","issn_l":"0007-1145","issn":["0007-1145","1475-2662"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Nutrition","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Zero hunger","score":0.6735000014305115,"id":"https://metadata.un.org/sdg/2"},{"display_name":"Good health and well-being","score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320311737","display_name":"Northumbria University","ror":"https://ror.org/049e6bc10"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2803916853.pdf","grobid_xml":"https://content.openalex.org/works/W2803916853.grobid-xml"},"referenced_works_count":57,"referenced_works":["https://openalex.org/W910037980","https://openalex.org/W1874298169","https://openalex.org/W1910630333","https://openalex.org/W1963786553","https://openalex.org/W1963871800","https://openalex.org/W1971886741","https://openalex.org/W1973865418","https://openalex.org/W1985301815","https://openalex.org/W1986366688","https://openalex.org/W1992132148","https://openalex.org/W1999386633","https://openalex.org/W2002738268","https://openalex.org/W2010371704","https://openalex.org/W2035715038","https://openalex.org/W2048912169","https://openalex.org/W2057284307","https://openalex.org/W2065743937","https://openalex.org/W2068838394","https://openalex.org/W2079533152","https://openalex.org/W2082348062","https://openalex.org/W2089220405","https://openalex.org/W2092074137","https://openalex.org/W2092083822","https://openalex.org/W2096891019","https://openalex.org/W2101061058","https://openalex.org/W2110263387","https://openalex.org/W2111844468","https://openalex.org/W2112045685","https://openalex.org/W2115581755","https://openalex.org/W2118395519","https://openalex.org/W2118756389","https://openalex.org/W2119331100","https://openalex.org/W2120026749","https://openalex.org/W2122276505","https://openalex.org/W2122970990","https://openalex.org/W2123355142","https://openalex.org/W2142885994","https://openalex.org/W2143751153","https://openalex.org/W2146376359","https://openalex.org/W2147133145","https://openalex.org/W2151300123","https://openalex.org/W2152252699","https://openalex.org/W2153851030","https://openalex.org/W2155530251","https://openalex.org/W2155858980","https://openalex.org/W2158049381","https://openalex.org/W2162885747","https://openalex.org/W2163481817","https://openalex.org/W2262960861","https://openalex.org/W2304492464","https://openalex.org/W2312881855","https://openalex.org/W2325900732","https://openalex.org/W2402945316","https://openalex.org/W2558194637","https://openalex.org/W2604549131","https://openalex.org/W2605109562","https://openalex.org/W4237898279"],"related_works":["https://openalex.org/W2615606555","https://openalex.org/W2626059277","https://openalex.org/W2511927913","https://openalex.org/W2591754043","https://openalex.org/W2605109562","https://openalex.org/W3005704716","https://openalex.org/W2990546045","https://openalex.org/W2949290975","https://openalex.org/W2865167933","https://openalex.org/W2312510121"],"abstract_inverted_index":{"The":[0],"consumption":[1,208],"of":[2,10,30,49,57,63,76,119,135,174,179,199,209,217],"berries":[3],"has":[4,34],"been":[5],"linked":[6],"to":[7,36,42,53,188],"decreased":[8],"risk":[9],"degenerative":[11],"disease.":[12],"Berries":[13],"are":[14],"regularly":[15],"processed":[16],"into":[17],"juices.":[18],"It":[19],"is":[20],"largely":[21],"unknown":[22],"how":[23],"the":[24,28,47,55,60,81,248],"juicing":[25,58],"process":[26],"affects":[27],"bioavailability":[29],"metabolites.":[31],"As":[32],"metabolomics":[33],"shown":[35],"be":[37],"a":[38,100,214],"valuable":[39],"nutritional":[40],"tool":[41],"study":[43,51],"global":[44],"metabolite":[45,105,240],"differences,":[46],"aim":[48],"this":[50,246],"was":[52,247],"investigate":[54],"effect":[56],"on":[59],"relative":[61],"appearance":[62],"blueberry":[64,127,145,204],"metabolites":[65,178,186,221],"in":[66,99,148,213,222,237],"humans":[67],"using":[68,107],"metabolomics.":[69],"Nine":[70],"healthy":[71],"subjects":[72],"consumed":[73],"250":[74],"g":[75],"fresh":[77],"blueberries":[78,211,235],"either":[79],"as":[80],"whole":[82,144,203,210,232],"fruit":[83],"or":[84,191],"after":[85,97,170,202,229],"juicing,":[86],"and":[87,90,94,109,160,181,193,219,224,233],"provided":[88],"blood":[89],"urine":[91,225],"samples":[92,137,226],"before":[93],"2":[95,227,243],"h":[96,228],"intake":[98],"cross-over":[101],"design.":[102],"Samples":[103],"underwent":[104],"profiling":[106],"LCMS,":[108],"data":[110],"were":[111,123,152,167,198],"mined":[112],"with":[113,156],"multivariate":[114],"analysis.":[115],"Overall,":[116],"<12":[117],"%":[118],"all":[120],"ions":[121,150],"detected":[122],"significantly":[124,153,168],"influenced":[125],"by":[126],"treatment":[128,146,158],"(P<0\u00b705).":[129],"Partial":[130],"least-squared":[131],"discriminant":[132],"analysis":[133],"models":[134],"post-treatment":[136],"revealed":[138],"good":[139],"discrimination.":[140],"In":[141,206],"urinary":[142],"samples,":[143],"resulted":[147,212,236],"108":[149],"that":[151],"higher":[154,169,200,215],"compared":[155],"juiced":[157,171,234],"(positive":[159],"negative":[161],"mode":[162],"combined),":[163],"whereas":[164],"only":[165,249],"eight":[166],"treatment.":[172,205],"Examples":[173],"putative":[175],"annotations":[176],"included":[177],"ferulic":[180],"caffeic":[182],"acids,":[183],"several":[184],"phenolic":[185,218],"conjugated":[187],"sulphate,":[189],"glycoside":[190],"glucuronide":[192],"fatty":[194],"acyl":[195],"derivatives,":[196],"which":[197],"intensity":[201],"conclusion,":[207],"range":[216],"other":[220],"plasma":[223],"consumption.":[230],"Both":[231],"very":[238],"similar":[239],"profiles":[241],"at":[242],"h,":[244],"although":[245],"time":[250],"point":[251],"measured.":[252]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-06-01T00:00:00"}