{"id":"https://openalex.org/W2803433102","doi":"https://doi.org/10.1016/j.immuni.2018.04.009","title":"Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis","display_name":"Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis","publication_year":2018,"publication_date":"2018-05-22","ids":{"openalex":"https://openalex.org/W2803433102","doi":"https://doi.org/10.1016/j.immuni.2018.04.009","mag":"2803433102","pmid":"https://pubmed.ncbi.nlm.nih.gov/29802020","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6024031"},"language":"en","primary_location":{"id":"doi:10.1016/j.immuni.2018.04.009","doi":"https://doi.org/10.1016/j.immuni.2018.04.009","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.immuni.2018.04.009","pdf_url":"http://www.cell.com/article/S1074761318301468/pdf","source":{"id":"https://openalex.org/S199671312","display_name":"Immunity","issn_l":"1074-7613","issn":["1074-7613","1097-4180"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunity","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://www.cell.com/article/S1074761318301468/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022366571","display_name":"Keiji Hirota","orcid":"https://orcid.org/0000-0002-4737-0661","observed_orcids":["https://orcid.org/0000-0002-4737-0661"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I4405287342","display_name":"Immunology Frontier Research Center, The University of Osaka","ror":"https://ror.org/04xm7dy51","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4405287342","https://openalex.org/I98285908"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Keiji Hirota","raw_affiliation_strings":["Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan; Laboratory of Integrative Biological Science, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan. Electronic address: hkeiji@infront.kyoto-u.ac.jp","Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan","Laboratory of Integrative Biological Science, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan; Laboratory of Integrative Biological Science, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan. Electronic address: hkeiji@infront.kyoto-u.ac.jp","institution_ids":["https://openalex.org/I22299242","https://openalex.org/I4405287342","https://openalex.org/I98285908"]},{"raw_affiliation_string":"Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan","institution_ids":["https://openalex.org/I4405287342","https://openalex.org/I98285908"]},{"raw_affiliation_string":"Laboratory of Integrative Biological Science, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039685784","display_name":"Motomu Hashimoto","orcid":"https://orcid.org/0000-0002-9241-060X","observed_orcids":["https://orcid.org/0000-0002-9241-060X"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Motomu Hashimoto","raw_affiliation_strings":["Department of Advanced Medicine for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Advanced Medicine for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028272167","display_name":"Yoshinaga Ito","orcid":"https://orcid.org/0000-0002-5567-7014","observed_orcids":["https://orcid.org/0000-0002-5567-7014"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshinaga Ito","raw_affiliation_strings":["Laboratory of Experimental Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Experimental Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Mayumi Matsuura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mayumi Matsuura","raw_affiliation_strings":["Laboratory of Experimental Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Experimental Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074384098","display_name":"Hiromu Ito","orcid":"https://orcid.org/0000-0002-1827-382X","observed_orcids":["https://orcid.org/0000-0002-1827-382X"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiromu Ito","raw_affiliation_strings":["Department of Advanced Medicine for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan; Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan","Department of Advanced Medicine for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan","Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Advanced Medicine for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan; Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"Department of Advanced Medicine for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078409741","display_name":"Masao Tanaka","orcid":"https://orcid.org/0000-0002-8942-2933","observed_orcids":["https://orcid.org/0000-0002-8942-2933"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masao Tanaka","raw_affiliation_strings":["Department of Advanced Medicine for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Advanced Medicine for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101437005","display_name":"Hitomi Watanabe","orcid":"https://orcid.org/0000-0001-6448-9966","observed_orcids":["https://orcid.org/0000-0001-6448-9966"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hitomi Watanabe","raw_affiliation_strings":["Laboratory of Integrative Biological Science, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Integrative Biological Science, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081382521","display_name":"Gen Kondoh","orcid":"https://orcid.org/0000-0002-2564-0149","observed_orcids":["https://orcid.org/0000-0002-2564-0149"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Gen Kondoh","raw_affiliation_strings":["Laboratory of Integrative Biological Science, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Integrative Biological Science, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056185976","display_name":"Atsushi Tanaka","orcid":"https://orcid.org/0000-0003-1660-9892","observed_orcids":["https://orcid.org/0000-0003-1660-9892"]},"institutions":[{"id":"https://openalex.org/I4405287342","display_name":"Immunology Frontier Research Center, The University of Osaka","ror":"https://ror.org/04xm7dy51","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4405287342","https://openalex.org/I98285908"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Atsushi Tanaka","raw_affiliation_strings":["Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan","institution_ids":["https://openalex.org/I4405287342","https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110318885","display_name":"Keiko Yasuda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405287342","display_name":"Immunology Frontier Research Center, The University of Osaka","ror":"https://ror.org/04xm7dy51","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4405287342","https://openalex.org/I98285908"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Keiko Yasuda","raw_affiliation_strings":["Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan","institution_ids":["https://openalex.org/I4405287342","https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087304114","display_name":"Manfred K\u00f6pf","orcid":"https://orcid.org/0000-0002-0628-7140","observed_orcids":["https://orcid.org/0000-0002-0628-7140"]},"institutions":[{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]},{"id":"https://openalex.org/I4405257820","display_name":"Institute of Molecular Health Sciences","ror":"https://ror.org/05q2cwx50","country_code":"CH","type":"facility","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088","https://openalex.org/I4405257820"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Manfred Kopf","raw_affiliation_strings":["Department of Biology, Institute of Molecular Health Sciences, ETH Z\u00fcrich, 8093 Z\u00fcrich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Institute of Molecular Health Sciences, ETH Z\u00fcrich, 8093 Z\u00fcrich, Switzerland","institution_ids":["https://openalex.org/I35440088","https://openalex.org/I4405257820"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033091007","display_name":"Alexandre J. Potocnik","orcid":"https://orcid.org/0000-0002-4730-8593","observed_orcids":["https://orcid.org/0000-0002-4730-8593"]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alexandre J. Potocnik","raw_affiliation_strings":["Institute of Immunology and Infection Research, The University of Edinburgh, Edinburgh EH9 3FL, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Immunology and Infection Research, The University of Edinburgh, Edinburgh EH9 3FL, UK","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059045389","display_name":"Brigitta Stockinger","orcid":"https://orcid.org/0000-0001-8781-336X","observed_orcids":["https://orcid.org/0000-0001-8781-336X"]},"institutions":[{"id":"https://openalex.org/I2801081054","display_name":"The Francis Crick Institute","ror":"https://ror.org/04tnbqb63","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Brigitta Stockinger","raw_affiliation_strings":["AhR Immunity Laboratory, The Francis Crick Institute, London NW1 1AT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AhR Immunity Laboratory, The Francis Crick Institute, London NW1 1AT, UK","institution_ids":["https://openalex.org/I2801081054"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013291986","display_name":"Noriko Sakaguchi","orcid":"https://orcid.org/0000-0003-2632-7688","observed_orcids":["https://orcid.org/0000-0003-2632-7688"]},"institutions":[{"id":"https://openalex.org/I4405287342","display_name":"Immunology Frontier Research Center, The University of Osaka","ror":"https://ror.org/04xm7dy51","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4405287342","https://openalex.org/I98285908"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Noriko Sakaguchi","raw_affiliation_strings":["Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan","institution_ids":["https://openalex.org/I4405287342","https://openalex.org/I98285908"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025764166","display_name":"Shimon Sakaguchi","orcid":"https://orcid.org/0000-0001-8265-6094","observed_orcids":["https://orcid.org/0000-0001-8265-6094"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I4405287342","display_name":"Immunology Frontier Research Center, The University of Osaka","ror":"https://ror.org/04xm7dy51","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4405287342","https://openalex.org/I98285908"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Shimon Sakaguchi","raw_affiliation_strings":["Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan; Laboratory of Experimental Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan. Electronic address: shimon@ifrec.osaka-u.ac.jp","Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan","Laboratory of Experimental Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan; Laboratory of Experimental Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan. Electronic address: shimon@ifrec.osaka-u.ac.jp","institution_ids":["https://openalex.org/I22299242","https://openalex.org/I4405287342","https://openalex.org/I98285908"]},{"raw_affiliation_string":"Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan","institution_ids":["https://openalex.org/I4405287342","https://openalex.org/I98285908"]},{"raw_affiliation_string":"Laboratory of Experimental Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan","institution_ids":["https://openalex.org/I22299242"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5022366571","https://openalex.org/A5025764166"],"corresponding_institution_ids":["https://openalex.org/I22299242","https://openalex.org/I4405287342","https://openalex.org/I98285908"],"apc_list":{"value":10400,"currency":"USD","value_usd":10400},"apc_paid":{"value":10400,"currency":"USD","value_usd":10400},"fwci":18.4328,"has_fulltext":true,"cited_by_count":183,"citation_normalized_percentile":{"value":0.99705479,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"48","issue":"6","first_page":"1220","last_page":"1232.e5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.5776000022888184,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.5776000022888184,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12528","display_name":"IL-33, ST2, and ILC Pathways","score":0.28299999237060547,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis","score":0.09030000120401382,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/th17-cells","display_name":"Th17 cells","score":0.9919999837875366},{"id":"https://openalex.org/keywords/autoimmune-arthritis","display_name":"autoimmune arthritis","score":0.7379999756813049},{"id":"https://openalex.org/keywords/gm-csf","display_name":"GM-CSF","score":0.7620000243186951},{"id":"https://openalex.org/keywords/innate-lymphoid-cells","display_name":"innate lymphoid cells","score":0.8550000190734863},{"id":"https://openalex.org/keywords/synovial-stromal-cells","display_name":"synovial stromal cells","score":0.8600000143051147},{"id":"https://openalex.org/keywords/synovial-fibroblasts","display_name":"synovial fibroblasts","score":0.9890000224113464},{"id":"https://openalex.org/keywords/il-17","display_name":"IL-17","score":0.8889999985694885},{"id":"https://openalex.org/keywords/il-33","display_name":"IL-33","score":0.8619999885559082},{"id":"https://openalex.org/keywords/tlr9","display_name":"TLR9","score":0.8560000061988831},{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"rheumatoid arthritis","score":0.9120000004768372},{"id":"https://openalex.org/keywords/chronic-joint-inflammation","display_name":"chronic joint inflammation","score":0.8230000138282776},{"id":"https://openalex.org/keywords/cytokine-production","display_name":"cytokine production","score":0.5220000147819519}],"concepts":[{"id":"https://openalex.org/C47742525","wikidata":"https://www.wikidata.org/wiki/Q13418826","display_name":"Innate lymphoid cell","level":4,"score":0.7106308341026306},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6718915700912476},{"id":"https://openalex.org/C16930146","wikidata":"https://www.wikidata.org/wiki/Q4381253","display_name":"Stromal cell","level":2,"score":0.5342079401016235},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.5037235617637634},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.4882798194885254},{"id":"https://openalex.org/C2777077863","wikidata":"https://www.wikidata.org/wiki/Q170990","display_name":"Arthritis","level":2,"score":0.4770497679710388},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4629000425338745},{"id":"https://openalex.org/C79484868","wikidata":"https://www.wikidata.org/wiki/Q5971673","display_name":"IL-2 receptor","level":4,"score":0.4360206723213196},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3474067449569702},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.3261280655860901},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.298786997795105},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.18179893493652344},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.16288328170776367}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001327","descriptor_name":"Autoimmune Diseases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001327","descriptor_name":"Autoimmune Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013583","descriptor_name":"Synovial Membrane","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013583","descriptor_name":"Synovial Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016178","descriptor_name":"Granulocyte-Macrophage Colony-Stimulating Factor","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D016178","descriptor_name":"Granulocyte-Macrophage Colony-Stimulating Factor","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D017154","descriptor_name":"Stromal Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D017154","descriptor_name":"Stromal Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058504","descriptor_name":"Th17 Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D058504","descriptor_name":"Th17 Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":10,"locations":[{"id":"doi:10.1016/j.immuni.2018.04.009","doi":"https://doi.org/10.1016/j.immuni.2018.04.009","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.immuni.2018.04.009","pdf_url":"http://www.cell.com/article/S1074761318301468/pdf","source":{"id":"https://openalex.org/S199671312","display_name":"Immunity","issn_l":"1074-7613","issn":["1074-7613","1097-4180"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunity","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4982472","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6024031","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6024031","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6024031","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunity","raw_type":"Text"},{"id":"pmid:29802020","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29802020","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunity","raw_type":"Journal Article"},{"id":"pmh:oai:www.research-collection.ethz.ch:20.500.11850/271845","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/20.500.11850/271845","pdf_url":null,"source":{"id":"https://openalex.org/S4306402302","display_name":"Repository for Publications and Research Data (ETH Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I35440088","host_organization_name":"ETH Zurich","host_organization_lineage":["https://openalex.org/I35440088"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunity, 48 (6)","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.ed.ac.uk:openaire/267693f5-04e3-449d-9ce8-c9f15f9f7fc0","doi":null,"is_oa":true,"landing_page_url":"https://www.research.ed.ac.uk/files/103707652/1_s2.0_S1074761318301468_main.pdf","pdf_url":"https://www.research.ed.ac.uk/files/103707652/1_s2.0_S1074761318301468_main.pdf","source":{"id":"https://openalex.org/S4306400321","display_name":"Edinburgh Research Explorer (University of Edinburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I98677209","host_organization_name":"University of Edinburgh","host_organization_lineage":["https://openalex.org/I98677209"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Hirota, K, Hashimoto, M, Ito, Y, Matsuura, M, Ito, H, Tanaka, M, Watanabe, H, Kondoh, G, Tanaka, A, Yasuda, K, Kopf, M, Potocnik, A J, Stockinger, B, Sakaguchi, N & Sakaguchi, S 2018, 'Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis', Immunity, vol. 48, no. 6, pp. 1220-1232.e5. https://doi.org/10.1016/j.immuni.2018.04.009","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:figshare.com:article/12770705","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Autoimmune_Th17_cells_induced_synovial_stromal_and_innate_lymphoid_cell_secretion_of_the_cytokine_GM-CSF_to_initiate_and_augment_autoimmune_arthritis/12770705","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:irdb.nii.ac.jp:01221:0006993930","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2433/297508","pdf_url":null,"source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Immunity","raw_type":"journal article"},{"id":"pmh:oai:repository.kulib.kyoto-u.ac.jp:2433/297508","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2433/297508","pdf_url":null,"source":{"id":"https://openalex.org/S4306401454","display_name":"Kyoto University Research Information Repository (Kyoto University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I22299242","host_organization_name":"Kyoto University","host_organization_lineage":["https://openalex.org/I22299242"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"},{"id":"doi:10.3929/ethz-b-000271845","doi":"https://doi.org/10.3929/ethz-b-000271845","is_oa":true,"landing_page_url":"https://doi.org/10.3929/ethz-b-000271845","pdf_url":null,"source":{"id":"https://openalex.org/S7407051236","display_name":"ETH Z\u00fcrich Research Collection","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1016/j.immuni.2018.04.009","doi":"https://doi.org/10.1016/j.immuni.2018.04.009","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.immuni.2018.04.009","pdf_url":"http://www.cell.com/article/S1074761318301468/pdf","source":{"id":"https://openalex.org/S199671312","display_name":"Immunity","issn_l":"1074-7613","issn":["1074-7613","1097-4180"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunity","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1191630412","display_name":null,"funder_award_id":"FC001159","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G1871263247","display_name":null,"funder_award_id":"16H06233","funder_id":"https://openalex.org/F4320320912","funder_display_name":"Ministry of Education, Culture, Sports, Science and Technology"},{"id":"https://openalex.org/G2521286739","display_name":null,"funder_award_id":"CREST","funder_id":"https://openalex.org/F4320334789","funder_display_name":"Japan Science and Technology Agency"},{"id":"https://openalex.org/G2635969494","display_name":null,"funder_award_id":"FC001159","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G3017254386","display_name":"Study of the function and development of regulatory T cells","funder_award_id":"16H06295","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G3079450316","display_name":null,"funder_award_id":"FC001159","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G4170710306","display_name":"Molecular basis of Treg-specific TCR signaling regulation","funder_award_id":"17K15723","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G6680778435","display_name":"A molecular basis of inflammatory Th17 cells in autoimmune diseases","funder_award_id":"16H06233","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G7469679245","display_name":null,"funder_award_id":"17K19553","funder_id":"https://openalex.org/F4320320912","funder_display_name":"Ministry of Education, Culture, Sports, Science and Technology"},{"id":"https://openalex.org/G7720327255","display_name":null,"funder_award_id":"10159","funder_id":"https://openalex.org/F4320312060","funder_display_name":"Francis Crick Institute"},{"id":"https://openalex.org/G7791091313","display_name":null,"funder_award_id":"FC001159","funder_id":"https://openalex.org/F4320312060","funder_display_name":"Francis Crick Institute"},{"id":"https://openalex.org/G7879866177","display_name":null,"funder_award_id":"CREST","funder_id":"https://openalex.org/F4320320912","funder_display_name":"Ministry of Education, Culture, Sports, Science and Technology"},{"id":"https://openalex.org/G8020082025","display_name":"Elucidation of immunological memory of inflammatory T helper cells","funder_award_id":"17K19553","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G8668949081","display_name":null,"funder_award_id":"16H06295","funder_id":"https://openalex.org/F4320320912","funder_display_name":"Ministry of Education, Culture, Sports, Science and Technology"}],"funders":[{"id":"https://openalex.org/F4320309807","display_name":"Takeda Science Foundation","ror":"https://ror.org/02y123g31"},{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320312060","display_name":"Francis Crick Institute","ror":"https://ror.org/04tnbqb63"},{"id":"https://openalex.org/F4320319985","display_name":"Cancer Research UK","ror":"https://ror.org/054225q67"},{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"},{"id":"https://openalex.org/F4320334789","display_name":"Japan Science and Technology Agency","ror":"https://ror.org/00097mb19"},{"id":"https://openalex.org/F4320338075","display_name":"Core Research for Evolutional Science and Technology","ror":"https://ror.org/00097mb19"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2803433102.pdf","grobid_xml":"https://content.openalex.org/works/W2803433102.grobid-xml"},"referenced_works_count":52,"referenced_works":["https://openalex.org/W332738364","https://openalex.org/W1582010536","https://openalex.org/W1585125753","https://openalex.org/W1595949461","https://openalex.org/W1608909099","https://openalex.org/W1838649406","https://openalex.org/W1870510950","https://openalex.org/W1943296744","https://openalex.org/W1976026025","https://openalex.org/W1989019305","https://openalex.org/W1991070647","https://openalex.org/W1993339415","https://openalex.org/W1995070836","https://openalex.org/W1997745506","https://openalex.org/W1998895238","https://openalex.org/W2000468514","https://openalex.org/W2007435978","https://openalex.org/W2008926589","https://openalex.org/W2008996473","https://openalex.org/W2014782531","https://openalex.org/W2017893786","https://openalex.org/W2033289727","https://openalex.org/W2046957298","https://openalex.org/W2047882259","https://openalex.org/W2065136791","https://openalex.org/W2067401763","https://openalex.org/W2080236371","https://openalex.org/W2084388036","https://openalex.org/W2089685608","https://openalex.org/W2099730228","https://openalex.org/W2101180663","https://openalex.org/W2107951685","https://openalex.org/W2112866067","https://openalex.org/W2117340681","https://openalex.org/W2121833986","https://openalex.org/W2134219545","https://openalex.org/W2140206763","https://openalex.org/W2142017607","https://openalex.org/W2143988830","https://openalex.org/W2146494489","https://openalex.org/W2147975139","https://openalex.org/W2152877078","https://openalex.org/W2155615155","https://openalex.org/W2156316990","https://openalex.org/W2157837362","https://openalex.org/W2158854771","https://openalex.org/W2163478426","https://openalex.org/W2163907633","https://openalex.org/W2164701887","https://openalex.org/W2169663073","https://openalex.org/W2170040424","https://openalex.org/W2471110308"],"related_works":["https://openalex.org/W2808478402","https://openalex.org/W2964707918","https://openalex.org/W2044575809","https://openalex.org/W4235685751","https://openalex.org/W2138404648","https://openalex.org/W1976177645","https://openalex.org/W77344729","https://openalex.org/W4240768428","https://openalex.org/W2324066654","https://openalex.org/W2153953282"],"abstract_inverted_index":{"Despite":[0],"the":[1,43,104],"importance":[2],"of":[3,25,78,106,118,126],"Th17":[4,33,89,95,128],"cells":[5,17,34,52,87,96],"in":[6,18,54,115],"autoimmune":[7,19,27,127],"diseases,":[8],"it":[9],"remains":[10],"unclear":[11],"how":[12],"they":[13],"control":[14],"other":[15],"inflammatory":[16],"tissue":[20],"damage.":[21],"Using":[22],"a":[23,123,145],"model":[24],"spontaneous":[26],"arthritis,":[28],"we":[29],"showed":[30,109],"that":[31,110],"arthritogenic":[32],"stimulated":[35],"fibroblast-like":[36],"synoviocytes":[37],"via":[38,134],"interleukin-17":[39],"(IL-17)":[40],"to":[41],"secrete":[42],"cytokine":[44],"GM-CSF":[45,68,79,92],"and":[46,64,131,136,142],"also":[47],"expanded":[48],"synovial-resident":[49],"innate":[50],"lymphoid":[51],"(ILCs)":[53],"inflamed":[55,116],"joints.":[56],"Activated":[57],"synovial":[58],"ILCs,":[59,130],"which":[60],"expressed":[61],"CD25,":[62],"IL-33Ra,":[63],"TLR9,":[65],"produced":[66],"abundant":[67],"upon":[69],"stimulation":[70],"by":[71,81,94],"IL-2,":[72],"IL-33,":[73],"or":[74,84],"CpG":[75],"DNA.":[76],"Loss":[77],"production":[80,93],"either":[82],"ILCs":[83,112],"radio-resistant":[85],"stromal":[86,132],"prevented":[88],"cell-mediated":[90],"arthritis.":[91,107],"augmented":[97],"chronic":[98,139],"inflammation":[99,141],"but":[100],"was":[101],"dispensable":[102],"for":[103,147],"initiation":[105],"We":[108],"GM-CSF-producing":[111],"were":[113],"present":[114],"joints":[117],"rheumatoid":[119],"arthritis":[120],"patients.":[121],"Thus,":[122],"cellular":[124],"cascade":[125],"cells,":[129,133],"IL-17":[135],"GM-CSF,":[137],"mediates":[138],"joint":[140],"can":[143],"be":[144],"target":[146],"therapeutic":[148],"intervention.":[149]},"counts_by_year":[{"year":2026,"cited_by_count":15},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":15},{"year":2023,"cited_by_count":16},{"year":2022,"cited_by_count":23},{"year":2021,"cited_by_count":32},{"year":2020,"cited_by_count":32},{"year":2019,"cited_by_count":26},{"year":2018,"cited_by_count":9}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2018-06-01T00:00:00"}