{"id":"https://openalex.org/W2803294422","doi":"https://doi.org/10.1085/jgp.201711944","title":"The high-affinity calcium sensor synaptotagmin-7 serves multiple roles in regulated exocytosis","display_name":"The high-affinity calcium sensor synaptotagmin-7 serves multiple roles in regulated exocytosis","publication_year":2018,"publication_date":"2018-05-24","ids":{"openalex":"https://openalex.org/W2803294422","doi":"https://doi.org/10.1085/jgp.201711944","mag":"2803294422","pmid":"https://pubmed.ncbi.nlm.nih.gov/29794152","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5987875"},"language":"en","primary_location":{"id":"doi:10.1085/jgp.201711944","doi":"https://doi.org/10.1085/jgp.201711944","is_oa":true,"landing_page_url":"https://doi.org/10.1085/jgp.201711944","pdf_url":"https://rupress.org/jgp/article-pdf/150/6/783/1234878/jgp_201711944.pdf","source":{"id":"https://openalex.org/S168548653","display_name":"The Journal of General Physiology","issn_l":"0022-1295","issn":["0022-1295","1540-7748"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of General Physiology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://rupress.org/jgp/article-pdf/150/6/783/1234878/jgp_201711944.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038407464","display_name":"Daniel MacDougall","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel D. MacDougall","raw_affiliation_strings":["Department of Pharmacology, University of Michigan, Ann Arbor, MI 1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Michigan, Ann Arbor, MI 1","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070784484","display_name":"Zesen Lin","orcid":"https://orcid.org/0000-0002-1779-1967","observed_orcids":["https://orcid.org/0000-0002-1779-1967"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zesen Lin","raw_affiliation_strings":["Department of Pharmacology, University of Michigan, Ann Arbor, MI 1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Michigan, Ann Arbor, MI 1","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029389474","display_name":"Nara L. Chon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nara L. Chon","raw_affiliation_strings":["Department of Chemistry, University of Colorado, Denver, CO 2"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Colorado, Denver, CO 2","institution_ids":["https://openalex.org/I921990950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053376812","display_name":"Skyler L. Jackman","orcid":"https://orcid.org/0000-0002-6500-3937","observed_orcids":["https://orcid.org/0000-0002-6500-3937"]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]},{"id":"https://openalex.org/I2802707198","display_name":"Vollum Institute","ror":"https://ror.org/054hm6j14","country_code":"US","type":"facility","lineage":["https://openalex.org/I2802707198"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Skyler L. Jackman","raw_affiliation_strings":["Vollum Institute, Oregon Health & Science University, Portland, OR 3"],"raw_orcid":"https://orcid.org/0000-0002-6500-3937","affiliations":[{"raw_affiliation_string":"Vollum Institute, Oregon Health & Science University, Portland, OR 3","institution_ids":["https://openalex.org/I165690674","https://openalex.org/I2802707198"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065919537","display_name":"Hai Lin","orcid":"https://orcid.org/0000-0002-3525-9122","observed_orcids":["https://orcid.org/0000-0002-3525-9122"]},"institutions":[{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hai Lin","raw_affiliation_strings":["Department of Chemistry, University of Colorado, Denver, CO 2"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Colorado, Denver, CO 2","institution_ids":["https://openalex.org/I921990950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046226962","display_name":"Jefferson D. Knight","orcid":"https://orcid.org/0000-0003-2208-4420","observed_orcids":["https://orcid.org/0000-0003-2208-4420"]},"institutions":[{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jefferson D. Knight","raw_affiliation_strings":["Department of Chemistry, University of Colorado, Denver, CO 2"],"raw_orcid":"https://orcid.org/0000-0003-2208-4420","affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Colorado, Denver, CO 2","institution_ids":["https://openalex.org/I921990950"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041216651","display_name":"Arun Anantharam","orcid":"https://orcid.org/0000-0001-8560-6180","observed_orcids":["https://orcid.org/0000-0001-8560-6180"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Arun Anantharam","raw_affiliation_strings":["Department of Pharmacology, University of Michigan, Ann Arbor, MI 1"],"raw_orcid":"https://orcid.org/0000-0001-8560-6180","affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Michigan, Ann Arbor, MI 1","institution_ids":["https://openalex.org/I27837315"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5041216651","https://openalex.org/A5046226962"],"corresponding_institution_ids":["https://openalex.org/I27837315","https://openalex.org/I921990950"],"apc_list":null,"apc_paid":null,"fwci":0.7294,"has_fulltext":true,"cited_by_count":63,"citation_normalized_percentile":{"value":0.56643952,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"150","issue":"6","first_page":"783","last_page":"807"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13415","display_name":"Calcium signaling and nucleotide metabolism","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1314","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/synaptotagmin-7","display_name":"synaptotagmin 7","score":0.9990000128746033},{"id":"https://openalex.org/keywords/calcium-indicator","display_name":"calcium sensor","score":0.652999997138977},{"id":"https://openalex.org/keywords/regulated-exocytosis","display_name":"regulated exocytosis","score":0.9879999756813049},{"id":"https://openalex.org/keywords/synaptic-transmission","display_name":"synaptic transmission","score":0.7120000123977661},{"id":"https://openalex.org/keywords/neuroendocrine-secretion","display_name":"neuroendocrine secretion","score":0.7680000066757202},{"id":"https://openalex.org/keywords/membrane-fusion","display_name":"membrane fusion","score":0.9419999718666077},{"id":"https://openalex.org/keywords/fusion-pore-expansion","display_name":"fusion pore expansion","score":0.996999979019165},{"id":"https://openalex.org/keywords/phospholipid-binding","display_name":"phospholipid binding","score":0.902999997138977},{"id":"https://openalex.org/keywords/neurotransmitter-release","display_name":"neurotransmitter release","score":0.7519999742507935},{"id":"https://openalex.org/keywords/calcium-sensitivity","display_name":"calcium sensitivity","score":0.4059999883174896}],"concepts":[{"id":"https://openalex.org/C86473631","wikidata":"https://www.wikidata.org/wiki/Q18031809","display_name":"Synaptotagmin 1","level":5,"score":0.9552837610244751},{"id":"https://openalex.org/C175969161","wikidata":"https://www.wikidata.org/wiki/Q323426","display_name":"Exocytosis","level":3,"score":0.8554646968841553},{"id":"https://openalex.org/C2909695770","wikidata":"https://www.wikidata.org/wiki/Q426764","display_name":"Synaptotagmin I","level":5,"score":0.7087514400482178},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.608570396900177},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5517048835754395},{"id":"https://openalex.org/C103038307","wikidata":"https://www.wikidata.org/wiki/Q6556360","display_name":"Lipid bilayer fusion","level":3,"score":0.5156623125076294},{"id":"https://openalex.org/C200170125","wikidata":"https://www.wikidata.org/wiki/Q969316","display_name":"Neurotransmission","level":3,"score":0.5140477418899536},{"id":"https://openalex.org/C196330066","wikidata":"https://www.wikidata.org/wiki/Q7923216","display_name":"Vesicle fusion","level":5,"score":0.5073010325431824},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.49936366081237793},{"id":"https://openalex.org/C53728453","wikidata":"https://www.wikidata.org/wiki/Q18031771","display_name":"STX1A","level":5,"score":0.46480122208595276},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.43616488575935364},{"id":"https://openalex.org/C148785051","wikidata":"https://www.wikidata.org/wiki/Q671136","display_name":"Synaptic vesicle","level":4,"score":0.3790375888347626},{"id":"https://openalex.org/C2778256703","wikidata":"https://www.wikidata.org/wiki/Q390407","display_name":"Syntaxin","level":4,"score":0.37473708391189575},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3623502552509308},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.34700122475624084},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.34375208616256714},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.24886280298233032},{"id":"https://openalex.org/C130316041","wikidata":"https://www.wikidata.org/wiki/Q189206","display_name":"Vesicle","level":3,"score":0.2355954647064209},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.13614124059677124},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005089","descriptor_name":"Exocytosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008561","descriptor_name":"Membrane Fusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D022142","descriptor_name":"Secretory Vesicles","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D050857","descriptor_name":"Synaptotagmins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D050857","descriptor_name":"Synaptotagmins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D050857","descriptor_name":"Synaptotagmins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1085/jgp.201711944","doi":"https://doi.org/10.1085/jgp.201711944","is_oa":true,"landing_page_url":"https://doi.org/10.1085/jgp.201711944","pdf_url":"https://rupress.org/jgp/article-pdf/150/6/783/1234878/jgp_201711944.pdf","source":{"id":"https://openalex.org/S168548653","display_name":"The Journal of General Physiology","issn_l":"0022-1295","issn":["0022-1295","1540-7748"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of General Physiology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5241299","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5987875","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5987875","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5987875","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Gen Physiol","raw_type":"Text"},{"id":"pmid:29794152","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29794152","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of general physiology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1085/jgp.201711944","doi":"https://doi.org/10.1085/jgp.201711944","is_oa":true,"landing_page_url":"https://doi.org/10.1085/jgp.201711944","pdf_url":"https://rupress.org/jgp/article-pdf/150/6/783/1234878/jgp_201711944.pdf","source":{"id":"https://openalex.org/S168548653","display_name":"The Journal of General Physiology","issn_l":"0022-1295","issn":["0022-1295","1540-7748"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of General Physiology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G252996064","display_name":null,"funder_award_id":"SDG14420049","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3668247129","display_name":"Ca2+-independent and Ca2+-inhibited membrane binding by synaptotagmin-like proteins","funder_award_id":"R15GM102866","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G3735088964","display_name":null,"funder_award_id":"SDG14420049","funder_id":"https://openalex.org/F4320306230","funder_display_name":"American Heart Association"},{"id":"https://openalex.org/G4299135760","display_name":"The Impact of Synaptotagmin Isoform Structure and Diversity on Dense Core Granule Exocytosis","funder_award_id":"R01GM111997","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G55653133","display_name":null,"funder_award_id":"GM111997","funder_id":"https://openalex.org/F4320306230","funder_display_name":"American Heart Association"},{"id":"https://openalex.org/G907373125","display_name":null,"funder_award_id":"GM102866","funder_id":"https://openalex.org/F4320306230","funder_display_name":"American Heart Association"}],"funders":[{"id":"https://openalex.org/F4320306230","display_name":"American Heart Association","ror":"https://ror.org/013kjyp64"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2803294422.pdf","grobid_xml":"https://content.openalex.org/works/W2803294422.grobid-xml"},"referenced_works_count":262,"referenced_works":["https://openalex.org/W1224729583","https://openalex.org/W1418660035","https://openalex.org/W1495115482","https://openalex.org/W1496654933","https://openalex.org/W1516563030","https://openalex.org/W1564650596","https://openalex.org/W1568294354","https://openalex.org/W1591133722","https://openalex.org/W1599906730","https://openalex.org/W1650765334","https://openalex.org/W1671421450","https://openalex.org/W1702317583","https://openalex.org/W1796620477","https://openalex.org/W1822252127","https://openalex.org/W1871478100","https://openalex.org/W1871551316","https://openalex.org/W1907518241","https://openalex.org/W1913308306","https://openalex.org/W1915325285","https://openalex.org/W1921354988","https://openalex.org/W1943153345","https://openalex.org/W1964375147","https://openalex.org/W1966803885","https://openalex.org/W1966886300","https://openalex.org/W1969159701","https://openalex.org/W1969288514","https://openalex.org/W1970654974","https://openalex.org/W1970868557","https://openalex.org/W1971016259","https://openalex.org/W1975194767","https://openalex.org/W1975215899","https://openalex.org/W1975362912","https://openalex.org/W1975384164","https://openalex.org/W1975572942","https://openalex.org/W1975830464","https://openalex.org/W1975852922","https://openalex.org/W1976283234","https://openalex.org/W1978302530","https://openalex.org/W1978348407","https://openalex.org/W1979556762","https://openalex.org/W1981385619","https://openalex.org/W1981668412","https://openalex.org/W1981726470","https://openalex.org/W1982073244","https://openalex.org/W1982602254","https://openalex.org/W1982630258","https://openalex.org/W1983227007","https://openalex.org/W1984469869","https://openalex.org/W1988007470","https://openalex.org/W1988691994","https://openalex.org/W1990559120","https://openalex.org/W1990653906","https://openalex.org/W1991558060","https://openalex.org/W1991748157","https://openalex.org/W1992163176","https://openalex.org/W1992368660","https://openalex.org/W1993354797","https://openalex.org/W1993518080","https://openalex.org/W1994489140","https://openalex.org/W1995034764","https://openalex.org/W1995952267","https://openalex.org/W1996162595","https://openalex.org/W1997116271","https://openalex.org/W1997381540","https://openalex.org/W1999292981","https://openalex.org/W1999367496","https://openalex.org/W1999772445","https://openalex.org/W2000049837","https://openalex.org/W2003380714","https://openalex.org/W2003782999","https://openalex.org/W2005212070","https://openalex.org/W2005593816","https://openalex.org/W2005759534","https://openalex.org/W2006221005","https://openalex.org/W2010315760","https://openalex.org/W2010986301","https://openalex.org/W2011889479","https://openalex.org/W2011940688","https://openalex.org/W2013279676","https://openalex.org/W2013539793","https://openalex.org/W2014181207","https://openalex.org/W2015611396","https://openalex.org/W2015894821","https://openalex.org/W2016698582","https://openalex.org/W2017721231","https://openalex.org/W2017759753","https://openalex.org/W2018757497","https://openalex.org/W2020069648","https://openalex.org/W2021285837","https://openalex.org/W2022294768","https://openalex.org/W2022480984","https://openalex.org/W2023393253","https://openalex.org/W2023501012","https://openalex.org/W2023707309","https://openalex.org/W2024136850","https://openalex.org/W2025087599","https://openalex.org/W2027775552","https://openalex.org/W2029160544","https://openalex.org/W2029582401","https://openalex.org/W2030837547","https://openalex.org/W2031803152","https://openalex.org/W2031854861","https://openalex.org/W2031988397","https://openalex.org/W2032562864","https://openalex.org/W2033067408","https://openalex.org/W2033838637","https://openalex.org/W2033888271","https://openalex.org/W2035070093","https://openalex.org/W2035145343","https://openalex.org/W2035805790","https://openalex.org/W2035949357","https://openalex.org/W2035960277","https://openalex.org/W2037168572","https://openalex.org/W2037307064","https://openalex.org/W2038870054","https://openalex.org/W2040618621","https://openalex.org/W2042089363","https://openalex.org/W2043768757","https://openalex.org/W2043875151","https://openalex.org/W2044414150","https://openalex.org/W2044679183","https://openalex.org/W2047012631","https://openalex.org/W2047399603","https://openalex.org/W2048015603","https://openalex.org/W2048159584","https://openalex.org/W2048465987","https://openalex.org/W2049279140","https://openalex.org/W2049308967","https://openalex.org/W2050427247","https://openalex.org/W2051393046","https://openalex.org/W2051707340","https://openalex.org/W2052298684","https://openalex.org/W2053515408","https://openalex.org/W2053635222","https://openalex.org/W2055334158","https://openalex.org/W2057457093","https://openalex.org/W2061177753","https://openalex.org/W2063151142","https://openalex.org/W2063268584","https://openalex.org/W2067251059","https://openalex.org/W2067625723","https://openalex.org/W2068738089","https://openalex.org/W2072023677","https://openalex.org/W2075374954","https://openalex.org/W2075402444","https://openalex.org/W2076311985","https://openalex.org/W2076881120","https://openalex.org/W2077910689","https://openalex.org/W2078068750","https://openalex.org/W2078230520","https://openalex.org/W2078686355","https://openalex.org/W2079405491","https://openalex.org/W2080932989","https://openalex.org/W2080954023","https://openalex.org/W2083973947","https://openalex.org/W2085680244","https://openalex.org/W2085829343","https://openalex.org/W2086036400","https://openalex.org/W2086890785","https://openalex.org/W2088402888","https://openalex.org/W2088599346","https://openalex.org/W2089641450","https://openalex.org/W2091653401","https://openalex.org/W2093160716","https://openalex.org/W2093893801","https://openalex.org/W2094337062","https://openalex.org/W2095144685","https://openalex.org/W2096106436","https://openalex.org/W2096582689","https://openalex.org/W2098206544","https://openalex.org/W2098635427","https://openalex.org/W2099310610","https://openalex.org/W2101027975","https://openalex.org/W2101562100","https://openalex.org/W2102289204","https://openalex.org/W2103787070","https://openalex.org/W2104651163","https://openalex.org/W2105305770","https://openalex.org/W2106431604","https://openalex.org/W2106723144","https://openalex.org/W2107305007","https://openalex.org/W2107896719","https://openalex.org/W2108065590","https://openalex.org/W2108594642","https://openalex.org/W2110078708","https://openalex.org/W2112927743","https://openalex.org/W2113632335","https://openalex.org/W2113959625","https://openalex.org/W2114577396","https://openalex.org/W2115743000","https://openalex.org/W2115761121","https://openalex.org/W2119177737","https://openalex.org/W2120615966","https://openalex.org/W2121966104","https://openalex.org/W2122447021","https://openalex.org/W2123878072","https://openalex.org/W2124897951","https://openalex.org/W2125095292","https://openalex.org/W2125334454","https://openalex.org/W2126412071","https://openalex.org/W2127322768","https://openalex.org/W2128007435","https://openalex.org/W2128354083","https://openalex.org/W2128846365","https://openalex.org/W2129430733","https://openalex.org/W2136422440","https://openalex.org/W2137229430","https://openalex.org/W2140274945","https://openalex.org/W2141518284","https://openalex.org/W2142311913","https://openalex.org/W2142413646","https://openalex.org/W2142763075","https://openalex.org/W2144138755","https://openalex.org/W2147035699","https://openalex.org/W2150190558","https://openalex.org/W2151380386","https://openalex.org/W2151858671","https://openalex.org/W2152969853","https://openalex.org/W2153704874","https://openalex.org/W2153860862","https://openalex.org/W2156796661","https://openalex.org/W2158177370","https://openalex.org/W2158350205","https://openalex.org/W2161141060","https://openalex.org/W2161835786","https://openalex.org/W2164517163","https://openalex.org/W2165302477","https://openalex.org/W2167832495","https://openalex.org/W2167898988","https://openalex.org/W2168315683","https://openalex.org/W2172248769","https://openalex.org/W2200436150","https://openalex.org/W2233262349","https://openalex.org/W2235731016","https://openalex.org/W2242695760","https://openalex.org/W2312134955","https://openalex.org/W2324695254","https://openalex.org/W2345168168","https://openalex.org/W2403236229","https://openalex.org/W2422890432","https://openalex.org/W2432942911","https://openalex.org/W2495776277","https://openalex.org/W2509564619","https://openalex.org/W2540355822","https://openalex.org/W2560738186","https://openalex.org/W2572503237","https://openalex.org/W2586075733","https://openalex.org/W2610396255","https://openalex.org/W2616638744","https://openalex.org/W2731280167","https://openalex.org/W2736556855","https://openalex.org/W2749952289","https://openalex.org/W2751377163","https://openalex.org/W2751808509","https://openalex.org/W2753736324","https://openalex.org/W2756163062","https://openalex.org/W2765649616","https://openalex.org/W2771050855","https://openalex.org/W2775089136","https://openalex.org/W2776170173","https://openalex.org/W2792871254","https://openalex.org/W2794624963"],"related_works":["https://openalex.org/W3005294890","https://openalex.org/W3016217206","https://openalex.org/W2957619006","https://openalex.org/W2913419568","https://openalex.org/W3006636622","https://openalex.org/W2359816887","https://openalex.org/W2106431604","https://openalex.org/W7097437566","https://openalex.org/W4389049727","https://openalex.org/W2044512158"],"abstract_inverted_index":{"Synaptotagmin":[0],"(Syt)":[1],"proteins":[2],"comprise":[3],"a":[4,40,56,120],"17-member":[5],"family,":[6],"many":[7],"of":[8,42,46,53,59,70,79,84,90,104],"which":[9,25],"trigger":[10],"exocytosis":[11],"in":[12,32,55,72,88,126,132],"response":[13],"to":[14,122],"calcium.":[15],"Historically,":[16],"most":[17],"studies":[18],"have":[19],"focused":[20],"on":[21,101,113],"the":[22,28,65,77],"isoform":[23],"Syt-1,":[24],"serves":[26],"as":[27],"primary":[29],"calcium":[30,49],"sensor":[31],"synchronous":[33],"neurotransmitter":[34],"release.":[35],"Recently,":[36],"Syt-7":[37,71,85],"has":[38],"become":[39],"topic":[41],"broad":[43],"interest":[44],"because":[45],"its":[47,80,130],"extreme":[48],"sensitivity":[50],"and":[51,67,75,94,107,115],"diversity":[52],"roles":[54,69],"wide":[57],"range":[58],"cell":[60,109],"types.":[61],"Here,":[62],"we":[63,118],"review":[64],"known":[66],"emerging":[68],"various":[73],"contexts":[74],"stress":[76],"importance":[78],"actions.":[81],"Unique":[82],"functions":[83],"are":[86],"discussed":[87],"light":[89],"recent":[91],"imaging,":[92],"electrophysiological,":[93],"computational":[95],"studies.":[96],"Particular":[97],"emphasis":[98],"is":[99],"placed":[100],"Syt-7-dependent":[102],"regulation":[103],"synaptic":[105],"transmission":[106],"neuroendocrine":[108],"secretion.":[110],"Finally,":[111],"based":[112],"biochemical":[114],"structural":[116],"data,":[117],"propose":[119],"mechanism":[121],"link":[123],"Syt-7's":[124],"role":[125,131],"membrane":[127],"fusion":[128,134],"with":[129],"subsequent":[133],"pore":[135],"expansion":[136],"via":[137],"strong":[138],"calcium-dependent":[139],"phospholipid":[140],"binding.":[141]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":15},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-06-01T00:00:00"}
