{"id":"https://openalex.org/W2802540109","doi":"https://doi.org/10.1515/cclm-2018-0239","title":"Analysis of protein glycation in human fingernail clippings with near-infrared (NIR) spectroscopy as an alternative technique for the diagnosis of diabetes mellitus","display_name":"Analysis of protein glycation in human fingernail clippings with near-infrared (NIR) spectroscopy as an alternative technique for the diagnosis of diabetes mellitus","publication_year":2018,"publication_date":"2018-05-11","ids":{"openalex":"https://openalex.org/W2802540109","doi":"https://doi.org/10.1515/cclm-2018-0239","mag":"2802540109","pmid":"https://pubmed.ncbi.nlm.nih.gov/29750643"},"language":"en","primary_location":{"id":"doi:10.1515/cclm-2018-0239","doi":"https://doi.org/10.1515/cclm-2018-0239","is_oa":true,"landing_page_url":"https://doi.org/10.1515/cclm-2018-0239","pdf_url":"https://www.degruyter.com/downloadpdf/journals/cclm/56/9/article-p1551.pdf","source":{"id":"https://openalex.org/S124948411","display_name":"Clinical Chemistry and Laboratory Medicine (CCLM)","issn_l":"1434-6621","issn":["1434-6621","1437-4331"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Chemistry and Laboratory Medicine (CCLM)","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.degruyter.com/downloadpdf/journals/cclm/56/9/article-p1551.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056763738","display_name":"Tinne Monteyne","orcid":"https://orcid.org/0000-0002-6743-3973","observed_orcids":["https://orcid.org/0000-0002-6743-3973"]},"institutions":[{"id":"https://openalex.org/I2801227569","display_name":"Ghent University Hospital","ror":"https://ror.org/00xmkp704","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2801227569"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Tinne Monteyne","raw_affiliation_strings":["Department of Clinical Chemistry , Ghent University Hospital , Ghent , Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Chemistry , Ghent University Hospital , Ghent , Belgium","institution_ids":["https://openalex.org/I2801227569"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016209329","display_name":"Renaat Coopman","orcid":"https://orcid.org/0000-0002-0580-9074","observed_orcids":["https://orcid.org/0000-0002-0580-9074"]},"institutions":[{"id":"https://openalex.org/I2801227569","display_name":"Ghent University Hospital","ror":"https://ror.org/00xmkp704","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2801227569"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Renaat Coopman","raw_affiliation_strings":["Department of Clinical Chemistry , Ghent University Hospital , Ghent , Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Chemistry , Ghent University Hospital , Ghent , Belgium","institution_ids":["https://openalex.org/I2801227569"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056734999","display_name":"Antoine Sadiki Kishabongo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210124924","display_name":"Universit\u00e9 Catholique de Bukavu","ror":"https://ror.org/03cg80535","country_code":"CD","type":"education","lineage":["https://openalex.org/I4210124924"]}],"countries":["CD"],"is_corresponding":false,"raw_author_name":"Antoine S. Kishabongo","raw_affiliation_strings":["Department of Laboratory Medicine , Catholic University of Bukavu , Bukavu , Democratic Republic of the Congo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine , Catholic University of Bukavu , Bukavu , Democratic Republic of the Congo","institution_ids":["https://openalex.org/I4210124924"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041837811","display_name":"Jonas Himpe","orcid":"https://orcid.org/0000-0003-0764-9833","observed_orcids":["https://orcid.org/0000-0003-0764-9833"]},"institutions":[{"id":"https://openalex.org/I2801227569","display_name":"Ghent University Hospital","ror":"https://ror.org/00xmkp704","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2801227569"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Jonas Himpe","raw_affiliation_strings":["Department of Clinical Chemistry , Ghent University Hospital , Ghent , Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Chemistry , Ghent University Hospital , Ghent , Belgium","institution_ids":["https://openalex.org/I2801227569"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004357718","display_name":"Bruno Lapauw","orcid":"https://orcid.org/0000-0002-1584-4965","observed_orcids":["https://orcid.org/0000-0002-1584-4965"]},"institutions":[{"id":"https://openalex.org/I2801227569","display_name":"Ghent University Hospital","ror":"https://ror.org/00xmkp704","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2801227569"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Bruno Lapauw","raw_affiliation_strings":["Department of Endocrinology , Ghent University Hospital , Ghent , Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology , Ghent University Hospital , Ghent , Belgium","institution_ids":["https://openalex.org/I2801227569"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076566992","display_name":"Samyah Shadid","orcid":"https://orcid.org/0000-0002-6601-0944","observed_orcids":["https://orcid.org/0000-0002-6601-0944"]},"institutions":[{"id":"https://openalex.org/I2801227569","display_name":"Ghent University Hospital","ror":"https://ror.org/00xmkp704","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2801227569"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Samyah Shadid","raw_affiliation_strings":["Department of Endocrinology , Ghent University Hospital , Ghent , Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology , Ghent University Hospital , Ghent , Belgium","institution_ids":["https://openalex.org/I2801227569"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007892327","display_name":"Elisabeth Van Aken","orcid":"https://orcid.org/0000-0003-2418-701X","observed_orcids":["https://orcid.org/0000-0003-2418-701X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elisabeth H. Van Aken","raw_affiliation_strings":["Department of Ophthalmology , Sint-Elisabeth Ziekenhuis , Zottegem , Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology , Sint-Elisabeth Ziekenhuis , Zottegem , Belgium","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065941009","display_name":"Darja Berenson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801227569","display_name":"Ghent University Hospital","ror":"https://ror.org/00xmkp704","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2801227569"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Darja Berenson","raw_affiliation_strings":["Department of Clinical Chemistry , Ghent University Hospital , Ghent , Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Chemistry , Ghent University Hospital , Ghent , Belgium","institution_ids":["https://openalex.org/I2801227569"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019072577","display_name":"Marijn M. Speeckaert","orcid":"https://orcid.org/0000-0001-9183-4390","observed_orcids":["https://orcid.org/0000-0001-9183-4390"]},"institutions":[{"id":"https://openalex.org/I2801227569","display_name":"Ghent University Hospital","ror":"https://ror.org/00xmkp704","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2801227569"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Marijn M. Speeckaert","raw_affiliation_strings":["Department of Nephrology , Ghent University Hospital , Ghent , Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology , Ghent University Hospital , Ghent , Belgium","institution_ids":["https://openalex.org/I2801227569"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030362122","display_name":"Thomas De Beer","orcid":"https://orcid.org/0000-0001-6296-0443","observed_orcids":["https://orcid.org/0000-0001-6296-0443"]},"institutions":[{"id":"https://openalex.org/I32597200","display_name":"Ghent University","ror":"https://ror.org/00cv9y106","country_code":"BE","type":"education","lineage":["https://openalex.org/I32597200"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Thomas De Beer","raw_affiliation_strings":["Department of Process Analytical Technology , Ghent University , Department of Pharmaceutical Sciences , Ghent , Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Process Analytical Technology , Ghent University , Department of Pharmaceutical Sciences , Ghent , Belgium","institution_ids":["https://openalex.org/I32597200"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5105367671","display_name":"Joris R. Delanghe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801227569","display_name":"Ghent University Hospital","ror":"https://ror.org/00xmkp704","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2801227569"]}],"countries":["BE"],"is_corresponding":true,"raw_author_name":"Joris R. Delanghe","raw_affiliation_strings":["Department of Clinical Chemistry , Ghent University Hospital , Ghent , Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Chemistry , Ghent University Hospital , Ghent , Belgium","institution_ids":["https://openalex.org/I2801227569"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5105367671"],"corresponding_institution_ids":["https://openalex.org/I2801227569"],"apc_list":{"value":2400,"currency":"EUR","value_usd":2712},"apc_paid":null,"fwci":2.4515,"has_fulltext":true,"cited_by_count":38,"citation_normalized_percentile":{"value":0.8998396,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"56","issue":"9","first_page":"1551","last_page":"1558"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.7573000192642212,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.7573000192642212,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10640","display_name":"Spectroscopy and Chemometric Analyses","score":0.22460000216960907,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":0.014299999922513962,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/protein-glycation","display_name":"protein glycation","score":0.8659999966621399},{"id":"https://openalex.org/keywords/diabetes-diagnosis","display_name":"diabetes diagnosis","score":0.9139999747276306},{"id":"https://openalex.org/keywords/near-infrared-spectroscopy","display_name":"near-infrared spectroscopy","score":0.9129999876022339},{"id":"https://openalex.org/keywords/non-invasive-diagnosis","display_name":"non-invasive diagnosis","score":0.7950000166893005},{"id":"https://openalex.org/keywords/in-vitro-glycation","display_name":"in vitro glycation","score":0.6830000281333923},{"id":"https://openalex.org/keywords/spectral-classification","display_name":"spectral classification","score":0.574999988079071},{"id":"https://openalex.org/keywords/partial-least-squares-discriminant-analysis","display_name":"PLS-DA","score":0.8119999766349792}],"concepts":[{"id":"https://openalex.org/C147990577","wikidata":"https://www.wikidata.org/wiki/Q25790","display_name":"Glycation","level":3,"score":0.791176438331604},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6266006827354431},{"id":"https://openalex.org/C43571822","wikidata":"https://www.wikidata.org/wiki/Q599037","display_name":"Near-infrared spectroscopy","level":2,"score":0.6201874613761902},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4992556571960449},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.44429445266723633},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36361509561538696},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3229460120201111},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.18797597289085388},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11441659927368164},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003920","descriptor_name":"Diabetes Mellitus","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006031","descriptor_name":"Glycosylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007633","descriptor_name":"Keratins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007633","descriptor_name":"Keratins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007633","descriptor_name":"Keratins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009262","descriptor_name":"Nails","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016002","descriptor_name":"Discriminant Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016018","descriptor_name":"Least-Squares Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017127","descriptor_name":"Glycation End Products, Advanced","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D017127","descriptor_name":"Glycation End Products, Advanced","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D019265","descriptor_name":"Spectroscopy, Near-Infrared","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1515/cclm-2018-0239","doi":"https://doi.org/10.1515/cclm-2018-0239","is_oa":true,"landing_page_url":"https://doi.org/10.1515/cclm-2018-0239","pdf_url":"https://www.degruyter.com/downloadpdf/journals/cclm/56/9/article-p1551.pdf","source":{"id":"https://openalex.org/S124948411","display_name":"Clinical Chemistry and Laboratory Medicine (CCLM)","issn_l":"1434-6621","issn":["1434-6621","1437-4331"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Chemistry and Laboratory Medicine (CCLM)","raw_type":"journal-article"},{"id":"pmid:29750643","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29750643","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical chemistry and laboratory medicine","raw_type":"Journal Article"},{"id":"pmh:oai:archive.ugent.be:8569521","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1854/LU-8569521","pdf_url":null,"source":{"id":"https://openalex.org/S4306400478","display_name":"Ghent University Academic Bibliography (Ghent University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I32597200","host_organization_name":"Ghent University","host_organization_lineage":["https://openalex.org/I32597200"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 1434-6621","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1515/cclm-2018-0239","doi":"https://doi.org/10.1515/cclm-2018-0239","is_oa":true,"landing_page_url":"https://doi.org/10.1515/cclm-2018-0239","pdf_url":"https://www.degruyter.com/downloadpdf/journals/cclm/56/9/article-p1551.pdf","source":{"id":"https://openalex.org/S124948411","display_name":"Clinical Chemistry and Laboratory Medicine (CCLM)","issn_l":"1434-6621","issn":["1434-6621","1437-4331"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Chemistry and Laboratory Medicine (CCLM)","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2802540109.pdf","grobid_xml":"https://content.openalex.org/works/W2802540109.grobid-xml"},"referenced_works_count":23,"referenced_works":["https://openalex.org/W103829666","https://openalex.org/W1533833529","https://openalex.org/W1542860649","https://openalex.org/W1563946068","https://openalex.org/W1976866098","https://openalex.org/W1979607046","https://openalex.org/W1993377606","https://openalex.org/W2010211971","https://openalex.org/W2012358846","https://openalex.org/W2039852889","https://openalex.org/W2059481799","https://openalex.org/W2062727884","https://openalex.org/W2076905584","https://openalex.org/W2083259132","https://openalex.org/W2089210920","https://openalex.org/W2101945216","https://openalex.org/W2161110363","https://openalex.org/W2168652720","https://openalex.org/W2419020699","https://openalex.org/W2516006131","https://openalex.org/W2616009730","https://openalex.org/W2700548279","https://openalex.org/W3021510377"],"related_works":["https://openalex.org/W2022432776","https://openalex.org/W2516006131","https://openalex.org/W2101945216","https://openalex.org/W4405004998","https://openalex.org/W4392003359","https://openalex.org/W7129069506","https://openalex.org/W4408326055","https://openalex.org/W4412468294","https://openalex.org/W2154936249","https://openalex.org/W2071317968"],"abstract_inverted_index":{"BACKGROUND:":[0],"Glycated":[1],"keratin":[2],"allows":[3],"the":[4,15,83,88,92,96,166,171,211,214,244],"monitoring":[5],"of":[6,43,62,64,85,95,165,170,213,227,246],"average":[7],"tissue":[8],"glucose":[9,79,86],"exposure":[10],"over":[11],"previous":[12],"weeks.":[13],"In":[14,134],"present":[16],"study,":[17],"we":[18],"wanted":[19],"to":[20,81,179,186],"explore":[21],"if":[22],"near-infrared":[23],"(NIR)":[24,112],"spectroscopy":[25,236],"could":[26,237],"be":[27,187,238],"used":[28],"as":[29],"a":[30,101,181,222],"non-invasive":[31],"diagnostic":[32],"tool":[33],"for":[34,210,243],"assessing":[35],"glycation":[36,136,229],"in":[37,55,69,138,177,230],"diabetes":[38,47,119,247],"mellitus.":[39,248],"METHODS:":[40],"A":[41,58],"total":[42],"52":[44],"patients":[45,97],"with":[46,71,118,217,234],"mellitus":[48,120],"and":[49,76,109,143,146,152,155,205],"107":[50],"healthy":[51,65,122],"subjects":[52,66],"were":[53,67,98],"enrolled":[54],"this":[56],"study.":[57],"limited":[59],"number":[60],"(n=21)":[61],"nails":[63],"glycated":[68],"vitro":[70,135],"0.278":[72],"mol/L,":[73],"0.556":[74],"mol/L":[75,78],"0.833":[77],"solution":[80],"study":[82],"effect":[84],"on":[87],"nail":[89,93],"spectrum.":[90],"Consequently,":[91],"clippings":[94,233],"analyzed":[99],"using":[100,126],"Thermo":[102],"Fisher":[103],"Antaris":[104],"II":[105],"Near-IR":[106],"Analyzer":[107],"Spectrometer":[108],"near":[110],"infrared":[111],"chemical":[113],"imaging.":[114],"Spectral":[115],"classification":[116],"(patients":[117],"vs.":[121],"subjects)":[123],"was":[124,175],"performed":[125],"partial":[127],"least":[128],"square":[129],"discriminant":[130],"analysis":[131,164],"(PLS-DA).":[132],"RESULTS:":[133],"resulted":[137],"peak":[139],"sharpening":[140],"between":[141,153],"4300":[142],"4400":[144],"cm-1":[145,151],"spectral":[147,161,172],"variations":[148],"at":[149,189],"5270":[150],"6600":[154],"7500":[156],"cm-1.":[157,196],"Similar":[158],"regions":[159],"encountered":[160],"deviations":[162],"during":[163],"patients'":[167],"nails.":[168],"Optimization":[169],"collection":[173],"parameters":[174],"necessary":[176],"order":[178],"distinguish":[180],"large":[182],"dataset.":[183],"Spectra":[184],"had":[185],"collected":[188],"16":[190],"cm-1,":[191],"128":[192],"scans,":[193],"region":[194],"4000-7500":[195],"Using":[197],"standard":[198],"normal":[199],"variate,":[200],"Savitsky-Golay":[201],"smoothing":[202],"(7":[203],"points)":[204],"first":[206],"derivative":[207],"preprocessing":[208],"allowed":[209],"prediction":[212],"test":[215],"set":[216],"100%":[218],"correct":[219],"assignments":[220],"utilizing":[221],"PLS-DA":[223],"model.":[224],"CONCLUSIONS:":[225],"Analysis":[226],"protein":[228],"human":[231],"fingernail":[232],"NIR":[235],"an":[239],"alternative":[240],"affordable":[241],"technique":[242],"diagnosis":[245]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2018-05-17T00:00:00"}