{"id":"https://openalex.org/W2803290567","doi":"https://doi.org/10.1186/s13068-018-1076-1","title":"The diversity and specificity of the extracellular proteome in the cellulolytic bacterium Caldicellulosiruptor bescii is driven by the nature of the cellulosic growth substrate","display_name":"The diversity and specificity of the extracellular proteome in the cellulolytic bacterium Caldicellulosiruptor bescii is driven by the nature of the cellulosic growth substrate","publication_year":2018,"publication_date":"2018-03-23","ids":{"openalex":"https://openalex.org/W2803290567","doi":"https://doi.org/10.1186/s13068-018-1076-1","mag":"2803290567","pmid":"https://pubmed.ncbi.nlm.nih.gov/29588665","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5865380"},"language":"en","primary_location":{"id":"doi:10.1186/s13068-018-1076-1","doi":"https://doi.org/10.1186/s13068-018-1076-1","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13068-018-1076-1","pdf_url":"https://biotechnologyforbiofuels.biomedcentral.com/counter/pdf/10.1186/s13068-018-1076-1","source":{"id":"https://openalex.org/S137860580","display_name":"Biotechnology for Biofuels","issn_l":"1754-6834","issn":["1754-6834"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biotechnology for Biofuels","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://biotechnologyforbiofuels.biomedcentral.com/counter/pdf/10.1186/s13068-018-1076-1","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046377901","display_name":"Suresh Poudel","orcid":"https://orcid.org/0000-0003-2333-3556","observed_orcids":["https://orcid.org/0000-0003-2333-3556"]},"institutions":[{"id":"https://openalex.org/I1289243028","display_name":"Oak Ridge National Laboratory","ror":"https://ror.org/01qz5mb56","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289243028","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I4210159294"]},{"id":"https://openalex.org/I75027704","display_name":"University of Tennessee at Knoxville","ror":"https://ror.org/020f3ap87","country_code":"US","type":"education","lineage":["https://openalex.org/I75027704"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suresh Poudel","raw_affiliation_strings":["1Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","3BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","4Department of Genome Science and Technology, University of Tennessee, Knoxville, TN 37996 USA","Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, 37831, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","institution_ids":["https://openalex.org/I1289243028"]},{"raw_affiliation_string":"3BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","institution_ids":["https://openalex.org/I1289243028"]},{"raw_affiliation_string":"4Department of Genome Science and Technology, University of Tennessee, Knoxville, TN 37996 USA","institution_ids":["https://openalex.org/I75027704"]},{"raw_affiliation_string":"Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, 37831, USA","institution_ids":["https://openalex.org/I1289243028"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022944441","display_name":"Richard J. Giannone","orcid":"https://orcid.org/0000-0001-8551-0138","observed_orcids":["https://orcid.org/0000-0001-8551-0138"]},"institutions":[{"id":"https://openalex.org/I1289243028","display_name":"Oak Ridge National Laboratory","ror":"https://ror.org/01qz5mb56","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289243028","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I4210159294"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard J. Giannone","raw_affiliation_strings":["2Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","3BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, 37831, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","institution_ids":["https://openalex.org/I1289243028"]},{"raw_affiliation_string":"3BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","institution_ids":["https://openalex.org/I1289243028"]},{"raw_affiliation_string":"Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, 37831, USA","institution_ids":["https://openalex.org/I1289243028"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000803622","display_name":"Mirko Basen","orcid":"https://orcid.org/0000-0002-1001-9245","observed_orcids":["https://orcid.org/0000-0002-1001-9245"]},"institutions":[{"id":"https://openalex.org/I114090438","display_name":"Goethe University Frankfurt","ror":"https://ror.org/04cvxnb49","country_code":"DE","type":"education","lineage":["https://openalex.org/I114090438"]},{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Mirko Basen","raw_affiliation_strings":["5Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602 USA","6Present Address: Department of Molecular Microbiology and Bioenergetics, Institute of Molecular Biosciences, Johann Wolfgang Goethe University, Frankfurt Am Main, Germany","Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, 30602, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"5Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602 USA","institution_ids":["https://openalex.org/I165733156"]},{"raw_affiliation_string":"6Present Address: Department of Molecular Microbiology and Bioenergetics, Institute of Molecular Biosciences, Johann Wolfgang Goethe University, Frankfurt Am Main, Germany","institution_ids":["https://openalex.org/I114090438"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, 30602, USA","institution_ids":["https://openalex.org/I165733156"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008739880","display_name":"Intawat Nookaew","orcid":"https://orcid.org/0000-0001-8901-1088","observed_orcids":["https://orcid.org/0000-0001-8901-1088"]},"institutions":[{"id":"https://openalex.org/I1289243028","display_name":"Oak Ridge National Laboratory","ror":"https://ror.org/01qz5mb56","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289243028","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I4210159294"]},{"id":"https://openalex.org/I79620101","display_name":"University of Arkansas for Medical Sciences","ror":"https://ror.org/00xcryt71","country_code":"US","type":"education","lineage":["https://openalex.org/I79620101"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Intawat Nookaew","raw_affiliation_strings":["1Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","3BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","8Present Address: Department of Biomedical Informatics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205 USA","Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, 37831, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","institution_ids":["https://openalex.org/I1289243028"]},{"raw_affiliation_string":"3BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","institution_ids":["https://openalex.org/I1289243028"]},{"raw_affiliation_string":"8Present Address: Department of Biomedical Informatics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205 USA","institution_ids":["https://openalex.org/I79620101"]},{"raw_affiliation_string":"Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, 37831, USA","institution_ids":["https://openalex.org/I1289243028"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046792766","display_name":"Farris L. Poole","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1289243028","display_name":"Oak Ridge National Laboratory","ror":"https://ror.org/01qz5mb56","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289243028","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I4210159294"]},{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Farris L. Poole","raw_affiliation_strings":["3BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","5Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602 USA","BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN, 37831, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","institution_ids":["https://openalex.org/I1289243028"]},{"raw_affiliation_string":"5Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602 USA","institution_ids":["https://openalex.org/I165733156"]},{"raw_affiliation_string":"BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN, 37831, USA","institution_ids":["https://openalex.org/I1289243028"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008964909","display_name":"Robert M. Kelly","orcid":"https://orcid.org/0000-0002-0639-3592","observed_orcids":["https://orcid.org/0000-0002-0639-3592"]},"institutions":[{"id":"https://openalex.org/I1289243028","display_name":"Oak Ridge National Laboratory","ror":"https://ror.org/01qz5mb56","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289243028","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I4210159294"]},{"id":"https://openalex.org/I137902535","display_name":"North Carolina State University","ror":"https://ror.org/04tj63d06","country_code":"US","type":"education","lineage":["https://openalex.org/I137902535"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert M. Kelly","raw_affiliation_strings":["3BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","7Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC 27695 USA","BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN, 37831, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","institution_ids":["https://openalex.org/I1289243028"]},{"raw_affiliation_string":"7Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC 27695 USA","institution_ids":["https://openalex.org/I137902535"]},{"raw_affiliation_string":"BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN, 37831, USA","institution_ids":["https://openalex.org/I1289243028"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010547713","display_name":"Michael W. W. Adams","orcid":"https://orcid.org/0000-0002-9796-5014","observed_orcids":["https://orcid.org/0000-0002-9796-5014","https://orcid.org/0000-0003-0881-8870"]},"institutions":[{"id":"https://openalex.org/I1289243028","display_name":"Oak Ridge National Laboratory","ror":"https://ror.org/01qz5mb56","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289243028","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I4210159294"]},{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael W. W. Adams","raw_affiliation_strings":["3BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","5Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602 USA","BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN, 37831, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","institution_ids":["https://openalex.org/I1289243028"]},{"raw_affiliation_string":"5Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602 USA","institution_ids":["https://openalex.org/I165733156"]},{"raw_affiliation_string":"BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN, 37831, USA","institution_ids":["https://openalex.org/I1289243028"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002596998","display_name":"Robert L. Hettich","orcid":"https://orcid.org/0000-0001-7708-786X","observed_orcids":["https://orcid.org/0000-0001-7708-786X"]},"institutions":[{"id":"https://openalex.org/I1289243028","display_name":"Oak Ridge National Laboratory","ror":"https://ror.org/01qz5mb56","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289243028","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I4210159294"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Robert L. Hettich","raw_affiliation_strings":["2Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","3BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN, 37831, USA"],"raw_orcid":"https://orcid.org/0000-0001-7708-786X","affiliations":[{"raw_affiliation_string":"2Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","institution_ids":["https://openalex.org/I1289243028"]},{"raw_affiliation_string":"3BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA","institution_ids":["https://openalex.org/I1289243028"]},{"raw_affiliation_string":"BioEnergy Science Center at Oak Ridge National Laboratory, Oak Ridge, TN, 37831, USA","institution_ids":["https://openalex.org/I1289243028"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5002596998"],"corresponding_institution_ids":["https://openalex.org/I1289243028"],"apc_list":{"value":2990,"currency":"USD","value_usd":2990},"apc_paid":{"value":2990,"currency":"USD","value_usd":2990},"fwci":0.9997,"has_fulltext":true,"cited_by_count":21,"citation_normalized_percentile":{"value":0.71118445,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"11","issue":"1","first_page":"80","last_page":"80"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10171","display_name":"Biofuel production and bioconversion","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10171","display_name":"Biofuel production and bioconversion","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11617","display_name":"Enzyme Production and Characterization","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10284","display_name":"Anaerobic Digestion and Biogas Production","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2215","display_name":"Building and Construction"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/caldicellulosiruptor-bescii","display_name":"Caldicellulosiruptor bescii","score":0.9990000128746033},{"id":"https://openalex.org/keywords/extracellular-proteome","display_name":"extracellular proteome","score":0.9409999847412109},{"id":"https://openalex.org/keywords/secretome","display_name":"secretome","score":0.828000009059906},{"id":"https://openalex.org/keywords/lignocellulosic-biomass-degradation","display_name":"lignocellulose degradation","score":0.7409999966621399},{"id":"https://openalex.org/keywords/substrate-specificity","display_name":"substrate specificity","score":0.6700000166893005},{"id":"https://openalex.org/keywords/solute-binding-protein","display_name":"solute binding protein","score":0.8100000023841858},{"id":"https://openalex.org/keywords/carbohydrate-active-enzymes","display_name":"carbohydrate-active enzymes","score":0.8809999823570251},{"id":"https://openalex.org/keywords/carbohydrate-binding-module","display_name":"carbohydrate-binding module","score":0.9940000176429749},{"id":"https://openalex.org/keywords/xylan-utilization","display_name":"xylan utilization","score":0.8149999976158142},{"id":"https://openalex.org/keywords/hemicellulose","display_name":"hemicellulose","score":0.8040000200271606},{"id":"https://openalex.org/keywords/pectin","display_name":"pectin","score":0.890999972820282},{"id":"https://openalex.org/keywords/pullulanase","display_name":"pullulanase","score":0.6959999799728394},{"id":"https://openalex.org/keywords/abc-transporters","display_name":"ABC transporters","score":0.5960000157356262}],"concepts":[{"id":"https://openalex.org/C163283067","wikidata":"https://www.wikidata.org/wiki/Q1053121","display_name":"Cellulosic ethanol","level":3,"score":0.822091817855835},{"id":"https://openalex.org/C104397665","wikidata":"https://www.wikidata.org/wiki/Q860947","display_name":"Proteome","level":2,"score":0.6067806482315063},{"id":"https://openalex.org/C141603559","wikidata":"https://www.wikidata.org/wiki/Q410324","display_name":"Cellulase","level":3,"score":0.5505346655845642},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5235316753387451},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.5017399787902832},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.4655269980430603},{"id":"https://openalex.org/C2994592520","wikidata":"https://www.wikidata.org/wiki/Q5090496","display_name":"Substrate specificity","level":3,"score":0.45786646008491516},{"id":"https://openalex.org/C2779251873","wikidata":"https://www.wikidata.org/wiki/Q80294","display_name":"Cellulose","level":2,"score":0.34760069847106934},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2819783389568329},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.22218650579452515},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1324414312839508}],"mesh":[],"locations_count":7,"locations":[{"id":"doi:10.1186/s13068-018-1076-1","doi":"https://doi.org/10.1186/s13068-018-1076-1","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13068-018-1076-1","pdf_url":"https://biotechnologyforbiofuels.biomedcentral.com/counter/pdf/10.1186/s13068-018-1076-1","source":{"id":"https://openalex.org/S137860580","display_name":"Biotechnology for Biofuels","issn_l":"1754-6834","issn":["1754-6834"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biotechnology for Biofuels","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4774458","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5865380","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5865380","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5865380","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biotechnol Biofuels","raw_type":"Text"},{"id":"pmid:29588665","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29588665","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biotechnology for biofuels","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:bad7783a9a704e42bff05ecf5fa7aa86","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/bad7783a9a704e42bff05ecf5fa7aa86","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biotechnology for Biofuels, Vol 11, Iss 1, Pp 1-18 (2018)","raw_type":"article"},{"id":"pmh:oai:osti.gov:1435256","doi":null,"is_oa":false,"landing_page_url":"https://www.osti.gov/biblio/1435256","pdf_url":null,"source":{"id":"https://openalex.org/S4306402487","display_name":"OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I139351228","host_organization_name":"Office of Scientific and Technical Information","host_organization_lineage":["https://openalex.org/I139351228"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"pmh:oai:osti.gov:1618720","doi":null,"is_oa":false,"landing_page_url":"https://www.osti.gov/biblio/1618720","pdf_url":null,"source":{"id":"https://openalex.org/S4306402487","display_name":"OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I139351228","host_organization_name":"Office of Scientific and Technical Information","host_organization_lineage":["https://openalex.org/I139351228"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1186/s13068-018-1076-1","doi":"https://doi.org/10.1186/s13068-018-1076-1","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13068-018-1076-1","pdf_url":"https://biotechnologyforbiofuels.biomedcentral.com/counter/pdf/10.1186/s13068-018-1076-1","source":{"id":"https://openalex.org/S137860580","display_name":"Biotechnology for Biofuels","issn_l":"1754-6834","issn":["1754-6834"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biotechnology for Biofuels","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"},{"id":"https://openalex.org/F4320332359","display_name":"Office of Science","ror":"https://ror.org/00mmn6b08"},{"id":"https://openalex.org/F4320337509","display_name":"Biological and Environmental Research","ror":"https://ror.org/0114b2m14"},{"id":"https://openalex.org/F4320337801","display_name":"Center for Bioenergy Innovation","ror":"https://ror.org/0409bt986"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2803290567.pdf","grobid_xml":"https://content.openalex.org/works/W2803290567.grobid-xml"},"referenced_works_count":65,"referenced_works":["https://openalex.org/W4019147","https://openalex.org/W976759703","https://openalex.org/W1489178042","https://openalex.org/W1542847508","https://openalex.org/W1597678601","https://openalex.org/W1965822904","https://openalex.org/W1966401214","https://openalex.org/W1968252650","https://openalex.org/W1970384372","https://openalex.org/W1971147414","https://openalex.org/W1985988408","https://openalex.org/W1988769387","https://openalex.org/W1990222875","https://openalex.org/W1991518289","https://openalex.org/W2017389387","https://openalex.org/W2021176909","https://openalex.org/W2021654888","https://openalex.org/W2029553332","https://openalex.org/W2053573662","https://openalex.org/W2061939786","https://openalex.org/W2063121202","https://openalex.org/W2066907415","https://openalex.org/W2075968180","https://openalex.org/W2088862462","https://openalex.org/W2098413409","https://openalex.org/W2104494486","https://openalex.org/W2104817216","https://openalex.org/W2106292921","https://openalex.org/W2108929776","https://openalex.org/W2112399027","https://openalex.org/W2113321146","https://openalex.org/W2114926981","https://openalex.org/W2123886261","https://openalex.org/W2123912011","https://openalex.org/W2131538335","https://openalex.org/W2131850886","https://openalex.org/W2140780215","https://openalex.org/W2144553045","https://openalex.org/W2145576311","https://openalex.org/W2146884073","https://openalex.org/W2149595091","https://openalex.org/W2150390684","https://openalex.org/W2152414311","https://openalex.org/W2155632794","https://openalex.org/W2161952498","https://openalex.org/W2162123770","https://openalex.org/W2162595238","https://openalex.org/W2162723351","https://openalex.org/W2162792752","https://openalex.org/W2164106355","https://openalex.org/W2166989211","https://openalex.org/W2167778120","https://openalex.org/W2170617094","https://openalex.org/W2171888595","https://openalex.org/W2178043251","https://openalex.org/W2268443225","https://openalex.org/W2413190970","https://openalex.org/W2416721434","https://openalex.org/W2466118811","https://openalex.org/W2467375920","https://openalex.org/W2496760586","https://openalex.org/W2570774160","https://openalex.org/W2761798405","https://openalex.org/W2786774014","https://openalex.org/W2791151778"],"related_works":["https://openalex.org/W6958368501","https://openalex.org/W2113321146","https://openalex.org/W2070240687","https://openalex.org/W2116581415","https://openalex.org/W2021176909","https://openalex.org/W2164106355","https://openalex.org/W2127544695","https://openalex.org/W2517437032","https://openalex.org/W2756845839","https://openalex.org/W2775974305"],"abstract_inverted_index":{"Caldicellulosiruptor":[0],"bescii":[1,33,194,259,302],"is":[2],"a":[3,35,70,216,292],"thermophilic":[4],"cellulolytic":[5],"bacterium":[6],"that":[7,82,104,323],"efficiently":[8,111],"deconstructs":[9],"lignocellulosic":[10,73,308],"biomass":[11,309],"into":[12,19],"sugars,":[13],"which":[14,211],"subsequently":[15],"can":[16],"be":[17,148],"fermented":[18],"alcohols,":[20],"such":[21,127,134,228],"as":[22,69,128,135,229,235,291],"ethanol,":[23],"and":[24,46,66,91,101,114,130,137,153,156,163,182,209,215,231,244,261,272,305,312,328],"other":[25,313],"products.":[26,315],"Deconstruction":[27],"of":[28,37,72,96,256,274,288,307,320],"complex":[29,124,162],"substrates":[30,242,296],"by":[31,170],"C.":[32,193,258,301],"involves":[34],"myriad":[36],"highly":[38,185,236],"abundant,":[39],"substrate-specific":[40],"extracellular":[41,80,289,321],"solute":[42],"binding":[43,218],"proteins":[44,65,81,95,168,290,322],"(ESBPs)":[45],"carbohydrate-active":[47],"enzymes":[48,67],"(CAZymes)":[49],"containing":[50],"carbohydrate-binding":[51],"modules":[52],"(CBMs).":[53],"Mass":[54],"spectrometry-based":[55],"proteomics":[56],"was":[57,195],"employed":[58],"to":[59,85,108,147,222,280,294,298,310],"investigate":[60],"how":[61],"these":[62],"substrate":[63,224],"recognition":[64],"vary":[68],"function":[71],"substrates.":[74],"Proteomic":[75],"analysis":[76],"revealed":[77],"several":[78],"key":[79],"respond":[83],"specifically":[84],"either":[86],"C5":[87,125,164,241],"or":[88,200,285],"C6":[89],"mono-":[90],"polysaccharides.":[92],"These":[93],"include":[94],"unknown":[97],"functions":[98,140],"(PUFs),":[99],"ESBPs,":[100],"CAZymes.":[102],"ESBPs":[103],"were":[105,116,145,157,184,233],"previously":[106],"shown":[107],"interact":[109],"more":[110,159],"with":[112],"hemicellulose":[113],"pectin":[115],"detected":[117,234],"in":[118,150,161],"high":[119],"abundance":[120,287],"during":[121],"growth":[122,189],"on":[123,197,240,266],"substrates,":[126,165],"switchgrass":[129],"xylan.":[131,201],"Some":[132,226],"proteins,":[133],"Athe_0614":[136],"Athe_2368,":[138],"whose":[139],"are":[141,329],"not":[142],"well":[143],"defined":[144],"predicted":[146],"involved":[149],"xylan":[151],"utilization":[152,304],"ABC":[154],"transport":[155],"significantly":[158],"abundant":[160,186,237],"respectively.":[166],"The":[167,283],"encoded":[169],"the":[171,204,253,257,267,281],"entire":[172],"glucan":[173],"degradation":[174],"locus":[175],"(GDL;":[176],"Athe_1857,":[177],"1859,":[178],"1860,":[179],"1865,":[180],"1867,":[181],"1866)":[183],"under":[187],"all":[188],"conditions,":[190],"particularly":[191],"when":[192,238],"grown":[196,239],"cellobiose,":[198],"switchgrass,":[199],"In":[202],"contrast,":[203],"glycoside":[205],"hydrolases":[206],"Athe_0609":[207],"(Pullulanase)":[208],"0610,":[210],"both":[212],"possess":[213],"CBM20":[214],"starch":[217],"domain,":[219],"appear":[220],"preferential":[221],"C5/complex":[223],"deconstruction.":[225],"PUFs,":[227],"Athe_2463":[230],"2464,":[232],"(xylan":[243],"xylose),":[245],"also":[246],"suggesting":[247],"C5-substrate":[248],"specificity.":[249],"This":[250,316],"study":[251],"reveals":[252],"protein":[254],"membership":[255],"secretome":[260],"demonstrates":[262],"its":[263],"plasticity":[264],"based":[265],"complexity":[268],"(mono-/disaccharides":[269],"vs.":[270,277],"polysaccharides)":[271],"type":[273],"carbon":[275],"(C5":[276],"C6)":[278],"available":[279],"microorganism.":[282],"presence":[284],"increased":[286],"response":[293],"specific":[295],"helps":[297],"further":[299],"elucidate":[300],"\u2019s":[303],"conversion":[306],"biofuel":[311],"valuable":[314],"includes":[317],"improved":[318],"characterization":[319],"lack":[324],"discrete":[325],"functional":[326],"roles":[327],"poorly/not":[330],"annotated.":[331]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2018-06-01T00:00:00"}
