{"id":"https://openalex.org/W2801569260","doi":null,"title":"Guidelines for the treatment of neuropathic pain in South Africa","display_name":"Guidelines for the treatment of neuropathic pain in South Africa","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2801569260","mag":"2801569260"},"language":"en","primary_location":{"id":"mag:2801569260","doi":null,"is_oa":false,"landing_page_url":"http://sapj.co.za/index.php/SAPJ/article/download/2558/5030","pdf_url":null,"source":{"id":"https://openalex.org/S4306530482","display_name":"South African Pharmaceutical Journal","issn_l":"0257-8719","issn":["0257-8719"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"South African Pharmaceutical Journal","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025845974","display_name":"Sonal Patel","orcid":"https://orcid.org/0000-0002-2012-8066","observed_orcids":["https://orcid.org/0000-0002-2012-8066"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Sonal Patel","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2012-8066","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5025845974"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"85","issue":"2","first_page":"40","last_page":"47"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.9667999744415283,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.9667999744415283,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11199","display_name":"Pain Management and Opioid Use","score":0.016699999570846558,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11840","display_name":"Pain Management and Treatment","score":0.012299999594688416,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuropathic-pain","display_name":"neuropathic pain","score":1.0},{"id":"https://openalex.org/keywords/pain-management","display_name":"pain management","score":0.652999997138977},{"id":"https://openalex.org/keywords/pregabalin","display_name":"pregabalin","score":0.9649999737739563},{"id":"https://openalex.org/keywords/gabapentin","display_name":"gabapentin","score":1.0},{"id":"https://openalex.org/keywords/tricyclic-antidepressants","display_name":"tricyclic antidepressants","score":0.9950000047683716},{"id":"https://openalex.org/keywords/serotonin-norepinephrine-reuptake-inhibitors","display_name":"serotonin-norepinephrine reuptake inhibitors","score":0.9559999704360962},{"id":"https://openalex.org/keywords/opioids","display_name":"opioids","score":0.8529999852180481},{"id":"https://openalex.org/keywords/melatonin","display_name":"melatonin","score":0.9190000295639038},{"id":"https://openalex.org/keywords/hyperalgesia","display_name":"hyperalgesia","score":0.8460000157356262},{"id":"https://openalex.org/keywords/hypaesthesia","display_name":"hypaesthesia","score":0.7319999933242798},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.5019999742507935},{"id":"https://openalex.org/keywords/hiv-infection","display_name":"HIV infection","score":0.824999988079071},{"id":"https://openalex.org/keywords/herpes-zoster","display_name":"herpes zoster","score":0.9620000123977661},{"id":"https://openalex.org/keywords/south-africa","display_name":"South Africa","score":0.46000000834465027}],"concepts":[{"id":"https://openalex.org/C2777107010","wikidata":"https://www.wikidata.org/wiki/Q2798704","display_name":"Neuropathic pain","level":2,"score":0.8853521347045898},{"id":"https://openalex.org/C2776468701","wikidata":"https://www.wikidata.org/wiki/Q412174","display_name":"Pregabalin","level":2,"score":0.8176407814025879},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8164576292037964},{"id":"https://openalex.org/C2776608144","wikidata":"https://www.wikidata.org/wiki/Q410352","display_name":"Gabapentin","level":3,"score":0.7343947291374207},{"id":"https://openalex.org/C55932262","wikidata":"https://www.wikidata.org/wiki/Q7827726","display_name":"Pain ladder","level":4,"score":0.6442629098892212},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.6124312281608582},{"id":"https://openalex.org/C2780764818","wikidata":"https://www.wikidata.org/wiki/Q411932","display_name":"Duloxetine","level":3,"score":0.45121482014656067},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.4503442645072937},{"id":"https://openalex.org/C2779245659","wikidata":"https://www.wikidata.org/wiki/Q1633866","display_name":"Hyperalgesia","level":4,"score":0.4475018084049225},{"id":"https://openalex.org/C15490471","wikidata":"https://www.wikidata.org/wiki/Q2734305","display_name":"Nociception","level":3,"score":0.3703334927558899},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3336208760738373},{"id":"https://openalex.org/C2781063702","wikidata":"https://www.wikidata.org/wiki/Q427523","display_name":"Opioid","level":3,"score":0.17007988691329956},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15264439582824707},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.09218469262123108},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2801569260","doi":null,"is_oa":false,"landing_page_url":"http://sapj.co.za/index.php/SAPJ/article/download/2558/5030","pdf_url":null,"source":{"id":"https://openalex.org/S4306530482","display_name":"South African Pharmaceutical Journal","issn_l":"0257-8719","issn":["0257-8719"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"South African Pharmaceutical Journal","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":4,"referenced_works":["https://openalex.org/W2092918915","https://openalex.org/W2138250439","https://openalex.org/W2166608133","https://openalex.org/W2268487502"],"related_works":["https://openalex.org/W2138250439","https://openalex.org/W2515617441","https://openalex.org/W2595568682","https://openalex.org/W2945221498","https://openalex.org/W2520200135","https://openalex.org/W2600033329","https://openalex.org/W2331586275","https://openalex.org/W2097688771","https://openalex.org/W4415660786","https://openalex.org/W117502898"],"abstract_inverted_index":{"Neuropathic":[0],"pain":[1,5,70,117,128],"is":[2,71,99],"defined":[3],"as":[4,44,74],"that":[6,160],"originates":[7],"due":[8],"to":[9,92,139,198],"a":[10,93,162,172,192],"lesion,":[11],"dysfunction":[12],"or":[13,22,29,54,56,60],"disease,":[14],"e.g.":[15],"diabetes,":[16],"HIV":[17],"infection,":[18],"herpes":[19],"zoster,":[20],"chemotherapy":[21],"surgery,":[23],"and":[24,81,84,87,101,137,149,154,200],"which":[25,48,96,197],"affects":[26],"the":[27,97,113,119,167],"peripheral":[28],"central":[30],"nervous":[31],"system.":[32],"This":[33],"results":[34],"in":[35,41,95,118,185],"abnormal":[36],"neural":[37],"function,":[38],"often":[39,72],"presenting":[40],"an":[42,106],"individual":[43],"sensory":[45],"pain-related":[46],"symptoms":[47,177],"are":[49],"either":[50],"positive,":[51],"i.e.":[52,58],"hyperaesthesia":[53],"hyperalgesia;":[55],"negative,":[57],"hypoaesthesia":[59],"anaesthesia.":[61],"The":[62,182],"quality":[63],"of":[64,66,115,132],"life":[65],"patients":[67],"with":[68,179,191,196],"neuropathic":[69,116,180,202],"compromised":[73],"many":[75],"have":[76,158],"difficulty":[77],"sleeping,":[78],"lack":[79],"energy,":[80],"experience":[82],"drowsiness":[83],"altered":[85],"concentration,":[86],"this":[88,186],"can":[89],"potentially":[90],"progress":[91],"stage":[94],"patient":[98],"physically":[100],"psychologically":[102],"distressed.":[103],"In":[104],"2012,":[105],"expert":[107],"panel":[108],"proposed":[109],"clinical":[110],"guidelines":[111,124,183],"for":[112,165,176],"treatment":[114],"South":[120],"African":[121],"context.":[122],"These":[123],"shifted":[125],"from":[126],"traditional":[127],"management,":[129],"primarily":[130],"comprised":[131],"nonsteroidal":[133],"anti-inflammatory":[134],"drugs":[135],"(NSAIDs)":[136],"opioids,":[138],"alternative":[140],"therapeutic":[141,174],"agents":[142],"including":[143],"pregabalin,":[144],"gabapentin,":[145],"tricyclic":[146],"antidepressants,":[147],"serotonin":[148],"noradrenaline":[150],"reuptake":[151],"inhibitors":[152],"(SNRIs)":[153],"opioids.":[155],"Recent":[156],"studies":[157],"suggested":[159],"melatonin,":[161],"neurohormone":[163],"responsible":[164],"regulating":[166],"circadian":[168],"rhythm,":[169],"may":[170],"be":[171],"potential":[173],"agent":[175],"associated":[178],"pain.":[181,203],"reviewed":[184],"article":[187],"offer":[188],"healthcare":[189],"providers":[190],"concise":[193],"step-wise":[194],"approach":[195],"diagnose":[199],"treat":[201]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-05-17T00:00:00"}