{"id":"https://openalex.org/W2786217567","doi":null,"title":"Transcriptional Regulation of the First Cell Fate Decision.","display_name":"Transcriptional Regulation of the First Cell Fate Decision.","publication_year":2017,"publication_date":"2017-01-01","ids":{"openalex":"https://openalex.org/W2786217567","mag":"2786217567","pmid":"https://pubmed.ncbi.nlm.nih.gov/29658952","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5897107"},"language":"en","primary_location":{"id":"pmid:29658952","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29658952","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of developmental biology & regenerative medicine","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC5897107","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077254397","display_name":"Catherine Rhee","orcid":"https://orcid.org/0000-0002-1613-1975","observed_orcids":["https://orcid.org/0000-0002-1613-1975"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I86519309","display_name":"The University of Texas at Austin","ror":"https://ror.org/00hj54h04","country_code":"US","type":"education","lineage":["https://openalex.org/I86519309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Catherine Rhee","raw_affiliation_strings":["Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA","Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, 78712, USA","Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge MA 02138, USA","Dept. of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA","institution_ids":["https://openalex.org/I86519309"]},{"raw_affiliation_string":"Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, 78712, USA","institution_ids":["https://openalex.org/I86519309"]},{"raw_affiliation_string":"Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge MA 02138, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Dept. of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA","institution_ids":["https://openalex.org/I86519309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100767723","display_name":"Jonghwan Kim","orcid":"https://orcid.org/0000-0002-9919-9843","observed_orcids":["https://orcid.org/0000-0002-9919-9843"]},"institutions":[{"id":"https://openalex.org/I86519309","display_name":"The University of Texas at Austin","ror":"https://ror.org/00hj54h04","country_code":"US","type":"education","lineage":["https://openalex.org/I86519309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonghwan Kim","raw_affiliation_strings":["Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA","Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, 78712, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA","institution_ids":["https://openalex.org/I86519309"]},{"raw_affiliation_string":"Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, 78712, USA","institution_ids":["https://openalex.org/I86519309"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064892746","display_name":"Haley O. Tucker","orcid":"https://orcid.org/0000-0001-7735-2862","observed_orcids":["https://orcid.org/0000-0001-7735-2862"]},"institutions":[{"id":"https://openalex.org/I86519309","display_name":"The University of Texas at Austin","ror":"https://ror.org/00hj54h04","country_code":"US","type":"education","lineage":["https://openalex.org/I86519309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Haley O Tucker","raw_affiliation_strings":["Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA","Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, 78712, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA","institution_ids":["https://openalex.org/I86519309"]},{"raw_affiliation_string":"Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, 78712, USA","institution_ids":["https://openalex.org/I86519309"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0974,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.3992441,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"1","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.9535999894142151,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.9535999894142151,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.032600000500679016,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transcriptional-regulation","display_name":"transcriptional regulation","score":0.9829999804496765},{"id":"https://openalex.org/keywords/cell-fate-determination","display_name":"cell fate determination","score":0.8080000281333923},{"id":"https://openalex.org/keywords/trophectoderm","display_name":"trophectoderm","score":0.9139999747276306},{"id":"https://openalex.org/keywords/early-embryo","display_name":"early embryo","score":0.3659999966621399},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.44200000166893005}],"concepts":[{"id":"https://openalex.org/C75059768","wikidata":"https://www.wikidata.org/wiki/Q519516","display_name":"Epiblast","level":5,"score":0.8646053075790405},{"id":"https://openalex.org/C77255625","wikidata":"https://www.wikidata.org/wiki/Q402093","display_name":"Reprogramming","level":3,"score":0.8109991550445557},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.7653073072433472},{"id":"https://openalex.org/C159399396","wikidata":"https://www.wikidata.org/wiki/Q1335221","display_name":"Inner cell mass","level":5,"score":0.764691948890686},{"id":"https://openalex.org/C163952510","wikidata":"https://www.wikidata.org/wiki/Q5058196","display_name":"Cell fate determination","level":4,"score":0.6736295819282532},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6732147336006165},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6341849565505981},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.6270129680633545},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.6002672910690308},{"id":"https://openalex.org/C2777495146","wikidata":"https://www.wikidata.org/wiki/Q1889778","display_name":"Trophoblast","level":5,"score":0.5516440272331238},{"id":"https://openalex.org/C148738053","wikidata":"https://www.wikidata.org/wiki/Q210861","display_name":"Cellular differentiation","level":3,"score":0.4588502049446106},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.346666157245636},{"id":"https://openalex.org/C2778177303","wikidata":"https://www.wikidata.org/wiki/Q227717","display_name":"Blastocyst","level":4,"score":0.33382275700569153},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.3329635262489319},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.24228599667549133},{"id":"https://openalex.org/C87073359","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryogenesis","level":3,"score":0.20767197012901306},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1621498167514801},{"id":"https://openalex.org/C129536746","wikidata":"https://www.wikidata.org/wiki/Q1141026","display_name":"Gastrulation","level":4,"score":0.12189656496047974},{"id":"https://openalex.org/C2776953305","wikidata":"https://www.wikidata.org/wiki/Q1212935","display_name":"Placenta","level":4,"score":0.05454370379447937},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.0},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"pmid:29658952","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29658952","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of developmental biology & regenerative medicine","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:4826947","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5897107","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5897107","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5897107/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Dev Biol Regen Med","raw_type":"Text"},{"id":"mag:2786217567","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29658952","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:4826947","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5897107","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G681228638","display_name":"Investigating regulators controlling differentiation potential of ES cells","funder_award_id":"R01GM112722","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G7666326434","display_name":"MAR Mediated Control of The IgH Enhancer","funder_award_id":"R01CA031534","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":134,"referenced_works":["https://openalex.org/W1514520124","https://openalex.org/W1547855212","https://openalex.org/W1603534654","https://openalex.org/W1608762409","https://openalex.org/W1845629080","https://openalex.org/W1888777832","https://openalex.org/W1956465114","https://openalex.org/W1963559963","https://openalex.org/W1965181820","https://openalex.org/W1965411245","https://openalex.org/W1965428318","https://openalex.org/W1968062255","https://openalex.org/W1968931043","https://openalex.org/W1970508192","https://openalex.org/W1971451591","https://openalex.org/W1971582979","https://openalex.org/W1975751233","https://openalex.org/W1978798972","https://openalex.org/W1979298412","https://openalex.org/W1981088384","https://openalex.org/W1987902909","https://openalex.org/W1988294855","https://openalex.org/W1994115491","https://openalex.org/W1994144105","https://openalex.org/W1996048984","https://openalex.org/W2001849513","https://openalex.org/W2002451729","https://openalex.org/W2004102023","https://openalex.org/W2004777871","https://openalex.org/W2004989087","https://openalex.org/W2006499356","https://openalex.org/W2007497552","https://openalex.org/W2007634751","https://openalex.org/W2008244502","https://openalex.org/W2010188939","https://openalex.org/W2012305943","https://openalex.org/W2013205740","https://openalex.org/W2013438278","https://openalex.org/W2017230855","https://openalex.org/W2019209906","https://openalex.org/W2027071899","https://openalex.org/W2027134492","https://openalex.org/W2031333605","https://openalex.org/W2032512845","https://openalex.org/W2032942434","https://openalex.org/W2033843363","https://openalex.org/W2035087026","https://openalex.org/W2041825762","https://openalex.org/W2042754794","https://openalex.org/W2045740132","https://openalex.org/W2045857127","https://openalex.org/W2045899482","https://openalex.org/W2045985937","https://openalex.org/W2049652727","https://openalex.org/W2050563880","https://openalex.org/W2052820766","https://openalex.org/W2052988833","https://openalex.org/W2053482584","https://openalex.org/W2053860318","https://openalex.org/W2056089399","https://openalex.org/W2058972167","https://openalex.org/W2061004792","https://openalex.org/W2062691001","https://openalex.org/W2067423804","https://openalex.org/W2068478010","https://openalex.org/W2070613990","https://openalex.org/W2070700342","https://openalex.org/W2073157961","https://openalex.org/W2073286325","https://openalex.org/W2077765163","https://openalex.org/W2078154411","https://openalex.org/W2079421773","https://openalex.org/W2080342872","https://openalex.org/W2084421599","https://openalex.org/W2086943348","https://openalex.org/W2089228715","https://openalex.org/W2090935343","https://openalex.org/W2092099264","https://openalex.org/W2095293920","https://openalex.org/W2095417588","https://openalex.org/W2096011465","https://openalex.org/W2096736856","https://openalex.org/W2102687261","https://openalex.org/W2102912143","https://openalex.org/W2105469909","https://openalex.org/W2107575419","https://openalex.org/W2110015307","https://openalex.org/W2110737932","https://openalex.org/W2112785261","https://openalex.org/W2113823919","https://openalex.org/W2120060263","https://openalex.org/W2121995585","https://openalex.org/W2122097157","https://openalex.org/W2122864540","https://openalex.org/W2123829995","https://openalex.org/W2125987139","https://openalex.org/W2126851387","https://openalex.org/W2127311430","https://openalex.org/W2127431151","https://openalex.org/W2128718933","https://openalex.org/W2128940002","https://openalex.org/W2129957319","https://openalex.org/W2131098671","https://openalex.org/W2131586796","https://openalex.org/W2132069716","https://openalex.org/W2138417516","https://openalex.org/W2141898188","https://openalex.org/W2142330433","https://openalex.org/W2143232449","https://openalex.org/W2146606376","https://openalex.org/W2147441917","https://openalex.org/W2148272837","https://openalex.org/W2150163104","https://openalex.org/W2153725532","https://openalex.org/W2156444072","https://openalex.org/W2159584345","https://openalex.org/W2159733516","https://openalex.org/W2159747138","https://openalex.org/W2160431003","https://openalex.org/W2161090637","https://openalex.org/W2162439237","https://openalex.org/W2162641053","https://openalex.org/W2164384065","https://openalex.org/W2166185239","https://openalex.org/W2167202160","https://openalex.org/W2169529166","https://openalex.org/W2170614891","https://openalex.org/W2176310740","https://openalex.org/W2519280707","https://openalex.org/W2520991658","https://openalex.org/W2559881236","https://openalex.org/W2742879842","https://openalex.org/W6999320546","https://openalex.org/W7097749369"],"related_works":["https://openalex.org/W2315451355","https://openalex.org/W1982303453","https://openalex.org/W2731698311","https://openalex.org/W2062691001","https://openalex.org/W2990329401","https://openalex.org/W2003951674","https://openalex.org/W3197632581","https://openalex.org/W2090261213","https://openalex.org/W7058585641","https://openalex.org/W3005968137"],"abstract_inverted_index":{"equivalent":[0],"of":[1],"the":[2],"trophectoderm.":[3]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2018-02-23T00:00:00"}
