{"id":"https://openalex.org/W2786970068","doi":"https://doi.org/10.21037/atm.2018.01.15","title":"Variable selection in Logistic regression model with genetic algorithm","display_name":"Variable selection in Logistic regression model with genetic algorithm","publication_year":2018,"publication_date":"2018-02-01","ids":{"openalex":"https://openalex.org/W2786970068","doi":"https://doi.org/10.21037/atm.2018.01.15","mag":"2786970068","pmid":"https://pubmed.ncbi.nlm.nih.gov/29610737","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5879502"},"language":"en","primary_location":{"id":"doi:10.21037/atm.2018.01.15","doi":"https://doi.org/10.21037/atm.2018.01.15","is_oa":true,"landing_page_url":"https://doi.org/10.21037/atm.2018.01.15","pdf_url":"https://atm.amegroups.com/article/viewFile/18292/pdf","source":{"id":"https://openalex.org/S2755174949","display_name":"Annals of Translational Medicine","issn_l":"2305-5839","issn":["2305-5839","2305-5847"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310321814","host_organization_name":"AME Publishing Company","host_organization_lineage":["https://openalex.org/P4310321814"],"host_organization_lineage_names":["AME Publishing Company"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Translational Medicine","raw_type":"journal-article"},"volume":null,"type":"editorial","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://atm.amegroups.com/article/viewFile/18292/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100320372","display_name":"Zhongheng Zhang","orcid":"https://orcid.org/0000-0002-2336-5323","observed_orcids":["https://orcid.org/0000-0002-2336-5323"]},"institutions":[{"id":"https://openalex.org/I2802390878","display_name":"Sir Run Run Shaw Hospital","ror":"https://ror.org/00ka6rp58","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802390878"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhongheng Zhang","raw_affiliation_strings":["Department of Emergency Medicine, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China","institution_ids":["https://openalex.org/I2802390878","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035500744","display_name":"V\u00edctor Trevi\u00f1o","orcid":"https://orcid.org/0000-0002-7472-9844","observed_orcids":["https://orcid.org/0000-0002-7472-9844"]},"institutions":[{"id":"https://openalex.org/I98461037","display_name":"Tecnol\u00f3gico de Monterrey","ror":"https://ror.org/03ayjn504","country_code":"MX","type":"education","lineage":["https://openalex.org/I98461037"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Victor Trevino","raw_affiliation_strings":["Catedra de Bioinformatica, Escuela de Medicina, Tecnologico de Monterrey, Monterrey, Nuevo Leon, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Catedra de Bioinformatica, Escuela de Medicina, Tecnologico de Monterrey, Monterrey, Nuevo Leon, Mexico","institution_ids":["https://openalex.org/I98461037"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007653799","display_name":"Sayed Shahabuddin Hoseini","orcid":"https://orcid.org/0000-0001-9940-4571","observed_orcids":["https://orcid.org/0000-0001-9940-4571"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sayed Shahabuddin Hoseini","raw_affiliation_strings":["Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062598192","display_name":"Smaranda Belciug","orcid":"https://orcid.org/0000-0003-2950-3501","observed_orcids":["https://orcid.org/0000-0003-2950-3501"]},"institutions":[{"id":"https://openalex.org/I97553796","display_name":"University of Craiova","ror":"https://ror.org/03s251g81","country_code":"RO","type":"education","lineage":["https://openalex.org/I97553796"]}],"countries":["RO"],"is_corresponding":false,"raw_author_name":"Smaranda Belciug","raw_affiliation_strings":["Department of Computer Science, Faculty of Sciences, University of Craiova, Craiova, Romania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Faculty of Sciences, University of Craiova, Craiova, Romania","institution_ids":["https://openalex.org/I97553796"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064919574","display_name":"A. Manivanna Boopathi","orcid":"https://orcid.org/0000-0002-9996-6723","observed_orcids":["https://orcid.org/0000-0002-9996-6723"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Arumugam Manivanna Boopathi","raw_affiliation_strings":["Department of Electrical and Electronics Engineering, Ariyalur Engineering College, Ariyalur, Tamilnadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronics Engineering, Ariyalur Engineering College, Ariyalur, Tamilnadu, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059001271","display_name":"Ping Zhang","orcid":"https://orcid.org/0000-0002-3907-1127","observed_orcids":["https://orcid.org/0000-0002-3907-1127"]},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Ping Zhang","raw_affiliation_strings":["Menzies Health Institute Queensland, Griffith University, Brisbane, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Menzies Health Institute Queensland, Griffith University, Brisbane, Australia","institution_ids":["https://openalex.org/I11701301"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036876854","display_name":"Florin Gorunescu","orcid":"https://orcid.org/0000-0001-6826-2785","observed_orcids":["https://orcid.org/0000-0001-6826-2785"]},"institutions":[{"id":"https://openalex.org/I185286233","display_name":"University of Pitesti","ror":"https://ror.org/058b16x44","country_code":"RO","type":"education","lineage":["https://openalex.org/I185286233"]},{"id":"https://openalex.org/I28109999","display_name":"University of Medicine and Pharmacy of Craiova","ror":"https://ror.org/031d5vw30","country_code":"RO","type":"education","lineage":["https://openalex.org/I28109999"]}],"countries":["RO"],"is_corresponding":false,"raw_author_name":"Florin Gorunescu","raw_affiliation_strings":["Department of Mathematics and Computer Science, University of Pite\u015fti, Pite\u015fti, Romania","Department of Mathematics, Biostatistics and Informatics, University of Medicine and Pharmacy of Craiova, Craiova, Romania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mathematics and Computer Science, University of Pite\u015fti, Pite\u015fti, Romania","institution_ids":["https://openalex.org/I185286233"]},{"raw_affiliation_string":"Department of Mathematics, Biostatistics and Informatics, University of Medicine and Pharmacy of Craiova, Craiova, Romania","institution_ids":["https://openalex.org/I28109999"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003911324","display_name":"Subha Velappan","orcid":"https://orcid.org/0000-0002-4992-4090","observed_orcids":["https://orcid.org/0000-0002-4992-4090"]},"institutions":[{"id":"https://openalex.org/I182997119","display_name":"Manonmaniam Sundaranar University","ror":"https://ror.org/02qgw5c67","country_code":"IN","type":"education","lineage":["https://openalex.org/I182997119"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Velappan Subha","raw_affiliation_strings":["Department of Computer Science and Engineering, Manonmaniam Sundaranar University, Tirunelveli, Tamilnadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, Manonmaniam Sundaranar University, Tirunelveli, Tamilnadu, India","institution_ids":["https://openalex.org/I182997119"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013943783","display_name":"Songshi Dai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802390878","display_name":"Sir Run Run Shaw Hospital","ror":"https://ror.org/00ka6rp58","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802390878"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Songshi Dai","raw_affiliation_strings":["College of Electrical Engineering, Zhejiang University, Hangzhou 310027, China","Hangzhou mAIcim Co. Ltd., Hangzhou 310058, China","Department of Emergency Medicine, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Electrical Engineering, Zhejiang University, Hangzhou 310027, China","institution_ids":["https://openalex.org/I76130692"]},{"raw_affiliation_string":"Hangzhou mAIcim Co. Ltd., Hangzhou 310058, China","institution_ids":[]},{"raw_affiliation_string":"Department of Emergency Medicine, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China","institution_ids":["https://openalex.org/I2802390878","https://openalex.org/I76130692"]}]}],"institutions":[],"countries_distinct_count":6,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5100320372"],"corresponding_institution_ids":["https://openalex.org/I2802390878","https://openalex.org/I76130692"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":46,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"6","issue":"3","first_page":"45","last_page":"45"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10136","display_name":"Statistical Methods and Inference","score":0.95169997215271,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10136","display_name":"Statistical Methods and Inference","score":0.95169997215271,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11396","display_name":"Artificial Intelligence in Healthcare","score":0.014600000344216824,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10100","display_name":"Metaheuristic Optimization Algorithms Research","score":0.006399999838322401,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/feature-selection","display_name":"feature selection","score":0.9990000128746033},{"id":"https://openalex.org/keywords/logistic-regression","display_name":"logistic regression","score":0.9089999794960022},{"id":"https://openalex.org/keywords/genetic-algorithm","display_name":"genetic algorithm","score":0.9480000138282776},{"id":"https://openalex.org/keywords/stepwise-selection","display_name":"stepwise selection","score":0.6570000052452087},{"id":"https://openalex.org/keywords/best-subset-selection","display_name":"best subset selection","score":0.9890000224113464},{"id":"https://openalex.org/keywords/local-optima","display_name":"local optima","score":0.9079999923706055},{"id":"https://openalex.org/keywords/clinical-decision-making","display_name":"clinical decision-making","score":0.5519999861717224},{"id":"https://openalex.org/keywords/biomedical-data","display_name":"biomedical data","score":0.7149999737739563},{"id":"https://openalex.org/keywords/model-specification","display_name":"model specification","score":0.4659999907016754}],"concepts":[{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.8096272349357605},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6766501665115356},{"id":"https://openalex.org/C182365436","wikidata":"https://www.wikidata.org/wiki/Q50701","display_name":"Variable (mathematics)","level":2,"score":0.6207545399665833},{"id":"https://openalex.org/C119043178","wikidata":"https://www.wikidata.org/wiki/Q320723","display_name":"Covariate","level":2,"score":0.5757005214691162},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.5655508637428284},{"id":"https://openalex.org/C173801870","wikidata":"https://www.wikidata.org/wiki/Q201413","display_name":"Heuristic","level":2,"score":0.5271149277687073},{"id":"https://openalex.org/C34736171","wikidata":"https://www.wikidata.org/wiki/Q918333","display_name":"Preprocessor","level":2,"score":0.47914546728134155},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4728013873100281},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.4537546634674072},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.44846591353416443},{"id":"https://openalex.org/C127705205","wikidata":"https://www.wikidata.org/wiki/Q5748245","display_name":"Heuristics","level":2,"score":0.4340873658657074},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.4333553910255432},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3754658102989197},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.17804858088493347},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.21037/atm.2018.01.15","doi":"https://doi.org/10.21037/atm.2018.01.15","is_oa":true,"landing_page_url":"https://doi.org/10.21037/atm.2018.01.15","pdf_url":"https://atm.amegroups.com/article/viewFile/18292/pdf","source":{"id":"https://openalex.org/S2755174949","display_name":"Annals of Translational Medicine","issn_l":"2305-5839","issn":["2305-5839","2305-5847"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310321814","host_organization_name":"AME Publishing Company","host_organization_lineage":["https://openalex.org/P4310321814"],"host_organization_lineage_names":["AME Publishing Company"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Translational Medicine","raw_type":"journal-article"},{"id":"pmid:29610737","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29610737","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of translational medicine","raw_type":"Editorial"},{"id":"pmh:oai:pubmedcentral.nih.gov:5879502","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5879502/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ann Transl Med","raw_type":"Text"},{"id":"pmh:oai:research-repository.griffith.edu.au:10072/388319","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10072/388319","pdf_url":null,"source":{"id":"https://openalex.org/S7407064376","display_name":"Griffith Research Online","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal article"}],"best_oa_location":{"id":"doi:10.21037/atm.2018.01.15","doi":"https://doi.org/10.21037/atm.2018.01.15","is_oa":true,"landing_page_url":"https://doi.org/10.21037/atm.2018.01.15","pdf_url":"https://atm.amegroups.com/article/viewFile/18292/pdf","source":{"id":"https://openalex.org/S2755174949","display_name":"Annals of Translational Medicine","issn_l":"2305-5839","issn":["2305-5839","2305-5847"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310321814","host_organization_name":"AME Publishing Company","host_organization_lineage":["https://openalex.org/P4310321814"],"host_organization_lineage_names":["AME Publishing Company"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Translational Medicine","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320338464","display_name":"Natural Science Foundation of Zhejiang Province","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2786970068.pdf","grobid_xml":"https://content.openalex.org/works/W2786970068.grobid-xml"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W49513413","https://openalex.org/W117863929","https://openalex.org/W126720219","https://openalex.org/W1972000232","https://openalex.org/W1992414896","https://openalex.org/W2006617902","https://openalex.org/W2012132549","https://openalex.org/W2031539400","https://openalex.org/W2076877989","https://openalex.org/W2154687435","https://openalex.org/W2219829573","https://openalex.org/W2339573327","https://openalex.org/W2492513888","https://openalex.org/W2534302245","https://openalex.org/W2598931168"],"related_works":["https://openalex.org/W2895426983","https://openalex.org/W3119115620","https://openalex.org/W4311077470","https://openalex.org/W117863929","https://openalex.org/W1599735551","https://openalex.org/W1757714862","https://openalex.org/W2144351957","https://openalex.org/W4253825301","https://openalex.org/W6958358671","https://openalex.org/W126720219"],"abstract_inverted_index":{"Variable":[0],"or":[1,98],"feature":[2],"selection":[3,43,85,200],"is":[4,35,86,113,122,141,180],"one":[5],"of":[6,18,24,47,70,83,103,111,137,177,217],"the":[7,16,21,41,45,49,54,68,71,75,81,118,126,144,160,166,181,215,227],"most":[8,50],"important":[9,90],"steps":[10],"in":[11,15,56,74,129,150,183,201,219,226],"model":[12],"specification.":[13],"Especially":[14],"case":[17,182],"medical-decision":[19],"making,":[20],"direct":[22],"use":[23,216],"a":[25,29,60,211],"medical":[26],"database,":[27],"without":[28,114],"previous":[30],"analysis":[31,237],"and":[32,91,194,232],"preprocessing":[33],"step,":[34],"often":[36],"counterproductive.":[37],"In":[38,78],"this":[39],"way,":[40],"variable":[42,84,107,128,199,220],"represents":[44],"method":[46],"choosing":[48],"relevant":[51],"attributes":[52],"from":[53],"database":[55],"order":[57],"to":[58,66,87,175,209,214,234],"build":[59],"robust":[61],"learning":[62],"models":[63,72],"and,":[64],"thus,":[65],"improve":[67],"performance":[69],"used":[73,197],"decision":[76],"process.":[77],"biomedical":[79],"research,":[80],"purpose":[82],"select":[88],"clinically":[89],"statistically":[92],"significant":[93],"variables,":[94,178],"while":[95],"excluding":[96],"unrelated":[97],"noise":[99],"variables.":[100,138],"A":[101],"variety":[102],"methods":[104],"exist":[105],"for":[106,198],"selection,":[108],"but":[109,165],"none":[110],"them":[112],"limitations.":[115],"For":[116],"example,":[117],"stepwise":[119],"approach,":[120],"which":[121,179],"highly":[123],"used,":[124],"adds":[125],"best":[127,154],"each":[130],"cycle":[131],"generally":[132],"producing":[133],"an":[134],"acceptable":[135],"set":[136],"Nevertheless,":[139],"it":[140,147],"limited":[142],"by":[143],"fact":[145],"that":[146],"commonly":[148],"trapped":[149],"local":[151],"optima.":[152],"The":[153,222],"subset":[155],"approach":[156,213],"can":[157,169,195,229],"systematically":[158],"search":[159],"entire":[161],"covariate":[162],"pattern":[163],"space,":[164],"solution":[167],"pool":[168],"be":[170,196,230],"extremely":[171],"large":[172],"with":[173],"tens":[174],"hundreds":[176],"nowadays":[184],"clinical":[185],"data.":[186],"Genetic":[187],"algorithms":[188],"(GA)":[189],"are":[190],"heuristic":[191],"optimization":[192],"approaches":[193],"multivariable":[202],"regression":[203],"models.":[204],"This":[205],"tutorial":[206],"paper":[207],"aims":[208],"provide":[210],"step-by-step":[212],"GA":[218],"selection.":[221],"R":[223],"code":[224],"provided":[225],"text":[228],"extended":[231],"adapted":[233],"other":[235],"data":[236],"needs.":[238]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":12},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2018-02-23T00:00:00"}