{"id":"https://openalex.org/W2783263160","doi":"https://doi.org/10.1097/gox.0000000000001623","title":"Earfold Implantable Clip System for Correction of Prominent Ears: Analysis of Safety in 403 Patients","display_name":"Earfold Implantable Clip System for Correction of Prominent Ears: Analysis of Safety in 403 Patients","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2783263160","doi":"https://doi.org/10.1097/gox.0000000000001623","mag":"2783263160","pmid":"https://pubmed.ncbi.nlm.nih.gov/29464160","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5811290"},"language":"en","primary_location":{"id":"doi:10.1097/gox.0000000000001623","doi":"https://doi.org/10.1097/gox.0000000000001623","is_oa":true,"landing_page_url":"https://doi.org/10.1097/gox.0000000000001623","pdf_url":null,"source":{"id":"https://openalex.org/S2754281505","display_name":"Plastic & Reconstructive Surgery Global Open","issn_l":"2169-7574","issn":["2169-7574"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plastic and Reconstructive Surgery - Global Open","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1097/gox.0000000000001623","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038950584","display_name":"Norbert Kang","orcid":"https://orcid.org/0000-0002-9343-8487","observed_orcids":["https://orcid.org/0000-0002-9343-8487","https://orcid.org/0000-0003-0730-9695"]},"institutions":[{"id":"https://openalex.org/I2801138448","display_name":"The Royal Free Hospital","ror":"https://ror.org/01ge67z96","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I169248724","https://openalex.org/I2801138448"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Norbert V. Kang","raw_affiliation_strings":["Glumicic Medical Group, Zagreb, Croatia","Royal Free Hospital NHS Trust, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glumicic Medical Group, Zagreb, Croatia","institution_ids":[]},{"raw_affiliation_string":"Royal Free Hospital NHS Trust, London, United Kingdom","institution_ids":["https://openalex.org/I2801138448"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025871481","display_name":"Nilesh M. Sojitra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801138448","display_name":"The Royal Free Hospital","ror":"https://ror.org/01ge67z96","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I169248724","https://openalex.org/I2801138448"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Nilesh Sojitra","raw_affiliation_strings":["Glumicic Medical Group, Zagreb, Croatia","Royal Free Hospital NHS Trust, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glumicic Medical Group, Zagreb, Croatia","institution_ids":[]},{"raw_affiliation_string":"Royal Free Hospital NHS Trust, London, United Kingdom","institution_ids":["https://openalex.org/I2801138448"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038137903","display_name":"Sinisa Glumicic","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sinisa Glumicic","raw_affiliation_strings":["Glumicic Medical Group, Zagreb, Croatia","Selston Cosmetic Clinic, Nottinghamshire, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glumicic Medical Group, Zagreb, Croatia","institution_ids":[]},{"raw_affiliation_string":"Selston Cosmetic Clinic, Nottinghamshire, United Kingdom","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055624504","display_name":"Jacobus A. Vlok","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jacobus A. Vlok","raw_affiliation_strings":["Glumicic Medical Group, Zagreb, Croatia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glumicic Medical Group, Zagreb, Croatia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010025652","display_name":"Greg O\u2019Toole","orcid":"https://orcid.org/0000-0003-2543-4780","observed_orcids":["https://orcid.org/0000-0003-2543-4780"]},"institutions":[{"id":"https://openalex.org/I2801138448","display_name":"The Royal Free Hospital","ror":"https://ror.org/01ge67z96","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I169248724","https://openalex.org/I2801138448"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Greg O\u2019Toole","raw_affiliation_strings":["Glumicic Medical Group, Zagreb, Croatia","Royal Free Hospital NHS Trust, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glumicic Medical Group, Zagreb, Croatia","institution_ids":[]},{"raw_affiliation_string":"Royal Free Hospital NHS Trust, London, United Kingdom","institution_ids":["https://openalex.org/I2801138448"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112195712","display_name":"Saiful Alam Hannan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801138448","display_name":"The Royal Free Hospital","ror":"https://ror.org/01ge67z96","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I169248724","https://openalex.org/I2801138448"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"S. Alam Hannan","raw_affiliation_strings":["Glumicic Medical Group, Zagreb, Croatia","Royal Free Hospital NHS Trust, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glumicic Medical Group, Zagreb, Croatia","institution_ids":[]},{"raw_affiliation_string":"Royal Free Hospital NHS Trust, London, United Kingdom","institution_ids":["https://openalex.org/I2801138448"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110092278","display_name":"Walid Sabbagh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801138448","display_name":"The Royal Free Hospital","ror":"https://ror.org/01ge67z96","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I169248724","https://openalex.org/I2801138448"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Walid Sabbagh","raw_affiliation_strings":["Glumicic Medical Group, Zagreb, Croatia","Royal Free Hospital NHS Trust, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glumicic Medical Group, Zagreb, Croatia","institution_ids":[]},{"raw_affiliation_string":"Royal Free Hospital NHS Trust, London, United Kingdom","institution_ids":["https://openalex.org/I2801138448"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5010025652","https://openalex.org/A5025871481","https://openalex.org/A5038950584","https://openalex.org/A5110092278","https://openalex.org/A5112195712"],"corresponding_institution_ids":["https://openalex.org/I2801138448"],"apc_list":{"value":2195,"currency":"USD","value_usd":2195},"apc_paid":{"value":2195,"currency":"USD","value_usd":2195},"fwci":1.0319,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.74180461,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"6","issue":"1","first_page":"e1623","last_page":"e1623"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11866","display_name":"Reconstructive Facial Surgery Techniques","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11866","display_name":"Reconstructive Facial Surgery Techniques","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11812","display_name":"Nasal Surgery and Airway Studies","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13738","display_name":"Congenital Ear and Nasal Anomalies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prominent-ears","display_name":"prominent ears","score":0.6800000071525574},{"id":"https://openalex.org/keywords/otoplasty","display_name":"otoplasty","score":0.9760000109672546},{"id":"https://openalex.org/keywords/implant-safety","display_name":"implant safety","score":0.7429999709129333},{"id":"https://openalex.org/keywords/adverse-events","display_name":"adverse events","score":0.9229999780654907},{"id":"https://openalex.org/keywords/implant-revision","display_name":"implant revision","score":0.8090000152587891},{"id":"https://openalex.org/keywords/implant-extrusion","display_name":"implant extrusion","score":0.6290000081062317},{"id":"https://openalex.org/keywords/skin-erosion","display_name":"skin erosion","score":0.6299999952316284},{"id":"https://openalex.org/keywords/infection","display_name":"infection","score":0.4729999899864197}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8308779001235962},{"id":"https://openalex.org/C2781411149","wikidata":"https://www.wikidata.org/wiki/Q486975","display_name":"Implant","level":2,"score":0.8051480054855347},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.7061623334884644},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.6055719256401062},{"id":"https://openalex.org/C2779662492","wikidata":"https://www.wikidata.org/wiki/Q468787","display_name":"Hematoma","level":2,"score":0.4832902252674103},{"id":"https://openalex.org/C2776957806","wikidata":"https://www.wikidata.org/wiki/Q4895105","display_name":"Interim","level":2,"score":0.4452786445617676},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11186465620994568},{"id":"https://openalex.org/C95457728","wikidata":"https://www.wikidata.org/wiki/Q309","display_name":"History","level":0,"score":0.0},{"id":"https://openalex.org/C166957645","wikidata":"https://www.wikidata.org/wiki/Q23498","display_name":"Archaeology","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1097/gox.0000000000001623","doi":"https://doi.org/10.1097/gox.0000000000001623","is_oa":true,"landing_page_url":"https://doi.org/10.1097/gox.0000000000001623","pdf_url":null,"source":{"id":"https://openalex.org/S2754281505","display_name":"Plastic & Reconstructive Surgery Global Open","issn_l":"2169-7574","issn":["2169-7574"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plastic and Reconstructive Surgery - Global Open","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5811290","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5811290","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plast Reconstr Surg Glob Open","raw_type":"Text"},{"id":"pmid:29464160","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29464160","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plastic and reconstructive surgery. Global open","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:ff104fee132844f18c59595c4379703c","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/ff104fee132844f18c59595c4379703c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Plastic and Reconstructive Surgery, Global Open, Vol 6, Iss 1, p e1623 (2018)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1097/gox.0000000000001623","doi":"https://doi.org/10.1097/gox.0000000000001623","is_oa":true,"landing_page_url":"https://doi.org/10.1097/gox.0000000000001623","pdf_url":null,"source":{"id":"https://openalex.org/S2754281505","display_name":"Plastic & Reconstructive Surgery Global Open","issn_l":"2169-7574","issn":["2169-7574"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plastic and Reconstructive Surgery - Global Open","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332585","display_name":"Allergan","ror":"https://ror.org/00wthd003"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W73846741","https://openalex.org/W1990700484","https://openalex.org/W2005444244","https://openalex.org/W2061063832","https://openalex.org/W2072526986","https://openalex.org/W2168248719","https://openalex.org/W2170792348","https://openalex.org/W2200140147","https://openalex.org/W2327387966","https://openalex.org/W4242737857"],"related_works":["https://openalex.org/W2200140147","https://openalex.org/W3014412999","https://openalex.org/W2977331161","https://openalex.org/W4404582304","https://openalex.org/W2883528265","https://openalex.org/W2286501208","https://openalex.org/W6927074297","https://openalex.org/W3156508456","https://openalex.org/W2147866270","https://openalex.org/W3215549286"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1],"Earfold":[2,18,21,51,81,182,234],"system,":[3],"a":[4,41,114,197],"new":[5],"treatment":[6],"for":[7,46,70,113],"the":[8,17,20,24,50,68,92,95,151,240],"correction":[9,185],"of":[10,14,38,43,130,165,200,233],"prominent":[11,47,183],"ears,":[12],"consists":[13],"3":[15],"components:":[16],"implant,":[19],"introducer,":[22],"and":[23,56,67,157],"Prefold":[25],"positioner.":[26],"METHODS:":[27],"This":[28,176],"is":[29,74,187,227],"an":[30,35],"interim":[31,177],"report":[32],"based":[33,62],"on":[34,63],"ongoing":[36],"analysis":[37,178],"safety":[39],"in":[40,238],"series":[42],"patients":[44,86,109,201],"treated":[45],"ears":[48],"with":[49,189,230],"implant":[52,71,97,136,146,152,204,207],"between":[53],"February":[54],"2013":[55],"September":[57],"2014.":[58],"Safety":[59],"was":[60],"assessed":[61],"adverse":[64,170,192,213,241],"event":[65,242],"reports":[66],"need":[69],"revision;":[72],"follow-up":[73,115],"ongoing.":[75],"RESULTS:":[76],"Seven":[77],"surgeons":[78,236],"used":[79],"1,200":[80],"implants":[82],"to":[83,103,145,217],"treat":[84],"403":[85,131],"(ages,":[87],"7-70":[88],"years;":[89],"63%":[90],"male);":[91],"time":[93],"since":[94],"initial":[96],"procedure":[98],"now":[99],"ranges":[100],"from":[101],"30":[102],"48":[104],"months.":[105],"To":[106],"date,":[107],"145":[108],"(36%)":[110],"have":[111,127],"returned":[112],"visit":[116],"(mean,":[117],"7.7":[118],"months":[119],"[range,":[120],"1-34":[121],"months]).":[122],"Adverse":[123],"events":[124,193,214],"requiring":[125],"intervention":[126],"affected":[128],"39":[129],"(9.7%)":[132],"patients;":[133],"these":[134],"include":[135],"revisions":[137],"(n":[138,153,159],"=":[139,154,160],"17":[140],"[4.2%],":[141],"most":[142],"often":[143],"due":[144],"visibility),":[147],"skin":[148],"erosion":[149],"over":[150],"15":[155],"[3.7%]),":[156],"infection":[158],"7":[161],"[1.7%]).":[162],"Bleeding,":[163],"recurrence":[164],"prominence,":[166],"hematoma,":[167],"deformity,":[168],"or":[169,206,221],"scarring":[171],"did":[172],"not":[173],"occur.":[174],"CONCLUSIONS:":[175],"has":[179],"shown":[180],"that":[181,194,209,229],"ear":[184],"system":[186],"associated":[188],"relatively":[190],"few":[191],"require":[195],"intervention;":[196],"small":[198],"number":[199],"experienced":[202,237],"infection,":[203],"extrusion,":[205],"visibility":[208],"required":[210],"revision.":[211],"Most":[212],"were":[215],"related":[216],"either":[218],"patient":[219],"selection":[220],"technical":[222],"errors":[223],"at":[224],"implantation.":[225],"It":[226],"expected":[228],"continued":[231],"use":[232],"by":[235],"otoplasty,":[239],"incidence":[243],"will":[244],"decrease.":[245]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-01-26T00:00:00"}