{"id":"https://openalex.org/W2802239381","doi":"https://doi.org/10.14800/ccm.1630","title":"Scaling up to study brca2: the zeppelin zebrafish mutant reveals a role for brca2 in embryonic development of kidney mesoderm","display_name":"Scaling up to study brca2: the zeppelin zebrafish mutant reveals a role for brca2 in embryonic development of kidney mesoderm","publication_year":2018,"publication_date":"2018-05-21","ids":{"openalex":"https://openalex.org/W2802239381","doi":"https://doi.org/10.14800/ccm.1630","mag":"2802239381","pmid":"https://pubmed.ncbi.nlm.nih.gov/29707605","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5922780"},"language":"en","primary_location":{"id":"doi:10.14800/ccm.1630","doi":"https://doi.org/10.14800/ccm.1630","is_oa":false,"landing_page_url":"https://doi.org/10.14800/ccm.1630","pdf_url":null,"source":{"id":"https://openalex.org/S2764763230","display_name":"Cancer Cell & Microenvironment","issn_l":"2331-091X","issn":["2331-091X","2331-0928"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310315843","host_organization_name":"Smart Science & Technology LLC, USA","host_organization_lineage":["https://openalex.org/P4310315843"],"host_organization_lineage_names":["Smart Science & Technology LLC, USA"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Cell & Microenvironment","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5922780","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110628494","display_name":"Bridgette E. Drummond","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107639228","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43","country_code":"US","type":"education","lineage":["https://openalex.org/I107639228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bridgette E Drummond","raw_affiliation_strings":["Department of Biological Sciences, Center for Stem Cells and Regenerative Medicine, Center for Zebrafish Research, University of Notre Dame, Notre Dame, IN, 46556, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Center for Stem Cells and Regenerative Medicine, Center for Zebrafish Research, University of Notre Dame, Notre Dame, IN, 46556, USA","institution_ids":["https://openalex.org/I107639228"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086699590","display_name":"Rebecca A. Wingert","orcid":"https://orcid.org/0000-0003-3133-7549","observed_orcids":["https://orcid.org/0000-0003-3133-7549"]},"institutions":[{"id":"https://openalex.org/I107639228","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43","country_code":"US","type":"education","lineage":["https://openalex.org/I107639228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rebecca A Wingert","raw_affiliation_strings":["Department of Biological Sciences, Center for Stem Cells and Regenerative Medicine, Center for Zebrafish Research, University of Notre Dame, Notre Dame, IN, 46556, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Center for Stem Cells and Regenerative Medicine, Center for Zebrafish Research, University of Notre Dame, Notre Dame, IN, 46556, USA","institution_ids":["https://openalex.org/I107639228"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I107639228"],"apc_list":null,"apc_paid":null,"fwci":0.6926,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.64529466,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"4","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11685","display_name":"Zebrafish Biomedical Research Applications","score":0.8057000041007996,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11685","display_name":"Zebrafish Biomedical Research Applications","score":0.8057000041007996,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12140","display_name":"Renal and related cancers","score":0.10490000247955322,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.07620000094175339,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brca2","display_name":"BRCA2","score":0.878000020980835},{"id":"https://openalex.org/keywords/zebrafish","display_name":"zebrafish","score":0.9559999704360962},{"id":"https://openalex.org/keywords/embryonic-development","display_name":"embryonic development","score":0.9620000123977661},{"id":"https://openalex.org/keywords/kidney-development","display_name":"kidney development","score":0.7900000214576721},{"id":"https://openalex.org/keywords/kidney-disease","display_name":"kidney disease","score":0.5559999942779541},{"id":"https://openalex.org/keywords/dna-repair","display_name":"DNA repair","score":0.39100000262260437}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8071434497833252},{"id":"https://openalex.org/C2777146197","wikidata":"https://www.wikidata.org/wiki/Q138912","display_name":"Podocyte","level":4,"score":0.7794917225837708},{"id":"https://openalex.org/C2776878037","wikidata":"https://www.wikidata.org/wiki/Q169444","display_name":"Zebrafish","level":3,"score":0.753950297832489},{"id":"https://openalex.org/C2777632694","wikidata":"https://www.wikidata.org/wiki/Q2336077","display_name":"Kidney development","level":4,"score":0.5487734079360962},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5048330426216125},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.4961260259151459},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.46528640389442444},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.45929425954818726},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.451959490776062},{"id":"https://openalex.org/C173396325","wikidata":"https://www.wikidata.org/wiki/Q1501275","display_name":"Gene knockdown","level":3,"score":0.4406873881816864},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.324239581823349},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.23699375987052917},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.23556354641914368},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.07259213924407959},{"id":"https://openalex.org/C2779561371","wikidata":"https://www.wikidata.org/wiki/Q570197","display_name":"Proteinuria","level":3,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.14800/ccm.1630","doi":"https://doi.org/10.14800/ccm.1630","is_oa":false,"landing_page_url":"https://doi.org/10.14800/ccm.1630","pdf_url":null,"source":{"id":"https://openalex.org/S2764763230","display_name":"Cancer Cell & Microenvironment","issn_l":"2331-091X","issn":["2331-091X","2331-0928"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310315843","host_organization_name":"Smart Science & Technology LLC, USA","host_organization_lineage":["https://openalex.org/P4310315843"],"host_organization_lineage_names":["Smart Science & Technology LLC, USA"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Cell & Microenvironment","raw_type":"journal-article"},{"id":"pmid:29707605","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29707605","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer cell & microenvironment","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:4842592","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5922780","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5922780","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5922780","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Cancer Cell Microenviron","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:4842592","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5922780","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G5035329252","display_name":"Generation of novel models of kidney defects using the zebrafish","funder_award_id":"R01DK100237","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":90,"referenced_works":["https://openalex.org/W107082892","https://openalex.org/W123663780","https://openalex.org/W179665357","https://openalex.org/W1505251743","https://openalex.org/W1533798237","https://openalex.org/W1535846504","https://openalex.org/W1542528220","https://openalex.org/W1615535881","https://openalex.org/W1929113708","https://openalex.org/W1940719121","https://openalex.org/W1956764277","https://openalex.org/W1957808694","https://openalex.org/W1965848563","https://openalex.org/W1970861835","https://openalex.org/W1981239255","https://openalex.org/W1983939518","https://openalex.org/W1984377389","https://openalex.org/W1988571905","https://openalex.org/W1988690189","https://openalex.org/W1990484548","https://openalex.org/W2007500392","https://openalex.org/W2008014843","https://openalex.org/W2013782514","https://openalex.org/W2020090609","https://openalex.org/W2021773963","https://openalex.org/W2027035650","https://openalex.org/W2027097760","https://openalex.org/W2028746017","https://openalex.org/W2036716410","https://openalex.org/W2048296559","https://openalex.org/W2049689768","https://openalex.org/W2057388700","https://openalex.org/W2061266562","https://openalex.org/W2064422983","https://openalex.org/W2065164670","https://openalex.org/W2071176826","https://openalex.org/W2071920387","https://openalex.org/W2073171984","https://openalex.org/W2083097467","https://openalex.org/W2083544140","https://openalex.org/W2085720101","https://openalex.org/W2088023170","https://openalex.org/W2091350790","https://openalex.org/W2092946806","https://openalex.org/W2092950132","https://openalex.org/W2096548531","https://openalex.org/W2097482160","https://openalex.org/W2098135409","https://openalex.org/W2098368760","https://openalex.org/W2101904315","https://openalex.org/W2107658397","https://openalex.org/W2120636655","https://openalex.org/W2124726835","https://openalex.org/W2125349610","https://openalex.org/W2130151956","https://openalex.org/W2132680888","https://openalex.org/W2135236140","https://openalex.org/W2140264424","https://openalex.org/W2151367032","https://openalex.org/W2152976830","https://openalex.org/W2154801237","https://openalex.org/W2164705615","https://openalex.org/W2179672927","https://openalex.org/W2281044714","https://openalex.org/W2288308260","https://openalex.org/W2301340697","https://openalex.org/W2301952476","https://openalex.org/W2329527043","https://openalex.org/W2340310434","https://openalex.org/W2401258828","https://openalex.org/W2415440329","https://openalex.org/W2464103346","https://openalex.org/W2490076080","https://openalex.org/W2508524924","https://openalex.org/W2538248451","https://openalex.org/W2552380978","https://openalex.org/W2565129115","https://openalex.org/W2570138915","https://openalex.org/W2599611426","https://openalex.org/W2602896167","https://openalex.org/W2604316693","https://openalex.org/W2604876648","https://openalex.org/W2606900274","https://openalex.org/W2615332104","https://openalex.org/W2620613559","https://openalex.org/W2621196449","https://openalex.org/W2675278942","https://openalex.org/W2754402357","https://openalex.org/W2769397480","https://openalex.org/W4211006558"],"related_works":["https://openalex.org/W2620613559","https://openalex.org/W4226076333","https://openalex.org/W2613451739","https://openalex.org/W3001373451","https://openalex.org/W2109872532","https://openalex.org/W2104963021","https://openalex.org/W2030265507","https://openalex.org/W2278687291","https://openalex.org/W3129778149","https://openalex.org/W2061538650"],"abstract_inverted_index":{"contributes":[0],"to":[1],"the":[2,7],"development":[3],"of":[4],"tissues":[5],"including":[6],"kidney":[8],"mesoderm-roles":[9],"which":[10],"may":[11],"have":[12],"implications":[13],"for":[14],"renal":[15],"diseases":[16],"as":[17],"well.":[18]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2018-05-17T00:00:00"}