{"id":"https://openalex.org/W2796648332","doi":null,"title":"Points of Leverage: Interrupting the Intergenerational Transmission of Adversity","display_name":"Points of Leverage: Interrupting the Intergenerational Transmission of Adversity","publication_year":2017,"publication_date":"2017-01-01","ids":{"openalex":"https://openalex.org/W2796648332","mag":"2796648332"},"language":"en","primary_location":{"id":"pmh:oai:digitalcommons.du.edu:etd-2357","doi":null,"is_oa":true,"landing_page_url":"https://digitalcommons.du.edu/etd/1357","pdf_url":"https://digitalcommons.du.edu/etd/1357","source":{"id":"https://openalex.org/S4377196520","display_name":"Digital Commons - DU (University of Denver)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I131651094","host_organization_name":"University of Denver","host_organization_lineage":["https://openalex.org/I131651094"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Electronic Theses and Dissertations","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://digitalcommons.du.edu/etd/1357","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044240009","display_name":"Lisa J. Schlueter","orcid":"https://orcid.org/0000-0003-2949-5759","observed_orcids":["https://orcid.org/0000-0003-2949-5759"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Lisa Schlueter","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2949-5759","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5044240009"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.3006061,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10426","display_name":"Child Abuse and Trauma","score":0.8154000043869019,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10426","display_name":"Child Abuse and Trauma","score":0.8154000043869019,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.10660000145435333,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10182","display_name":"Child and Adolescent Psychosocial and Emotional Development","score":0.026000000536441803,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/early-life-stress","display_name":"early life stress","score":0.7260000109672546},{"id":"https://openalex.org/keywords/diurnal-cortisol","display_name":"diurnal cortisol","score":0.878000020980835},{"id":"https://openalex.org/keywords/stress-reactivity","display_name":"stress reactivity","score":0.8119999766349792},{"id":"https://openalex.org/keywords/caregiver-mental-health","display_name":"caregiver mental health","score":0.9179999828338623},{"id":"https://openalex.org/keywords/environmental-instability","display_name":"environmental instability","score":0.9829999804496765},{"id":"https://openalex.org/keywords/epigenetic-methylation","display_name":"epigenetic methylation","score":0.8429999947547913},{"id":"https://openalex.org/keywords/early-head-start","display_name":"Early Head Start","score":0.8080000281333923},{"id":"https://openalex.org/keywords/latino-families","display_name":"Latino families","score":0.8510000109672546},{"id":"https://openalex.org/keywords/low-income-households","display_name":"low-income households","score":0.9100000262260437},{"id":"https://openalex.org/keywords/mediating-and-moderating-effects","display_name":"mediating and moderating effects","score":0.49300000071525574}],"concepts":[{"id":"https://openalex.org/C153083717","wikidata":"https://www.wikidata.org/wiki/Q6535263","display_name":"Leverage (statistics)","level":2,"score":0.663260281085968},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4235011041164398},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3152851462364197},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.13095077872276306}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:digitalcommons.du.edu:etd-2357","doi":null,"is_oa":true,"landing_page_url":"https://digitalcommons.du.edu/etd/1357","pdf_url":"https://digitalcommons.du.edu/etd/1357","source":{"id":"https://openalex.org/S4377196520","display_name":"Digital Commons - DU (University of Denver)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I131651094","host_organization_name":"University of Denver","host_organization_lineage":["https://openalex.org/I131651094"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Electronic Theses and Dissertations","raw_type":"text"},{"id":"mag:2796648332","doi":null,"is_oa":false,"landing_page_url":"https://digitalcommons.du.edu/cgi/viewcontent.cgi?article=2357&context=etd","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:digitalcommons.du.edu:etd-2357","doi":null,"is_oa":true,"landing_page_url":"https://digitalcommons.du.edu/etd/1357","pdf_url":"https://digitalcommons.du.edu/etd/1357","source":{"id":"https://openalex.org/S4377196520","display_name":"Digital Commons - DU (University of Denver)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I131651094","host_organization_name":"University of Denver","host_organization_lineage":["https://openalex.org/I131651094"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Electronic Theses and Dissertations","raw_type":"text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2796648332.pdf","grobid_xml":"https://content.openalex.org/works/W2796648332.grobid-xml"},"referenced_works_count":81,"referenced_works":["https://openalex.org/W602062237","https://openalex.org/W1732622108","https://openalex.org/W1954049365","https://openalex.org/W1969625130","https://openalex.org/W1969639624","https://openalex.org/W1971984381","https://openalex.org/W1978019464","https://openalex.org/W1984427714","https://openalex.org/W1986577113","https://openalex.org/W1988985751","https://openalex.org/W1994706471","https://openalex.org/W1998622547","https://openalex.org/W2001187532","https://openalex.org/W2001711719","https://openalex.org/W2005508165","https://openalex.org/W2006419493","https://openalex.org/W2008485227","https://openalex.org/W2013621624","https://openalex.org/W2018653636","https://openalex.org/W2020291009","https://openalex.org/W2027051643","https://openalex.org/W2033442056","https://openalex.org/W2036835415","https://openalex.org/W2043410201","https://openalex.org/W2043583999","https://openalex.org/W2049967622","https://openalex.org/W2056248606","https://openalex.org/W2059165843","https://openalex.org/W2060103188","https://openalex.org/W2072524808","https://openalex.org/W2076008204","https://openalex.org/W2078965693","https://openalex.org/W2085209809","https://openalex.org/W2086858304","https://openalex.org/W2088068432","https://openalex.org/W2091413411","https://openalex.org/W2093358121","https://openalex.org/W2093445835","https://openalex.org/W2097113612","https://openalex.org/W2101708080","https://openalex.org/W2102132607","https://openalex.org/W2102926673","https://openalex.org/W2105194498","https://openalex.org/W2106670153","https://openalex.org/W2110948307","https://openalex.org/W2112778345","https://openalex.org/W2114926006","https://openalex.org/W2115217290","https://openalex.org/W2116629441","https://openalex.org/W2116778476","https://openalex.org/W2116839388","https://openalex.org/W2117486684","https://openalex.org/W2119517726","https://openalex.org/W2120839478","https://openalex.org/W2125136250","https://openalex.org/W2127363947","https://openalex.org/W2132539548","https://openalex.org/W2136337391","https://openalex.org/W2140219025","https://openalex.org/W2141141027","https://openalex.org/W2141536144","https://openalex.org/W2141709307","https://openalex.org/W2143881724","https://openalex.org/W2144793442","https://openalex.org/W2147732539","https://openalex.org/W2148337554","https://openalex.org/W2155088814","https://openalex.org/W2156188202","https://openalex.org/W2156303855","https://openalex.org/W2156579478","https://openalex.org/W2159320937","https://openalex.org/W2160251605","https://openalex.org/W2160989708","https://openalex.org/W2170760271","https://openalex.org/W2171170090","https://openalex.org/W2181550935","https://openalex.org/W2181898216","https://openalex.org/W2261260426","https://openalex.org/W2465880609","https://openalex.org/W2525950056","https://openalex.org/W4245933202"],"related_works":["https://openalex.org/W4399088088","https://openalex.org/W2042519735","https://openalex.org/W4317182263","https://openalex.org/W4414642878","https://openalex.org/W4311206224","https://openalex.org/W2951232749","https://openalex.org/W2766457111","https://openalex.org/W2052428115","https://openalex.org/W4235768274","https://openalex.org/W2043867072"],"abstract_inverted_index":{"Early":[0,96],"life":[1,27,188],"stressors,":[2],"such":[3,315],"as":[4],"abuse":[5],"and":[6,14,38,48,51,75,111,114,127,141,152,166,168,183,185,197,204,214,237,239,242,258,260,278,292,297,309,312,319,324,328,330,341,369,380],"neglect,":[7],"have":[8,30,77],"been":[9,80],"associated":[10],"with":[11],"poor":[12],"physical":[13],"mental":[15,121,225],"health":[16,37,226],"outcomes":[17,76],"in":[18,68,83,95,367,371],"adulthood.":[19],"Moreover,":[20],"animal":[21,44],"models":[22,45],"suggest":[23,346],"that":[24,33,174,222,316],"caregivers'":[25],"early":[26,187],"stress":[28,73,144,170,216,364],"can":[29,66],"intergenerational":[31],"effects":[32,133,301,354],"then":[34],"impact":[35],"the":[36,100,132,158,230,251,283,300,353],"well-being":[39],"of":[40,63,89,107,134,137,164,193,235,256,282,302,305,334,352,355,358,374],"their":[41,71],"offspring.":[42],"Although":[43],"are":[46,54],"compelling,":[47],"inter-generationally":[49],"transmitted":[50],"co-occurring":[52],"risks":[53],"well-documented,":[55],"proximal":[56,347],"mechanistic":[57],"explanations":[58],"for":[59,177,212,267,350],"how":[60],"caregiver's":[61],"history":[62,106,136,163,192,234,255,304,333,357],"childhood":[64],"adversity":[65,108,138,165,194,236,257,272,306,335,359],"result":[67],"changes":[69],"to":[70,276],"child's":[72],"physiology":[74],"not":[78,274,363],"yet":[79],"systematically":[81],"tested":[82],"humans.":[84],"Thus,":[85],"among":[86],"a":[87,372],"sample":[88,373],"low-income,":[90],"predominantly":[91],"Latino":[92],"families":[93,375],"participating":[94],"Head":[97],"Start":[98],"(EHS),":[99],"current":[101,223,378],"study":[102],"explored":[103,148],"whether":[104,149],"caregiver":[105,135,150,162,181,191,224,233,254,290,295,303,332,356],"predicted":[109,195],"infant":[110,140,167,196,213,238,259,277,308],"toddler":[112,142,169,198,215,240,261,279,310],"physiology,":[113],"if":[115],"three":[116],"pathways,":[117],"one":[118,123,128],"psychological":[119],"(caregiver":[120],"health),":[122],"physical/environmental":[124],"(environmental":[125],"instability),":[126],"biological":[129],"(epigenetic),":[130],"mediated":[131,155,229,250],"on":[139,307,360],"dysregulated":[143],"physiology.":[145,171],"I":[146],"also":[147],"warmth":[151,291,296,323],"responsivity":[153,298,325],"either":[154],"or":[156],"moderated":[157,299],"direct":[159],"relationship":[160,209,231,252],"between":[161,232,253],"Results":[172,345],"showed":[173],"after":[175],"controlling":[176],"important":[178],"covariates":[179],"(income-to-needs,":[180],"race":[182],"ethnicity,":[184],"child":[186],"stress),":[189],"higher":[190,202],"diurnal":[199],"cortisol":[200,244,269,314,343,366],"(e.g.,":[201],"noon":[203,241,262,311,340],"bedtime":[205,243,268,313,342],"values),":[206],"but":[207,264,362],"no":[208],"was":[210,265,273],"found":[211],"reactivity":[217],"cortisol.":[218],"Mediation":[219],"analyses":[220],"demonstrated":[221],"symptoms":[227],"partially":[228],"values.":[245,270,344],"Further,":[246],"environmental":[247],"instability":[248],"fully":[249],"cortisol,":[263],"non-significant":[266],"Caregiver":[271],"related":[275],"methylation":[280],"rates":[281],"human":[284],"glucocorticoid":[285],"receptor":[286],"gene":[287],"NR3C1,":[288],"nor":[289],"responsivity.":[293],"However,":[294],"when":[317],"infants":[318,368],"toddlers":[320,370],"experienced":[321,337],"lower":[322],"(both":[326],"chronically":[327],"acutely)":[329],"high":[331,339],"they":[336],"particularly":[338],"processes":[348],"account":[349],"many":[351],"diurnal,":[361],"reactive,":[365],"experiencing":[376],"significant":[377],"economic":[379],"psychosocial":[381],"adversity.":[382]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2018-04-24T00:00:00"}
