{"id":"https://openalex.org/W2783366764","doi":"https://doi.org/10.1039/c7an01837a","title":"A three-dimensional electrochemical paper-based analytical device for low-cost diagnostics","display_name":"A three-dimensional electrochemical paper-based analytical device for low-cost diagnostics","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2783366764","doi":"https://doi.org/10.1039/c7an01837a","mag":"2783366764","pmid":"https://pubmed.ncbi.nlm.nih.gov/29410987"},"language":"en","primary_location":{"id":"doi:10.1039/c7an01837a","doi":"https://doi.org/10.1039/c7an01837a","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c7an01837a","pdf_url":null,"source":{"id":"https://openalex.org/S105746325","display_name":"The Analyst","issn_l":"0003-2654","issn":["0003-2654","1364-5528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Analyst","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040387526","display_name":"Meera Punjiya","orcid":"https://orcid.org/0000-0002-9719-5451","observed_orcids":["https://orcid.org/0000-0002-9719-5451"]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Meera Punjiya","raw_affiliation_strings":["Medford","Tufts University","USA","Tufts University, Medford, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-9719-5451","affiliations":[{"raw_affiliation_string":"Medford","institution_ids":[]},{"raw_affiliation_string":"Tufts University","institution_ids":["https://openalex.org/I121934306"]},{"raw_affiliation_string":"USA","institution_ids":[]},{"raw_affiliation_string":"Tufts University, Medford, MA, USA","institution_ids":["https://openalex.org/I121934306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051481054","display_name":"Chung Hee Moon","orcid":"https://orcid.org/0000-0002-3652-0214","observed_orcids":["https://orcid.org/0000-0002-3652-0214"]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chung Hee Moon","raw_affiliation_strings":["Medford","Tufts University","USA","Tufts University, Medford, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medford","institution_ids":[]},{"raw_affiliation_string":"Tufts University","institution_ids":["https://openalex.org/I121934306"]},{"raw_affiliation_string":"USA","institution_ids":[]},{"raw_affiliation_string":"Tufts University, Medford, MA, USA","institution_ids":["https://openalex.org/I121934306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037645067","display_name":"Zimple Matharu","orcid":"https://orcid.org/0000-0002-2324-9883","observed_orcids":["https://orcid.org/0000-0002-2324-9883"]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zimple Matharu","raw_affiliation_strings":["Medford","Tufts University","USA","Tufts University, Medford, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medford","institution_ids":[]},{"raw_affiliation_string":"Tufts University","institution_ids":["https://openalex.org/I121934306"]},{"raw_affiliation_string":"USA","institution_ids":[]},{"raw_affiliation_string":"Tufts University, Medford, MA, USA","institution_ids":["https://openalex.org/I121934306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022468802","display_name":"Hojatollah Rezaei Nejad","orcid":"https://orcid.org/0000-0002-4384-3476","observed_orcids":["https://orcid.org/0000-0002-4384-3476"]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hojatollah Rezaei Nejad","raw_affiliation_strings":["Medford","Tufts University","USA","Tufts University, Medford, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-4384-3476","affiliations":[{"raw_affiliation_string":"Medford","institution_ids":[]},{"raw_affiliation_string":"Tufts University","institution_ids":["https://openalex.org/I121934306"]},{"raw_affiliation_string":"USA","institution_ids":[]},{"raw_affiliation_string":"Tufts University, Medford, MA, USA","institution_ids":["https://openalex.org/I121934306"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088891429","display_name":"Sameer Sonkusale","orcid":"https://orcid.org/0000-0003-3579-910X","observed_orcids":["https://orcid.org/0000-0003-3579-910X"]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sameer Sonkusale","raw_affiliation_strings":["Medford","Tufts University","USA","Tufts University, Medford, MA, USA"],"raw_orcid":"https://orcid.org/0000-0003-3579-910X","affiliations":[{"raw_affiliation_string":"Medford","institution_ids":[]},{"raw_affiliation_string":"Tufts University","institution_ids":["https://openalex.org/I121934306"]},{"raw_affiliation_string":"USA","institution_ids":[]},{"raw_affiliation_string":"Tufts University, Medford, MA, USA","institution_ids":["https://openalex.org/I121934306"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5088891429"],"corresponding_institution_ids":["https://openalex.org/I121934306"],"apc_list":null,"apc_paid":null,"fwci":1.9464,"has_fulltext":false,"cited_by_count":43,"citation_normalized_percentile":{"value":0.84651926,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"143","issue":"5","first_page":"1059","last_page":"1064"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.8720999956130981,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.8720999956130981,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.11680000275373459,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/paper-based-analytical-devices","display_name":"paper-based analytical devices","score":0.859000027179718},{"id":"https://openalex.org/keywords/screen-printed-electrodes","display_name":"screen-printed electrodes","score":0.9240000247955322},{"id":"https://openalex.org/keywords/electrochemical-sensing","display_name":"electrochemical sensing","score":0.7620000243186951},{"id":"https://openalex.org/keywords/point-of-care-testing","display_name":"point-of-care testing","score":0.9869999885559082},{"id":"https://openalex.org/keywords/wax-printing","display_name":"wax printing","score":0.7879999876022339},{"id":"https://openalex.org/keywords/glucose-detection","display_name":"glucose detection","score":0.5260000228881836},{"id":"https://openalex.org/keywords/dopamine-sensing","display_name":"dopamine sensing","score":0.859000027179718},{"id":"https://openalex.org/keywords/ph-sensing","display_name":"pH sensing","score":0.9789999723434448},{"id":"https://openalex.org/keywords/voltammetry","display_name":"voltammetry","score":0.6460000276565552},{"id":"https://openalex.org/keywords/amperometry","display_name":"amperometry","score":0.9610000252723694},{"id":"https://openalex.org/keywords/potentiometry","display_name":"potentiometry","score":0.9290000200271606},{"id":"https://openalex.org/keywords/low-cost-sensors","display_name":"low-cost sensors","score":0.49300000071525574}],"concepts":[{"id":"https://openalex.org/C52859227","wikidata":"https://www.wikidata.org/wiki/Q7877","display_name":"Electrochemistry","level":3,"score":0.5790122151374817},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.38604238629341125},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.37686455249786377},{"id":"https://openalex.org/C113196181","wikidata":"https://www.wikidata.org/wiki/Q485223","display_name":"Analytical Chemistry (journal)","level":2,"score":0.37023696303367615},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.30621737241744995},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.2117455005645752},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.14681550860404968},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.06019550561904907}],"mesh":[{"descriptor_ui":"D004298","descriptor_name":"Dopamine","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005947","descriptor_name":"Glucose","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010209","descriptor_name":"Paper","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011327","descriptor_name":"Printing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D046210","descriptor_name":"Microfluidic Analytical Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055664","descriptor_name":"Electrochemical Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056656","descriptor_name":"Lab-On-A-Chip Devices","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1039/c7an01837a","doi":"https://doi.org/10.1039/c7an01837a","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c7an01837a","pdf_url":null,"source":{"id":"https://openalex.org/S105746325","display_name":"The Analyst","issn_l":"0003-2654","issn":["0003-2654","1364-5528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Analyst","raw_type":"journal-article"},{"id":"pmid:29410987","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29410987","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Analyst","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G861978243","display_name":"Creating Future Female Engineering Leaders","funder_award_id":"1444926","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W632789555","https://openalex.org/W1964711538","https://openalex.org/W1974713769","https://openalex.org/W1979694794","https://openalex.org/W1989157562","https://openalex.org/W2010659423","https://openalex.org/W2036635684","https://openalex.org/W2039469634","https://openalex.org/W2050456578","https://openalex.org/W2068896164","https://openalex.org/W2087224951","https://openalex.org/W2113558416","https://openalex.org/W2120340503","https://openalex.org/W2120968628","https://openalex.org/W2125557502","https://openalex.org/W2152020702","https://openalex.org/W2161907344","https://openalex.org/W2321756610","https://openalex.org/W2327731128","https://openalex.org/W2460780005","https://openalex.org/W2489179305","https://openalex.org/W2493629413","https://openalex.org/W2607231491","https://openalex.org/W4254720078"],"related_works":["https://openalex.org/W2507703239","https://openalex.org/W2044399599","https://openalex.org/W3006845704","https://openalex.org/W2979647744","https://openalex.org/W2536071503","https://openalex.org/W2074148430","https://openalex.org/W2113558416","https://openalex.org/W3166916080","https://openalex.org/W4399054724","https://openalex.org/W3024852069"],"abstract_inverted_index":{"Paper-based":[0],"microfluidic":[1],"devices":[2,22],"with":[3,33,65,140,179],"screen-printed":[4],"electrodes":[5],"(SPEs)":[6],"for":[7,12,73,95,125,129,191],"electrochemical":[8,136],"sensing":[9,18,84],"are":[10,106],"popular":[11],"low-cost":[13],"point-of-care":[14,192],"diagnostics.":[15],"The":[16,86,152,175],"electroactive":[17,46,83],"area":[19,47],"in":[20,31,44,99],"these":[21],"is":[23,30,157],"always":[24],"the":[25,34,38,82,93,123,130,155],"irregular,":[26],"bottom-SPE":[27],"surface":[28,80],"which":[29,48,71],"contact":[32],"analyte":[35],"flowing":[36],"within":[37],"paper":[39],"substrate.":[40],"Unfortunately,":[41],"this":[42,56,89],"results":[43],"an":[45,135],"varies":[49],"widely":[50],"from":[51],"sensor":[52,156],"to":[53],"sensor.":[54],"In":[55],"paper,":[57],"we":[58,133],"present":[59],"a":[60,66,76,109,118,141,149,180,185],"three-dimensional":[61],"paper-based":[62,137],"analytical":[63,138],"device":[64,139],"hollow":[67],"3D":[68,176],"fluid":[69],"reservoir":[70,91],"allows":[72],"use":[74,87],"of":[75,88,111,154,165],"more":[77],"uniform":[78],"top-SPE":[79],"as":[81,148,170],"area.":[85],"isolated":[90],"eliminates":[92],"need":[94,124],"dielectric":[96],"inks":[97],"used":[98],"conventional":[100],"SPEs":[101],"on":[102],"paper.":[103],"Our":[104],"sensors":[105],"fabricated":[107],"using":[108],"combination":[110],"wax-printing,":[112],"screen-printing":[113],"and":[114,162,173],"simple":[115],"folding":[116],"via":[117],"cleanroom":[119],"free":[120],"process":[121],"without":[122],"expensive":[126],"equipment.":[127],"Additionally,":[128],"first":[131],"time,":[132],"demonstrate":[134],"custom":[142,181],"designed":[143],"potentiostat":[144,183],"integrated":[145],"circuit":[146],"(IC)":[147],"miniaturized":[150],"reader.":[151],"versatility":[153],"demonstrated":[158],"through":[159],"voltammetric,":[160],"amperometric":[161],"potentiometric":[163],"measurements":[164],"important":[166],"biochemical":[167],"analytes":[168],"such":[169],"dopamine,":[171],"glucose":[172],"pH.":[174],"ePAD":[177],"together":[178],"CMOS":[182],"demonstrates":[184],"low-cost,":[186],"versatile,":[187],"self-contained":[188],"system":[189],"suitable":[190],"diagnostic":[193],"devices.":[194]},"counts_by_year":[{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-01-26T00:00:00"}