{"id":"https://openalex.org/W2789790519","doi":"https://doi.org/10.1039/c7nr09695j","title":"Stable micelles based on a mixture of coiled-coils: the role of different oligomeric states","display_name":"Stable micelles based on a mixture of coiled-coils: the role of different oligomeric states","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2789790519","doi":"https://doi.org/10.1039/c7nr09695j","mag":"2789790519","pmid":"https://pubmed.ncbi.nlm.nih.gov/29637959"},"language":"en","primary_location":{"id":"doi:10.1039/c7nr09695j","doi":"https://doi.org/10.1039/c7nr09695j","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c7nr09695j","pdf_url":null,"source":{"id":"https://openalex.org/S23181512","display_name":"Nanoscale","issn_l":"2040-3364","issn":["2040-3364","2040-3372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031623126","display_name":"Dan Ma","orcid":"https://orcid.org/0000-0001-9701-2750","observed_orcids":["https://orcid.org/0000-0001-9701-2750"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dan Ma","raw_affiliation_strings":["Department of Mechanical Engineering","Evanston","Northwestern University","USA","Department of Mechanical Engineering, Northwestern University, Evanston, Illinois 60208, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering","institution_ids":[]},{"raw_affiliation_string":"Evanston","institution_ids":[]},{"raw_affiliation_string":"Northwestern University","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"USA","institution_ids":[]},{"raw_affiliation_string":"Department of Mechanical Engineering, Northwestern University, Evanston, Illinois 60208, USA","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014744105","display_name":"Sinan Keten","orcid":"https://orcid.org/0000-0003-2203-1425","observed_orcids":["https://orcid.org/0000-0003-2203-1425"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sinan Keten","raw_affiliation_strings":["Department of Civil and Environmental Engineering","Department of Mechanical Engineering","Evanston","Northwestern University","USA","Department of Civil and Environmental Engineering, Northwestern University, Evanston, Illinois 60208, USA","Department of Mechanical Engineering, Northwestern University, Evanston, Illinois 60208, USA"],"raw_orcid":"https://orcid.org/0000-0003-2203-1425","affiliations":[{"raw_affiliation_string":"Department of Civil and Environmental Engineering","institution_ids":[]},{"raw_affiliation_string":"Department of Mechanical Engineering","institution_ids":[]},{"raw_affiliation_string":"Evanston","institution_ids":[]},{"raw_affiliation_string":"Northwestern University","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"USA","institution_ids":[]},{"raw_affiliation_string":"Department of Civil and Environmental Engineering, Northwestern University, Evanston, Illinois 60208, USA","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Department of Mechanical Engineering, Northwestern University, Evanston, Illinois 60208, USA","institution_ids":["https://openalex.org/I111979921"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5014744105"],"corresponding_institution_ids":["https://openalex.org/I111979921"],"apc_list":null,"apc_paid":null,"fwci":0.2532,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.37103205,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"10","issue":"16","first_page":"7589","last_page":"7596"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10721","display_name":"Surfactants and Colloidal Systems","score":0.7919999957084656,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10721","display_name":"Surfactants and Colloidal Systems","score":0.7919999957084656,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.08229999989271164,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.05490000173449516,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mixed-micelles","display_name":"mixed micelles","score":0.7940000295639038},{"id":"https://openalex.org/keywords/coiled-coil-peptides","display_name":"coiled-coil peptides","score":0.8220000267028809},{"id":"https://openalex.org/keywords/oligomeric-state","display_name":"oligomeric state","score":0.8569999933242798},{"id":"https://openalex.org/keywords/multivalency","display_name":"multivalency","score":0.5600000023841858},{"id":"https://openalex.org/keywords/nanophase-separation","display_name":"nanophase separation","score":0.7570000290870667},{"id":"https://openalex.org/keywords/nanodomains","display_name":"nanodomains","score":0.777999997138977},{"id":"https://openalex.org/keywords/phase-separation","display_name":"phase separation","score":0.765999972820282},{"id":"https://openalex.org/keywords/drug-delivery","display_name":"drug delivery","score":0.7089999914169312},{"id":"https://openalex.org/keywords/self-assembly","display_name":"self-assembly","score":0.6970000267028809}],"concepts":[{"id":"https://openalex.org/C11268172","wikidata":"https://www.wikidata.org/wiki/Q421110","display_name":"Micelle","level":3,"score":0.9375832080841064},{"id":"https://openalex.org/C2780263894","wikidata":"https://www.wikidata.org/wiki/Q335268","display_name":"Alkyl","level":2,"score":0.7018192410469055},{"id":"https://openalex.org/C54400483","wikidata":"https://www.wikidata.org/wiki/Q1793202","display_name":"PEG ratio","level":2,"score":0.5891190767288208},{"id":"https://openalex.org/C197336794","wikidata":"https://www.wikidata.org/wiki/Q5161150","display_name":"Conjugate","level":2,"score":0.5540423393249512},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5412625074386597},{"id":"https://openalex.org/C44280652","wikidata":"https://www.wikidata.org/wiki/Q104837","display_name":"Phase (matter)","level":2,"score":0.5325018167495728},{"id":"https://openalex.org/C2777873363","wikidata":"https://www.wikidata.org/wiki/Q13533436","display_name":"Tetra","level":2,"score":0.41307246685028076},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.41046756505966187},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3749775290489197},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.30449146032333374},{"id":"https://openalex.org/C184651966","wikidata":"https://www.wikidata.org/wiki/Q906356","display_name":"Aqueous solution","level":2,"score":0.07454222440719604},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.045176804065704346},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C10138342","wikidata":"https://www.wikidata.org/wiki/Q43015","display_name":"Finance","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D004337","descriptor_name":"Drug Carriers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008823","descriptor_name":"Micelles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011092","descriptor_name":"Polyethylene Glycols","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1039/c7nr09695j","doi":"https://doi.org/10.1039/c7nr09695j","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c7nr09695j","pdf_url":null,"source":{"id":"https://openalex.org/S23181512","display_name":"Nanoscale","issn_l":"2040-3364","issn":["2040-3364","2040-3372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"journal-article"},{"id":"pmid:29637959","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29637959","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4788385944","display_name":null,"funder_award_id":"N00014-13-1-0760","funder_id":"https://openalex.org/F4320338298","funder_display_name":"Office of Naval Research Global"}],"funders":[{"id":"https://openalex.org/F4320337345","display_name":"Office of Naval Research","ror":"https://ror.org/00rk2pe57"},{"id":"https://openalex.org/F4320338298","display_name":"Office of Naval Research Global","ror":"https://ror.org/00rk2pe57"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W1004999168","https://openalex.org/W1542159434","https://openalex.org/W1964000982","https://openalex.org/W1967578025","https://openalex.org/W1976499671","https://openalex.org/W1981608564","https://openalex.org/W1985241728","https://openalex.org/W1988771852","https://openalex.org/W1989353157","https://openalex.org/W1993338842","https://openalex.org/W1999882211","https://openalex.org/W2001018320","https://openalex.org/W2008756327","https://openalex.org/W2015054155","https://openalex.org/W2019465613","https://openalex.org/W2024181684","https://openalex.org/W2027137358","https://openalex.org/W2027408247","https://openalex.org/W2027432937","https://openalex.org/W2032655419","https://openalex.org/W2036096594","https://openalex.org/W2036278602","https://openalex.org/W2048839675","https://openalex.org/W2049172089","https://openalex.org/W2049801133","https://openalex.org/W2051016884","https://openalex.org/W2051893661","https://openalex.org/W2052757271","https://openalex.org/W2057343423","https://openalex.org/W2060116019","https://openalex.org/W2074929394","https://openalex.org/W2088659772","https://openalex.org/W2106654936","https://openalex.org/W2110447282","https://openalex.org/W2118641614","https://openalex.org/W2126818937","https://openalex.org/W2126901672","https://openalex.org/W2143468796","https://openalex.org/W2149887153","https://openalex.org/W2150981663","https://openalex.org/W2214587777","https://openalex.org/W2313863691","https://openalex.org/W2314742135","https://openalex.org/W2315456628","https://openalex.org/W2319462907","https://openalex.org/W2323737385","https://openalex.org/W2516129446","https://openalex.org/W2531029074","https://openalex.org/W2533742712","https://openalex.org/W2749672060","https://openalex.org/W3204078426","https://openalex.org/W4234094017"],"related_works":["https://openalex.org/W2749672060","https://openalex.org/W2533742712","https://openalex.org/W2544728505","https://openalex.org/W2329831693","https://openalex.org/W2315160604","https://openalex.org/W2118641614","https://openalex.org/W2587039631","https://openalex.org/W2145927652","https://openalex.org/W2029677759","https://openalex.org/W1970544135"],"abstract_inverted_index":{"Homomeric":[0],"micelles":[1,30,41,102,147],"with":[2,31,148],"tunable":[3],"size,":[4],"shape":[5],"and":[6,24,65,78,96,103,141,157],"stability":[7],"have":[8],"been":[9],"extensively":[10],"studied":[11,91],"for":[12],"biomedical":[13],"applications":[14],"such":[15],"as":[16],"drug":[17,142],"carriers.":[18],"However,":[19],"designing":[20],"the":[21,49,62,72,92,100,109,115,122,126,138,155],"local":[22],"valency":[23],"self-assembled":[25,42],"morphology":[26],"of":[27,94,137,145,159],"nanophase-separated":[28,160],"multicomponent":[29],"varied":[32],"ligand":[33],"binding":[34],"possibilities":[35],"remains":[36],"challenging.":[37],"Here,":[38],"we":[39,90],"present":[40],"from":[43,130],"amphiphilic":[44],"peptide-PEG-lipid":[45],"hybrid":[46],"conjugates,":[47],"where":[48],"peptides":[50],"can":[51,67],"be":[52,68],"either":[53],"a":[54],"3-helix":[55,95],"or":[56],"4-helix":[57,97],"coiled-coil.":[58],"We":[59,112],"demonstrate":[60],"that":[61,114],"micelle":[63],"size":[64],"sphericity":[66],"controlled":[69,149],"based":[70],"on":[71],"coiled-coil":[73,132],"oligomeric":[74,133],"state.":[75],"Using":[76],"theory":[77],"coarse-grained":[79],"dissipative":[80],"particle":[81],"dynamics":[82],"(DPD)":[83],"simulations":[84],"in":[85,125],"an":[86],"explicit":[87],"solvent":[88],"simulation,":[89],"distribution":[93],"conjugates":[98],"within":[99,108],"mixed":[101,110,146],"observed":[104],"self-organization":[105],"into":[106,154],"nanodomains":[107],"micelle.":[111],"discovered":[113],"phase":[116],"separation":[117],"behavior":[118],"is":[119],"dictated":[120],"by":[121],"geometry":[123],"mismatch":[124],"alkyl":[127],"chain":[128],"length":[129],"different":[131],"states.":[134],"Our":[135],"analyses":[136],"self-assembly":[139],"tendency":[140],"delivery":[143],"potency":[144],"multivalency":[150],"provide":[151],"important":[152],"insights":[153],"assembly":[156],"formation":[158],"micelles.":[161]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-03-29T00:00:00"}