{"id":"https://openalex.org/W2803294073","doi":null,"title":"Effectiveness of Mobile Text Messaging to Improve Schizophrenia Adherence, Symptoms and Functioning in a Resource-poor Community Setting: \u201cLEAN\u201d Randomized Controlled Trial","display_name":"Effectiveness of Mobile Text Messaging to Improve Schizophrenia Adherence, Symptoms and Functioning in a Resource-poor Community Setting: \u201cLEAN\u201d Randomized Controlled Trial","publication_year":2017,"publication_date":"2017-01-01","ids":{"openalex":"https://openalex.org/W2803294073","mag":"2803294073"},"language":"en","primary_location":{"id":"pmh:oai:digital.lib.washington.edu:1773/40805","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1773/40805","pdf_url":"http://hdl.handle.net/1773/40805","source":{"id":"https://openalex.org/S4306401128","display_name":"ResearchWorks at the University of Washington (University of Washington)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I201448701","host_organization_name":"University of Washington","host_organization_lineage":["https://openalex.org/I201448701"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/1773/40805","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050308421","display_name":"Dong Roman Xu","orcid":"https://orcid.org/0000-0001-7438-632X","observed_orcids":["https://orcid.org/0000-0001-7438-632X","https://orcid.org/0000-0002-5603-8951"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Dong Xu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5050308421"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11446","display_name":"Mobile Health and mHealth Applications","score":0.8823000192642212,"subfield":{"id":"https://openalex.org/subfields/3600","display_name":"General Health Professions"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11446","display_name":"Mobile Health and mHealth Applications","score":0.8823000192642212,"subfield":{"id":"https://openalex.org/subfields/3600","display_name":"General Health Professions"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11620","display_name":"Medication Adherence and Compliance","score":0.05550000071525574,"subfield":{"id":"https://openalex.org/subfields/2714","display_name":"Family Practice"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.015699999406933784,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.9449999928474426},{"id":"https://openalex.org/keywords/text-messaging","display_name":"text messaging","score":0.9950000047683716},{"id":"https://openalex.org/keywords/treatment-adherence","display_name":"medication adherence","score":0.9850000143051147},{"id":"https://openalex.org/keywords/relapse-prevention","display_name":"relapse prevention","score":0.9120000004768372},{"id":"https://openalex.org/keywords/hospital-readmission","display_name":"hospital readmission","score":0.7120000123977661},{"id":"https://openalex.org/keywords/social-functioning","display_name":"social functioning","score":0.6729999780654907},{"id":"https://openalex.org/keywords/community-mental-health-programs","display_name":"community mental health programs","score":0.6790000200271606},{"id":"https://openalex.org/keywords/resource-limited-settings","display_name":"resource-limited settings","score":0.9010000228881836},{"id":"https://openalex.org/keywords/rural-china","display_name":"rural China","score":0.7379999756813049},{"id":"https://openalex.org/keywords/family-caregivers","display_name":"family caregivers","score":0.574999988079071},{"id":"https://openalex.org/keywords/health-education","display_name":"health education","score":0.656000018119812},{"id":"https://openalex.org/keywords/community-dwelling-patients","display_name":"community-dwelling patients","score":0.6439999938011169},{"id":"https://openalex.org/keywords/digital-mental-health-interventions","display_name":"digital mental health interventions","score":0.5609999895095825}],"concepts":[{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.5621788501739502},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.5209804177284241},{"id":"https://openalex.org/C206345919","wikidata":"https://www.wikidata.org/wiki/Q20380951","display_name":"Resource (disambiguation)","level":2,"score":0.47695624828338623},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.46499505639076233},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4324849247932434},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.31250032782554626},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.24374878406524658},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.0980510413646698},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.09070166945457458}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:digital.lib.washington.edu:1773/40805","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1773/40805","pdf_url":"http://hdl.handle.net/1773/40805","source":{"id":"https://openalex.org/S4306401128","display_name":"ResearchWorks at the University of Washington (University of Washington)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I201448701","host_organization_name":"University of Washington","host_organization_lineage":["https://openalex.org/I201448701"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"mag:2803294073","doi":null,"is_oa":false,"landing_page_url":"https://digital.lib.washington.edu:443/researchworks/handle/1773/40805","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:digital.lib.washington.edu:1773/40805","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1773/40805","pdf_url":"http://hdl.handle.net/1773/40805","source":{"id":"https://openalex.org/S4306401128","display_name":"ResearchWorks at the University of Washington (University of Washington)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I201448701","host_organization_name":"University of Washington","host_organization_lineage":["https://openalex.org/I201448701"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2803294073.pdf","grobid_xml":"https://content.openalex.org/works/W2803294073.grobid-xml"},"referenced_works_count":106,"referenced_works":["https://openalex.org/W257923760","https://openalex.org/W837541363","https://openalex.org/W1484862639","https://openalex.org/W1505971216","https://openalex.org/W1532052933","https://openalex.org/W1541013958","https://openalex.org/W1587689776","https://openalex.org/W1594115407","https://openalex.org/W1769383559","https://openalex.org/W1771428564","https://openalex.org/W1964118658","https://openalex.org/W1964178524","https://openalex.org/W1966279941","https://openalex.org/W1972110417","https://openalex.org/W1979917389","https://openalex.org/W1982845758","https://openalex.org/W1984037815","https://openalex.org/W1984982865","https://openalex.org/W1987339736","https://openalex.org/W1991044306","https://openalex.org/W1993666933","https://openalex.org/W1993959534","https://openalex.org/W1996814006","https://openalex.org/W1998232894","https://openalex.org/W2009832071","https://openalex.org/W2011675347","https://openalex.org/W2011966535","https://openalex.org/W2013847807","https://openalex.org/W2015795623","https://openalex.org/W2016628685","https://openalex.org/W2020384208","https://openalex.org/W2021197154","https://openalex.org/W2025634432","https://openalex.org/W2027300442","https://openalex.org/W2031016856","https://openalex.org/W2031756259","https://openalex.org/W2032569390","https://openalex.org/W2033530831","https://openalex.org/W2040867604","https://openalex.org/W2045118046","https://openalex.org/W2045174493","https://openalex.org/W2048187664","https://openalex.org/W2053154970","https://openalex.org/W2059117191","https://openalex.org/W2060382984","https://openalex.org/W2063780338","https://openalex.org/W2066642377","https://openalex.org/W2066785498","https://openalex.org/W2068456588","https://openalex.org/W2070893229","https://openalex.org/W2071677184","https://openalex.org/W2081903227","https://openalex.org/W2084161315","https://openalex.org/W2086310388","https://openalex.org/W2087709083","https://openalex.org/W2087910304","https://openalex.org/W2093274439","https://openalex.org/W2097022837","https://openalex.org/W2099036273","https://openalex.org/W2100984327","https://openalex.org/W2104126672","https://openalex.org/W2105980866","https://openalex.org/W2107031757","https://openalex.org/W2110091980","https://openalex.org/W2113758182","https://openalex.org/W2116246373","https://openalex.org/W2123396453","https://openalex.org/W2124742359","https://openalex.org/W2125813823","https://openalex.org/W2127134070","https://openalex.org/W2130340268","https://openalex.org/W2132515061","https://openalex.org/W2133746099","https://openalex.org/W2135900466","https://openalex.org/W2137320167","https://openalex.org/W2137354881","https://openalex.org/W2143189599","https://openalex.org/W2143403659","https://openalex.org/W2143970799","https://openalex.org/W2145355470","https://openalex.org/W2148602524","https://openalex.org/W2148638523","https://openalex.org/W2149025975","https://openalex.org/W2150401511","https://openalex.org/W2152079931","https://openalex.org/W2154230830","https://openalex.org/W2154842668","https://openalex.org/W2155379038","https://openalex.org/W2158102674","https://openalex.org/W2158206968","https://openalex.org/W2159285055","https://openalex.org/W2159582834","https://openalex.org/W2164551392","https://openalex.org/W2168058079","https://openalex.org/W2168592380","https://openalex.org/W2287633326","https://openalex.org/W2313339984","https://openalex.org/W2316816218","https://openalex.org/W2402573949","https://openalex.org/W2419473118","https://openalex.org/W2507426356","https://openalex.org/W2518354110","https://openalex.org/W2587057510","https://openalex.org/W2596916116","https://openalex.org/W2796235691","https://openalex.org/W4247932988"],"related_works":["https://openalex.org/W3106794766","https://openalex.org/W2940899144","https://openalex.org/W2287633326","https://openalex.org/W2024834996","https://openalex.org/W3116350384","https://openalex.org/W7098367372","https://openalex.org/W2125813823","https://openalex.org/W3095180717","https://openalex.org/W2794681245","https://openalex.org/W6996739218"],"abstract_inverted_index":{"Objective":[0],"To":[1],"evaluate":[2],"the":[3,49,102,133,139,166,171,197],"effectiveness":[4],"of":[5,31,82,85,106,187,199,203,210,227,234],"mobile":[6],"text":[7,73],"messaging":[8],"to":[9,93,124,136,150,168,178,219,242],"improve":[10],"medication":[11,76,103,267],"adherence,":[12],"symptoms":[13,188],"and":[14,51,66,80,121,223,248,269,272,275],"functioning":[15,161,271],"in":[16,21,132,138,160,165,170,185,196,252,265],"community-dwelling":[17,37],"people":[18],"with":[19,40],"schizophrenia":[20],"a":[22,55,253,261],"resource-poor":[23,254],"setting.Design":[24],"Two-arm":[25],"randomized":[26,44],"controlled":[27],"trial.Setting":[28],"Rural":[29],"communities":[30],"Hunan":[32],"Province,":[33],"China.Participants":[34],"278":[35],"randomly-selected":[36],"villagers":[38],"diagnosed":[39],"schizophrenia.Interventions":[41],"Participants":[42],"were":[43],"1:1":[45],"into":[46],"two":[47],"groups.Both":[48],"intervention":[50,69,87,140,172],"control":[52,134],"groups":[53],"received":[54,72],"nation-wide":[56],"community-based":[57],"mental":[58],"health":[59,78],"program":[60,156,263],"that":[61],"provided":[62],"free":[63],"antipsychotic":[64],"medications":[65],"clinician":[67],"consultations.The":[68],"group":[70,135,141],"also":[71],"messages":[74],"for":[75],"reminders,":[77],"education":[79],"monitoring":[81],"early":[83],"signs":[84],"relapses.The":[86],"was":[88,101,189,193,257],"conducted":[89],"from":[90,130,162],"November":[91],"2015":[92],"July":[94],"2016.Main":[95],"outcome":[96,100],"measures":[97],"The":[98,155],"primary":[99],"adherence":[104,127,268],"(percentage":[105],"dosages":[107],"taken)":[108],"assessed":[109],"by":[110],"unannounced":[111],"home-based":[112],"pill-counts.The":[113],"secondary":[114],"outcomes":[115],"included":[116],"patient":[117,270],"symptoms,":[118],"functioning,":[119],"relapses,":[120],"re-hospitalization":[122],"due":[123],"schizophrenia.Results":[125],"Medication":[126],"increased":[128],"27%":[129],"0.49":[131],"0.63":[137,215],"(adjusted":[142],"mean":[143],"difference":[144,184],"(AMD)":[145],"0.13":[146],"[95%":[147,175,216],"CI":[148,176,217,240],"0.04":[149],"0.22];p=0.004;":[151],"effect":[152,181],"size":[153,182],"0.35);":[154],"showed":[157],"less":[158],"loss":[159,164],"15%":[163],"controls":[167],"12%":[169],"(AMD":[173],"-0.03":[174],"-0.07":[177],"0.01];":[179],"p=0.117;":[180],"0.17).No":[183],"severity":[186],"found,":[190],"however,":[191],"there":[192],"substantial":[194],"reduction":[195],"risks":[198],"relapses":[200,274],"(26":[201],"(21.7%)":[202],"120":[204],"interventional":[205,229],"participants":[206,230],"vs.":[207,231],"40":[208],"(34.2%)":[209],"117":[211],"controls;":[212,236],"risk":[213,237],"ratio":[214,238],"0.42":[218],"0.97];":[220],"NNT":[221,244],"8.0)":[222],"re-hospitalizations":[224],"(9":[225],"(7.3%)":[226],"123":[228],"25":[232],"(20.5%)":[233],"122":[235],"0.36[95%":[239],"0.17":[241],"0.73];":[243],"7.6).Conclusions":[245],"Texting":[246],"patients":[247],"their":[249],"family":[250],"supervisors":[251],"community":[255],"setting":[256],"more":[258],"effective":[259],"than":[260],"free-medicine":[262],"alone":[264],"improving":[266],"reducing":[273],"re-hospitalizations.":[276],"Trial":[277],"registration":[278],"ChiCTR-ICR-15006053":[279]},"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2018-06-01T00:00:00"}