{"id":"https://openalex.org/W2792291600","doi":"https://doi.org/10.1016/j.coi.2018.03.008","title":"Oncolytic viruses and immunity","display_name":"Oncolytic viruses and immunity","publication_year":2018,"publication_date":"2018-03-15","ids":{"openalex":"https://openalex.org/W2792291600","doi":"https://doi.org/10.1016/j.coi.2018.03.008","mag":"2792291600","pmid":"https://pubmed.ncbi.nlm.nih.gov/29550660","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9285655"},"language":"en","primary_location":{"id":"doi:10.1016/j.coi.2018.03.008","doi":"https://doi.org/10.1016/j.coi.2018.03.008","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.coi.2018.03.008","pdf_url":null,"source":{"id":"https://openalex.org/S170047187","display_name":"Current Opinion in Immunology","issn_l":"0952-7915","issn":["0952-7915","1879-0372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Immunology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9285655","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067353931","display_name":"Shyambabu Chaurasiya","orcid":"https://orcid.org/0000-0002-9543-5458","observed_orcids":["https://orcid.org/0000-0002-9543-5458"]},"institutions":[{"id":"https://openalex.org/I1301076528","display_name":"City Of Hope National Medical Center","ror":"https://ror.org/00w6g5w60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shyambabu Chaurasiya","raw_affiliation_strings":["Department of Surgery, City of Hope National Medical Center, Duarte, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, City of Hope National Medical Center, Duarte, CA, USA","institution_ids":["https://openalex.org/I1301076528"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003999618","display_name":"Nanhai G. Chen","orcid":"https://orcid.org/0000-0002-0783-2665","observed_orcids":["https://orcid.org/0000-0002-0783-2665"]},"institutions":[{"id":"https://openalex.org/I1301076528","display_name":"City Of Hope National Medical Center","ror":"https://ror.org/00w6g5w60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528"]},{"id":"https://openalex.org/I4387156432","display_name":"Beckman Research Institute","ror":"https://ror.org/05fazth07","country_code":"US","type":"facility","lineage":["https://openalex.org/I1301076528","https://openalex.org/I4387156432"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nanhai G Chen","raw_affiliation_strings":["Department of Surgery, City of Hope National Medical Center, Duarte, CA, USA; Center for Gene Therapy, Department of Hematology and Hematopoietic Cell Transplantation, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA, USA; Gene Editing and Viral Vector Core, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA, USA","Center for Gene Therapy, Department of Hematology and Hematopoietic Cell Transplantation, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA, USA","Department of Surgery, City of Hope National Medical Center, Duarte, CA, USA","Gene Editing and Viral Vector Core, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, City of Hope National Medical Center, Duarte, CA, USA; Center for Gene Therapy, Department of Hematology and Hematopoietic Cell Transplantation, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA, USA; Gene Editing and Viral Vector Core, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA, USA","institution_ids":["https://openalex.org/I1301076528","https://openalex.org/I4387156432"]},{"raw_affiliation_string":"Center for Gene Therapy, Department of Hematology and Hematopoietic Cell Transplantation, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA, USA","institution_ids":["https://openalex.org/I1301076528","https://openalex.org/I4387156432"]},{"raw_affiliation_string":"Department of Surgery, City of Hope National Medical Center, Duarte, CA, USA","institution_ids":["https://openalex.org/I1301076528"]},{"raw_affiliation_string":"Gene Editing and Viral Vector Core, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA, USA","institution_ids":["https://openalex.org/I1301076528","https://openalex.org/I4387156432"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005824918","display_name":"Yuman Fong","orcid":"https://orcid.org/0000-0002-8934-9959","observed_orcids":["https://orcid.org/0000-0002-8934-9959"]},"institutions":[{"id":"https://openalex.org/I1301076528","display_name":"City Of Hope National Medical Center","ror":"https://ror.org/00w6g5w60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528"]},{"id":"https://openalex.org/I4387156432","display_name":"Beckman Research Institute","ror":"https://ror.org/05fazth07","country_code":"US","type":"facility","lineage":["https://openalex.org/I1301076528","https://openalex.org/I4387156432"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Yuman Fong","raw_affiliation_strings":["Department of Surgery, City of Hope National Medical Center, Duarte, CA, USA; Center for Gene Therapy, Department of Hematology and Hematopoietic Cell Transplantation, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA, USA. Electronic address: yfong@coh.org","Center for Gene Therapy, Department of Hematology and Hematopoietic Cell Transplantation, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA, USA","Department of Surgery, City of Hope National Medical Center, Duarte, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, City of Hope National Medical Center, Duarte, CA, USA; Center for Gene Therapy, Department of Hematology and Hematopoietic Cell Transplantation, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA, USA. Electronic address: yfong@coh.org","institution_ids":["https://openalex.org/I1301076528","https://openalex.org/I4387156432"]},{"raw_affiliation_string":"Center for Gene Therapy, Department of Hematology and Hematopoietic Cell Transplantation, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA, USA","institution_ids":["https://openalex.org/I1301076528","https://openalex.org/I4387156432"]},{"raw_affiliation_string":"Department of Surgery, City of Hope National Medical Center, Duarte, CA, USA","institution_ids":["https://openalex.org/I1301076528"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5005824918"],"corresponding_institution_ids":["https://openalex.org/I1301076528","https://openalex.org/I4387156432"],"apc_list":{"value":4410,"currency":"USD","value_usd":4410},"apc_paid":null,"fwci":1.3848,"has_fulltext":false,"cited_by_count":107,"citation_normalized_percentile":{"value":0.82033898,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"51","issue":null,"first_page":"83","last_page":"90"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oncolytic-viruses","display_name":"oncolytic viruses","score":0.949999988079071},{"id":"https://openalex.org/keywords/oncolytic-virotherapy","display_name":"oncolytic virotherapy","score":0.9980000257492065},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.671999990940094},{"id":"https://openalex.org/keywords/adaptive-immunity","display_name":"adaptive immunity","score":1.0},{"id":"https://openalex.org/keywords/tumor-immune-microenvironment","display_name":"tumor immune microenvironment","score":0.5509999990463257},{"id":"https://openalex.org/keywords/combination-immunotherapy","display_name":"combination immunotherapy","score":0.8320000171661377},{"id":"https://openalex.org/keywords/antitumor-immunity","display_name":"antitumor immunity","score":0.6710000038146973}],"concepts":[{"id":"https://openalex.org/C82210918","wikidata":"https://www.wikidata.org/wiki/Q1560099","display_name":"Oncolytic virus","level":3,"score":0.9567715525627136},{"id":"https://openalex.org/C49744831","wikidata":"https://www.wikidata.org/wiki/Q600121","display_name":"Virotherapy","level":4,"score":0.7925409078598022},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6430705785751343},{"id":"https://openalex.org/C193419808","wikidata":"https://www.wikidata.org/wiki/Q1645075","display_name":"Acquired immune system","level":3,"score":0.6212369203567505},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.5922311544418335},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.47812119126319885},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.46113407611846924},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4432711601257324},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.44071370363235474},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.32734569907188416}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003131","descriptor_name":"Combined Modality Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005822","descriptor_name":"Genetic Vectors","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007109","descriptor_name":"Immunity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D016923","descriptor_name":"Cell Death","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D050130","descriptor_name":"Oncolytic Virotherapy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D050130","descriptor_name":"Oncolytic Virotherapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D050504","descriptor_name":"Oncolytic Viruses","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D056704","descriptor_name":"Adaptive Immunity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056747","descriptor_name":"Immunomodulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.coi.2018.03.008","doi":"https://doi.org/10.1016/j.coi.2018.03.008","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.coi.2018.03.008","pdf_url":null,"source":{"id":"https://openalex.org/S170047187","display_name":"Current Opinion in Immunology","issn_l":"0952-7915","issn":["0952-7915","1879-0372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Immunology","raw_type":"journal-article"},{"id":"pmid:29550660","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29550660","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current opinion in immunology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9285655","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9285655","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Curr Opin Immunol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:9285655","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9285655","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Curr Opin Immunol","raw_type":"Text"},"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G9000889907","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA033572","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":74,"referenced_works":["https://openalex.org/W159782486","https://openalex.org/W1491631791","https://openalex.org/W1542691850","https://openalex.org/W1827720726","https://openalex.org/W1854596437","https://openalex.org/W1888836615","https://openalex.org/W1967262248","https://openalex.org/W1973901905","https://openalex.org/W1976041409","https://openalex.org/W1985995901","https://openalex.org/W1989295263","https://openalex.org/W1993282202","https://openalex.org/W1996515420","https://openalex.org/W1999102084","https://openalex.org/W2000952771","https://openalex.org/W2008620560","https://openalex.org/W2016525911","https://openalex.org/W2023310830","https://openalex.org/W2024209265","https://openalex.org/W2026144469","https://openalex.org/W2032530158","https://openalex.org/W2038840324","https://openalex.org/W2040400654","https://openalex.org/W2047902191","https://openalex.org/W2060222040","https://openalex.org/W2062368814","https://openalex.org/W2063560415","https://openalex.org/W2066671159","https://openalex.org/W2068084816","https://openalex.org/W2069272353","https://openalex.org/W2078414780","https://openalex.org/W2079376474","https://openalex.org/W2082150850","https://openalex.org/W2083381116","https://openalex.org/W2086591619","https://openalex.org/W2087055812","https://openalex.org/W2087984814","https://openalex.org/W2090599158","https://openalex.org/W2091123311","https://openalex.org/W2092601545","https://openalex.org/W2095394300","https://openalex.org/W2099648846","https://openalex.org/W2101058247","https://openalex.org/W2102833781","https://openalex.org/W2106248075","https://openalex.org/W2109274792","https://openalex.org/W2114443495","https://openalex.org/W2117692326","https://openalex.org/W2123469465","https://openalex.org/W2124221114","https://openalex.org/W2127283062","https://openalex.org/W2128892990","https://openalex.org/W2141669181","https://openalex.org/W2144491853","https://openalex.org/W2154428464","https://openalex.org/W2165320653","https://openalex.org/W2167451108","https://openalex.org/W2169788601","https://openalex.org/W2252869735","https://openalex.org/W2313228602","https://openalex.org/W2324106738","https://openalex.org/W2331948039","https://openalex.org/W2463868563","https://openalex.org/W2547558000","https://openalex.org/W2560367415","https://openalex.org/W2587048937","https://openalex.org/W2612087699","https://openalex.org/W2615468880","https://openalex.org/W2624117248","https://openalex.org/W2744246163","https://openalex.org/W2750781282","https://openalex.org/W2752308768","https://openalex.org/W4211238487","https://openalex.org/W6737675732"],"related_works":["https://openalex.org/W4387873477","https://openalex.org/W2801067660","https://openalex.org/W2999300004","https://openalex.org/W2618834187","https://openalex.org/W3193415821","https://openalex.org/W2029055826","https://openalex.org/W2032795930","https://openalex.org/W1976041409","https://openalex.org/W2156823146","https://openalex.org/W4200054811"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":14},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":18},{"year":2019,"cited_by_count":10},{"year":2018,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-03-29T00:00:00"}