{"id":"https://openalex.org/W2801460957","doi":"https://doi.org/10.1093/sleep/zsy061.212","title":"0213 Trait-like Vulnerability Of Higher-order Cognition To Sleep Loss And Circadian Misalignment","display_name":"0213 Trait-like Vulnerability Of Higher-order Cognition To Sleep Loss And Circadian Misalignment","publication_year":2018,"publication_date":"2018-04-01","ids":{"openalex":"https://openalex.org/W2801460957","doi":"https://doi.org/10.1093/sleep/zsy061.212","mag":"2801460957"},"language":"en","primary_location":{"id":"doi:10.1093/sleep/zsy061.212","doi":"https://doi.org/10.1093/sleep/zsy061.212","is_oa":false,"landing_page_url":"https://doi.org/10.1093/sleep/zsy061.212","pdf_url":null,"source":{"id":"https://openalex.org/S42921845","display_name":"SLEEP","issn_l":"0161-8105","issn":["0161-8105","1550-9109"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sleep","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044295474","display_name":"Kate E. Sprecher","orcid":"https://orcid.org/0000-0002-7918-7108","observed_orcids":["https://orcid.org/0000-0002-7918-7108"]},"institutions":[{"id":"https://openalex.org/I188538660","display_name":"University of Colorado Boulder","ror":"https://ror.org/02ttsq026","country_code":"US","type":"education","lineage":["https://openalex.org/I188538660"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K E Sprecher","raw_affiliation_strings":["Sleep and Chronobiology Lab, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sleep and Chronobiology Lab, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO","institution_ids":["https://openalex.org/I188538660"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070008277","display_name":"HK Ritchie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I188538660","display_name":"University of Colorado Boulder","ror":"https://ror.org/02ttsq026","country_code":"US","type":"education","lineage":["https://openalex.org/I188538660"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H E Ritchie","raw_affiliation_strings":["Sleep and Chronobiology Lab, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sleep and Chronobiology Lab, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO","institution_ids":["https://openalex.org/I188538660"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106236011","display_name":"Tina M. Burke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I188538660","display_name":"University of Colorado Boulder","ror":"https://ror.org/02ttsq026","country_code":"US","type":"education","lineage":["https://openalex.org/I188538660"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T M Burke","raw_affiliation_strings":["Sleep and Chronobiology Lab, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sleep and Chronobiology Lab, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO","institution_ids":["https://openalex.org/I188538660"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027738794","display_name":"Christopher M. Depner","orcid":"https://orcid.org/0000-0003-2528-5455","observed_orcids":["https://orcid.org/0000-0003-2528-5455"]},"institutions":[{"id":"https://openalex.org/I188538660","display_name":"University of Colorado Boulder","ror":"https://ror.org/02ttsq026","country_code":"US","type":"education","lineage":["https://openalex.org/I188538660"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C M Depner","raw_affiliation_strings":["Sleep and Chronobiology Lab, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sleep and Chronobiology Lab, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO","institution_ids":["https://openalex.org/I188538660"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082720301","display_name":"Pieter C. Dorrestein","orcid":"https://orcid.org/0000-0002-3003-1030","observed_orcids":["https://orcid.org/0000-0002-3003-1030"]},"institutions":[{"id":"https://openalex.org/I2803209242","display_name":"University of California System","ror":"https://ror.org/00pjdza24","country_code":"US","type":"education","lineage":["https://openalex.org/I2803209242"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P C Dorrestein","raw_affiliation_strings":["Skaggs School of Pharmacy and Pharmaceutical Sciences, Center for Microbiome Innovation and Collaborative Mass Spectrometry Innovation Center, University of California, La Jolla, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Skaggs School of Pharmacy and Pharmaceutical Sciences, Center for Microbiome Innovation and Collaborative Mass Spectrometry Innovation Center, University of California, La Jolla, CA","institution_ids":["https://openalex.org/I2803209242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033720615","display_name":"Monika Fleshner","orcid":"https://orcid.org/0000-0002-0470-0827","observed_orcids":["https://orcid.org/0000-0002-0470-0827"]},"institutions":[{"id":"https://openalex.org/I188538660","display_name":"University of Colorado Boulder","ror":"https://ror.org/02ttsq026","country_code":"US","type":"education","lineage":["https://openalex.org/I188538660"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M Fleshner","raw_affiliation_strings":["Stress Physiology Laboratory, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stress Physiology Laboratory, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO","institution_ids":["https://openalex.org/I188538660"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033881627","display_name":"Rob D. Knight","orcid":"https://orcid.org/0000-0002-0975-9019","observed_orcids":["https://orcid.org/0000-0002-0975-9019","https://orcid.org/0000-0001-7531-0087"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R Knight","raw_affiliation_strings":["Departments of Pediatrics and Computer Science and Engineering and Center for Microbiome Innovation, University of California, San Diego CA, USA, La Jolla, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics and Computer Science and Engineering and Center for Microbiome Innovation, University of California, San Diego CA, USA, La Jolla, CA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020963967","display_name":"Christopher A. Lowry","orcid":"https://orcid.org/0000-0003-3920-5575","observed_orcids":["https://orcid.org/0000-0003-3920-5575"]},"institutions":[{"id":"https://openalex.org/I188538660","display_name":"University of Colorado Boulder","ror":"https://ror.org/02ttsq026","country_code":"US","type":"education","lineage":["https://openalex.org/I188538660"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C A Lowry","raw_affiliation_strings":["Behavioral Neuroendocrinology Laboratory, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Behavioral Neuroendocrinology Laboratory, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO","institution_ids":["https://openalex.org/I188538660"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084820716","display_name":"Fred William Turek","orcid":"https://orcid.org/0000-0002-4031-4229","observed_orcids":["https://orcid.org/0000-0002-4031-4229"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"F W Turek","raw_affiliation_strings":["Center for Sleep and Circadian Biology, Northwestern University, Evanston, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Sleep and Circadian Biology, Northwestern University, Evanston, IL","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003825512","display_name":"Martha Hotz Vitaterna","orcid":"https://orcid.org/0000-0001-6243-2093","observed_orcids":["https://orcid.org/0000-0001-6243-2093"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M H Vitaterna","raw_affiliation_strings":["Center for Sleep and Circadian Biology, Northwestern University, Evanston, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Sleep and Circadian Biology, Northwestern University, Evanston, IL","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004701207","display_name":"Kenneth P. Wright","orcid":"https://orcid.org/0000-0002-1781-7469","observed_orcids":["https://orcid.org/0000-0002-1781-7469"]},"institutions":[{"id":"https://openalex.org/I188538660","display_name":"University of Colorado Boulder","ror":"https://ror.org/02ttsq026","country_code":"US","type":"education","lineage":["https://openalex.org/I188538660"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K P Wright","raw_affiliation_strings":["Sleep and Chronobiology Lab, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sleep and Chronobiology Lab, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO","institution_ids":["https://openalex.org/I188538660"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4388,"currency":"USD","value_usd":4388},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.05084789,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"41","issue":"suppl_1","first_page":"A83","last_page":"A84"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11373","display_name":"Sleep and Work-Related Fatigue","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11373","display_name":"Sleep and Work-Related Fatigue","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sleep-restriction","display_name":"sleep restriction","score":0.9350000023841858},{"id":"https://openalex.org/keywords/circadian-misalignment","display_name":"circadian misalignment","score":0.9980000257492065},{"id":"https://openalex.org/keywords/higher-order-cognition","display_name":"higher-order cognition","score":0.7540000081062317},{"id":"https://openalex.org/keywords/executive-function","display_name":"executive function","score":0.7509999871253967},{"id":"https://openalex.org/keywords/processing-speed","display_name":"processing speed","score":0.8270000219345093},{"id":"https://openalex.org/keywords/selective-visual-attention","display_name":"visual selective attention","score":0.9580000042915344},{"id":"https://openalex.org/keywords/individual-differences","display_name":"individual differences","score":0.6700000166893005},{"id":"https://openalex.org/keywords/stroop-color-word-task","display_name":"Stroop color-word task","score":0.6620000004768372},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.5239999890327454}],"concepts":[{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.7312038540840149},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6657567620277405},{"id":"https://openalex.org/C121446783","wikidata":"https://www.wikidata.org/wiki/Q208353","display_name":"Circadian rhythm","level":2,"score":0.648063600063324},{"id":"https://openalex.org/C162967406","wikidata":"https://www.wikidata.org/wiki/Q384176","display_name":"Stroop effect","level":3,"score":0.6317130327224731},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.5800983905792236},{"id":"https://openalex.org/C2778329153","wikidata":"https://www.wikidata.org/wiki/Q1364801","display_name":"Sleep deprivation","level":3,"score":0.5536959171295166},{"id":"https://openalex.org/C185711340","wikidata":"https://www.wikidata.org/wiki/Q5347381","display_name":"Effects of sleep deprivation on cognitive performance","level":3,"score":0.5275898575782776},{"id":"https://openalex.org/C2780937657","wikidata":"https://www.wikidata.org/wiki/Q5141192","display_name":"Sleep restriction","level":4,"score":0.5083341002464294},{"id":"https://openalex.org/C102959455","wikidata":"https://www.wikidata.org/wiki/Q7313954","display_name":"Repeated measures design","level":2,"score":0.425638347864151},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.3412608504295349},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.17505693435668945},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1660510003566742},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.06838929653167725},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1093/sleep/zsy061.212","doi":"https://doi.org/10.1093/sleep/zsy061.212","is_oa":false,"landing_page_url":"https://doi.org/10.1093/sleep/zsy061.212","pdf_url":null,"source":{"id":"https://openalex.org/S42921845","display_name":"SLEEP","issn_l":"0161-8105","issn":["0161-8105","1550-9109"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sleep","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8048999905586243}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2944238437","https://openalex.org/W7071977799","https://openalex.org/W2609148778","https://openalex.org/W2939920978","https://openalex.org/W2803010011","https://openalex.org/W2014368744","https://openalex.org/W2912284734","https://openalex.org/W4410502257","https://openalex.org/W2096328158","https://openalex.org/W3094709543"],"abstract_inverted_index":{"The":[0,110],"degree":[1],"of":[2,84,170,257,291,303,319,329],"cognitive":[3,20,36,62,146,174,210,278],"impairment":[4],"induced":[5],"by":[6,81,178],"sleep":[7,27,53,88,97,115,205,250,267,283,305],"and":[8,28,55,58,65,127,132,145,157,195,197,207,222,229,247,252,269,284,293,306,315],"circadian":[9,29,56,208,253,270,285,307],"disruption":[10,30],"has":[11,287],"been":[12],"reported":[13],"to":[14,26,219,259,282],"be":[15],"trait-like":[16,264,274],"for":[17,34,41,99,107,216,289,296],"many":[18],"basic":[19],"domains.":[21],"Individual":[22],"differences":[23,172],"in":[24,104,173],"vulnerability":[25,281],"remain":[31],"largely":[32],"unexplored":[33],"higher-order":[35,277],"functions":[37],"that":[38],"are":[39],"critical":[40],"real-world":[42],"tasks.":[43],"This":[44],"study":[45],"simulated":[46],"repeated":[47,76],"continuous":[48],"operations":[49],"duty":[50],"schedules":[51],"combining":[52],"restriction":[54,206,251,268],"misalignment,":[57,209,254,308],"tested":[59,150,162],"executive":[60,225],"function,":[61],"processing":[63,147,211],"speed,":[64],"selective":[66,158,231],"visual":[67,159,166,230],"attention.":[68],"16":[69],"adults":[70],"(7":[71],"female)":[72],"aged":[73],"25.8":[74],"(\u00b14.5SD)":[75],"an":[77],"18-day":[78],"protocol,":[79],"separated":[80],"3":[82],"days":[83],"ad":[85],"libitum":[86],"recovery":[87],"at":[89,245],"home.":[90],"Participants":[91],"maintained":[92],"a":[93,152,164,192],"habitual":[94],"self-selected":[95],"8h":[96,119],"schedule":[98],"two":[100,126],"weeks":[101],"then":[102],"stayed":[103],"the":[105,310],"laboratory":[106,111],"four":[108],"days.":[109],"visit":[112,196],"included":[113],"one":[114],"opportunity":[116],"per":[117],"day:":[118],"on":[120,124,129,276],"night":[121,125],"one,":[122],"3h":[123,128,139],"mornings":[130],"three":[131],"four.":[133],"Cognitive":[134],"testing":[135],"was":[136,161,240],"performed":[137],"every":[138],"during":[140,248],"scheduled":[141],"wakefulness.":[142],"Executive":[143],"function":[144,175,226],"speed":[148,212],"were":[149,176,235],"with":[151,163,189,255],"Stroop":[153],"Color":[154],"Word":[155],"task":[156],"attention":[160,232],"conjunction":[165],"search":[167],"task.":[168],"Stability":[169],"individual":[171],"quantified":[177],"intra-class":[179],"correlation":[180],"coefficients":[181],"(ICC)":[182],"derived":[183],"from":[184],"linear":[185],"mixed":[186],"effects":[187,275],"models":[188],"subject":[190],"as":[191,200],"random":[193],"factor":[194],"battery":[198],"number":[199],"fixed":[201],"factors.":[202],"During":[203],"combined":[204,249],"(median":[213],"reaction":[214],"times":[215],"correct":[217],"responses":[218],"congruent,":[220],"neutral,":[221],"incongruent":[223],"stimuli),":[224],"(inhibitory":[227],"control),":[228],"(cognitive":[233],"throughput)":[234],"significantly":[236],"impaired":[237],"(p<.05).":[238],"Performance":[239],"highly":[241],"consistent":[242],"within":[243],"individuals":[244],"baseline":[246],"ICCs":[256],"0.86":[258],"0.93":[260],"indicating":[261],"\u201calmost":[262],"perfect\u201d":[263],"stability.":[265],"Combined":[266],"misalignment":[271],"produce":[272],"robust,":[273],"functions.":[279],"Consistent":[280],"disturbance":[286],"implications":[288],"development":[290],"individualized":[292],"targeted":[294],"countermeasures":[295],"workers":[297,314],"performing":[298],"safety-critical":[299],"tasks":[300],"under":[301],"conditions":[302],"insufficient":[304],"e.g.,":[309],"military,":[311],"health":[312],"care":[313],"emergency":[316],"responders.":[317],"Office":[318],"Naval":[320],"Research":[321,325],"MURI":[322],"N00014-15-1-2809;":[323],"Undergraduate":[324],"Opportunities":[326],"Grant,":[327],"University":[328],"Colorado":[330],"Boulder.":[331]},"counts_by_year":[],"updated_date":"2026-10-17T09:40:24.721904","created_date":"2018-05-17T00:00:00"}