{"id":"https://openalex.org/W2800285152","doi":"https://doi.org/10.3389/fneur.2018.00238","title":"Periprocedural Antithrombotic Treatment During Acute Mechanical Thrombectomy for Ischemic Stroke: A Systematic Review","display_name":"Periprocedural Antithrombotic Treatment During Acute Mechanical Thrombectomy for Ischemic Stroke: A Systematic Review","publication_year":2018,"publication_date":"2018-04-16","ids":{"openalex":"https://openalex.org/W2800285152","doi":"https://doi.org/10.3389/fneur.2018.00238","mag":"2800285152","pmid":"https://pubmed.ncbi.nlm.nih.gov/29713305","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5911634"},"language":"en","primary_location":{"id":"doi:10.3389/fneur.2018.00238","doi":"https://doi.org/10.3389/fneur.2018.00238","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fneur.2018.00238","pdf_url":"https://www.frontiersin.org/articles/10.3389/fneur.2018.00238/pdf","source":{"id":"https://openalex.org/S96975567","display_name":"Frontiers in Neurology","issn_l":"1664-2295","issn":["1664-2295"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neurology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fneur.2018.00238/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030705633","display_name":"Rob A. van de Graaf","orcid":"https://orcid.org/0000-0003-4459-0068","observed_orcids":["https://orcid.org/0000-0003-4459-0068"]},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Rob A. van de Graaf","raw_affiliation_strings":["Department of Neurology, Erasmus MC University Medical Center, Rotterdam, Netherlands","Department of Radiology, Erasmus MC University Medical Center, Rotterdam, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Erasmus MC University Medical Center, Rotterdam, Netherlands","institution_ids":["https://openalex.org/I2801952686"]},{"raw_affiliation_string":"Department of Radiology, Erasmus MC University Medical Center, Rotterdam, Netherlands","institution_ids":["https://openalex.org/I2801952686"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079930755","display_name":"Vicky Chalos","orcid":"https://orcid.org/0000-0003-4121-3865","observed_orcids":["https://orcid.org/0000-0003-4121-3865"]},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Vicky Chalos","raw_affiliation_strings":["Department of Neurology, Erasmus MC University Medical Center, Rotterdam, Netherlands","Department of Public Health, Erasmus MC University Medical Center, Rotterdam, Netherlands","Department of Radiology, Erasmus MC University Medical Center, Rotterdam, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Erasmus MC University Medical Center, Rotterdam, Netherlands","institution_ids":["https://openalex.org/I2801952686"]},{"raw_affiliation_string":"Department of Public Health, Erasmus MC University Medical Center, Rotterdam, Netherlands","institution_ids":["https://openalex.org/I2801952686"]},{"raw_affiliation_string":"Department of Radiology, Erasmus MC University Medical Center, Rotterdam, Netherlands","institution_ids":["https://openalex.org/I2801952686"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111736311","display_name":"Gregory J. del Zoppo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gregory J. del Zoppo","raw_affiliation_strings":["Department of Neurology, University of Washington School of Medicine, Seattle, WA, United States","Division of Hematology, Department of Medicine, University of Washington School of Medicine, Seattle, WA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of Washington School of Medicine, Seattle, WA, United States","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Division of Hematology, Department of Medicine, University of Washington School of Medicine, Seattle, WA, United States","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006225939","display_name":"Aad van der Lugt","orcid":"https://orcid.org/0000-0002-6159-2228","observed_orcids":["https://orcid.org/0000-0002-6159-2228"]},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Aad van der Lugt","raw_affiliation_strings":["Department of Radiology, Erasmus MC University Medical Center, Rotterdam, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Erasmus MC University Medical Center, Rotterdam, Netherlands","institution_ids":["https://openalex.org/I2801952686"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048297907","display_name":"Diederik W.J. Dippel","orcid":"https://orcid.org/0000-0002-9234-3515","observed_orcids":["https://orcid.org/0000-0002-9234-3515"]},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Diederik W. J. Dippel","raw_affiliation_strings":["Department of Neurology, Erasmus MC University Medical Center, Rotterdam, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Erasmus MC University Medical Center, Rotterdam, Netherlands","institution_ids":["https://openalex.org/I2801952686"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084860153","display_name":"Bob Roozenbeek","orcid":"https://orcid.org/0000-0002-8320-8303","observed_orcids":["https://orcid.org/0000-0002-8320-8303"]},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Bob Roozenbeek","raw_affiliation_strings":["Department of Neurology, Erasmus MC University Medical Center, Rotterdam, Netherlands","Department of Radiology, Erasmus MC University Medical Center, Rotterdam, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Erasmus MC University Medical Center, Rotterdam, Netherlands","institution_ids":["https://openalex.org/I2801952686"]},{"raw_affiliation_string":"Department of Radiology, Erasmus MC University Medical Center, Rotterdam, Netherlands","institution_ids":["https://openalex.org/I2801952686"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5030705633"],"corresponding_institution_ids":["https://openalex.org/I2801952686"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.9963,"has_fulltext":true,"cited_by_count":48,"citation_normalized_percentile":{"value":0.70682019,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"9","issue":null,"first_page":"238","last_page":"238"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10420","display_name":"Intracranial Aneurysms: Treatment and Complications","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11763","display_name":"Intracerebral and Subarachnoid Hemorrhage Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ischemic-stroke","display_name":"ischemic stroke","score":0.9789999723434448},{"id":"https://openalex.org/keywords/intracranial-large-vessel-occlusion","display_name":"intracranial large vessel occlusion","score":0.9440000057220459},{"id":"https://openalex.org/keywords/antiplatelet-drugs","display_name":"antiplatelet agents","score":0.9940000176429749},{"id":"https://openalex.org/keywords/heparin","display_name":"heparin","score":0.9869999885559082},{"id":"https://openalex.org/keywords/symptomatic-intracranial-hemorrhage","display_name":"symptomatic intracranial hemorrhage","score":0.996999979019165},{"id":"https://openalex.org/keywords/functional-outcome","display_name":"functional outcome","score":0.7919999957084656},{"id":"https://openalex.org/keywords/modified-rankin-scale","display_name":"modified Rankin Scale","score":0.9120000004768372},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.6240000128746033}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9104753732681274},{"id":"https://openalex.org/C2780931571","wikidata":"https://www.wikidata.org/wiki/Q568775","display_name":"Modified Rankin Scale","level":4,"score":0.8205520510673523},{"id":"https://openalex.org/C2777015399","wikidata":"https://www.wikidata.org/wiki/Q4775337","display_name":"Antithrombotic","level":2,"score":0.7504338026046753},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.572913408279419},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5252318382263184},{"id":"https://openalex.org/C2777557582","wikidata":"https://www.wikidata.org/wiki/Q190016","display_name":"Heparin","level":2,"score":0.523108720779419},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3970310091972351},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3316226601600647},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.3070545792579651},{"id":"https://openalex.org/C3020199598","wikidata":"https://www.wikidata.org/wiki/Q12202","display_name":"Ischemic stroke","level":3,"score":0.24999400973320007},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[],"locations_count":10,"locations":[{"id":"doi:10.3389/fneur.2018.00238","doi":"https://doi.org/10.3389/fneur.2018.00238","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fneur.2018.00238","pdf_url":"https://www.frontiersin.org/articles/10.3389/fneur.2018.00238/pdf","source":{"id":"https://openalex.org/S96975567","display_name":"Frontiers in Neurology","issn_l":"1664-2295","issn":["1664-2295"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neurology","raw_type":"journal-article"},{"id":"doi:10.26226/morressier.5ab8f565d462b8029238d720","doi":"https://doi.org/10.26226/morressier.5ab8f565d462b8029238d720","is_oa":false,"landing_page_url":"https://doi.org/10.26226/morressier.5ab8f565d462b8029238d720","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},{"id":"pmh:oai:europepmc.org:4848671","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5911634","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5911634","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5911634","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Neurol","raw_type":"Text"},{"id":"pmid:29713305","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29713305","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in neurology","raw_type":"Journal Article"},{"id":"pmh:oai:pure.eur.nl:openaire/f4eb3b3a-19d7-4ec0-aacc-9c769fa364c4","doi":null,"is_oa":true,"landing_page_url":"https://pure.eur.nl/en/publications/f4eb3b3a-19d7-4ec0-aacc-9c769fa364c4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"van de Graaf, R, Chalos - Andreou, V, del Zoppo, GJ, van der Lugt, A, Dippel, D & Roozenbeek, B 2018, 'Periprocedural Antithrombotic Treatment During Acute Mechanical Thrombectomy for Ischemic Stroke: A Systematic Review', Frontiers in Neurology, vol. 9, 238. https://doi.org/10.3389/fneur.2018.00238","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:eur:oai:pure.eur.nl:publications/f4eb3b3a-19d7-4ec0-aacc-9c769fa364c4","doi":null,"is_oa":true,"landing_page_url":"https://pure.eur.nl/en/publications/f4eb3b3a-19d7-4ec0-aacc-9c769fa364c4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Neurology, 9:238. Frontiers Media S.A.","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:eur:oai:repub.eur.nl:105902","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1765/105902","pdf_url":null,"source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Neurology, 9(APR)","raw_type":"info:eu-repo/semantics/other"},{"id":"pmh:oai:doaj.org/article:481b29f9be1744c3b1b751654ffac5ea","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/481b29f9be1744c3b1b751654ffac5ea","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Neurology, Vol 9 (2018)","raw_type":"article"},{"id":"pmh:oai:repub.eur.nl:105902","doi":null,"is_oa":true,"landing_page_url":"http://repub.eur.nl/pub/105902","pdf_url":null,"source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Neurology vol. 9 no. APR","raw_type":"info:eu-repo/semantics/other"}],"best_oa_location":{"id":"doi:10.3389/fneur.2018.00238","doi":"https://doi.org/10.3389/fneur.2018.00238","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fneur.2018.00238","pdf_url":"https://www.frontiersin.org/articles/10.3389/fneur.2018.00238/pdf","source":{"id":"https://openalex.org/S96975567","display_name":"Frontiers in Neurology","issn_l":"1664-2295","issn":["1664-2295"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neurology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"}],"awards":[{"id":"https://openalex.org/G7887457716","display_name":"Endothelial Beta 1-integrins in Cerebral Vascular Barrier Integrity","funder_award_id":"R01NS113393","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2800285152.pdf","grobid_xml":"https://content.openalex.org/works/W2800285152.grobid-xml"},"referenced_works_count":55,"referenced_works":["https://openalex.org/W205495280","https://openalex.org/W246286872","https://openalex.org/W1498265361","https://openalex.org/W1503609683","https://openalex.org/W1965593262","https://openalex.org/W1969661146","https://openalex.org/W1976425448","https://openalex.org/W1980369396","https://openalex.org/W1983998528","https://openalex.org/W1992145204","https://openalex.org/W1993355968","https://openalex.org/W1996802760","https://openalex.org/W2014796100","https://openalex.org/W2026458612","https://openalex.org/W2045819100","https://openalex.org/W2048670653","https://openalex.org/W2051824928","https://openalex.org/W2058046969","https://openalex.org/W2059494930","https://openalex.org/W2067436359","https://openalex.org/W2076147379","https://openalex.org/W2080504768","https://openalex.org/W2098032054","https://openalex.org/W2099706007","https://openalex.org/W2102447759","https://openalex.org/W2107889577","https://openalex.org/W2128872418","https://openalex.org/W2136587148","https://openalex.org/W2146307187","https://openalex.org/W2148303417","https://openalex.org/W2153792869","https://openalex.org/W2156098321","https://openalex.org/W2159233098","https://openalex.org/W2161272496","https://openalex.org/W2164763924","https://openalex.org/W2171173981","https://openalex.org/W2198398064","https://openalex.org/W2273024126","https://openalex.org/W2274451292","https://openalex.org/W2277258071","https://openalex.org/W2283435312","https://openalex.org/W2292308933","https://openalex.org/W2311452626","https://openalex.org/W2469502808","https://openalex.org/W2509299184","https://openalex.org/W2547704365","https://openalex.org/W2550364274","https://openalex.org/W2574716662","https://openalex.org/W2578681521","https://openalex.org/W2594440831","https://openalex.org/W2600151310","https://openalex.org/W2736038609","https://openalex.org/W2765874574","https://openalex.org/W2776578159","https://openalex.org/W4294215472"],"related_works":["https://openalex.org/W4409237389","https://openalex.org/W7140193128","https://openalex.org/W4402629990","https://openalex.org/W4376620491","https://openalex.org/W7126082777","https://openalex.org/W2926247356","https://openalex.org/W4416921574","https://openalex.org/W7160450765","https://openalex.org/W2151046062","https://openalex.org/W4378639360"],"abstract_inverted_index":{"BACKGROUND:":[0],"More":[1],"than":[2],"one-third":[3],"of":[4,63,70,82,103,148,157,161,176,182,185,193,228,241,259,306],"the":[5,61,76,98,119,146,158,183,257,299,302],"patients":[6,196],"with":[7,198],"ischemic":[8,92,113],"stroke":[9],"caused":[10],"by":[11,28,38,311],"an":[12,190],"intracranial":[13,65],"large":[14],"vessel":[15],"occlusion":[16],"do":[17],"not":[18],"recover":[19],"to":[20,52,74,166,173,206,212,248,297],"functional":[21,80,101,126,201,231,244,289,313],"independence":[22,127,202,232,245],"despite":[23],"fast":[24],"and":[25,47,79,100,135,168,208,220],"successful":[26],"recanalization":[27],"acute":[29,89,110],"mechanical":[30],"thrombectomy":[31],"(MT).":[32],"This":[33],"may":[34,49,58,278],"partially":[35],"be":[36,50,279,309],"explained":[37],"incomplete":[39],"microvascular":[40,54],"reperfusion.":[41,55],"Some":[42,267],"antithrombotics,":[43],"e.g.,":[44],"antiplatelet":[45,84,105,199],"agents":[46],"heparin,":[48,215],"able":[51],"restore":[53],"However,":[56],"antithrombotics":[57,186],"also":[59,283],"increase":[60,249,273],"risk":[62,120,192,305],"symptomatic":[64],"hemorrhage":[66],"(sICH).":[67],"The":[68,115,154,222],"aim":[69],"this":[71,216,250],"review":[72],"was":[73,118],"assess":[75],"potential":[77],"safety":[78,99],"outcome":[81,102,117],"periprocedural":[83,104,159,260],"or":[85,106],"heparin":[86,107,170,242],"use":[87,160,184],"during":[88,109],"MT":[90,111,264],"for":[91,95,112,121,169],"stroke.":[93,114],"METHODS:":[94],"studies":[96,142,151,178,224,237,269],"investigating":[97,256],"treatment":[108,262],"primary":[116],"sICH.":[122,194],"Secondary":[123],"outcomes":[124],"were":[125,143,152],"after":[128],"3-6":[129],"months":[130],"(modified":[131],"Rankin":[132],"Scale":[133],"0-2)":[134],"mortality":[136,209],"within":[137],"6":[138,165],"months.":[139],"RESULTS:":[140],"837":[141],"identified":[144],"through":[145],"search,":[147],"which":[149,277],"19":[150],"included.":[153],"sICH":[155,275,307],"risks":[156],"antiplatelets":[162,229],"ranged":[163],"from":[164,171,204,210],"17%,":[167],"5":[172],"12%.":[174],"Two":[175],"four":[177],"reporting":[179,238],"relative":[180,226,239],"effects":[181,227,240],"are":[187,265,295],"pointing":[188],"toward":[189],"increased":[191],"Among":[195],"treated":[197],"agents,":[200],"varied":[203],"23":[205],"60%":[207],"18":[211],"33%.":[213],"For":[214],"was,":[217],"respectively,":[218],"19-54%":[219],"19-33%.":[221],"three":[223],"presenting":[225],"on":[230,243,288],"showed":[233],"neutral":[234],"effects.":[235],"Both":[236],"found":[246],"it":[247],"chance.":[251],"CONCLUSION:":[252],"Randomized":[253],"controlled":[254,293],"trials":[255,294],"effect":[258,287],"antithrombotic":[261],"in":[263,274],"lacking.":[266],"observational":[268],"report":[270],"a":[271,285],"slight":[272],"risk,":[276],"acceptable":[280],"because":[281],"they":[282],"suggest":[284],"beneficial":[286],"outcome.":[290,314],"Therefore,":[291],"randomized":[292],"warranted":[296],"address":[298],"question":[300],"whether":[301],"potentially":[303],"higher":[304],"could":[308],"outweighed":[310],"improved":[312]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":13},{"year":2019,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-05-17T00:00:00"}