{"id":"https://openalex.org/W2787280665","doi":"https://doi.org/10.1039/c7fo01625e","title":"Dihomo-gamma-linolenic acid induces fat loss in C. elegans in an omega-3-independent manner by promoting peroxisomal fatty acid \u03b2-oxidation","display_name":"Dihomo-gamma-linolenic acid induces fat loss in C. elegans in an omega-3-independent manner by promoting peroxisomal fatty acid \u03b2-oxidation","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2787280665","doi":"https://doi.org/10.1039/c7fo01625e","mag":"2787280665","pmid":"https://pubmed.ncbi.nlm.nih.gov/29465730"},"language":"en","primary_location":{"id":"doi:10.1039/c7fo01625e","doi":"https://doi.org/10.1039/c7fo01625e","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c7fo01625e","pdf_url":null,"source":{"id":"https://openalex.org/S2483688756","display_name":"Food & Function","issn_l":"2042-6496","issn":["2042-6496","2042-650X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food & Function","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2787280665"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084113322","display_name":"David Navarro\u2010Herrera","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I88155538","display_name":"Universidad de Navarra","ror":"https://ror.org/02rxc7m23","country_code":"ES","type":"education","lineage":["https://openalex.org/I88155538"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"David Navarro-Herrera","raw_affiliation_strings":["Department of Biochemistry and Genetics","Pamplona","School of Science","Spain","University of Navarra","University of Navarra, School of Pharmacy & Nutrition, Centre for Nutrition Research, Pamplona, Spain","University of Navarra, School of Science, Department of Biochemistry and Genetics, Pamplona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Genetics","institution_ids":[]},{"raw_affiliation_string":"Pamplona","institution_ids":[]},{"raw_affiliation_string":"School of Science","institution_ids":[]},{"raw_affiliation_string":"Spain","institution_ids":[]},{"raw_affiliation_string":"University of Navarra","institution_ids":["https://openalex.org/I88155538"]},{"raw_affiliation_string":"University of Navarra, School of Pharmacy & Nutrition, Centre for Nutrition Research, Pamplona, Spain","institution_ids":["https://openalex.org/I88155538"]},{"raw_affiliation_string":"University of Navarra, School of Science, Department of Biochemistry and Genetics, Pamplona, Spain","institution_ids":["https://openalex.org/I88155538"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050104014","display_name":"Paula Aranaz","orcid":"https://orcid.org/0000-0002-1282-0079","observed_orcids":["https://orcid.org/0000-0002-1282-0079"]},"institutions":[{"id":"https://openalex.org/I88155538","display_name":"Universidad de Navarra","ror":"https://ror.org/02rxc7m23","country_code":"ES","type":"education","lineage":["https://openalex.org/I88155538"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Paula Aranaz","raw_affiliation_strings":["Centre for Nutrition Research","Pamplona","School of Pharmacy & Nutrition","Spain","University of Navarra","University of Navarra, School of Pharmacy & Nutrition, Centre for Nutrition Research, Pamplona, Spain"],"raw_orcid":"https://orcid.org/0000-0002-1282-0079","affiliations":[{"raw_affiliation_string":"Centre for Nutrition Research","institution_ids":[]},{"raw_affiliation_string":"Pamplona","institution_ids":[]},{"raw_affiliation_string":"School of Pharmacy & Nutrition","institution_ids":[]},{"raw_affiliation_string":"Spain","institution_ids":[]},{"raw_affiliation_string":"University of Navarra","institution_ids":["https://openalex.org/I88155538"]},{"raw_affiliation_string":"University of Navarra, School of Pharmacy & Nutrition, Centre for Nutrition Research, Pamplona, Spain","institution_ids":["https://openalex.org/I88155538"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022432008","display_name":"Laura Eder\u2010Azanza","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210112085","display_name":"Navarre Institute of Health Research","ror":"https://ror.org/023d5h353","country_code":"ES","type":"education","lineage":["https://openalex.org/I4210112085"]},{"id":"https://openalex.org/I88155538","display_name":"Universidad de Navarra","ror":"https://ror.org/02rxc7m23","country_code":"ES","type":"education","lineage":["https://openalex.org/I88155538"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Laura Eder-Azanza","raw_affiliation_strings":["Department of Biochemistry and Genetics","Pamplona","School of Science","Spain","University of Navarra","Navarra Institute for Health Research (IdiSNA), Pamplona, Spain","University of Navarra, School of Science, Department of Biochemistry and Genetics, Pamplona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Genetics","institution_ids":[]},{"raw_affiliation_string":"Pamplona","institution_ids":[]},{"raw_affiliation_string":"School of Science","institution_ids":[]},{"raw_affiliation_string":"Spain","institution_ids":[]},{"raw_affiliation_string":"University of Navarra","institution_ids":["https://openalex.org/I88155538"]},{"raw_affiliation_string":"Navarra Institute for Health Research (IdiSNA), Pamplona, Spain","institution_ids":["https://openalex.org/I4210112085"]},{"raw_affiliation_string":"University of Navarra, School of Science, Department of Biochemistry and Genetics, Pamplona, Spain","institution_ids":["https://openalex.org/I88155538"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043436645","display_name":"Mar\u00eda Zabala","orcid":"https://orcid.org/0000-0002-4225-5277","observed_orcids":["https://orcid.org/0000-0002-4225-5277"]},"institutions":[{"id":"https://openalex.org/I88155538","display_name":"Universidad de Navarra","ror":"https://ror.org/02rxc7m23","country_code":"ES","type":"education","lineage":["https://openalex.org/I88155538"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Mar\u00eda Zabala","raw_affiliation_strings":["Centre for Nutrition Research","Pamplona","School of Pharmacy & Nutrition","Spain","University of Navarra","University of Navarra, School of Pharmacy & Nutrition, Centre for Nutrition Research, Pamplona, Spain"],"raw_orcid":"https://orcid.org/0000-0002-4225-5277","affiliations":[{"raw_affiliation_string":"Centre for Nutrition Research","institution_ids":[]},{"raw_affiliation_string":"Pamplona","institution_ids":[]},{"raw_affiliation_string":"School of Pharmacy & Nutrition","institution_ids":[]},{"raw_affiliation_string":"Spain","institution_ids":[]},{"raw_affiliation_string":"University of Navarra","institution_ids":["https://openalex.org/I88155538"]},{"raw_affiliation_string":"University of Navarra, School of Pharmacy & Nutrition, Centre for Nutrition Research, Pamplona, Spain","institution_ids":["https://openalex.org/I88155538"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111446689","display_name":"Cristina Hurtado","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210112085","display_name":"Navarre Institute of Health Research","ror":"https://ror.org/023d5h353","country_code":"ES","type":"education","lineage":["https://openalex.org/I4210112085"]},{"id":"https://openalex.org/I88155538","display_name":"Universidad de Navarra","ror":"https://ror.org/02rxc7m23","country_code":"ES","type":"education","lineage":["https://openalex.org/I88155538"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Cristina Hurtado","raw_affiliation_strings":["Department of Biochemistry and Genetics","Pamplona","School of Science","Spain","University of Navarra","Navarra Institute for Health Research (IdiSNA), Pamplona, Spain","University of Navarra, School of Science, Department of Biochemistry and Genetics, Pamplona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Genetics","institution_ids":[]},{"raw_affiliation_string":"Pamplona","institution_ids":[]},{"raw_affiliation_string":"School of Science","institution_ids":[]},{"raw_affiliation_string":"Spain","institution_ids":[]},{"raw_affiliation_string":"University of Navarra","institution_ids":["https://openalex.org/I88155538"]},{"raw_affiliation_string":"Navarra Institute for Health Research (IdiSNA), Pamplona, Spain","institution_ids":["https://openalex.org/I4210112085"]},{"raw_affiliation_string":"University of Navarra, School of Science, Department of Biochemistry and Genetics, Pamplona, Spain","institution_ids":["https://openalex.org/I88155538"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084593294","display_name":"Ana Romo\u2010Hualde","orcid":"https://orcid.org/0000-0001-6370-0707","observed_orcids":["https://orcid.org/0000-0001-6370-0707"]},"institutions":[{"id":"https://openalex.org/I88155538","display_name":"Universidad de Navarra","ror":"https://ror.org/02rxc7m23","country_code":"ES","type":"education","lineage":["https://openalex.org/I88155538"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Ana Romo-Hualde","raw_affiliation_strings":["Centre for Nutrition Research","Pamplona","School of Pharmacy & Nutrition","Spain","University of Navarra","University of Navarra, School of Pharmacy & Nutrition, Centre for Nutrition Research, Pamplona, Spain"],"raw_orcid":"https://orcid.org/0000-0001-6370-0707","affiliations":[{"raw_affiliation_string":"Centre for Nutrition Research","institution_ids":[]},{"raw_affiliation_string":"Pamplona","institution_ids":[]},{"raw_affiliation_string":"School of Pharmacy & Nutrition","institution_ids":[]},{"raw_affiliation_string":"Spain","institution_ids":[]},{"raw_affiliation_string":"University of Navarra","institution_ids":["https://openalex.org/I88155538"]},{"raw_affiliation_string":"University of Navarra, School of Pharmacy & Nutrition, Centre for Nutrition Research, Pamplona, Spain","institution_ids":["https://openalex.org/I88155538"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100738225","display_name":"Jos\u00e9 Alfredo Mart\u00ednez","orcid":"https://orcid.org/0000-0001-5218-6941","observed_orcids":["https://orcid.org/0000-0001-5218-6941"]},"institutions":[{"id":"https://openalex.org/I2801724371","display_name":"Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition","ror":"https://ror.org/02s65tk16","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2801724371"]},{"id":"https://openalex.org/I4210112085","display_name":"Navarre Institute of Health Research","ror":"https://ror.org/023d5h353","country_code":"ES","type":"education","lineage":["https://openalex.org/I4210112085"]},{"id":"https://openalex.org/I88155538","display_name":"Universidad de Navarra","ror":"https://ror.org/02rxc7m23","country_code":"ES","type":"education","lineage":["https://openalex.org/I88155538"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"J. Alfredo Mart\u00ednez","raw_affiliation_strings":["Centre for Nutrition Research","Pamplona","School of Pharmacy & Nutrition","Spain","University of Navarra","Navarra Institute for Health Research (IdiSNA), Pamplona, Spain","Spanish Biomedical Research Center in Physiopathology of Obesity and Nutrition (CIBERobn), Madrid, Spain","University of Navarra, School of Pharmacy & Nutrition, Centre for Nutrition Research, Pamplona, Spain"],"raw_orcid":"https://orcid.org/0000-0001-5218-6941","affiliations":[{"raw_affiliation_string":"Centre for Nutrition Research","institution_ids":[]},{"raw_affiliation_string":"Pamplona","institution_ids":[]},{"raw_affiliation_string":"School of Pharmacy & Nutrition","institution_ids":[]},{"raw_affiliation_string":"Spain","institution_ids":[]},{"raw_affiliation_string":"University of Navarra","institution_ids":["https://openalex.org/I88155538"]},{"raw_affiliation_string":"Navarra Institute for Health Research (IdiSNA), Pamplona, Spain","institution_ids":["https://openalex.org/I4210112085"]},{"raw_affiliation_string":"Spanish Biomedical Research Center in Physiopathology of Obesity and Nutrition (CIBERobn), Madrid, Spain","institution_ids":["https://openalex.org/I2801724371"]},{"raw_affiliation_string":"University of Navarra, School of Pharmacy & Nutrition, Centre for Nutrition Research, Pamplona, Spain","institution_ids":["https://openalex.org/I88155538"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070668487","display_name":"Carlos J. Gonz\u00e1lez-Navarro","orcid":"https://orcid.org/0000-0002-3517-9077","observed_orcids":["https://orcid.org/0000-0002-3517-9077"]},"institutions":[{"id":"https://openalex.org/I88155538","display_name":"Universidad de Navarra","ror":"https://ror.org/02rxc7m23","country_code":"ES","type":"education","lineage":["https://openalex.org/I88155538"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Carlos J. Gonz\u00e1lez-Navarro","raw_affiliation_strings":["Centre for Nutrition Research","Pamplona","School of Pharmacy & Nutrition","Spain","University of Navarra","University of Navarra, School of Pharmacy & Nutrition, Centre for Nutrition Research, Pamplona, Spain"],"raw_orcid":"https://orcid.org/0000-0002-3517-9077","affiliations":[{"raw_affiliation_string":"Centre for Nutrition Research","institution_ids":[]},{"raw_affiliation_string":"Pamplona","institution_ids":[]},{"raw_affiliation_string":"School of Pharmacy & Nutrition","institution_ids":[]},{"raw_affiliation_string":"Spain","institution_ids":[]},{"raw_affiliation_string":"University of Navarra","institution_ids":["https://openalex.org/I88155538"]},{"raw_affiliation_string":"University of Navarra, School of Pharmacy & Nutrition, Centre for Nutrition Research, Pamplona, Spain","institution_ids":["https://openalex.org/I88155538"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057847328","display_name":"J.L. Vizmanos","orcid":"https://orcid.org/0000-0001-7416-3679","observed_orcids":["https://orcid.org/0000-0001-7416-3679"]},"institutions":[{"id":"https://openalex.org/I4210112085","display_name":"Navarre Institute of Health Research","ror":"https://ror.org/023d5h353","country_code":"ES","type":"education","lineage":["https://openalex.org/I4210112085"]},{"id":"https://openalex.org/I88155538","display_name":"Universidad de Navarra","ror":"https://ror.org/02rxc7m23","country_code":"ES","type":"education","lineage":["https://openalex.org/I88155538"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Jos\u00e9 L. Vizmanos","raw_affiliation_strings":["Department of Biochemistry and Genetics","Pamplona","School of Science","Spain","University of Navarra","Navarra Institute for Health Research (IdiSNA), Pamplona, Spain","University of Navarra, School of Science, Department of Biochemistry and Genetics, Pamplona, Spain"],"raw_orcid":"https://orcid.org/0000-0001-7416-3679","affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Genetics","institution_ids":[]},{"raw_affiliation_string":"Pamplona","institution_ids":[]},{"raw_affiliation_string":"School of Science","institution_ids":[]},{"raw_affiliation_string":"Spain","institution_ids":[]},{"raw_affiliation_string":"University of Navarra","institution_ids":["https://openalex.org/I88155538"]},{"raw_affiliation_string":"Navarra Institute for Health Research (IdiSNA), Pamplona, Spain","institution_ids":["https://openalex.org/I4210112085"]},{"raw_affiliation_string":"University of Navarra, School of Science, Department of Biochemistry and Genetics, Pamplona, Spain","institution_ids":["https://openalex.org/I88155538"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5057847328","https://openalex.org/A5070668487"],"corresponding_institution_ids":["https://openalex.org/I4210112085","https://openalex.org/I88155538"],"apc_list":null,"apc_paid":null,"fwci":2.6103,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.87549298,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"9","issue":"3","first_page":"1621","last_page":"1637"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.018699999898672104,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dihomo-gamma-linolenic-acid","display_name":"dihomo-gamma-linolenic acid","score":0.9990000128746033},{"id":"https://openalex.org/keywords/fatty-acid-beta-oxidation","display_name":"fatty acid beta-oxidation","score":0.7269999980926514},{"id":"https://openalex.org/keywords/peroxisomes","display_name":"peroxisomes","score":0.9660000205039978},{"id":"https://openalex.org/keywords/body-fat-accumulation","display_name":"body fat accumulation","score":0.7360000014305115},{"id":"https://openalex.org/keywords/fat-loss","display_name":"fat loss","score":0.7580000162124634},{"id":"https://openalex.org/keywords/omega-6-fatty-acids","display_name":"omega-6 fatty acids","score":0.9369999766349792},{"id":"https://openalex.org/keywords/omega-3-fatty-acids","display_name":"omega-3 fatty acids","score":0.9049999713897705},{"id":"https://openalex.org/keywords/gamma-linolenic-acid","display_name":"gamma-linolenic acid","score":0.9229999780654907},{"id":"https://openalex.org/keywords/linoleic-acid","display_name":"linoleic acid","score":0.9940000176429749},{"id":"https://openalex.org/keywords/arachidonic-acid","display_name":"arachidonic acid","score":0.8600000143051147},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.9309999942779541},{"id":"https://openalex.org/keywords/caenorhabditis-elegans","display_name":"Caenorhabditis elegans","score":0.9940000176429749}],"concepts":[{"id":"https://openalex.org/C127078168","wikidata":"https://www.wikidata.org/wiki/Q138639","display_name":"Peroxisome","level":3,"score":0.7362582087516785},{"id":"https://openalex.org/C2776176469","wikidata":"https://www.wikidata.org/wiki/Q418650","display_name":"Linolenic acid","level":4,"score":0.5925795435905457},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5443893671035767},{"id":"https://openalex.org/C2779311130","wikidata":"https://www.wikidata.org/wiki/Q415885","display_name":"gamma-Linolenic acid","level":4,"score":0.5272901058197021},{"id":"https://openalex.org/C2779557605","wikidata":"https://www.wikidata.org/wiki/Q9890","display_name":"Omega","level":2,"score":0.5227620601654053},{"id":"https://openalex.org/C82714985","wikidata":"https://www.wikidata.org/wiki/Q306213","display_name":"Beta oxidation","level":3,"score":0.4924107789993286},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.49172738194465637},{"id":"https://openalex.org/C3017514745","wikidata":"https://www.wikidata.org/wiki/Q191756","display_name":"Omega 3 fatty acid","level":5,"score":0.48336261510849},{"id":"https://openalex.org/C2991733762","wikidata":"https://www.wikidata.org/wiki/Q82682","display_name":"Oxidation reduction","level":2,"score":0.45795807242393494},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.43243810534477234},{"id":"https://openalex.org/C19038510","wikidata":"https://www.wikidata.org/wiki/Q2005087","display_name":"Polyunsaturated fatty acid","level":3,"score":0.37235140800476074},{"id":"https://openalex.org/C2780809830","wikidata":"https://www.wikidata.org/wiki/Q407426","display_name":"Linoleic acid","level":3,"score":0.3477209806442261},{"id":"https://openalex.org/C2777171753","wikidata":"https://www.wikidata.org/wiki/Q423345","display_name":"Docosahexaenoic acid","level":4,"score":0.22357383370399475},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.17324844002723694},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.07345286011695862},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015126","descriptor_name":"8,11,14-Eicosatrienoic Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015525","descriptor_name":"Fatty Acids, Omega-3","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017173","descriptor_name":"Caenorhabditis elegans","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020675","descriptor_name":"Peroxisomes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D043371","descriptor_name":"Fatty Acids, Omega-6","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1039/c7fo01625e","doi":"https://doi.org/10.1039/c7fo01625e","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c7fo01625e","pdf_url":null,"source":{"id":"https://openalex.org/S2483688756","display_name":"Food & Function","issn_l":"2042-6496","issn":["2042-6496","2042-650X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food & Function","raw_type":"journal-article"},{"id":"pmid:29465730","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29465730","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food & function","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306230","display_name":"American Heart Association","ror":"https://ror.org/013kjyp64"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337901","display_name":"Office of Research Infrastructure Programs, National Institutes of Health","ror":"https://ror.org/01jdyfj45"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W137123845","https://openalex.org/W1866234920","https://openalex.org/W1919055890","https://openalex.org/W1944127002","https://openalex.org/W1980118029","https://openalex.org/W1980216636","https://openalex.org/W1981101682","https://openalex.org/W1984160651","https://openalex.org/W1986186902","https://openalex.org/W1986692180","https://openalex.org/W1991211413","https://openalex.org/W1999646405","https://openalex.org/W2004775480","https://openalex.org/W2007505836","https://openalex.org/W2012383052","https://openalex.org/W2013044873","https://openalex.org/W2026088200","https://openalex.org/W2028759338","https://openalex.org/W2030176019","https://openalex.org/W2039011321","https://openalex.org/W2050552746","https://openalex.org/W2051328153","https://openalex.org/W2056476487","https://openalex.org/W2056751633","https://openalex.org/W2059171296","https://openalex.org/W2061474095","https://openalex.org/W2068083927","https://openalex.org/W2084043096","https://openalex.org/W2084720533","https://openalex.org/W2084856509","https://openalex.org/W2097339788","https://openalex.org/W2099231952","https://openalex.org/W2099540110","https://openalex.org/W2104298398","https://openalex.org/W2123832973","https://openalex.org/W2125393297","https://openalex.org/W2132350109","https://openalex.org/W2136351174","https://openalex.org/W2141314779","https://openalex.org/W2147369819","https://openalex.org/W2148521682","https://openalex.org/W2151287971","https://openalex.org/W2152311269","https://openalex.org/W2152880021","https://openalex.org/W2154882260","https://openalex.org/W2157520090","https://openalex.org/W2163475638","https://openalex.org/W2163591544","https://openalex.org/W2253332548"],"related_works":["https://openalex.org/W2253332548","https://openalex.org/W2960648679","https://openalex.org/W4283323578","https://openalex.org/W2913284640","https://openalex.org/W3134275915","https://openalex.org/W1866234920","https://openalex.org/W2035729059","https://openalex.org/W2011511722","https://openalex.org/W2028759338"],"abstract_inverted_index":{"Bioactive":[0],"compounds,":[1],"including":[2],"some":[3],"fatty":[4,42],"acids":[5,43,58],"(FAs),":[6],"can":[7],"induce":[8],"beneficial":[9],"effects":[10,30,78],"on":[11,34],"body":[12,35],"fat-content":[13],"and":[14,40,56,76,87,137],"metabolism.":[15],"In":[16],"this":[17],"work,":[18],"we":[19],"have":[20],"used":[21],"C.":[22,51],"elegans":[23],"as":[24],"a":[25,45],"model":[26],"to":[27,80,84,131],"examine":[28],"the":[29,60,77,106,111,118,124],"of":[31,47,89,120,123,126],"several":[32],"FAs":[33,66],"fat":[36,48],"accumulation.":[37],"Both":[38],"omega-3":[39,93],"omega-6":[41,72,128],"induced":[44],"reduction":[46],"content":[49],"in":[50,71,110,135],"elegans,":[52],"with":[53],"linoleic,":[54],"gamma-linolenic":[55],"dihomo-gamma-linolenic":[57,85],"being":[59],"most":[61],"effective":[62],"ones.":[63],"These":[64,114],"three":[65],"are":[67],"sequential":[68],"metabolites":[69],"especially":[70],"PUFA":[73],"synthesis":[74],"pathway":[75],"seem":[79],"be":[81],"primarily":[82],"due":[83,130],"acid,":[86],"independent":[88],"its":[90],"transformation":[91],"into":[92],"or":[94],"arachidonic":[95],"acid.":[96],"Gene":[97],"expression":[98],"analyses":[99],"suggest":[100],"that":[101],"peroxisomal":[102],"beta":[103],"oxidation":[104],"is":[105],"main":[107],"mechanism":[108],"involved":[109],"observed":[112],"effect.":[113],"results":[115],"point":[116],"out":[117],"importance":[119],"further":[121],"analysis":[122],"activity":[125],"these":[127],"FAs,":[129],"their":[132],"potential":[133],"application":[134],"obesity":[136],"related":[138],"diseases.":[139]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2018-02-23T00:00:00"}