{"id":"https://openalex.org/W2790340503","doi":"https://doi.org/10.7326/l17-0700","title":"Prescription Opioid Use, Misuse, and Use Disorders in U.S. Adults","display_name":"Prescription Opioid Use, Misuse, and Use Disorders in U.S. Adults","publication_year":2018,"publication_date":"2018-03-05","ids":{"openalex":"https://openalex.org/W2790340503","doi":"https://doi.org/10.7326/l17-0700","mag":"2790340503","pmid":"https://pubmed.ncbi.nlm.nih.gov/29507965"},"language":"en","primary_location":{"id":"doi:10.7326/l17-0700","doi":"https://doi.org/10.7326/l17-0700","is_oa":false,"landing_page_url":"https://doi.org/10.7326/l17-0700","pdf_url":null,"source":{"id":"https://openalex.org/S119722071","display_name":"Annals of Internal Medicine","issn_l":"0003-4819","issn":["0003-4819","1539-3704"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316812","host_organization_name":"American College of Physicians","host_organization_lineage":["https://openalex.org/P4310316812"],"host_organization_lineage_names":["American College of Physicians"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Internal Medicine","raw_type":"journal-article"},"volume":null,"type":"letter","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044062048","display_name":"Beth Han","orcid":"https://orcid.org/0000-0002-3861-1099","observed_orcids":["https://orcid.org/0000-0002-3861-1099"]},"institutions":[{"id":"https://openalex.org/I1336377119","display_name":"Substance Abuse and Mental Health Services Administration","ror":"https://ror.org/03t3qg659","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1336377119"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Beth Han","raw_affiliation_strings":["Substance Abuse and Mental Health Services Administration, Rockville, Maryland (B.H., C.M.J.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Substance Abuse and Mental Health Services Administration, Rockville, Maryland (B.H., C.M.J.)","institution_ids":["https://openalex.org/I1336377119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010643468","display_name":"Wilson M. Compton","orcid":"https://orcid.org/0000-0003-3108-5118","observed_orcids":["https://orcid.org/0000-0003-3108-5118"]},"institutions":[{"id":"https://openalex.org/I1327069482","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I1327069482"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wilson M. Compton","raw_affiliation_strings":["National Institute on Drug Abuse, Bethesda, Maryland (W.M.C., C.B.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute on Drug Abuse, Bethesda, Maryland (W.M.C., C.B.)","institution_ids":["https://openalex.org/I1327069482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015270347","display_name":"Carlos Blanco","orcid":"https://orcid.org/0000-0001-6187-3057","observed_orcids":["https://orcid.org/0000-0001-6187-3057","https://orcid.org/0009-0009-0244-3503"]},"institutions":[{"id":"https://openalex.org/I1327069482","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I1327069482"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carlos Blanco","raw_affiliation_strings":["National Institute on Drug Abuse, Bethesda, Maryland (W.M.C., C.B.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute on Drug Abuse, Bethesda, Maryland (W.M.C., C.B.)","institution_ids":["https://openalex.org/I1327069482"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008547559","display_name":"Christopher McCall Jones","orcid":"https://orcid.org/0000-0001-8598-2100","observed_orcids":["https://orcid.org/0000-0001-8598-2100"]},"institutions":[{"id":"https://openalex.org/I1336377119","display_name":"Substance Abuse and Mental Health Services Administration","ror":"https://ror.org/03t3qg659","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1336377119"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher M. Jones","raw_affiliation_strings":["Substance Abuse and Mental Health Services Administration, Rockville, Maryland (B.H., C.M.J.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Substance Abuse and Mental Health Services Administration, Rockville, Maryland (B.H., C.M.J.)","institution_ids":["https://openalex.org/I1336377119"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"168","issue":"5","first_page":"383","last_page":"384"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10576","display_name":"Opioid Use Disorder Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10576","display_name":"Opioid Use Disorder Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10043","display_name":"Substance Abuse Treatment and Outcomes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11199","display_name":"Pain Management and Opioid Use","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prescription-opioid-use","display_name":"prescription opioid use","score":0.8489999771118164},{"id":"https://openalex.org/keywords/prescription-opioid-misuse","display_name":"prescription opioid misuse","score":0.9520000219345093},{"id":"https://openalex.org/keywords/prescription-opioid-use-disorder","display_name":"prescription opioid use disorder","score":0.8339999914169312},{"id":"https://openalex.org/keywords/pain-relievers","display_name":"pain relievers","score":0.6899999976158142},{"id":"https://openalex.org/keywords/national-survey-on-drug-use-and-health","display_name":"National Survey on Drug Use and Health","score":0.7649999856948853},{"id":"https://openalex.org/keywords/substance-use-disorders","display_name":"substance use disorders","score":0.3269999921321869},{"id":"https://openalex.org/keywords/treatment-coverage","display_name":"treatment coverage","score":0.3050000071525574},{"id":"https://openalex.org/keywords/united-states-adults","display_name":"United States adults","score":0.546999990940094},{"id":"https://openalex.org/keywords/opioid-prescribing-practices","display_name":"opioid prescribing practices","score":0.9760000109672546}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9151777029037476},{"id":"https://openalex.org/C2426938","wikidata":"https://www.wikidata.org/wiki/Q3355478","display_name":"Medical prescription","level":2,"score":0.6717010736465454},{"id":"https://openalex.org/C2781063702","wikidata":"https://www.wikidata.org/wiki/Q427523","display_name":"Opioid","level":3,"score":0.5035406947135925},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.46635735034942627},{"id":"https://openalex.org/C2909816603","wikidata":"https://www.wikidata.org/wiki/Q1639178","display_name":"Opioid-Related Disorders","level":5,"score":0.421235591173172},{"id":"https://openalex.org/C2779418921","wikidata":"https://www.wikidata.org/wiki/Q1639178","display_name":"Opioid use disorder","level":4,"score":0.411823570728302},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.33503252267837524},{"id":"https://openalex.org/C2777170798","wikidata":"https://www.wikidata.org/wiki/Q65087481","display_name":"Opioid epidemic","level":4,"score":0.3042546510696411},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.24956011772155762},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.20849871635437012},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009293","descriptor_name":"Opioid-Related Disorders","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063487","descriptor_name":"Prescription Drug Misuse","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.7326/l17-0700","doi":"https://doi.org/10.7326/l17-0700","is_oa":false,"landing_page_url":"https://doi.org/10.7326/l17-0700","pdf_url":null,"source":{"id":"https://openalex.org/S119722071","display_name":"Annals of Internal Medicine","issn_l":"0003-4819","issn":["0003-4819","1539-3704"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316812","host_organization_name":"American College of Physicians","host_organization_lineage":["https://openalex.org/P4310316812"],"host_organization_lineage_names":["American College of Physicians"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Internal Medicine","raw_type":"journal-article"},{"id":"pmid:29507965","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29507965","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of internal medicine","raw_type":"Letter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":3,"referenced_works":["https://openalex.org/W2041002668","https://openalex.org/W2314214487","https://openalex.org/W2416184435"],"related_works":["https://openalex.org/W2739913519","https://openalex.org/W2739669938","https://openalex.org/W4400576565","https://openalex.org/W2913993642","https://openalex.org/W2985001984","https://openalex.org/W2739081735","https://openalex.org/W2980329265","https://openalex.org/W2887870561","https://openalex.org/W7061539893","https://openalex.org/W2468306238"],"abstract_inverted_index":{"Letters6":[0],"March":[1,603,621,626],"2018Prescription":[2],"Opioid":[3,467,505,524,564],"Use,":[4,468,506],"Misuse,":[5,469,507],"and":[6,25,36,70,77,87,182,190,201,268,305,320,325,344,354,365,382,388,403,408,425,431,437,453,470,482,500,508,517,526,531,549,568,580,599,611,615],"Use":[7,189,471,481,509],"Disorders":[8,472,510],"in":[9,127,145,239,272,299,422,473,511,529,560,594],"U.S.":[10,384,474,512],"AdultsBeth":[11],"Han,":[12,31],"MD,":[13,19,23,32,48,60],"PhD,":[14,24,33],"MPH,":[15],"Wilson":[16,45,487],"M.":[17,27,46,72,488,502],"Compton,":[18,47],"MPE,":[20],"Carlos":[21,58,491],"Blanco,":[22,59],"Christopher":[26,71,501],"Jones,":[28,73],"PharmD,":[29,74],"MPHBeth":[30],"MPHSubstance":[34,75],"Abuse":[35,76,200,324,364,375],"Mental":[37,78,202,326,366],"Health":[38,79,180,191,203,241,327,367,387,483],"Services":[39,80,204,328,368],"Administration,":[40,81,329,369],"Rockville,":[41,82,330],"Maryland":[42,55,67,83,331,339],"(B.H.,":[43,84,332],"C.M.J.),":[44],"MPENational":[49],"Institute":[50,62,334,372],"on":[51,63,110,187,211,263,335,373,479,545],"Drug":[52,64,188,336,374,480],"Abuse,":[53,65,337],"Bethesda,":[54,66,338],"(W.M.C.,":[56,68,340],"C.B.),":[57,69],"PhDNational":[61],"C.M.J.)Author,":[85],"Article,":[86,319],"Disclosure":[88,321],"Informationhttps://doi.org/10.7326/L17-0700":[89],"SectionsAboutFull":[90],"TextPDF":[91],"ToolsAdd":[92],"to":[93,171,411,444,554],"favoritesDownload":[94],"CitationsTrack":[95],"CitationsPermissions":[96],"ShareFacebookTwitterLinkedInRedditEmail":[97],"IN":[98],"RESPONSE:The":[99],"2015":[100,184,476],"NSDUH":[101,155],"questionnaire":[102],"items":[103],"about":[104],"specific":[105,139,173],"pain":[106],"relievers":[107],"focused":[108],"exclusively":[109],"prescription":[111,140,174,538],"opioids":[112,141,304],"(1).":[113],"On":[114],"the":[115,128,146,162,167,273,300,352,359,362,370,377,383,395,406,409,413,423,428,434,440,446,455,571,595],"basis":[116],"of":[117,123,137,235,260,265,303,346,351,361,376,380,386,405,427,433,439,563,573,583,590,636],"data":[118],"from":[119],"this":[120,347],"survey,":[121],"34%":[122],"civilian,":[124],"noninstitutionalized":[125],"adults":[126,226],"United":[129,274],"States":[130,275],"reported":[131],"having":[132],"used":[133],"at":[134,142,209,461],"least":[135,143],"1":[136],"these":[138,172],"once":[144],"past":[147],"12":[148,164],"months":[149],"(Table).Table.":[150],"Specific":[151],"Prescription":[152,504],"Opioids":[153],"That":[154],"Respondents":[156],"Were":[157],"Asked":[158],"About":[159],"Using":[160],"During":[161],"Past":[163],"Months":[165],"Before":[166],"Survey":[168,186,478],"InterviewIn":[169],"addition":[170],"opioids,":[175],"...References1.":[176],"Center":[177],"for":[178,195,400,415,448],"Behavioral":[179],"Statistics":[181],"Quality.":[183],"National":[185,371,378,477],"(NSDUH):":[192],"CAI":[193],"specifications":[194],"programming.":[196],"English":[197],"version.":[198],"Substance":[199,323,363],"Administration.":[205],"February":[206],"2015.":[207],"Accessed":[208],"www.samhsa.gov/data/sites/default/files/NSDUH2015MRB/NSDUHmrbCAIquex2015.pdf":[210],"29":[212],"October":[213],"2017.":[214],"Google":[215],"Scholar2.":[216],"Saloner":[217],"B,":[218],"Bandara":[219],"SN,":[220],"McGinty":[221],"EE,":[222],"Barry":[223],"CL.":[224],"Justice-involved":[225],"with":[227,535,566],"substance":[228],"use":[229,270,592],"disorders:":[230],"coverage":[231],"increased":[232],"but":[233],"rates":[234],"treatment":[236],"did":[237],"not":[238,356],"2014.":[240],"Aff":[242],"(Millwood).":[243],"2016;35:1058-66.":[244],"[PMID:":[245,281,313],"27269023]":[246],"doi:10.1377/hlthaff.2016.0005":[247],"CrossrefMedlineGoogle":[248,284,316],"Scholar3.":[249],"Compton":[250,489],"WM,":[251],"Dawson":[252],"D,":[253],"Duffy":[254],"SQ,":[255],"Grant":[256],"BF.":[257],"The":[258,342,392,417,450],"effect":[259],"inmate":[261],"populations":[262],"estimates":[264],"DSM-IV":[266],"alcohol":[267],"drug":[269],"disorders":[271],"[Letter].":[276],"Am":[277,308],"J":[278,309],"Psychiatry.":[279],"2010;167:473-4.":[280],"20360330]":[282],"doi:10.1176/appi.ajp.2009.09081087":[283],"Scholar4.":[285],"Hwang":[286],"CS,":[287],"Kang":[288],"EM,":[289],"Kornegay":[290],"CJ,":[291],"Staffa":[292],"JA,":[293],"Jones":[294,503],"CM,":[295],"McAninch":[296],"JK.":[297],"Trends":[298],"concomitant":[301],"prescribing":[302],"benzodiazepines,":[306],"2002-2014.":[307],"Prev":[310],"Med.":[311],"2016;51:151-60.":[312],"27079639]":[314],"doi:10.1016/j.amepre.2016.02.014":[315],"Scholar":[317],"Author,":[318],"InformationAffiliations:":[322],"C.M.J.)National":[333],"C.B.)Disclaimer:":[341],"findings":[343],"conclusions":[345],"study":[348],"are":[349],"those":[350],"authors":[353],"do":[355],"necessarily":[357],"reflect":[358],"views":[360],"Institutes":[379],"Health,":[381],"Department":[385],"Human":[389],"Services.Financial":[390],"Support:":[391],"sponsors":[393,418,451],"supported":[394],"authors,":[396],"who":[397],"were":[398],"responsible":[399],"preparation,":[401],"review,":[402],"approval":[404],"manuscript":[407,414,447],"decision":[410,443],"submit":[412,445],"publication.":[416,449],"had":[419],"no":[420],"role":[421],"design":[424],"conduct":[426],"study,":[429],"analysis":[430],"interpretation":[432],"data,":[435],"preparation":[436],"review":[438],"manuscript,":[441],"or":[442],"reviewed":[452],"approved":[454],"manuscript.Disclosures:":[456],"Disclosures":[457],"can":[458],"be":[459],"viewed":[460],"www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M17-0865.":[462],"PreviousarticleNextarticle":[463],"Advertisement":[464],"FiguresReferencesRelatedDetailsSee":[465],"AlsoPrescription":[466],"Adults:":[475],"Beth":[484],"Han":[485],",":[486,490,493,496,499],"Blanco":[492],"Elizabeth":[494],"Crane":[495],"Jinhee":[497],"Lee":[498],"Adults":[513],"Jeffrey":[514],"A.":[515],"Linder":[516],"Suzanne":[518],"K.":[519],"Berman":[520],"Metrics":[521],"Cited":[522],"byDental":[523],"Prescriptions":[525,565],"Overdose":[527],"Risk":[528],"Patients":[530,546],"Their":[532],"FamiliesFactors":[533],"associated":[534],"discharge":[536],"opioid":[537,584,591],"after":[539],"hip":[540],"fracture":[541],"fixationOpioid-Limiting":[542],"Regulation:":[543],"Effect":[544],"Undergoing":[547],"Knee":[548],"Shoulder":[550],"ArthroscopyLorcaserin":[551],"maintenance":[552],"fails":[553],"attenuate":[555],"heroin":[556],"vs.":[557],"food":[558],"choice":[559],"rhesus":[561],"monkeysAssociations":[562],"Death":[567],"Hospitalization":[569],"across":[570],"Spectrum":[572],"Estimated":[574],"GFRThe":[575],"relationship":[576],"between":[577],"pupil":[578],"diameter":[579],"other":[581],"measures":[582],"withdrawal":[585],"during":[586],"naloxone":[587],"precipitated":[588],"withdrawalManagement":[589],"disorder":[593],"USA:":[596],"present":[597],"status":[598],"future":[600],"directions":[601],"6":[602,620,625],"2018Volume":[604],"168,":[605],"Issue":[606,623],"5Page:":[607],"383-384KeywordsDisclosureDrug":[608],"abuseInformation":[609],"storage":[610],"retrievalLong-term":[612],"careNursing":[613],"homesOpioidsOutpatientsPsychiatry":[614],"mental":[616],"healthQuestionnairesSubstance":[617],"abuse":[618],"ePublished:":[619],"2018":[622,627,632],"Published:":[624],"Copyright":[628],"&":[629],"PermissionsCopyright":[630],"\u00a9":[631],"by":[633],"American":[634],"College":[635],"Physicians.":[637],"All":[638],"Rights":[639],"Reserved.PDF":[640],"downloadLoading":[641],"...":[642]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-03-29T00:00:00"}