{"id":"https://openalex.org/W2783077965","doi":"https://doi.org/10.3389/fphys.2017.01133","title":"Additive Neuroprotective Effect of Borneol with Mesenchymal Stem Cells on Ischemic Stroke in Mice","display_name":"Additive Neuroprotective Effect of Borneol with Mesenchymal Stem Cells on Ischemic Stroke in Mice","publication_year":2018,"publication_date":"2018-01-16","ids":{"openalex":"https://openalex.org/W2783077965","doi":"https://doi.org/10.3389/fphys.2017.01133","mag":"2783077965","pmid":"https://pubmed.ncbi.nlm.nih.gov/29387017","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5776113"},"language":"en","primary_location":{"id":"doi:10.3389/fphys.2017.01133","doi":"https://doi.org/10.3389/fphys.2017.01133","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fphys.2017.01133","pdf_url":"https://www.frontiersin.org/articles/10.3389/fphys.2017.01133/pdf","source":{"id":"https://openalex.org/S52732750","display_name":"Frontiers in Physiology","issn_l":"1664-042X","issn":["1664-042X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Physiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fphys.2017.01133/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100408505","display_name":"Xiaoguang Zhang","orcid":"https://orcid.org/0000-0002-4636-792X","observed_orcids":["https://orcid.org/0000-0002-4636-792X"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210099512","display_name":"Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University","ror":"https://ror.org/0156rhd17","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099512"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiao-Guang Zhang","raw_affiliation_strings":["Department of Internal Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China","Translational Center for Stem Cell Research, Tongji Hospital, Stem Cell Research Center, Tongji University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China","institution_ids":["https://openalex.org/I4210099512"]},{"raw_affiliation_string":"Translational Center for Stem Cell Research, Tongji Hospital, Stem Cell Research Center, Tongji University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I116953780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065199687","display_name":"Chang Shan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chang Shan","raw_affiliation_strings":["Department of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Rui-jin Hospital, Shanghai Jiao-tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Rui-jin Hospital, Shanghai Jiao-tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100611174","display_name":"Jiazhen Zhu","orcid":"https://orcid.org/0000-0002-5788-0841","observed_orcids":["https://orcid.org/0000-0002-5788-0841"]},"institutions":[{"id":"https://openalex.org/I4210099512","display_name":"Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University","ror":"https://ror.org/0156rhd17","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099512"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jia-Zhen Zhu","raw_affiliation_strings":["Department of Internal Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China","institution_ids":["https://openalex.org/I4210099512"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083171531","display_name":"Xiaoyi Bao","orcid":"https://orcid.org/0000-0002-1305-6965","observed_orcids":["https://orcid.org/0000-0002-1305-6965"]},"institutions":[{"id":"https://openalex.org/I4210099512","display_name":"Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University","ror":"https://ror.org/0156rhd17","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099512"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiao-Yi Bao","raw_affiliation_strings":["Department of Internal Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China","institution_ids":["https://openalex.org/I4210099512"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006277785","display_name":"Qiang Tong","orcid":"https://orcid.org/0000-0003-4881-7733","observed_orcids":["https://orcid.org/0000-0003-4881-7733"]},"institutions":[{"id":"https://openalex.org/I4210099512","display_name":"Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University","ror":"https://ror.org/0156rhd17","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099512"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiang Tong","raw_affiliation_strings":["Department of Internal Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China","institution_ids":["https://openalex.org/I4210099512"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000368520","display_name":"Xi-fan Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xi-Fan Wu","raw_affiliation_strings":["Translational Center for Stem Cell Research, Tongji Hospital, Stem Cell Research Center, Tongji University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Translational Center for Stem Cell Research, Tongji Hospital, Stem Cell Research Center, Tongji University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I116953780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101796665","display_name":"Xiaochen Tang","orcid":"https://orcid.org/0000-0001-9895-6067","observed_orcids":["https://orcid.org/0000-0001-9895-6067"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiao-Chen Tang","raw_affiliation_strings":["Translational Center for Stem Cell Research, Tongji Hospital, Stem Cell Research Center, Tongji University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Translational Center for Stem Cell Research, Tongji Hospital, Stem Cell Research Center, Tongji University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I116953780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059605597","display_name":"Ting Xue","orcid":"https://orcid.org/0000-0003-0727-9158","observed_orcids":["https://orcid.org/0000-0003-0727-9158"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ting Xue","raw_affiliation_strings":["Translational Center for Stem Cell Research, Tongji Hospital, Stem Cell Research Center, Tongji University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Translational Center for Stem Cell Research, Tongji Hospital, Stem Cell Research Center, Tongji University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I116953780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100454161","display_name":"Jie Liu","orcid":"https://orcid.org/0000-0002-9504-0587","observed_orcids":["https://orcid.org/0000-0002-9504-0587"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jie Liu","raw_affiliation_strings":["Translational Center for Stem Cell Research, Tongji Hospital, Stem Cell Research Center, Tongji University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Translational Center for Stem Cell Research, Tongji Hospital, Stem Cell Research Center, Tongji University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I116953780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022500520","display_name":"Guo\u2010qing Zheng","orcid":"https://orcid.org/0000-0001-5286-5696","observed_orcids":["https://orcid.org/0000-0001-5286-5696"]},"institutions":[{"id":"https://openalex.org/I4210099512","display_name":"Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University","ror":"https://ror.org/0156rhd17","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099512"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Guo-Qing Zheng","raw_affiliation_strings":["Department of Internal Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China","institution_ids":["https://openalex.org/I4210099512"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100322535","display_name":"Yan Wang","orcid":"https://orcid.org/0000-0001-8601-9121","observed_orcids":["https://orcid.org/0000-0001-8601-9121"]},"institutions":[{"id":"https://openalex.org/I4210099512","display_name":"Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University","ror":"https://ror.org/0156rhd17","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099512"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yan Wang","raw_affiliation_strings":["Department of Internal Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China","institution_ids":["https://openalex.org/I4210099512"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5022500520","https://openalex.org/A5100322535","https://openalex.org/A5100454161"],"corresponding_institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210099512"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":2.0858,"has_fulltext":true,"cited_by_count":27,"citation_normalized_percentile":{"value":0.86142643,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"8","issue":null,"first_page":"1133","last_page":"1133"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.5005000233650208,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.5005000233650208,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13796","display_name":"Neuroprotection in Cerebral Ischemia","score":0.37700000405311584,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.025299999862909317,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/borneol","display_name":"borneol","score":0.9980000257492065},{"id":"https://openalex.org/keywords/mesenchymal-stem-cells","display_name":"mesenchymal stem cells","score":0.9900000095367432},{"id":"https://openalex.org/keywords/ischemic-stroke","display_name":"ischemic stroke","score":0.9570000171661377},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.9150000214576721},{"id":"https://openalex.org/keywords/middle-cerebral-artery-occlusion","display_name":"middle cerebral artery occlusion","score":0.8799999952316284},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.5920000076293945},{"id":"https://openalex.org/keywords/neurogenesis","display_name":"neurogenesis","score":0.777999997138977},{"id":"https://openalex.org/keywords/infarct-size","display_name":"infarct size","score":0.8600000143051147},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.8809999823570251},{"id":"https://openalex.org/keywords/functional-recovery","display_name":"functional recovery","score":0.6980000138282776},{"id":"https://openalex.org/keywords/stem-cell-transplantation","display_name":"stem cell transplantation","score":0.6069999933242798}],"concepts":[{"id":"https://openalex.org/C2777964474","wikidata":"https://www.wikidata.org/wiki/Q412435","display_name":"Borneol","level":4,"score":0.9102013111114502},{"id":"https://openalex.org/C25498285","wikidata":"https://www.wikidata.org/wiki/Q1981368","display_name":"Neuroprotection","level":2,"score":0.8756026029586792},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.7106600999832153},{"id":"https://openalex.org/C4746552","wikidata":"https://www.wikidata.org/wiki/Q1456827","display_name":"Neurogenesis","level":2,"score":0.6378797292709351},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6212157607078552},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5063837766647339},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.4236985743045807},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3219625949859619},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.19880899786949158},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16853317618370056},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.161695659160614},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.15004315972328186},{"id":"https://openalex.org/C188947578","wikidata":"https://www.wikidata.org/wiki/Q200253","display_name":"Traditional Chinese medicine","level":3,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fphys.2017.01133","doi":"https://doi.org/10.3389/fphys.2017.01133","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fphys.2017.01133","pdf_url":"https://www.frontiersin.org/articles/10.3389/fphys.2017.01133/pdf","source":{"id":"https://openalex.org/S52732750","display_name":"Frontiers in Physiology","issn_l":"1664-042X","issn":["1664-042X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Physiology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5776113","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5776113","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Physiol","raw_type":"Text"},{"id":"pmid:29387017","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29387017","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in physiology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:019521dd4b85444eb9adabc3d6208089","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/019521dd4b85444eb9adabc3d6208089","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Physiology, Vol 8 (2018)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fphys.2017.01133","doi":"https://doi.org/10.3389/fphys.2017.01133","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fphys.2017.01133","pdf_url":"https://www.frontiersin.org/articles/10.3389/fphys.2017.01133/pdf","source":{"id":"https://openalex.org/S52732750","display_name":"Frontiers in Physiology","issn_l":"1664-042X","issn":["1664-042X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Physiology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2172667840","display_name":null,"funder_award_id":"81573750","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6599365865","display_name":null,"funder_award_id":"81371328","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8742006608","display_name":null,"funder_award_id":"2013277","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8955832736","display_name":null,"funder_award_id":"81473491","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2783077965.pdf","grobid_xml":"https://content.openalex.org/works/W2783077965.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W1807496144","https://openalex.org/W1972391714","https://openalex.org/W1976983937","https://openalex.org/W1978817477","https://openalex.org/W1990242139","https://openalex.org/W1991663943","https://openalex.org/W1993845966","https://openalex.org/W1996243257","https://openalex.org/W2014632350","https://openalex.org/W2017017011","https://openalex.org/W2025082561","https://openalex.org/W2029584195","https://openalex.org/W2038118534","https://openalex.org/W2051755309","https://openalex.org/W2052097860","https://openalex.org/W2058549869","https://openalex.org/W2059092049","https://openalex.org/W2081797313","https://openalex.org/W2084330594","https://openalex.org/W2085652502","https://openalex.org/W2094032990","https://openalex.org/W2095605434","https://openalex.org/W2112505121","https://openalex.org/W2121567769","https://openalex.org/W2140005424","https://openalex.org/W2144126123","https://openalex.org/W2165393084","https://openalex.org/W2170166094","https://openalex.org/W2177412633","https://openalex.org/W2298789981","https://openalex.org/W2335534790","https://openalex.org/W2462601649","https://openalex.org/W2529288709","https://openalex.org/W3135571977"],"related_works":["https://openalex.org/W3157515622","https://openalex.org/W2378893667","https://openalex.org/W2387325126","https://openalex.org/W1963951658","https://openalex.org/W2062271595","https://openalex.org/W2745018647","https://openalex.org/W2537880094","https://openalex.org/W2388577652","https://openalex.org/W2998752449","https://openalex.org/W2102129021"],"abstract_inverted_index":{"Intravenous":[0],"stem":[1,62,120],"cell":[2,78,97],"transplantation":[3],"initiates":[4],"neuroprotection":[5],"related":[6],"to":[7,26,40],"the":[8,54,57,103,130,136],"secretion":[9],"of":[10,86,108,117,133],"trophic":[11],"factor.":[12],"Borneol,":[13],"a":[14,20],"potential":[15],"herbal":[16],"neuroprotective":[17,32,124],"agent,":[18],"is":[19],"penetration":[21,139],"enhancer.":[22],"Here,":[23],"we":[24],"aimed":[25],"investigate":[27],"whether":[28],"they":[29],"have":[30],"additive":[31,123],"effect":[33,125,132],"on":[34,126,135],"cerebral":[35,48,127],"ischemia.":[36,128],"Borneol":[37],"was":[38],"given":[39],"mice":[41,58],"by":[42],"gavage":[43],"3":[44],"days":[45],"before":[46],"middle":[47],"artery":[49],"occlusion":[50],"(MCAO)":[51],"induction":[52],"until":[53],"day":[55],"when":[56],"were":[59,65,82],"sacrificed.":[60],"Mesenchymal":[61],"cells":[63,121],"(MSCs)":[64],"intravenously":[66],"injected":[67],"at":[68],"24":[69],"h":[70],"after":[71],"MCAO":[72],"induction.":[73],"Neurological":[74],"deficits,":[75],"infarct":[76],"volume,":[77],"death,":[79],"and":[80,88,96,101,119],"neurogenesis":[81],"evaluated.":[83],"Combined":[84],"use":[85,116],"MSCs":[87,109],"borneol":[89,118,134],"could":[90],"more":[91],"effectively":[92],"reduce":[93],"infarction":[94],"volume":[95],"apoptosis,":[98],"enhance":[99],"neurogenesis,":[100],"improve":[102],"functional":[104],"recovery":[105],"than":[106],"that":[107,114],"alone.":[110],"The":[111],"findings":[112],"showed":[113],"combined":[115],"provided":[122],"However,":[129],"supposed":[131],"improved":[137],"MSC":[138],"still":[140],"needs":[141],"further":[142],"direct":[143],"evidence.":[144]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-01-26T00:00:00"}