{"id":"https://openalex.org/W2801335136","doi":"https://doi.org/10.21767/2472-1646.100044","title":"miRNAs Set Expression Profiles in Whole Blood During Prostate Cancer Patients Treatment","display_name":"miRNAs Set Expression Profiles in Whole Blood During Prostate Cancer Patients Treatment","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2801335136","doi":"https://doi.org/10.21767/2472-1646.100044","mag":"2801335136"},"language":"en","primary_location":{"id":"doi:10.21767/2472-1646.100044","doi":"https://doi.org/10.21767/2472-1646.100044","is_oa":true,"landing_page_url":"https://doi.org/10.21767/2472-1646.100044","pdf_url":"http://biomarkers.imedpub.com/mirnas-set-expression-profiles-in-wholeblood-during-prostate-cancer-patients-treatment.pdf","source":{"id":"https://openalex.org/S4210190027","display_name":"Biomarkers Journal","issn_l":"2472-1646","issn":["2472-1646"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomarkers Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://biomarkers.imedpub.com/mirnas-set-expression-profiles-in-wholeblood-during-prostate-cancer-patients-treatment.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036859870","display_name":"Katarzyna Monika Lamperska","orcid":"https://orcid.org/0000-0001-7583-207X","observed_orcids":["https://orcid.org/0000-0001-7583-207X"]},"institutions":[{"id":"https://openalex.org/I4210112614","display_name":"Greater Poland Cancer Center","ror":"https://ror.org/0243nmr44","country_code":"PL","type":"other","lineage":["https://openalex.org/I4210112614"]}],"countries":["PL"],"is_corresponding":true,"raw_author_name":"Katarzyna Monika Lamperska","raw_affiliation_strings":["Cancer Genetic Laboratory , Greater Poland Cancer Centre , Poznan , Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Genetic Laboratory , Greater Poland Cancer Centre , Poznan , Poland","institution_ids":["https://openalex.org/I4210112614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062635494","display_name":"Piotr Milecki","orcid":"https://orcid.org/0000-0002-2215-3695","observed_orcids":["https://orcid.org/0000-0002-2215-3695"]},"institutions":[{"id":"https://openalex.org/I120230055","display_name":"Poznan University of Medical Sciences","ror":"https://ror.org/02zbb2597","country_code":"PL","type":"education","lineage":["https://openalex.org/I120230055"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Piotr Milecki","raw_affiliation_strings":["Electro-radiology Department, University of Medical Sciences, Poznan, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Electro-radiology Department, University of Medical Sciences, Poznan, Poland","institution_ids":["https://openalex.org/I120230055"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071937365","display_name":"Tomasz Kolenda","orcid":"https://orcid.org/0000-0001-5623-7398","observed_orcids":["https://orcid.org/0000-0001-5623-7398"]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]},{"id":"https://openalex.org/I4210112614","display_name":"Greater Poland Cancer Center","ror":"https://ror.org/0243nmr44","country_code":"PL","type":"other","lineage":["https://openalex.org/I4210112614"]},{"id":"https://openalex.org/I4210134719","display_name":"Postgraduate School of Molecular Medicine","ror":"https://ror.org/03jgmfc14","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210134719"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Tomasz Kolenda","raw_affiliation_strings":["Cancer Genetic Laboratory, Greater Poland Cancer Centre, Poznan, Poland","Postgraduate School of Molecular Medicine, Medical University of Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Genetic Laboratory, Greater Poland Cancer Centre, Poznan, Poland","institution_ids":["https://openalex.org/I4210112614"]},{"raw_affiliation_string":"Postgraduate School of Molecular Medicine, Medical University of Warsaw, Poland","institution_ids":["https://openalex.org/I268303160","https://openalex.org/I4210134719"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011901659","display_name":"Anna Teresiak","orcid":"https://orcid.org/0000-0002-5327-6698","observed_orcids":["https://orcid.org/0000-0002-5327-6698"]},"institutions":[{"id":"https://openalex.org/I4210112614","display_name":"Greater Poland Cancer Center","ror":"https://ror.org/0243nmr44","country_code":"PL","type":"other","lineage":["https://openalex.org/I4210112614"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Anna Teresiak","raw_affiliation_strings":["Cancer Genetic Laboratory, Greater Poland Cancer Centre, Poznan, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Genetic Laboratory, Greater Poland Cancer Centre, Poznan, Poland","institution_ids":["https://openalex.org/I4210112614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041738551","display_name":"Renata Bli\u017aniak","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210112614","display_name":"Greater Poland Cancer Center","ror":"https://ror.org/0243nmr44","country_code":"PL","type":"other","lineage":["https://openalex.org/I4210112614"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Renata Blizniak","raw_affiliation_strings":["Cancer Genetic Laboratory, Greater Poland Cancer Centre, Poznan, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Genetic Laboratory, Greater Poland Cancer Centre, Poznan, Poland","institution_ids":["https://openalex.org/I4210112614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103739891","display_name":"Aldona Kaczmarek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210112614","display_name":"Greater Poland Cancer Center","ror":"https://ror.org/0243nmr44","country_code":"PL","type":"other","lineage":["https://openalex.org/I4210112614"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Aldona Kaczmarek","raw_affiliation_strings":["Department of Pathology, Greater Poland Cancer Centre, Poznan, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Greater Poland Cancer Centre, Poznan, Poland","institution_ids":["https://openalex.org/I4210112614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002711498","display_name":"Ewa Leporowska","orcid":"https://orcid.org/0000-0001-5193-8697","observed_orcids":["https://orcid.org/0000-0001-5193-8697"]},"institutions":[{"id":"https://openalex.org/I4210112614","display_name":"Greater Poland Cancer Center","ror":"https://ror.org/0243nmr44","country_code":"PL","type":"other","lineage":["https://openalex.org/I4210112614"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Ewa Leporowska","raw_affiliation_strings":["Department of Clinical Laboratory, Greater Poland Cancer Centre, Poznan, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Laboratory, Greater Poland Cancer Centre, Poznan, Poland","institution_ids":["https://openalex.org/I4210112614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020265542","display_name":"Wiktoria Maria Suchorska","orcid":"https://orcid.org/0000-0003-4742-2465","observed_orcids":["https://orcid.org/0000-0003-4742-2465"]},"institutions":[{"id":"https://openalex.org/I120230055","display_name":"Poznan University of Medical Sciences","ror":"https://ror.org/02zbb2597","country_code":"PL","type":"education","lineage":["https://openalex.org/I120230055"]},{"id":"https://openalex.org/I4210112614","display_name":"Greater Poland Cancer Center","ror":"https://ror.org/0243nmr44","country_code":"PL","type":"other","lineage":["https://openalex.org/I4210112614"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Wiktoria Suchorska","raw_affiliation_strings":["Medical Physics and Electro-radiology Department, Greater Poland Cancer Centre, University of Medical Sciences, Poznan, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Physics and Electro-radiology Department, Greater Poland Cancer Centre, University of Medical Sciences, Poznan, Poland","institution_ids":["https://openalex.org/I120230055","https://openalex.org/I4210112614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016480418","display_name":"Julian Malicki","orcid":"https://orcid.org/0000-0002-5558-5558","observed_orcids":["https://orcid.org/0000-0002-5558-5558"]},"institutions":[{"id":"https://openalex.org/I120230055","display_name":"Poznan University of Medical Sciences","ror":"https://ror.org/02zbb2597","country_code":"PL","type":"education","lineage":["https://openalex.org/I120230055"]},{"id":"https://openalex.org/I4210112614","display_name":"Greater Poland Cancer Center","ror":"https://ror.org/0243nmr44","country_code":"PL","type":"other","lineage":["https://openalex.org/I4210112614"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Julian Malicki","raw_affiliation_strings":["Medical Physics and Electro-radiology Department, Greater Poland Cancer Centre, University of Medical Sciences, Poznan, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Physics and Electro-radiology Department, Greater Poland Cancer Centre, University of Medical Sciences, Poznan, Poland","institution_ids":["https://openalex.org/I120230055","https://openalex.org/I4210112614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069060836","display_name":"Agata Jurczyk Reszelska","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210112614","display_name":"Greater Poland Cancer Center","ror":"https://ror.org/0243nmr44","country_code":"PL","type":"other","lineage":["https://openalex.org/I4210112614"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Agata Jurczyk Reszelska","raw_affiliation_strings":["Cancer Genetic Laboratory, Greater Poland Cancer Centre, Poznan, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Genetic Laboratory, Greater Poland Cancer Centre, Poznan, Poland","institution_ids":["https://openalex.org/I4210112614"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044113515","display_name":"Micha\u0142 Michalak","orcid":"https://orcid.org/0000-0002-2852-3984","observed_orcids":["https://orcid.org/0000-0002-2852-3984"]},"institutions":[{"id":"https://openalex.org/I120230055","display_name":"Poznan University of Medical Sciences","ror":"https://ror.org/02zbb2597","country_code":"PL","type":"education","lineage":["https://openalex.org/I120230055"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Michal Michalak","raw_affiliation_strings":["Department of Computer Science and Statistics, University of Medical Sciences, Poznan, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Statistics, University of Medical Sciences, Poznan, Poland","institution_ids":["https://openalex.org/I120230055"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5036859870"],"corresponding_institution_ids":["https://openalex.org/I4210112614"],"apc_list":null,"apc_paid":null,"fwci":0.0753,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.34099635,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"04","issue":"01","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.008899999782443047,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.9200000166893005},{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.9279999732971191},{"id":"https://openalex.org/keywords/whole-blood","display_name":"whole blood","score":0.7200000286102295},{"id":"https://openalex.org/keywords/mir-21","display_name":"miR-21","score":0.9490000009536743},{"id":"https://openalex.org/keywords/mir-100","display_name":"miR-100","score":1.0},{"id":"https://openalex.org/keywords/hormone-therapy","display_name":"hormone therapy","score":0.6570000052452087},{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.9990000128746033},{"id":"https://openalex.org/keywords/treatment-monitoring","display_name":"treatment monitoring","score":0.8399999737739563},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.8240000009536743},{"id":"https://openalex.org/keywords/microrna-expression-profiles","display_name":"microRNA expression profiles","score":0.6309999823570251}],"concepts":[{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.8793713450431824},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.7688589692115784},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7125266790390015},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.6696984171867371},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5795960426330566},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.5320532917976379},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5307348370552063},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4726730287075043},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.3315746784210205},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1143980324268341},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.06209304928779602},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.21767/2472-1646.100044","doi":"https://doi.org/10.21767/2472-1646.100044","is_oa":true,"landing_page_url":"https://doi.org/10.21767/2472-1646.100044","pdf_url":"http://biomarkers.imedpub.com/mirnas-set-expression-profiles-in-wholeblood-during-prostate-cancer-patients-treatment.pdf","source":{"id":"https://openalex.org/S4210190027","display_name":"Biomarkers Journal","issn_l":"2472-1646","issn":["2472-1646"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomarkers Journal","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.21767/2472-1646.100044","doi":"https://doi.org/10.21767/2472-1646.100044","is_oa":true,"landing_page_url":"https://doi.org/10.21767/2472-1646.100044","pdf_url":"http://biomarkers.imedpub.com/mirnas-set-expression-profiles-in-wholeblood-during-prostate-cancer-patients-treatment.pdf","source":{"id":"https://openalex.org/S4210190027","display_name":"Biomarkers Journal","issn_l":"2472-1646","issn":["2472-1646"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomarkers Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2801335136.pdf","grobid_xml":"https://content.openalex.org/works/W2801335136.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W1842148282","https://openalex.org/W1867260472","https://openalex.org/W1964453634","https://openalex.org/W1966101011","https://openalex.org/W1977135648","https://openalex.org/W1991034124","https://openalex.org/W1993908286","https://openalex.org/W2033479946","https://openalex.org/W2036446168","https://openalex.org/W2044512288","https://openalex.org/W2050822362","https://openalex.org/W2070297079","https://openalex.org/W2070412447","https://openalex.org/W2071813506","https://openalex.org/W2074689365","https://openalex.org/W2081735304","https://openalex.org/W2096528675","https://openalex.org/W2096619957","https://openalex.org/W2104287165","https://openalex.org/W2115093090","https://openalex.org/W2116100742","https://openalex.org/W2123128328","https://openalex.org/W2129253021","https://openalex.org/W2135731415","https://openalex.org/W2159219840","https://openalex.org/W2171974079","https://openalex.org/W2224829538","https://openalex.org/W2266501231","https://openalex.org/W2470595324","https://openalex.org/W2532590765","https://openalex.org/W2743518443"],"related_works":["https://openalex.org/W3208606855","https://openalex.org/W2904168711","https://openalex.org/W2968161868","https://openalex.org/W4393071873","https://openalex.org/W2196499313","https://openalex.org/W2890059315","https://openalex.org/W4391303613","https://openalex.org/W962343021","https://openalex.org/W2040298154","https://openalex.org/W3049626404"],"abstract_inverted_index":{"Background:":[0],"Changes":[1],"in":[2,12,97,108,118,182],"expression":[3,27,99,151,169],"profiles":[4,28],"of":[5,15,29,61,111,143,193],"the":[6,26,30,90,93,98,109,114,119,126,132,141,147,165,175,191],"5":[7],"selected":[8],"miRNAs":[9,31,78,180],"were":[10,79,101,153,159],"analysed":[11,80],"a":[13],"group":[14,59,110,128,136,170],"PC":[16,63],"patients":[17,52,112],"before":[18,71],"treatment,":[19,72],"after":[20,73,103],"hormonotherapy":[21,74],"and":[22,53,75,123,130,149,167],"radiotherapy.":[23,76],"Objective:":[24],"Whether":[25],"may":[32],"be":[33],"useful":[34],"for":[35,66,105,125,131,190,195],"monitoring":[36],"prostate":[37,50,196],"cancer":[38,51,197],"treatment.":[39,162],"Methods:":[40],"The":[41,57,77,138,156,179],"initial":[42],"study":[43,121],"was":[44,69],"carried":[45],"out":[46],"on":[47],"44":[48],"advanced":[49],"41":[54],"healthy":[55],"volunteers.":[56],"target":[58,91],"consisted":[60],"39":[62],"patients.":[64,198],"Blood":[65],"miRNA":[67,145],"analysis":[68],"taken":[70],"by":[81,85],"real-time":[82],"PCR,":[83],"followed":[84],"statistical":[86],"analysis.":[87],"Results:":[88],"For":[89],"group,":[92],"statistically":[94,154],"significant":[95],"differences":[96,139],"level":[100],"found":[102],"radiotherapy:":[104],"miR-21":[106],"only":[107],"above":[113,133],"cut-off":[115,134],"value":[116,135],"designed":[117,157],"preliminary":[120],"(p=0.0369)":[122],"miR-100":[124],"whole":[127],"(p=0.0413)":[129],"(p=0.0140).":[137],"between":[140,146],"levels":[142,171],"each":[144],"high":[148,166],"low":[150,168],"groups":[152,158],"significant.":[155],"stable":[160],"during":[161],"Inclusion":[163],"to":[164],"did":[172],"not":[173,186],"influence":[174],"treatment":[176],"result.":[177],"Conclusion:":[178],"studied":[181],"this":[183],"work":[184],"could":[185],"serve":[187],"as":[188],"biomarkers":[189],"effectiveness":[192],"therapy":[194]},"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2018-05-17T00:00:00"}