{"id":"https://openalex.org/W2803554466","doi":"https://doi.org/10.1021/acs.nanolett.8b00572","title":"Detection of Sub-fM DNA with Target Recycling and Self-Assembly Amplification on Graphene Field-Effect Biosensors","display_name":"Detection of Sub-fM DNA with Target Recycling and Self-Assembly Amplification on Graphene Field-Effect Biosensors","publication_year":2018,"publication_date":"2018-05-16","ids":{"openalex":"https://openalex.org/W2803554466","doi":"https://doi.org/10.1021/acs.nanolett.8b00572","mag":"2803554466","pmid":"https://pubmed.ncbi.nlm.nih.gov/29768011","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6002779"},"language":"en","primary_location":{"id":"doi:10.1021/acs.nanolett.8b00572","doi":"https://doi.org/10.1021/acs.nanolett.8b00572","is_oa":true,"landing_page_url":"https://doi.org/10.1021/acs.nanolett.8b00572","pdf_url":null,"source":{"id":"https://openalex.org/S143846845","display_name":"Nano Letters","issn_l":"1530-6984","issn":["1530-6984","1530-6992"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nano Letters","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1021/acs.nanolett.8b00572","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041974481","display_name":"Zhaoli Gao","orcid":"https://orcid.org/0000-0003-3114-2207","observed_orcids":["https://orcid.org/0000-0003-3114-2207"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhaoli Gao","raw_affiliation_strings":["University of Pennsylvania , , , ,","Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pennsylvania , , , ,","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Han Xia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]},{"id":"https://openalex.org/I4210131174","display_name":"Southwest Hospital","ror":"https://ror.org/02jn36537","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210131174"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Han Xia","raw_affiliation_strings":["Third Military Medical University (Army Medical University) , , ,","University of Pennsylvania , , , ,","Department of Laboratory Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, P. R. China","Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Third Military Medical University (Army Medical University) , , ,","institution_ids":["https://openalex.org/I151075929"]},{"raw_affiliation_string":"University of Pennsylvania , , , ,","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Department of Laboratory Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, P. R. China","institution_ids":["https://openalex.org/I151075929","https://openalex.org/I4210131174"]},{"raw_affiliation_string":"Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048875581","display_name":"Jonathan Zauberman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan Zauberman","raw_affiliation_strings":["University of Pennsylvania , , , ,","Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pennsylvania , , , ,","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055181182","display_name":"Maurizio Tomaiuolo","orcid":"https://orcid.org/0000-0002-1453-1297","observed_orcids":["https://orcid.org/0000-0002-1453-1297","https://orcid.org/0009-0007-1365-8150"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maurizio Tomaiuolo","raw_affiliation_strings":["University of Pennsylvania , , , ,","Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pennsylvania , , , ,","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061159056","display_name":"Jinglei Ping","orcid":"https://orcid.org/0000-0003-0386-8828","observed_orcids":["https://orcid.org/0000-0003-0386-8828"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jinglei Ping","raw_affiliation_strings":["University of Pennsylvania , , , ,","Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pennsylvania , , , ,","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100652206","display_name":"Qicheng Zhang","orcid":"https://orcid.org/0000-0003-0773-9732","observed_orcids":["https://orcid.org/0000-0003-0773-9732","https://orcid.org/0000-0002-3414-4083"]},"institutions":[{"id":"https://openalex.org/I200769079","display_name":"Hong Kong University of Science and Technology","ror":"https://ror.org/00q4vv597","country_code":"HK","type":"education","lineage":["https://openalex.org/I200769079"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["HK","US"],"is_corresponding":false,"raw_author_name":"Qicheng Zhang","raw_affiliation_strings":["Hong Kong University of Science and Technology , , Clear Water Bay, ,","University of Pennsylvania , , , ,","Department of Chemical and Biomolecular Engineering, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong","Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States"],"raw_orcid":"https://orcid.org/0000-0002-3414-4083","affiliations":[{"raw_affiliation_string":"Hong Kong University of Science and Technology , , Clear Water Bay, ,","institution_ids":["https://openalex.org/I200769079"]},{"raw_affiliation_string":"University of Pennsylvania , , , ,","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Department of Chemical and Biomolecular Engineering, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong","institution_ids":["https://openalex.org/I200769079"]},{"raw_affiliation_string":"Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040988700","display_name":"Pedro Ducos","orcid":"https://orcid.org/0000-0002-4273-8340","observed_orcids":["https://orcid.org/0000-0002-4273-8340"]},"institutions":[{"id":"https://openalex.org/I69094615","display_name":"Universidad San Francisco de Quito","ror":"https://ror.org/01r2c3v86","country_code":"EC","type":"education","lineage":["https://openalex.org/I69094615"]}],"countries":["EC"],"is_corresponding":false,"raw_author_name":"Pedro Ducos","raw_affiliation_strings":["Universidad San Francisco de Quito , , ,","Departamento de F\u00edsica, Universidad San Francisco de Quito, Quito 170901, Ecuador"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidad San Francisco de Quito , , ,","institution_ids":["https://openalex.org/I69094615"]},{"raw_affiliation_string":"Departamento de F\u00edsica, Universidad San Francisco de Quito, Quito 170901, Ecuador","institution_ids":["https://openalex.org/I69094615"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061840473","display_name":"Huacheng Ye","orcid":"https://orcid.org/0000-0003-3800-1335","observed_orcids":["https://orcid.org/0000-0003-3800-1335"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Huacheng Ye","raw_affiliation_strings":["University of Pennsylvania , , , ,","Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pennsylvania , , , ,","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100371239","display_name":"Sheng Wang","orcid":"https://orcid.org/0000-0001-7923-478X","observed_orcids":["https://orcid.org/0000-0001-7923-478X","https://orcid.org/0000-0002-6523-716X"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sheng Wang","raw_affiliation_strings":["University of Pennsylvania , , , ,","Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pennsylvania , , , ,","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039402755","display_name":"Xinping Yang","orcid":"https://orcid.org/0000-0003-4086-4180","observed_orcids":["https://orcid.org/0000-0003-4086-4180"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xinping Yang","raw_affiliation_strings":["University of Pennsylvania , , , ,","Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pennsylvania , , , ,","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015302454","display_name":"Fahmida Lubna","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fahmida Lubna","raw_affiliation_strings":["University of Pennsylvania , , , ,","Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pennsylvania , , , ,","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014126199","display_name":"Zhengtang Luo","orcid":"https://orcid.org/0000-0002-5134-9240","observed_orcids":["https://orcid.org/0000-0002-5134-9240","https://orcid.org/0000-0002-4822-9694","https://orcid.org/0000-0001-7101-2867"]},"institutions":[{"id":"https://openalex.org/I200769079","display_name":"Hong Kong University of Science and Technology","ror":"https://ror.org/00q4vv597","country_code":"HK","type":"education","lineage":["https://openalex.org/I200769079"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Zhengtang Luo","raw_affiliation_strings":["Hong Kong University of Science and Technology , , Clear Water Bay, ,","Department of Chemical and Biomolecular Engineering, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong"],"raw_orcid":"https://orcid.org/0000-0002-4822-9694","affiliations":[{"raw_affiliation_string":"Hong Kong University of Science and Technology , , Clear Water Bay, ,","institution_ids":["https://openalex.org/I200769079"]},{"raw_affiliation_string":"Department of Chemical and Biomolecular Engineering, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong","institution_ids":["https://openalex.org/I200769079"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100674571","display_name":"Li Ren","orcid":"https://orcid.org/0000-0003-0604-9166","observed_orcids":["https://orcid.org/0000-0003-0604-9166","https://orcid.org/0000-0001-8841-8505","https://orcid.org/0009-0000-3956-7125","https://orcid.org/0009-0006-5848-7204"]},"institutions":[{"id":"https://openalex.org/I90610280","display_name":"South China University of Technology","ror":"https://ror.org/0530pts50","country_code":"CN","type":"education","lineage":["https://openalex.org/I90610280"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Li Ren","raw_affiliation_strings":["South China University of Technology , , ,","School of Materials Science and Engineering, South China University of Technology, Guangzhou 510006, P. R. China"],"raw_orcid":"https://orcid.org/0000-0003-0604-9166","affiliations":[{"raw_affiliation_string":"South China University of Technology , , ,","institution_ids":["https://openalex.org/I90610280"]},{"raw_affiliation_string":"School of Materials Science and Engineering, South China University of Technology, Guangzhou 510006, P. R. China","institution_ids":["https://openalex.org/I90610280"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022465363","display_name":"Alan T. Charlie Johnson","orcid":"https://orcid.org/0000-0002-5402-1224","observed_orcids":["https://orcid.org/0000-0002-5402-1224"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Alan T. Charlie Johnson","raw_affiliation_strings":["University of Pennsylvania , , , ,","Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States"],"raw_orcid":"https://orcid.org/0000-0002-5402-1224","affiliations":[{"raw_affiliation_string":"University of Pennsylvania , , , ,","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States","institution_ids":["https://openalex.org/I79576946"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5022465363","https://openalex.org/A5100674571"],"corresponding_institution_ids":["https://openalex.org/I79576946","https://openalex.org/I90610280"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":{"value":2559,"currency":"EUR","value_usd":2759},"fwci":3.8243,"has_fulltext":true,"cited_by_count":108,"citation_normalized_percentile":{"value":0.95304677,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"18","issue":"6","first_page":"3509","last_page":"3515"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.010900000110268593,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/graphene-field-effect-transistors","display_name":"graphene field-effect transistors","score":0.9610000252723694},{"id":"https://openalex.org/keywords/dna-biosensor","display_name":"DNA biosensor","score":0.9480000138282776},{"id":"https://openalex.org/keywords/target-recycling","display_name":"target recycling","score":0.6240000128746033},{"id":"https://openalex.org/keywords/hybridization-chain-reaction","display_name":"hybridization chain reaction","score":0.8930000066757202},{"id":"https://openalex.org/keywords/single-base-mismatch-discrimination","display_name":"single-base mismatch discrimination","score":0.675000011920929}],"concepts":[{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.9053895473480225},{"id":"https://openalex.org/C129312508","wikidata":"https://www.wikidata.org/wiki/Q133686","display_name":"Oligonucleotide","level":3,"score":0.6422589421272278},{"id":"https://openalex.org/C24107716","wikidata":"https://www.wikidata.org/wiki/Q123619","display_name":"Nucleic acid","level":2,"score":0.6178736686706543},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5459749102592468},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.5402076244354248},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.493745893239975},{"id":"https://openalex.org/C119203544","wikidata":"https://www.wikidata.org/wiki/Q425891","display_name":"Molecular beacon","level":4,"score":0.45501604676246643},{"id":"https://openalex.org/C19275194","wikidata":"https://www.wikidata.org/wiki/Q222903","display_name":"Multiplexing","level":2,"score":0.4459105134010315},{"id":"https://openalex.org/C21200559","wikidata":"https://www.wikidata.org/wiki/Q7451068","display_name":"Sensitivity (control systems)","level":2,"score":0.4363086521625519},{"id":"https://openalex.org/C30080830","wikidata":"https://www.wikidata.org/wiki/Q169917","display_name":"Graphene","level":2,"score":0.43131938576698303},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.3494633734226227},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.30910784006118774},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.20114398002624512},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.15077179670333862},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09295323491096497},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006108","descriptor_name":"Graphite","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D009693","descriptor_name":"Nucleic Acid Hybridization","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D014173","descriptor_name":"Transistors, Electronic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015342","descriptor_name":"DNA Probes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1021/acs.nanolett.8b00572","doi":"https://doi.org/10.1021/acs.nanolett.8b00572","is_oa":true,"landing_page_url":"https://doi.org/10.1021/acs.nanolett.8b00572","pdf_url":null,"source":{"id":"https://openalex.org/S143846845","display_name":"Nano Letters","issn_l":"1530-6984","issn":["1530-6984","1530-6992"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nano Letters","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6002779","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6002779/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6002779/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nano Lett","raw_type":"Text"},{"id":"pmh:oai:europepmc.org:4959569","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6002779","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:29768011","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29768011","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nano letters","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1021/acs.nanolett.8b00572","doi":"https://doi.org/10.1021/acs.nanolett.8b00572","is_oa":true,"landing_page_url":"https://doi.org/10.1021/acs.nanolett.8b00572","pdf_url":null,"source":{"id":"https://openalex.org/S143846845","display_name":"Nano Letters","issn_l":"1530-6984","issn":["1530-6984","1530-6992"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nano Letters","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1048009158","display_name":null,"funder_award_id":"201704030134","funder_id":"https://openalex.org/F4320334898","funder_display_name":"Guangzhou Science and Technology Program key projects"},{"id":"https://openalex.org/G2061385195","display_name":null,"funder_award_id":"1542879","funder_id":"https://openalex.org/F4320337395","funder_display_name":"Division of Emerging Frontiers in Research and Innovation"},{"id":"https://openalex.org/G2259824668","display_name":null,"funder_award_id":"2017YFC1105000","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G2843848390","display_name":"EFRI 2-DARE: Functionalized Monolayer Heterostructures for Biosensors with Optical Readout","funder_award_id":"1542879","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G4227328392","display_name":null,"funder_award_id":"CNERC14SC01","funder_id":"https://openalex.org/F4320321920","funder_display_name":"Innovation and Technology Commission"},{"id":"https://openalex.org/G4995373955","display_name":"Low Temperature Patterned CVD-Growth of Bandgap-Engineered Graphene Nanostructures","funder_award_id":"16204815","funder_id":"https://openalex.org/F4320321592","funder_display_name":"Research Grants Council, University Grants Committee"},{"id":"https://openalex.org/G534716927","display_name":null,"funder_award_id":"ITC- CNERC-14SC01","funder_id":"https://openalex.org/F4320321920","funder_display_name":"Innovation and Technology Commission"},{"id":"https://openalex.org/G5968825137","display_name":null,"funder_award_id":"2016201604030023","funder_id":"https://openalex.org/F4320334898","funder_display_name":"Guangzhou Science and Technology Program key projects"},{"id":"https://openalex.org/G796739815","display_name":null,"funder_award_id":"2017YFC1105000","funder_id":"https://openalex.org/F4320321540","funder_display_name":"Ministry of Science and Technology of the People's Republic of China"},{"id":"https://openalex.org/G8199396359","display_name":null,"funder_award_id":"ITS/267/15","funder_id":"https://openalex.org/F4320321920","funder_display_name":"Innovation and Technology Commission"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306137","display_name":"Bill and Melinda Gates Foundation","ror":"https://ror.org/0456r8d26"},{"id":"https://openalex.org/F4320309370","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10"},{"id":"https://openalex.org/F4320310419","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231"},{"id":"https://openalex.org/F4320321540","display_name":"Ministry of Science and Technology of the People's Republic of China","ror":"https://ror.org/027s68j25"},{"id":"https://openalex.org/F4320321592","display_name":"Research Grants Council, University Grants Committee","ror":"https://ror.org/00djwmt25"},{"id":"https://openalex.org/F4320321920","display_name":"Innovation and Technology Commission","ror":"https://ror.org/04vf9tr09"},{"id":"https://openalex.org/F4320334898","display_name":"Guangzhou Science and Technology Program key projects","ror":"https://ror.org/00tjzgn92"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null},{"id":"https://openalex.org/F4320337395","display_name":"Division of Emerging Frontiers in Research and Innovation","ror":"https://ror.org/0388pet74"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2803554466.pdf","grobid_xml":"https://content.openalex.org/works/W2803554466.grobid-xml"},"referenced_works_count":32,"referenced_works":["https://openalex.org/W1802069116","https://openalex.org/W1974254202","https://openalex.org/W1974903555","https://openalex.org/W1991472095","https://openalex.org/W1996491588","https://openalex.org/W2002744212","https://openalex.org/W2008662133","https://openalex.org/W2017631291","https://openalex.org/W2036758819","https://openalex.org/W2043177279","https://openalex.org/W2048090945","https://openalex.org/W2049142984","https://openalex.org/W2050574264","https://openalex.org/W2051365563","https://openalex.org/W2066649475","https://openalex.org/W2070024241","https://openalex.org/W2080880982","https://openalex.org/W2109007387","https://openalex.org/W2114048053","https://openalex.org/W2135995702","https://openalex.org/W2148304424","https://openalex.org/W2150963761","https://openalex.org/W2156484017","https://openalex.org/W2200245088","https://openalex.org/W2220110130","https://openalex.org/W2334035222","https://openalex.org/W2514129698","https://openalex.org/W2527184168","https://openalex.org/W2603262868","https://openalex.org/W2951538444","https://openalex.org/W3105782922","https://openalex.org/W4211066815"],"related_works":["https://openalex.org/W2514129698","https://openalex.org/W3133871961","https://openalex.org/W6987004761","https://openalex.org/W4386084181","https://openalex.org/W2527184168","https://openalex.org/W2154374435","https://openalex.org/W3006009743","https://openalex.org/W2026451143","https://openalex.org/W4416644300","https://openalex.org/W3031144472"],"abstract_inverted_index":{"All-electronic":[0],"DNA":[1,60,77],"biosensors":[2,116],"based":[3,20,92],"on":[4,21,93],"graphene":[5],"field-effect":[6],"transistors":[7],"(GFETs)":[8],"offer":[9],"the":[10,25,30,34,38,54,110],"prospect":[11],"of":[12,33,56,73,113],"simple":[13],"and":[14,66,81,117,123,131],"cost-effective":[15],"diagnostics.":[16],"For":[17],"GFET":[18],"sensors":[19],"complementary":[22],"probe":[23,59],"DNA,":[24],"sensitivity":[26,52,112],"is":[27,91,102],"limited":[28],"by":[29],"binding":[31],"affinity":[32],"target":[35,64,76],"oligonucleotide,":[36],"in":[37,51],"nM":[39],"range":[40],"for":[41,63,98,104],"20":[42],"mer":[43,75],"targets.":[44],"We":[45],"report":[46],"a":[47,94,119],"\u223c20":[48],"000\u00d7":[49],"improvement":[50],"through":[53],"use":[55],"engineered":[57],"hairpin":[58],"that":[61,101],"allows":[62],"recycling":[65],"hybridization":[67],"chain":[68],"reaction.":[69],"This":[70,107],"enables":[71],"detection":[72],"21":[74],"at":[78],"sub-fM":[79],"concentration":[80],"provides":[82],"superior":[83],"specificity":[84],"against":[85],"single-base":[86],"mismatched":[87],"oligomers.":[88],"The":[89],"work":[90],"scalable":[95],"fabrication":[96],"process":[97],"biosensor":[99],"arrays":[100],"suitable":[103],"multiplexed":[105,122],"detection.":[106],"approach":[108],"overcomes":[109],"binding-affinity-dependent":[111],"nucleic":[114,125],"acid":[115,126],"offers":[118],"pathway":[120],"toward":[121],"label-free":[124],"testing":[127],"with":[128],"high":[129],"accuracy":[130],"selectivity.":[132]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":15},{"year":2023,"cited_by_count":17},{"year":2022,"cited_by_count":13},{"year":2021,"cited_by_count":16},{"year":2020,"cited_by_count":16},{"year":2019,"cited_by_count":16},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2018-06-01T00:00:00"}