{"id":"https://openalex.org/W2799367128","doi":"https://doi.org/10.1089/aid.2017.0217","title":"HIV-1-Induced miR-146a Attenuates Monocyte Migration by Targeting CCL5 in Human Primary Macrophages","display_name":"HIV-1-Induced miR-146a Attenuates Monocyte Migration by Targeting CCL5 in Human Primary Macrophages","publication_year":2018,"publication_date":"2018-05-02","ids":{"openalex":"https://openalex.org/W2799367128","doi":"https://doi.org/10.1089/aid.2017.0217","mag":"2799367128","pmid":"https://pubmed.ncbi.nlm.nih.gov/29717615"},"language":"en","primary_location":{"id":"doi:10.1089/aid.2017.0217","doi":"https://doi.org/10.1089/aid.2017.0217","is_oa":false,"landing_page_url":"https://doi.org/10.1089/aid.2017.0217","pdf_url":null,"source":{"id":"https://openalex.org/S161282271","display_name":"AIDS Research and Human Retroviruses","issn_l":"0889-2229","issn":["0889-2229","1931-8405"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS Research and Human Retroviruses","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110370998","display_name":"Qiuling Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]},{"id":"https://openalex.org/I4391768268","display_name":"State Key Laboratory of Virology","ror":"https://ror.org/05sqd2v93","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I37461747","https://openalex.org/I4210106882","https://openalex.org/I4391768268"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiuling Huang","raw_affiliation_strings":["State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China","institution_ids":["https://openalex.org/I37461747","https://openalex.org/I4391768268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100450007","display_name":"Lang Chen","orcid":"https://orcid.org/0000-0003-3563-601X","observed_orcids":["https://orcid.org/0000-0003-3563-601X"]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]},{"id":"https://openalex.org/I4391768268","display_name":"State Key Laboratory of Virology","ror":"https://ror.org/05sqd2v93","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I37461747","https://openalex.org/I4210106882","https://openalex.org/I4391768268"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lang Chen","raw_affiliation_strings":["State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China","institution_ids":["https://openalex.org/I37461747","https://openalex.org/I4391768268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023835147","display_name":"Mingqi Luo","orcid":"https://orcid.org/0000-0001-8677-766X","observed_orcids":["https://orcid.org/0000-0001-8677-766X"]},"institutions":[{"id":"https://openalex.org/I4210120234","display_name":"Zhongnan Hospital of Wuhan University","ror":"https://ror.org/01v5mqw79","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210120234"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mingqi Luo","raw_affiliation_strings":["Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China","institution_ids":["https://openalex.org/I4210120234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113126434","display_name":"Hanlin Lv","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210140357","display_name":"Renmin Hospital of Wuhan University","ror":"https://ror.org/03ekhbz91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210140357"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hanlin Lv","raw_affiliation_strings":["Renmin Hospital of Wuhan University, Wuhan, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Renmin Hospital of Wuhan University, Wuhan, People's Republic of China","institution_ids":["https://openalex.org/I4210140357"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044832182","display_name":"Da Luo","orcid":"https://orcid.org/0000-0002-0179-6747","observed_orcids":["https://orcid.org/0000-0002-0179-6747"]},"institutions":[{"id":"https://openalex.org/I4210140357","display_name":"Renmin Hospital of Wuhan University","ror":"https://ror.org/03ekhbz91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210140357"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Da Luo","raw_affiliation_strings":["Renmin Hospital of Wuhan University, Wuhan, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Renmin Hospital of Wuhan University, Wuhan, People's Republic of China","institution_ids":["https://openalex.org/I4210140357"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100775809","display_name":"Li Tian","orcid":"https://orcid.org/0000-0003-0222-7076","observed_orcids":["https://orcid.org/0000-0003-0222-7076"]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]},{"id":"https://openalex.org/I4391768268","display_name":"State Key Laboratory of Virology","ror":"https://ror.org/05sqd2v93","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I37461747","https://openalex.org/I4210106882","https://openalex.org/I4391768268"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tian Li","raw_affiliation_strings":["State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China","institution_ids":["https://openalex.org/I37461747","https://openalex.org/I4391768268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046901575","display_name":"Szuyuan Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]},{"id":"https://openalex.org/I4391768268","display_name":"State Key Laboratory of Virology","ror":"https://ror.org/05sqd2v93","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I37461747","https://openalex.org/I4210106882","https://openalex.org/I4391768268"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Szuyuan Huang","raw_affiliation_strings":["State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China","institution_ids":["https://openalex.org/I37461747","https://openalex.org/I4391768268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035430754","display_name":"Linlin Xie","orcid":"https://orcid.org/0000-0001-5440-7701","observed_orcids":["https://orcid.org/0000-0001-5440-7701"]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]},{"id":"https://openalex.org/I4391768268","display_name":"State Key Laboratory of Virology","ror":"https://ror.org/05sqd2v93","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I37461747","https://openalex.org/I4210106882","https://openalex.org/I4391768268"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Linlin Xie","raw_affiliation_strings":["State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China","institution_ids":["https://openalex.org/I37461747","https://openalex.org/I4391768268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100706858","display_name":"Yan Teng","orcid":"https://orcid.org/0000-0003-2186-3270","observed_orcids":["https://orcid.org/0000-0003-2186-3270"]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]},{"id":"https://openalex.org/I4391768268","display_name":"State Key Laboratory of Virology","ror":"https://ror.org/05sqd2v93","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I37461747","https://openalex.org/I4210106882","https://openalex.org/I4391768268"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan Teng","raw_affiliation_strings":["State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China","institution_ids":["https://openalex.org/I37461747","https://openalex.org/I4391768268"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Zhiyu Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]},{"id":"https://openalex.org/I4391768268","display_name":"State Key Laboratory of Virology","ror":"https://ror.org/05sqd2v93","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I37461747","https://openalex.org/I4210106882","https://openalex.org/I4391768268"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhiyu Liu","raw_affiliation_strings":["State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China","institution_ids":["https://openalex.org/I37461747","https://openalex.org/I4391768268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100872272","display_name":"Luo Fan","orcid":"https://orcid.org/0000-0001-9812-2476","observed_orcids":["https://orcid.org/0000-0001-9812-2476"]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]},{"id":"https://openalex.org/I4391768268","display_name":"State Key Laboratory of Virology","ror":"https://ror.org/05sqd2v93","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I37461747","https://openalex.org/I4210106882","https://openalex.org/I4391768268"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fan Luo","raw_affiliation_strings":["State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China","institution_ids":["https://openalex.org/I37461747","https://openalex.org/I4391768268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084621356","display_name":"Hairong Xiong","orcid":"https://orcid.org/0000-0002-4028-0639","observed_orcids":["https://orcid.org/0000-0002-4028-0639"]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]},{"id":"https://openalex.org/I4391768268","display_name":"State Key Laboratory of Virology","ror":"https://ror.org/05sqd2v93","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I37461747","https://openalex.org/I4210106882","https://openalex.org/I4391768268"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hairong Xiong","raw_affiliation_strings":["State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China","institution_ids":["https://openalex.org/I37461747","https://openalex.org/I4391768268"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yan Zeng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I119454577","display_name":"Nanjing Agricultural University","ror":"https://ror.org/05td3s095","country_code":"CN","type":"education","lineage":["https://openalex.org/I119454577"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan Zeng","raw_affiliation_strings":["Department of Zoology, College of Life Sciences, Nanjing Agriculture University, Nanjing, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Zoology, College of Life Sciences, Nanjing Agriculture University, Nanjing, People's Republic of China","institution_ids":["https://openalex.org/I119454577"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Wei Hou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]},{"id":"https://openalex.org/I4391768268","display_name":"State Key Laboratory of Virology","ror":"https://ror.org/05sqd2v93","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I37461747","https://openalex.org/I4210106882","https://openalex.org/I4391768268"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wei Hou","raw_affiliation_strings":["State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China","institution_ids":["https://openalex.org/I37461747","https://openalex.org/I4391768268"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063385377","display_name":"Yong Feng","orcid":"https://orcid.org/0000-0003-1590-0186","observed_orcids":["https://orcid.org/0000-0003-1590-0186"]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]},{"id":"https://openalex.org/I4210120234","display_name":"Zhongnan Hospital of Wuhan University","ror":"https://ror.org/01v5mqw79","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210120234"]},{"id":"https://openalex.org/I4391768268","display_name":"State Key Laboratory of Virology","ror":"https://ror.org/05sqd2v93","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I37461747","https://openalex.org/I4210106882","https://openalex.org/I4391768268"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yong Feng","raw_affiliation_strings":["State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China","Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, People's Republic of China","institution_ids":["https://openalex.org/I37461747","https://openalex.org/I4391768268"]},{"raw_affiliation_string":"Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China","institution_ids":["https://openalex.org/I4210120234"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5063385377"],"corresponding_institution_ids":["https://openalex.org/I37461747","https://openalex.org/I4210120234","https://openalex.org/I4391768268"],"apc_list":null,"apc_paid":null,"fwci":0.4533,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.51612248,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":92,"max":97},"biblio":{"volume":"34","issue":"7","first_page":"580","last_page":"589"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.7529000043869019,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.7529000043869019,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.22310000658035278,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11532","display_name":"Chemokine receptors and signaling","score":0.008700000122189522,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mir-146a","display_name":"miR-146a","score":0.9789999723434448},{"id":"https://openalex.org/keywords/hiv-1-infection","display_name":"HIV-1 infection","score":0.9100000262260437},{"id":"https://openalex.org/keywords/ccl5","display_name":"RANTES","score":0.9919999837875366},{"id":"https://openalex.org/keywords/chemokine-regulation","display_name":"chemokine regulation","score":0.5860000252723694},{"id":"https://openalex.org/keywords/macrophages","display_name":"macrophages","score":0.9409999847412109},{"id":"https://openalex.org/keywords/monocyte-migration","display_name":"monocyte migration","score":0.9980000257492065},{"id":"https://openalex.org/keywords/3-untranslated-region","display_name":"3' untranslated region","score":0.8479999899864197},{"id":"https://openalex.org/keywords/post-transcriptional-regulation","display_name":"post-transcriptional regulation","score":0.890999972820282},{"id":"https://openalex.org/keywords/chemokine-secretion","display_name":"chemokine secretion","score":0.5989999771118164},{"id":"https://openalex.org/keywords/hiv-pathogenesis","display_name":"HIV pathogenesis","score":0.7459999918937683}],"concepts":[{"id":"https://openalex.org/C116484652","wikidata":"https://www.wikidata.org/wiki/Q3492926","display_name":"CCL5","level":5,"score":0.7308535575866699},{"id":"https://openalex.org/C2781184567","wikidata":"https://www.wikidata.org/wiki/Q107244","display_name":"Monocyte","level":2,"score":0.7110893726348877},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.6922180652618408},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.49698999524116516},{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.4915045201778412},{"id":"https://openalex.org/C2779690655","wikidata":"https://www.wikidata.org/wiki/Q374232","display_name":"Lentivirus","level":4,"score":0.4574410915374756},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.44590556621551514},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.43708541989326477},{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.4126524329185486},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3967694044113159},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3766477704048157},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.28795063495635986},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.1751309037208557},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.15954157710075378},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.15414893627166748},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.13072630763053894},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12515482306480408},{"id":"https://openalex.org/C79484868","wikidata":"https://www.wikidata.org/wiki/Q5971673","display_name":"IL-2 receptor","level":4,"score":0.0718420147895813}],"mesh":[{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D018946","descriptor_name":"Chemokine CCL5","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1089/aid.2017.0217","doi":"https://doi.org/10.1089/aid.2017.0217","is_oa":false,"landing_page_url":"https://doi.org/10.1089/aid.2017.0217","pdf_url":null,"source":{"id":"https://openalex.org/S161282271","display_name":"AIDS Research and Human Retroviruses","issn_l":"0889-2229","issn":["0889-2229","1931-8405"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS Research and Human Retroviruses","raw_type":"journal-article"},{"id":"pmid:29717615","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29717615","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS research and human retroviruses","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W144423133","https://openalex.org/W1596100394","https://openalex.org/W1889803280","https://openalex.org/W1965893507","https://openalex.org/W1966064265","https://openalex.org/W1968045213","https://openalex.org/W1974299402","https://openalex.org/W1977797184","https://openalex.org/W1996336047","https://openalex.org/W2004432444","https://openalex.org/W2007431542","https://openalex.org/W2014946489","https://openalex.org/W2015878280","https://openalex.org/W2030514786","https://openalex.org/W2032812716","https://openalex.org/W2037241579","https://openalex.org/W2043849781","https://openalex.org/W2045881743","https://openalex.org/W2047516222","https://openalex.org/W2056364365","https://openalex.org/W2075860675","https://openalex.org/W2076449784","https://openalex.org/W2076748892","https://openalex.org/W2078569743","https://openalex.org/W2085099489","https://openalex.org/W2098671498","https://openalex.org/W2112513114","https://openalex.org/W2114193711","https://openalex.org/W2121626541","https://openalex.org/W2130733957","https://openalex.org/W2133613657","https://openalex.org/W2134629862","https://openalex.org/W2136059996","https://openalex.org/W2137138056","https://openalex.org/W2143036044","https://openalex.org/W2148974698","https://openalex.org/W2150361201","https://openalex.org/W2160306636","https://openalex.org/W2164961790","https://openalex.org/W2167646969","https://openalex.org/W2172688163","https://openalex.org/W2215729635","https://openalex.org/W2253271604","https://openalex.org/W2287467316","https://openalex.org/W2738272913"],"related_works":["https://openalex.org/W2112513114","https://openalex.org/W1996336047","https://openalex.org/W2071396452","https://openalex.org/W2075355211","https://openalex.org/W1986015261","https://openalex.org/W2013407479","https://openalex.org/W2146677466","https://openalex.org/W7096247248","https://openalex.org/W6992798068","https://openalex.org/W2024322137"],"abstract_inverted_index":{"MicroRNAs":[0],"(miRNAs)":[1],"are":[2],"widely":[3],"involved":[4],"in":[5,21,35,49,59,74,103],"immune":[6],"regulation":[7,73],"during":[8,152],"virus":[9,24],"infection.":[10],"Several":[11],"studies":[12,82],"showed":[13,83],"that":[14,84,110,120],"the":[15,30,67,90,147],"expression":[16],"of":[17,33,42,69,80,89,143,146],"miR-146a":[18,34,70,91,94,98,111,121,151],"was":[19],"increased":[20,100],"human":[22],"immunodeficiency":[23],"type":[25],"I":[26],"(HIV-1)-infected":[27],"cells,":[28],"but":[29],"definitive":[31],"function":[32,81],"HIV-1":[36],"infection":[37],"remains":[38],"obscure.":[39],"The":[40],"production":[41,102],"chemokine":[43,148],"(C-C":[44],"motif)":[45],"ligand":[46],"5":[47],"(CCL5)":[48],"macrophages":[50],"has":[51],"been":[52],"reported":[53],"to":[54,158],"play":[55],"an":[56],"important":[57],"role":[58],"HIV/AIDS-associated":[60],"pathogenesis.":[61,160],"In":[62,106],"this":[63],"study,":[64],"we":[65,108],"examined":[66],"effects":[68],"on":[71],"CCL5":[72,85,101,123,149],"HIV-1-infected":[75,104],"macrophages.":[76,105],"Gain":[77],"and":[78,132],"loss":[79],"might":[86,156],"be":[87],"one":[88],"targets,":[92],"as":[93],"mimic":[95],"reduced,":[96],"while":[97],"inhibitor":[99],"addition,":[107],"demonstrated":[109],"reduced":[112],"CCL5-induced":[113],"monocyte":[114,134],"migration.":[115],"Our":[116],"study":[117],"provided":[118],"evidence":[119],"targets":[122],"3'":[124],"untranslated":[125],"regions,":[126],"downregulates":[127],"its":[128],"release":[129],"from":[130],"macrophages,":[131],"affects":[133],"migration":[135],"consequently.":[136],"These":[137],"findings":[138],"drew":[139],"a":[140],"novel":[141],"layer":[142],"posttranscriptional":[144],"control":[145],"by":[150],"HIV":[153,159],"infection,":[154],"which":[155],"contribute":[157]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2018-05-17T00:00:00"}
