{"id":"https://openalex.org/W2803045681","doi":"https://doi.org/10.1080/10942912.2018.1454944","title":"Conformation change of trypsin induced by acteoside as studied using multiple spectroscopic and molecular docking methods","display_name":"Conformation change of trypsin induced by acteoside as studied using multiple spectroscopic and molecular docking methods","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2803045681","doi":"https://doi.org/10.1080/10942912.2018.1454944","mag":"2803045681"},"language":"en","primary_location":{"id":"doi:10.1080/10942912.2018.1454944","doi":"https://doi.org/10.1080/10942912.2018.1454944","is_oa":true,"landing_page_url":"https://doi.org/10.1080/10942912.2018.1454944","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/10942912.2018.1454944?needAccess=true","source":{"id":"https://openalex.org/S80488789","display_name":"International Journal of Food Properties","issn_l":"1094-2912","issn":["1094-2912","1532-2386"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315681","host_organization_name":"Marcel Dekker","host_organization_lineage":["https://openalex.org/P4310315681"],"host_organization_lineage_names":["Marcel Dekker"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Food Properties","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.tandfonline.com/doi/pdf/10.1080/10942912.2018.1454944?needAccess=true","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067828561","display_name":"Zhibing Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhibing Wu","raw_affiliation_strings":["Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University","Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University","institution_ids":["https://openalex.org/I180726961"]},{"raw_affiliation_string":"Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China","institution_ids":["https://openalex.org/I180726961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059680203","display_name":"Fengwen Huang","orcid":"https://orcid.org/0000-0002-3188-6559","observed_orcids":["https://orcid.org/0000-0002-3188-6559"]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fengwen Huang","raw_affiliation_strings":["Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University","Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University","institution_ids":["https://openalex.org/I180726961"]},{"raw_affiliation_string":"Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China","institution_ids":["https://openalex.org/I180726961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100721364","display_name":"Yutao Chen","orcid":"https://orcid.org/0000-0001-9366-7354","observed_orcids":["https://orcid.org/0000-0001-9366-7354"]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]},{"id":"https://openalex.org/I39854758","display_name":"Auckland University of Technology","ror":"https://ror.org/01zvqw119","country_code":"NZ","type":"education","lineage":["https://openalex.org/I39854758"]}],"countries":["CN","NZ"],"is_corresponding":false,"raw_author_name":"Yutao Chen","raw_affiliation_strings":["School of Science, Faculty of Health and Environmental Sciences, Auckland University of Technology","Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University","School of Science, Faculty of Health and Environmental Sciences, Auckland University of Technology, Auckland, New Zealand","Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Science, Faculty of Health and Environmental Sciences, Auckland University of Technology","institution_ids":["https://openalex.org/I39854758"]},{"raw_affiliation_string":"Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University","institution_ids":["https://openalex.org/I180726961"]},{"raw_affiliation_string":"School of Science, Faculty of Health and Environmental Sciences, Auckland University of Technology, Auckland, New Zealand","institution_ids":["https://openalex.org/I39854758"]},{"raw_affiliation_string":"Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China","institution_ids":["https://openalex.org/I180726961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017062086","display_name":"Hong Yuan Xu","orcid":"https://orcid.org/0000-0002-4730-9625","observed_orcids":["https://orcid.org/0000-0002-4730-9625"]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]},{"id":"https://openalex.org/I50760025","display_name":"Hangzhou Dianzi University","ror":"https://ror.org/0576gt767","country_code":"CN","type":"education","lineage":["https://openalex.org/I50760025"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hong Xu","raw_affiliation_strings":["Key Laboratory of RF Circuits and Systems of Ministry of Education, Hangzhou Dianzi University","Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University","Key Laboratory of RF Circuits and Systems of Ministry of Education, Hangzhou Dianzi University, Hangzhou, China","Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of RF Circuits and Systems of Ministry of Education, Hangzhou Dianzi University","institution_ids":["https://openalex.org/I50760025"]},{"raw_affiliation_string":"Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University","institution_ids":["https://openalex.org/I180726961"]},{"raw_affiliation_string":"Key Laboratory of RF Circuits and Systems of Ministry of Education, Hangzhou Dianzi University, Hangzhou, China","institution_ids":["https://openalex.org/I50760025"]},{"raw_affiliation_string":"Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China","institution_ids":["https://openalex.org/I180726961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071784970","display_name":"Manjunath D. Meti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Manjunath D. Meti","raw_affiliation_strings":["Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University","Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University","institution_ids":["https://openalex.org/I180726961"]},{"raw_affiliation_string":"Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China","institution_ids":["https://openalex.org/I180726961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101595570","display_name":"Yu Fan","orcid":"https://orcid.org/0000-0002-7379-0440","observed_orcids":["https://orcid.org/0000-0002-7379-0440"]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yu Fan","raw_affiliation_strings":["Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University","Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University","institution_ids":["https://openalex.org/I180726961"]},{"raw_affiliation_string":"Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China","institution_ids":["https://openalex.org/I180726961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055209203","display_name":"Qingguo Han","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qingguo G. Han","raw_affiliation_strings":["Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University","Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University","institution_ids":["https://openalex.org/I180726961"]},{"raw_affiliation_string":"Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China","institution_ids":["https://openalex.org/I180726961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035840666","display_name":"Haifeng Tang","orcid":"https://orcid.org/0000-0002-5073-0680","observed_orcids":["https://orcid.org/0000-0002-5073-0680"]},"institutions":[{"id":"https://openalex.org/I4210141719","display_name":"University of Hong Kong - Shenzhen Hospital","ror":"https://ror.org/047w7d678","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141719"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haifeng Tang","raw_affiliation_strings":["Department of Gynecology and Obstetrics, The University of Hong Kong-Shenzhen Hospital","Department of Gynecology and Obstetrics, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology and Obstetrics, The University of Hong Kong-Shenzhen Hospital","institution_ids":["https://openalex.org/I4210141719"]},{"raw_affiliation_string":"Department of Gynecology and Obstetrics, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China","institution_ids":["https://openalex.org/I4210141719"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055925110","display_name":"Zhendan He","orcid":"https://orcid.org/0000-0001-6876-3037","observed_orcids":["https://orcid.org/0000-0001-6876-3037"]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhendan He","raw_affiliation_strings":["School of Medicine, Shenzhen University","School of Medicine, Shenzhen University, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine, Shenzhen University","institution_ids":["https://openalex.org/I180726961"]},{"raw_affiliation_string":"School of Medicine, Shenzhen University, Shenzhen, China","institution_ids":["https://openalex.org/I180726961"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113430940","display_name":"Zhangli Hu","orcid":"https://orcid.org/0000-0002-2596-8515","observed_orcids":["https://orcid.org/0000-0002-2596-8515"]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhangli Hu","raw_affiliation_strings":["Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University","Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University","institution_ids":["https://openalex.org/I180726961"]},{"raw_affiliation_string":"Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China","institution_ids":["https://openalex.org/I180726961"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5017062086"],"corresponding_institution_ids":["https://openalex.org/I180726961","https://openalex.org/I50760025"],"apc_list":{"value":1880,"currency":"GBP","value_usd":2306},"apc_paid":{"value":1880,"currency":"GBP","value_usd":2306},"fwci":0.6244,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.62364907,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"21","issue":"1","first_page":"301","last_page":"312"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11908","display_name":"Protein Interaction Studies and Fluorescence Analysis","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11908","display_name":"Protein Interaction Studies and Fluorescence Analysis","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13539","display_name":"thermodynamics and calorimetric analyses","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/trypsin","display_name":"trypsin","score":0.9629999995231628},{"id":"https://openalex.org/keywords/verbascoside","display_name":"verbascoside","score":0.9990000128746033},{"id":"https://openalex.org/keywords/protein-ligand-binding","display_name":"protein-ligand binding","score":0.7649999856948853},{"id":"https://openalex.org/keywords/protein-conformational-change","display_name":"protein conformational change","score":0.921999990940094},{"id":"https://openalex.org/keywords/fluorescence-quenching","display_name":"fluorescence quenching","score":0.8579999804496765},{"id":"https://openalex.org/keywords/static-and-dynamic-quenching","display_name":"static and dynamic quenching","score":0.8629999756813049},{"id":"https://openalex.org/keywords/binding-thermodynamics","display_name":"binding thermodynamics","score":0.8330000042915344},{"id":"https://openalex.org/keywords/hydrophobic-interactions","display_name":"hydrophobic interactions","score":0.8790000081062317},{"id":"https://openalex.org/keywords/hydrogen-bonding","display_name":"hydrogen bonding","score":0.8709999918937683},{"id":"https://openalex.org/keywords/protein-unfolding","display_name":"protein unfolding","score":0.7260000109672546},{"id":"https://openalex.org/keywords/alpha-helix-formation","display_name":"alpha-helix formation","score":0.6669999957084656},{"id":"https://openalex.org/keywords/beta-sheet-to-alpha-helix-transition","display_name":"\u03b2-sheet to \u03b1-helix transition","score":0.7540000081062317},{"id":"https://openalex.org/keywords/molecular-docking","display_name":"molecular docking","score":0.3959999978542328}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8925222158432007},{"id":"https://openalex.org/C133571119","wikidata":"https://www.wikidata.org/wiki/Q899102","display_name":"Circular dichroism","level":2,"score":0.807847797870636},{"id":"https://openalex.org/C2780340462","wikidata":"https://www.wikidata.org/wiki/Q127450","display_name":"Trypsin","level":3,"score":0.7667140364646912},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.7059867978096008},{"id":"https://openalex.org/C112887158","wikidata":"https://www.wikidata.org/wiki/Q169324","display_name":"Hydrogen bond","level":3,"score":0.6377896666526794},{"id":"https://openalex.org/C41685203","wikidata":"https://www.wikidata.org/wiki/Q1974042","display_name":"Docking (animal)","level":2,"score":0.6293925046920776},{"id":"https://openalex.org/C121745418","wikidata":"https://www.wikidata.org/wiki/Q585536","display_name":"Quenching (fluorescence)","level":3,"score":0.5823476910591125},{"id":"https://openalex.org/C59593255","wikidata":"https://www.wikidata.org/wiki/Q901663","display_name":"Molecular dynamics","level":2,"score":0.5193599462509155},{"id":"https://openalex.org/C90260826","wikidata":"https://www.wikidata.org/wiki/Q899157","display_name":"Hydrophobic effect","level":2,"score":0.4923752546310425},{"id":"https://openalex.org/C62614982","wikidata":"https://www.wikidata.org/wiki/Q904984","display_name":"Protein secondary structure","level":2,"score":0.45768797397613525},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.4223834276199341},{"id":"https://openalex.org/C107824862","wikidata":"https://www.wikidata.org/wiki/Q616005","display_name":"Binding site","level":2,"score":0.4121079742908478},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.35919469594955444},{"id":"https://openalex.org/C147597530","wikidata":"https://www.wikidata.org/wiki/Q369472","display_name":"Computational chemistry","level":1,"score":0.2923930287361145},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.21599504351615906},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.19833135604858398},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.16934242844581604},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13411304354667664},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1080/10942912.2018.1454944","doi":"https://doi.org/10.1080/10942912.2018.1454944","is_oa":true,"landing_page_url":"https://doi.org/10.1080/10942912.2018.1454944","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/10942912.2018.1454944?needAccess=true","source":{"id":"https://openalex.org/S80488789","display_name":"International Journal of Food Properties","issn_l":"1094-2912","issn":["1094-2912","1532-2386"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315681","host_organization_name":"Marcel Dekker","host_organization_lineage":["https://openalex.org/P4310315681"],"host_organization_lineage_names":["Marcel Dekker"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Food Properties","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:830352c292e1413aae5dbebd64e4aa06","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/830352c292e1413aae5dbebd64e4aa06","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Food Properties, Vol 21, Iss 1, Pp 301-312 (2018)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1080/10942912.2018.1454944","doi":"https://doi.org/10.1080/10942912.2018.1454944","is_oa":true,"landing_page_url":"https://doi.org/10.1080/10942912.2018.1454944","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/10942912.2018.1454944?needAccess=true","source":{"id":"https://openalex.org/S80488789","display_name":"International Journal of Food Properties","issn_l":"1094-2912","issn":["1094-2912","1532-2386"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315681","host_organization_name":"Marcel Dekker","host_organization_lineage":["https://openalex.org/P4310315681"],"host_organization_lineage_names":["Marcel Dekker"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Food Properties","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2636648773","display_name":null,"funder_award_id":"30570421","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2706603104","display_name":null,"funder_award_id":"31540012","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3976915177","display_name":null,"funder_award_id":"31470431","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2803045681.pdf"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W1606364171","https://openalex.org/W1946640588","https://openalex.org/W1973387903","https://openalex.org/W1979123329","https://openalex.org/W1981050317","https://openalex.org/W1982714553","https://openalex.org/W1983660868","https://openalex.org/W1986559446","https://openalex.org/W1988258179","https://openalex.org/W1989950183","https://openalex.org/W1990653781","https://openalex.org/W1992269014","https://openalex.org/W1999552836","https://openalex.org/W2007295390","https://openalex.org/W2007711377","https://openalex.org/W2008738471","https://openalex.org/W2009351040","https://openalex.org/W2021980081","https://openalex.org/W2022214418","https://openalex.org/W2028606216","https://openalex.org/W2030399672","https://openalex.org/W2045111137","https://openalex.org/W2046694048","https://openalex.org/W2062939164","https://openalex.org/W2065448725","https://openalex.org/W2076148156","https://openalex.org/W2081255141","https://openalex.org/W2091162401","https://openalex.org/W2098441527","https://openalex.org/W2117214006","https://openalex.org/W2263677373","https://openalex.org/W2300647028","https://openalex.org/W2317231076","https://openalex.org/W2319920652","https://openalex.org/W2321837695","https://openalex.org/W2519628564","https://openalex.org/W2561525390","https://openalex.org/W2562044373","https://openalex.org/W2769279550","https://openalex.org/W4230420589","https://openalex.org/W4243445896","https://openalex.org/W4252479540"],"related_works":["https://openalex.org/W1981050317","https://openalex.org/W2885016696","https://openalex.org/W3048253136","https://openalex.org/W2944157701","https://openalex.org/W790067300","https://openalex.org/W3032904761","https://openalex.org/W4389570447","https://openalex.org/W1946640588","https://openalex.org/W4387826191","https://openalex.org/W2900597287"],"abstract_inverted_index":{"The":[0,23,44,75],"interaction":[1,120],"of":[2,33,47,64,81,121,131,177,192,204],"trypsin":[3,34,50,124],"with":[4,19,112,123,135],"acteoside":[5,28,48,122,193],"was":[6,52,67,101],"studied":[7],"using":[8],"ultraviolet":[9],"visible":[10],"absorption,":[11],"fluorescence,":[12,14],"synchronous":[13,109],"circular":[15,113],"dichroism":[16,114],"techniques,":[17],"along":[18],"molecular":[20,158],"docking":[21,154,159],"method.":[22],"fluorescence":[24,32,110],"experiments":[25],"indicated":[26,96],"that":[27,97,118,163],"quenched":[29],"the":[30,62,71,82,98,102,119,132,157,175,178,195,202,205,208],"intrinsic":[31],"via":[35],"a":[36,127],"combined":[37],"quenching":[38],"process":[39,84],"(static":[40],"and":[41,61,79,89,129,150,198],"dynamic":[42],"quenching).":[43],"binding":[45,65,83],"constant":[46],"to":[49,126,188,201,211],"obtained":[51],"2.50":[53],"\u00d7":[54],"105":[55],"L":[56],"mol\u22121":[57,88,92],"at":[58],"298":[59],"K":[60],"number":[63],"site":[66],"about":[68],"one":[69],"under":[70],"same":[72],"experimental":[73,146],"condition.":[74],"thermodynamic":[76],"functions":[77],"\u0394H\u00b0":[78],"\u0394S\u00b0":[80],"were":[85,148],"8.79":[86],"kJ":[87],"132.58":[90],"J":[91],"K\u22121,":[93],"respectively,":[94],"which":[95],"hydrophobic":[99,165],"force":[100,105],"main":[103],"acting":[104],"between":[106],"them.":[107],"Ultraviolet\u2013visible,":[108],"together":[111],"spectra":[115],"studies":[116],"demonstrated":[117],"lead":[125],"loosening":[128],"unfolding":[130],"protein":[133],"backbone":[134],"partial":[136],"\u03b2-sheet":[137],"structures":[138],"being":[139],"transformed":[140],"into":[141],"\u03b1-helix":[142],"structures.":[143],"All":[144],"these":[145],"results":[147,160],"validated":[149],"explained":[151],"reasonably":[152],"by":[153],"studies.":[155],"And":[156],"further":[161],"illustrated":[162],"besides":[164],"forces,":[166],"hydrogen":[167],"bonds":[168],"also":[169],"played":[170],"an":[171],"important":[172],"role":[173],"in":[174,194],"stabilization":[176],"acteoside\u2013trypsin":[179],"complex.":[180],"Results":[181],"from":[182],"this":[183],"study":[184],"should":[185],"be":[186,199],"helpful":[187],"make":[189],"full":[190],"use":[191],"food":[196],"industry":[197],"useful":[200],"design":[203],"drugs":[206],"for":[207],"diseases":[209],"related":[210],"trypsin.":[212]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":3}],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2018-05-17T00:00:00"}
