{"id":"https://openalex.org/W2803727503","doi":"https://doi.org/10.1186/s12936-018-2348-8","title":"Emergence of knock-down resistance in the Anopheles gambiae complex in the Upper River Region, The Gambia, and its relationship with malaria infection in children","display_name":"Emergence of knock-down resistance in the Anopheles gambiae complex in the Upper River Region, The Gambia, and its relationship with malaria infection in children","publication_year":2018,"publication_date":"2018-05-18","ids":{"openalex":"https://openalex.org/W2803727503","doi":"https://doi.org/10.1186/s12936-018-2348-8","mag":"2803727503","pmid":"https://pubmed.ncbi.nlm.nih.gov/29776361","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5960171"},"language":"en","primary_location":{"id":"doi:10.1186/s12936-018-2348-8","doi":"https://doi.org/10.1186/s12936-018-2348-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12936-018-2348-8","pdf_url":"https://malariajournal.biomedcentral.com/track/pdf/10.1186/s12936-018-2348-8","source":{"id":"https://openalex.org/S93003929","display_name":"Malaria Journal","issn_l":"1475-2875","issn":["1475-2875"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Malaria Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://malariajournal.biomedcentral.com/track/pdf/10.1186/s12936-018-2348-8","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019179797","display_name":"Anne L. Wilson","orcid":"https://orcid.org/0000-0001-7387-353X","observed_orcids":["https://orcid.org/0000-0001-7387-353X","https://orcid.org/0000-0003-2855-4198"]},"institutions":[{"id":"https://openalex.org/I190082696","display_name":"Durham University","ror":"https://ror.org/01v29qb04","country_code":"GB","type":"education","lineage":["https://openalex.org/I190082696"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Anne L. Wilson","raw_affiliation_strings":["Durham University, Durham, UK. awilson28@gmail.com","Durham University, Durham, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Durham University, Durham, UK. awilson28@gmail.com","institution_ids":["https://openalex.org/I190082696"]},{"raw_affiliation_string":"Durham University, Durham, UK","institution_ids":["https://openalex.org/I190082696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111928132","display_name":"Margaret Pinder","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I190082696","display_name":"Durham University","ror":"https://ror.org/01v29qb04","country_code":"GB","type":"education","lineage":["https://openalex.org/I190082696"]},{"id":"https://openalex.org/I4210116687","display_name":"MRC Unit the Gambia","ror":"https://ror.org/025wfj672","country_code":"GM","type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210087105","https://openalex.org/I4210089966","https://openalex.org/I4210116687","https://openalex.org/I90344618"]}],"countries":["GB","GM"],"is_corresponding":false,"raw_author_name":"Margaret Pinder","raw_affiliation_strings":["Durham University, Durham, UK","Medical Research Council Unit The Gambia at the London School of Hygiene & Tropical Medicine, Banjul, The Gambia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Durham University, Durham, UK","institution_ids":["https://openalex.org/I190082696"]},{"raw_affiliation_string":"Medical Research Council Unit The Gambia at the London School of Hygiene & Tropical Medicine, Banjul, The Gambia","institution_ids":["https://openalex.org/I4210116687"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080399165","display_name":"John Bradley","orcid":"https://orcid.org/0000-0002-9449-4608","observed_orcids":["https://orcid.org/0000-0002-9449-4608"]},"institutions":[{"id":"https://openalex.org/I4210089966","display_name":"London School of Hygiene & Tropical Medicine","ror":"https://ror.org/00a0jsq62","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210089966"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"John Bradley","raw_affiliation_strings":["London School of Hygiene and Tropical Medicine, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"London School of Hygiene and Tropical Medicine, London, UK","institution_ids":["https://openalex.org/I4210089966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036500781","display_name":"Martin J. Donnelly","orcid":"https://orcid.org/0000-0001-5218-1497","observed_orcids":["https://orcid.org/0000-0001-5218-1497"]},"institutions":[{"id":"https://openalex.org/I194839184","display_name":"Liverpool School of Tropical Medicine","ror":"https://ror.org/03svjbs84","country_code":"GB","type":"funder","lineage":["https://openalex.org/I194839184"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Martin J. Donnelly","raw_affiliation_strings":["Liverpool School of Tropical Medicine, Liverpool, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Liverpool School of Tropical Medicine, Liverpool, UK","institution_ids":["https://openalex.org/I194839184"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059722106","display_name":"Majidah Hamid\u2010Adiamoh","orcid":"https://orcid.org/0000-0002-0101-5445","observed_orcids":["https://orcid.org/0000-0002-0101-5445"]},"institutions":[{"id":"https://openalex.org/I4210116687","display_name":"MRC Unit the Gambia","ror":"https://ror.org/025wfj672","country_code":"GM","type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210087105","https://openalex.org/I4210089966","https://openalex.org/I4210116687","https://openalex.org/I90344618"]}],"countries":["GM"],"is_corresponding":false,"raw_author_name":"Majidah Hamid-Adiamoh","raw_affiliation_strings":["Medical Research Council Unit The Gambia at the London School of Hygiene & Tropical Medicine, Banjul, The Gambia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Research Council Unit The Gambia at the London School of Hygiene & Tropical Medicine, Banjul, The Gambia","institution_ids":["https://openalex.org/I4210116687"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027320375","display_name":"Lamin B. S. Jarju","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lamin B. S. Jarju","raw_affiliation_strings":["National Malaria Control Programme, Banjul, The Gambia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Malaria Control Programme, Banjul, The Gambia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008254527","display_name":"Musa Jawara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210116687","display_name":"MRC Unit the Gambia","ror":"https://ror.org/025wfj672","country_code":"GM","type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210087105","https://openalex.org/I4210089966","https://openalex.org/I4210116687","https://openalex.org/I90344618"]}],"countries":["GM"],"is_corresponding":false,"raw_author_name":"Musa Jawara","raw_affiliation_strings":["Medical Research Council Unit The Gambia at the London School of Hygiene & Tropical Medicine, Banjul, The Gambia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Research Council Unit The Gambia at the London School of Hygiene & Tropical Medicine, Banjul, The Gambia","institution_ids":["https://openalex.org/I4210116687"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060627708","display_name":"David J. Jeffries","orcid":"https://orcid.org/0000-0001-7471-1364","observed_orcids":["https://orcid.org/0000-0001-7471-1364"]},"institutions":[{"id":"https://openalex.org/I4210116687","display_name":"MRC Unit the Gambia","ror":"https://ror.org/025wfj672","country_code":"GM","type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210087105","https://openalex.org/I4210089966","https://openalex.org/I4210116687","https://openalex.org/I90344618"]}],"countries":["GM"],"is_corresponding":false,"raw_author_name":"David Jeffries","raw_affiliation_strings":["Medical Research Council Unit The Gambia at the London School of Hygiene & Tropical Medicine, Banjul, The Gambia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Research Council Unit The Gambia at the London School of Hygiene & Tropical Medicine, Banjul, The Gambia","institution_ids":["https://openalex.org/I4210116687"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059605855","display_name":"Ballah Kandeh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ballah Kandeh","raw_affiliation_strings":["National Malaria Control Programme, Banjul, The Gambia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Malaria Control Programme, Banjul, The Gambia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056150507","display_name":"Emily J. Rippon","orcid":"https://orcid.org/0000-0003-3407-4959","observed_orcids":["https://orcid.org/0000-0003-3407-4959"]},"institutions":[{"id":"https://openalex.org/I194839184","display_name":"Liverpool School of Tropical Medicine","ror":"https://ror.org/03svjbs84","country_code":"GB","type":"funder","lineage":["https://openalex.org/I194839184"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Emily J. Rippon","raw_affiliation_strings":["Liverpool School of Tropical Medicine, Liverpool, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Liverpool School of Tropical Medicine, Liverpool, UK","institution_ids":["https://openalex.org/I194839184"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040429524","display_name":"Kolawole Salami","orcid":"https://orcid.org/0000-0003-3649-6709","observed_orcids":["https://orcid.org/0000-0003-3649-6709"]},"institutions":[{"id":"https://openalex.org/I4210116687","display_name":"MRC Unit the Gambia","ror":"https://ror.org/025wfj672","country_code":"GM","type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210087105","https://openalex.org/I4210089966","https://openalex.org/I4210116687","https://openalex.org/I90344618"]}],"countries":["GM"],"is_corresponding":false,"raw_author_name":"Kolawole Salami","raw_affiliation_strings":["Medical Research Council Unit The Gambia at the London School of Hygiene & Tropical Medicine, Banjul, The Gambia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Research Council Unit The Gambia at the London School of Hygiene & Tropical Medicine, Banjul, The Gambia","institution_ids":["https://openalex.org/I4210116687"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033754121","display_name":"Umberto D\u2019Alessandro","orcid":"https://orcid.org/0000-0001-6341-5009","observed_orcids":["https://orcid.org/0000-0001-6341-5009"]},"institutions":[{"id":"https://openalex.org/I4210089966","display_name":"London School of Hygiene & Tropical Medicine","ror":"https://ror.org/00a0jsq62","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210089966"]},{"id":"https://openalex.org/I4210116687","display_name":"MRC Unit the Gambia","ror":"https://ror.org/025wfj672","country_code":"GM","type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210087105","https://openalex.org/I4210089966","https://openalex.org/I4210116687","https://openalex.org/I90344618"]}],"countries":["GB","GM"],"is_corresponding":false,"raw_author_name":"Umberto D\u2019Alessandro","raw_affiliation_strings":["London School of Hygiene and Tropical Medicine, London, UK","Medical Research Council Unit The Gambia at the London School of Hygiene & Tropical Medicine, Banjul, The Gambia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"London School of Hygiene and Tropical Medicine, London, UK","institution_ids":["https://openalex.org/I4210089966"]},{"raw_affiliation_string":"Medical Research Council Unit The Gambia at the London School of Hygiene & Tropical Medicine, Banjul, The Gambia","institution_ids":["https://openalex.org/I4210116687"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043164969","display_name":"Steve W. Lindsay","orcid":"https://orcid.org/0000-0002-3461-9050","observed_orcids":["https://orcid.org/0000-0002-3461-9050"]},"institutions":[{"id":"https://openalex.org/I190082696","display_name":"Durham University","ror":"https://ror.org/01v29qb04","country_code":"GB","type":"education","lineage":["https://openalex.org/I190082696"]},{"id":"https://openalex.org/I4210089966","display_name":"London School of Hygiene & Tropical Medicine","ror":"https://ror.org/00a0jsq62","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210089966"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Steven W. Lindsay","raw_affiliation_strings":["Durham University, Durham, UK","London School of Hygiene and Tropical Medicine, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Durham University, Durham, UK","institution_ids":["https://openalex.org/I190082696"]},{"raw_affiliation_string":"London School of Hygiene and Tropical Medicine, London, UK","institution_ids":["https://openalex.org/I4210089966"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5019179797"],"corresponding_institution_ids":["https://openalex.org/I190082696"],"apc_list":{"value":2890,"currency":"USD","value_usd":2890},"apc_paid":{"value":1951,"currency":"EUR","value_usd":2104},"fwci":1.9032,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.85049691,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"17","issue":"1","first_page":"205","last_page":"205"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11075","display_name":"Insect Resistance and Genetics","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14053","display_name":"Dengue and Mosquito Control Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3312","display_name":"Sociology and Political Science"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/knockdown-resistance","display_name":"knockdown resistance","score":0.9169999957084656},{"id":"https://openalex.org/keywords/anopheles-gambiae-s-l","display_name":"Anopheles gambiae s.l.","score":0.7950000166893005},{"id":"https://openalex.org/keywords/pyrethroid-resistance","display_name":"pyrethroid resistance","score":0.7900000214576721},{"id":"https://openalex.org/keywords/organochlorine-resistance","display_name":"organochlorine resistance","score":0.859000027179718},{"id":"https://openalex.org/keywords/voltage-gated-sodium-channels","display_name":"voltage-gated sodium channels","score":0.9359999895095825},{"id":"https://openalex.org/keywords/pediatric-malaria","display_name":"pediatric malaria","score":0.5289999842643738},{"id":"https://openalex.org/keywords/malaria-transmission","display_name":"malaria transmission","score":0.492000013589859},{"id":"https://openalex.org/keywords/anopheles-arabiensis","display_name":"Anopheles arabiensis","score":0.8579999804496765},{"id":"https://openalex.org/keywords/anopheles-coluzzii","display_name":"Anopheles coluzzii","score":1.0},{"id":"https://openalex.org/keywords/anopheles-gambiae-sensu-stricto","display_name":"Anopheles gambiae sensu stricto","score":0.9739999771118164},{"id":"https://openalex.org/keywords/indoor-residual-spraying","display_name":"indoor residual spraying","score":0.718999981880188},{"id":"https://openalex.org/keywords/insecticide-resistance","display_name":"insecticide resistance","score":0.5040000081062317}],"concepts":[{"id":"https://openalex.org/C2776802408","wikidata":"https://www.wikidata.org/wiki/Q135237","display_name":"Anopheles gambiae","level":3,"score":0.9338376522064209},{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.7472251057624817},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.696804404258728},{"id":"https://openalex.org/C190612196","wikidata":"https://www.wikidata.org/wiki/Q180502","display_name":"Parasitology","level":2,"score":0.5463138818740845},{"id":"https://openalex.org/C2780346216","wikidata":"https://www.wikidata.org/wiki/Q6026475","display_name":"Indoor residual spraying","level":5,"score":0.47243818640708923},{"id":"https://openalex.org/C2781375639","wikidata":"https://www.wikidata.org/wiki/Q158597","display_name":"Anopheles","level":3,"score":0.44339966773986816},{"id":"https://openalex.org/C2778371730","wikidata":"https://www.wikidata.org/wiki/Q311383","display_name":"Plasmodium falciparum","level":3,"score":0.4430009722709656},{"id":"https://openalex.org/C42972112","wikidata":"https://www.wikidata.org/wiki/Q170201","display_name":"Veterinary medicine","level":1,"score":0.42532920837402344},{"id":"https://openalex.org/C2780211283","wikidata":"https://www.wikidata.org/wiki/Q6422844","display_name":"Knockdown resistance","level":5,"score":0.4106563329696655},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.37259817123413086},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.33002275228500366},{"id":"https://openalex.org/C90856448","wikidata":"https://www.wikidata.org/wiki/Q431","display_name":"Zoology","level":1,"score":0.2383754551410675},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.22899630665779114},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2093719244003296},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1874999701976776},{"id":"https://openalex.org/C2776035571","wikidata":"https://www.wikidata.org/wiki/Q745766","display_name":"Pyrethroid","level":3,"score":0.11908701062202454},{"id":"https://openalex.org/C161176658","wikidata":"https://www.wikidata.org/wiki/Q131656","display_name":"Pesticide","level":2,"score":0.08302012085914612},{"id":"https://openalex.org/C2776120307","wikidata":"https://www.wikidata.org/wiki/Q426921","display_name":"Artemisinin","level":4,"score":0.0},{"id":"https://openalex.org/C2778635518","wikidata":"https://www.wikidata.org/wiki/Q61641151","display_name":"Cyfluthrin","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000852","descriptor_name":"Anopheles","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005714","descriptor_name":"Gambia","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007305","descriptor_name":"Insecticide Resistance","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D007306","descriptor_name":"Insecticides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D008288","descriptor_name":"Malaria","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D008288","descriptor_name":"Malaria","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019476","descriptor_name":"Insect Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D019476","descriptor_name":"Insect Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":11,"locations":[{"id":"doi:10.1186/s12936-018-2348-8","doi":"https://doi.org/10.1186/s12936-018-2348-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12936-018-2348-8","pdf_url":"https://malariajournal.biomedcentral.com/track/pdf/10.1186/s12936-018-2348-8","source":{"id":"https://openalex.org/S93003929","display_name":"Malaria Journal","issn_l":"1475-2875","issn":["1475-2875"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Malaria Journal","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4920434","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5960171","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5960171","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5960171","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Malar J","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5992667","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5992667","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Malar J","raw_type":"Text"},{"id":"pmid:29776361","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29776361","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Malaria journal","raw_type":"Journal Article"},{"id":"pmid:29879981","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29879981","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Malaria journal","raw_type":"Journal Article"},{"id":"pmh:oai:archive.lstmed.ac.uk:8705","doi":null,"is_oa":false,"landing_page_url":"https://archive.lstmed.ac.uk/8705/1/malaria_journal_emergence%20of%20knock-down%20resistance%20in%20the%20anopheles.pdf","pdf_url":"https://archive.lstmed.ac.uk/8705/1/malaria_journal_emergence%20of%20knock-down%20resistance%20in%20the%20anopheles.pdf","source":{"id":"https://openalex.org/S4306400185","display_name":"LSTM Online Archive (Liverpool School of Tropical Medicine)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I194839184","host_organization_name":"Liverpool School of Tropical Medicine","host_organization_lineage":["https://openalex.org/I194839184"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:researchonline.lshtm.ac.uk:4647847","doi":null,"is_oa":false,"landing_page_url":"https://researchonline.lshtm.ac.uk/id/eprint/4647847/1/Emergence%20of%20knock-down%20resistance%20in%20the%20Anopheles%20gambiae%20complex%20in%20the%20Upper%20River%20Region_GOLD%20VoR.pdf","pdf_url":"https://researchonline.lshtm.ac.uk/id/eprint/4647847/1/Emergence%20of%20knock-down%20resistance%20in%20the%20Anopheles%20gambiae%20complex%20in%20the%20Upper%20River%20Region_GOLD%20VoR.pdf","source":{"id":"https://openalex.org/S4306402527","display_name":"LSHTM Research Online (London School of Hygiene and Tropical Medicine)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210089966","host_organization_name":"London School of Hygiene & Tropical Medicine","host_organization_lineage":["https://openalex.org/I4210089966"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:dro.dur.ac.uk.OAI2:24925","doi":null,"is_oa":true,"landing_page_url":"http://dro.dur.ac.uk/24925/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400188","display_name":"Durham Research Online (Durham University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I190082696","host_organization_name":"Durham University","host_organization_lineage":["https://openalex.org/I190082696"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Malaria journal, 2018, Vol.17, pp.205 [Peer Reviewed Journal]","raw_type":"Article"},{"id":"pmh:oai:https://durham-repository.worktribe.com/:1338763","doi":null,"is_oa":true,"landing_page_url":"https://durham-repository.worktribe.com/output/1338763","pdf_url":"https://durham-repository.worktribe.com/file/1338763/1/Published%20Journal%20Article","source":{"id":"https://openalex.org/S4306400188","display_name":"Durham Research Online (Durham University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I190082696","host_organization_name":"Durham University","host_organization_lineage":["https://openalex.org/I190082696"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:38c1075708be481e9f9c83d0238495ec","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/38c1075708be481e9f9c83d0238495ec","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Malaria Journal, Vol 17, Iss 1, Pp 1-14 (2018)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12936-018-2348-8","doi":"https://doi.org/10.1186/s12936-018-2348-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12936-018-2348-8","pdf_url":"https://malariajournal.biomedcentral.com/track/pdf/10.1186/s12936-018-2348-8","source":{"id":"https://openalex.org/S93003929","display_name":"Malaria Journal","issn_l":"1475-2875","issn":["1475-2875"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Malaria Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G303718351","display_name":null,"funder_award_id":"GO900220","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G7888718989","display_name":null,"funder_award_id":"MR/K012126/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2803727503.pdf","grobid_xml":"https://content.openalex.org/works/W2803727503.grobid-xml"},"referenced_works_count":56,"referenced_works":["https://openalex.org/W65569829","https://openalex.org/W108789131","https://openalex.org/W186670105","https://openalex.org/W1576491527","https://openalex.org/W1729017034","https://openalex.org/W1755904813","https://openalex.org/W1831100553","https://openalex.org/W1911482274","https://openalex.org/W1957543647","https://openalex.org/W1966305938","https://openalex.org/W1973110432","https://openalex.org/W1973843193","https://openalex.org/W1984322287","https://openalex.org/W1992504336","https://openalex.org/W1994108690","https://openalex.org/W2004277758","https://openalex.org/W2007985281","https://openalex.org/W2010156490","https://openalex.org/W2015937705","https://openalex.org/W2020845459","https://openalex.org/W2050310080","https://openalex.org/W2051157460","https://openalex.org/W2064422391","https://openalex.org/W2077506387","https://openalex.org/W2079981827","https://openalex.org/W2095740662","https://openalex.org/W2096309440","https://openalex.org/W2098576362","https://openalex.org/W2105748597","https://openalex.org/W2106675599","https://openalex.org/W2109437864","https://openalex.org/W2111211900","https://openalex.org/W2111572642","https://openalex.org/W2115907339","https://openalex.org/W2119684348","https://openalex.org/W2121626072","https://openalex.org/W2123760223","https://openalex.org/W2124056533","https://openalex.org/W2127249471","https://openalex.org/W2128489222","https://openalex.org/W2132833880","https://openalex.org/W2134894129","https://openalex.org/W2136780927","https://openalex.org/W2139733800","https://openalex.org/W2142763096","https://openalex.org/W2147851766","https://openalex.org/W2156360666","https://openalex.org/W2164748390","https://openalex.org/W2166231658","https://openalex.org/W2167898992","https://openalex.org/W2280220883","https://openalex.org/W2289131707","https://openalex.org/W2297262208","https://openalex.org/W2404054894","https://openalex.org/W2407763776","https://openalex.org/W2803727503"],"related_works":["https://openalex.org/W3214926804","https://openalex.org/W2399424413","https://openalex.org/W7164339525","https://openalex.org/W2143946522","https://openalex.org/W3200761299","https://openalex.org/W4389923015","https://openalex.org/W2049954484","https://openalex.org/W3216386582","https://openalex.org/W1971316888","https://openalex.org/W2900393200"],"abstract_inverted_index":{"BACKGROUND:":[0],"Insecticide":[1],"resistance":[2,10,51,246],"threatens":[3],"malaria":[4,60,96,197,255],"control":[5],"in":[6,15,26,52,62,64,75,98,145,153,166,181,188,206],"sub-Saharan":[7],"Africa.":[8],"Knockdown":[9],"to":[11,45,94,132,148,161,242],"pyrethroids":[12],"and":[13,56,109,150,178,210,234],"organochlorines":[14],"Anopheles":[16,107,110],"gambiae":[17,54,77,119,171,186,208,236],"sensu":[18,120],"lato":[19],"(s.l.)":[20],"is":[21,35],"commonly":[22],"caused":[23],"by":[24],"mutations":[25,68,177,201,233],"the":[27,36,40,70,88,91,115,126,135,154,167,182,215,219,251],"gene":[28],"encoding":[29],"a":[30,80,189,226],"voltage-gated":[31],"sodium":[32],"channel":[33],"which":[34],"target":[37],"site":[38],"for":[39,49,125],"insecticide.":[41],"The":[42,137],"study":[43,216],"aimed":[44],"examine":[46],"risk":[47,252],"factors":[48],"knockdown":[50],"An.":[53,76,118,170,185,207,235],"s.l.":[55,78,172],"its":[57],"relationship":[58],"with":[59,156,174,194],"infection":[61,97],"children":[63,99],"rural":[65],"Gambia.":[66],"Point":[67],"at":[69,87],"Vgsc-1014":[71,113],"locus,":[72],"were":[73,85,191,222],"measured":[74],"during":[79,134,214],"2-year":[81],"trial.":[82],"Cross-sectional":[83],"surveys":[84],"conducted":[86],"end":[89],"of":[90,117,169,184,228,253],"transmission":[92],"season":[93],"measure":[95],"aged":[100],"6":[101],"months-14":[102],"years.":[103],"RESULTS:":[104],"Whilst":[105],"few":[106],"arabiensis":[108],"coluzzii":[111],"had":[112],"mutations,":[114],"proportion":[116,168,183],"stricto":[121],"(s.s.)":[122],"mosquitoes":[123,173],"homozygous":[124,175,231],"Vgsc-1014F":[127,176,200,232],"mutation":[128,141],"increased":[129,195,250],"from":[130],"64.8":[131],"90.9%":[133],"study.":[136],"Vgsc-1014S":[138],"or":[139,247],"1014F":[140],"was":[142,239],"80%":[143],"higher":[144,152],"2011":[146],"compared":[147,160],"2010,":[149],"27%":[151],"villages":[155],"indoor":[157],"residual":[158],"spraying":[159],"those":[162],"without.":[163],"An":[164],"increase":[165,180],"an":[179],"s.s.":[187,209],"cluster":[190],"each":[192],"associated":[193],"childhood":[196,254],"infection.":[198,256],"Homozygous":[199],"were,":[202],"however,":[203],"most":[204],"common":[205],"almost":[211],"reached":[212],"saturation":[213],"meaning":[217],"that":[218],"two":[220],"variables":[221],"colinear.":[223],"CONCLUSIONS:":[224],"As":[225],"result":[227],"colinearity":[229],"between":[230],"s.s.,":[237],"it":[238],"not":[240],"possible":[241],"determine":[243],"whether":[244],"insecticide":[245],"species":[248],"composition":[249]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-06-01T00:00:00"}
