{"id":"https://openalex.org/W27810290","doi":"https://doi.org/10.7888/juoeh.32.317","title":"Psoriasis and Other Th17-Mediated Skin Diseases","display_name":"Psoriasis and Other Th17-Mediated Skin Diseases","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W27810290","doi":"https://doi.org/10.7888/juoeh.32.317","mag":"27810290","pmid":"https://pubmed.ncbi.nlm.nih.gov/21226422"},"language":"en","primary_location":{"id":"doi:10.7888/juoeh.32.317","doi":"https://doi.org/10.7888/juoeh.32.317","is_oa":true,"landing_page_url":"https://doi.org/10.7888/juoeh.32.317","pdf_url":"https://www.jstage.jst.go.jp/article/juoeh/32/4/32_KJ00006772460/_pdf","source":{"id":"https://openalex.org/S2754427771","display_name":"Journal of UOEH","issn_l":"0387-821X","issn":["0387-821X","2187-2864"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","medline","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313152","host_organization_name":"University of Occupational and Environmental Health Japan","host_organization_lineage":["https://openalex.org/P4310313152"],"host_organization_lineage_names":["University of Occupational and Environmental Health Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of UOEH","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/juoeh/32/4/32_KJ00006772460/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043652685","display_name":"YOSHIKI TOKURA","orcid":"https://orcid.org/0000-0001-7452-6919","observed_orcids":["https://orcid.org/0000-0001-7452-6919"]},"institutions":[{"id":"https://openalex.org/I188700360","display_name":"University of Occupational and Environmental Health Japan","ror":"https://ror.org/020p3h829","country_code":"JP","type":"education","lineage":["https://openalex.org/I188700360"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshiki TOKURA","raw_affiliation_strings":["Department of Dermatology, School of Medicine, University of Occupational and Environmental Health","Department of Dermatology, School of Medicine University of Occupational and Environmental Health Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, School of Medicine, University of Occupational and Environmental Health","institution_ids":["https://openalex.org/I188700360"]},{"raw_affiliation_string":"Department of Dermatology, School of Medicine University of Occupational and Environmental Health Japan","institution_ids":["https://openalex.org/I188700360"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090248004","display_name":"Tomoko Mori","orcid":"https://orcid.org/0000-0001-8308-7890","observed_orcids":["https://orcid.org/0000-0001-8308-7890"]},"institutions":[{"id":"https://openalex.org/I188700360","display_name":"University of Occupational and Environmental Health Japan","ror":"https://ror.org/020p3h829","country_code":"JP","type":"education","lineage":["https://openalex.org/I188700360"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomoko MORI","raw_affiliation_strings":["Department of Dermatology, School of Medicine, University of Occupational and Environmental Health"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, School of Medicine, University of Occupational and Environmental Health","institution_ids":["https://openalex.org/I188700360"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111562971","display_name":"Ryosuke Hino","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I188700360","display_name":"University of Occupational and Environmental Health Japan","ror":"https://ror.org/020p3h829","country_code":"JP","type":"education","lineage":["https://openalex.org/I188700360"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ryosuke HINO","raw_affiliation_strings":["Department of Dermatology, School of Medicine, University of Occupational and Environmental Health"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, School of Medicine, University of Occupational and Environmental Health","institution_ids":["https://openalex.org/I188700360"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I188700360"],"apc_list":null,"apc_paid":null,"fwci":2.9559,"has_fulltext":true,"cited_by_count":73,"citation_normalized_percentile":{"value":0.91135611,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"32","issue":"4","first_page":"317","last_page":"328"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10837","display_name":"Dermatology and Skin Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/psoriasis","display_name":"psoriasis","score":0.847000002861023},{"id":"https://openalex.org/keywords/th17-cells","display_name":"Th17 cells","score":0.9990000128746033},{"id":"https://openalex.org/keywords/il-17","display_name":"IL-17","score":0.9169999957084656},{"id":"https://openalex.org/keywords/il-22","display_name":"IL-22","score":0.9950000047683716},{"id":"https://openalex.org/keywords/il-23","display_name":"IL-23","score":0.9520000219345093},{"id":"https://openalex.org/keywords/keratinocyte-proliferation","display_name":"keratinocyte proliferation","score":0.878000020980835},{"id":"https://openalex.org/keywords/stat3-activation","display_name":"STAT3 activation","score":0.7440000176429749},{"id":"https://openalex.org/keywords/interleukin-8","display_name":"interleukin-8","score":0.7979999780654907},{"id":"https://openalex.org/keywords/antimicrobial-peptides","display_name":"antimicrobial peptides","score":0.9919999837875366},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9459999799728394},{"id":"https://openalex.org/keywords/tnf-alpha-receptor-antagonist","display_name":"TNF-alpha receptor antagonist","score":0.5249999761581421},{"id":"https://openalex.org/keywords/biological-therapy","display_name":"biologic therapy","score":0.824999988079071},{"id":"https://openalex.org/keywords/atopic-dermatitis","display_name":"atopic dermatitis","score":0.9760000109672546},{"id":"https://openalex.org/keywords/drug-induced-skin-reaction","display_name":"drug-induced skin reaction","score":0.9070000052452087},{"id":"https://openalex.org/keywords/acute-generalized-exanthematous-pustulosis","display_name":"acute generalized exanthematous pustulosis","score":0.9549999833106995}],"concepts":[{"id":"https://openalex.org/C2780564577","wikidata":"https://www.wikidata.org/wiki/Q179945","display_name":"Psoriasis","level":2,"score":0.6732721924781799},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.6212781667709351},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6167681217193604},{"id":"https://openalex.org/C47348012","wikidata":"https://www.wikidata.org/wiki/Q99486570","display_name":"Interleukin 17","level":3,"score":0.551633894443512},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.5309481024742126},{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.5216322541236877},{"id":"https://openalex.org/C128240485","wikidata":"https://www.wikidata.org/wiki/Q786998","display_name":"Autocrine signalling","level":3,"score":0.5080761909484863},{"id":"https://openalex.org/C171958077","wikidata":"https://www.wikidata.org/wiki/Q419333","display_name":"STAT protein","level":4,"score":0.4673998951911926},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.4384698271751404},{"id":"https://openalex.org/C2777074287","wikidata":"https://www.wikidata.org/wiki/Q1473931","display_name":"Keratinocyte","level":3,"score":0.4265609383583069},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4116537868976593},{"id":"https://openalex.org/C2778923194","wikidata":"https://www.wikidata.org/wiki/Q14912019","display_name":"STAT3","level":3,"score":0.3606080114841461},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3417288064956665},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.3392074406147003},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.25901156663894653},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.23340913653373718},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.09311690926551819},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.06076422333717346},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000097043","descriptor_name":"Interleukin-22","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001327","descriptor_name":"Autoimmune Diseases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003713","descriptor_name":"Dendritic Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003875","descriptor_name":"Drug Eruptions","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D003876","descriptor_name":"Dermatitis, Atopic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007378","descriptor_name":"Interleukins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D007378","descriptor_name":"Interleukins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011565","descriptor_name":"Psoriasis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015603","descriptor_name":"Keratinocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016209","descriptor_name":"Interleukin-8","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D018123","descriptor_name":"Receptors, Interleukin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019898","descriptor_name":"Autocrine Communication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020381","descriptor_name":"Interleukin-17","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D020381","descriptor_name":"Interleukin-17","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D023181","descriptor_name":"Antimicrobial Cationic Peptides","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D050796","descriptor_name":"STAT3 Transcription Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D052247","descriptor_name":"Nitric Oxide Synthase Type II","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D053759","descriptor_name":"Interleukin-23","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D058504","descriptor_name":"Th17 Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.7888/juoeh.32.317","doi":"https://doi.org/10.7888/juoeh.32.317","is_oa":true,"landing_page_url":"https://doi.org/10.7888/juoeh.32.317","pdf_url":"https://www.jstage.jst.go.jp/article/juoeh/32/4/32_KJ00006772460/_pdf","source":{"id":"https://openalex.org/S2754427771","display_name":"Journal of UOEH","issn_l":"0387-821X","issn":["0387-821X","2187-2864"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","medline","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313152","host_organization_name":"University of Occupational and Environmental Health Japan","host_organization_lineage":["https://openalex.org/P4310313152"],"host_organization_lineage_names":["University of Occupational and Environmental Health Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of UOEH","raw_type":"journal-article"},{"id":"pmid:21226422","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21226422","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of UOEH","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.7888/juoeh.32.317","doi":"https://doi.org/10.7888/juoeh.32.317","is_oa":true,"landing_page_url":"https://doi.org/10.7888/juoeh.32.317","pdf_url":"https://www.jstage.jst.go.jp/article/juoeh/32/4/32_KJ00006772460/_pdf","source":{"id":"https://openalex.org/S2754427771","display_name":"Journal of UOEH","issn_l":"0387-821X","issn":["0387-821X","2187-2864"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","medline","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313152","host_organization_name":"University of Occupational and Environmental Health Japan","host_organization_lineage":["https://openalex.org/P4310313152"],"host_organization_lineage_names":["University of Occupational and Environmental Health Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of UOEH","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W27810290.pdf","grobid_xml":"https://content.openalex.org/works/W27810290.grobid-xml"},"referenced_works_count":2,"referenced_works":["https://openalex.org/W2042194530","https://openalex.org/W2164098277"],"related_works":["https://openalex.org/W2073037264","https://openalex.org/W2325612512","https://openalex.org/W2343310065","https://openalex.org/W2074753880","https://openalex.org/W2775663182","https://openalex.org/W2268568163","https://openalex.org/W1979058179","https://openalex.org/W2153511580","https://openalex.org/W2012077729","https://openalex.org/W2127294570"],"abstract_inverted_index":{"T":[0,107,120],"helper":[1],"(Th)":[2],"17":[3],"cells":[4,24,88,108,207,260,273,300,311,320],"have":[5,84,246],"crucial":[6,147],"functions":[7],"in":[8,91,98,115,134,224,251,265,276,303,314,325,349],"host":[9],"defense,":[10],"and":[11,20,28,37,49,69,74,123,126,170,181,192,200,286,321,334],"dysregulated":[12],"Th17":[13,23,87,143,187,259,272,299,310,319],"responses":[14],"mediate":[15],"a":[16,57],"variety":[17],"of":[18,59,65,94,103,106,118,151,158,165,172,218,227,236,254,258,271,280,291,308,353],"autoimmune":[19],"inflammatory":[21],"conditions.":[22],"coexpress":[25],"interleukin":[26],"(IL)-22,":[27],"its":[29,75,243],"receptor":[30,245],"is":[31,130,140,190,193,274,295],"expressed":[32],"on":[33],"epidermal":[34],"keratinocytes.":[35,152],"IL-17":[36,48,61,159,333],"IL-22":[38,78,129,139,154,322,335],"cooperatively":[39,336],"enhance":[40],"some":[41],"immunological":[42],"responses.":[43,268],"A":[44],"close":[45],"relationship":[46],"between":[47],"the":[50,63,92,104,116,131,135,149,156,162,225,233,252,277,289,304,346,350],"cutaneous":[51],"milieu":[52],"has":[53,79,112,229,261],"been":[54,80,113,230,248,263],"suggested":[55,85],"by":[56,72,142,216,232],"number":[58],"observations.":[60],"induces":[62],"production":[64],"certain":[66,95],"cytokines,":[67],"chemokines":[68],"antimicrobial":[70,182],"peptides":[71],"keratinocytes,":[73],"cooperation":[76],"with":[77,155,282,288,327],"documented.":[81],"Recent":[82],"findings":[83],"that":[86],"profoundly":[89],"participate":[90],"pathogenesis":[93,226],"skin":[96],"disorders,":[97],"particular,":[99],"psoriasis.":[100,255],"The":[101,220,256,269,306],"concept":[102],"subsets":[105],"responsible":[109],"for":[110,148],"psoriasis":[111,228],"modified":[114],"order":[117],"Th1,":[119],"cytotoxic":[121],"1,":[122],"again":[124],"Thl,":[125],"Thl7":[127],"cells.":[128],"strongest":[132],"cytokine":[133,222],"keratinocyte-proliferative":[136],"ability.":[137],"Since":[138,332],"produced":[141],"cells,":[144,188],"they":[145],"are":[146,210,301,312,323],"proliferation":[150],"Furthermore,":[153],"help":[157],"can":[160],"induce":[161],"critical":[163],"events":[164],"psoriasis,":[166],"including":[167],"signal":[168],"transducer":[169],"activator":[171],"transcription":[173],"3":[174],"(STAT3)":[175],"activation,":[176],"cytokine/chemokine":[177],"(IL-8":[178],"etc.)":[179],"production,":[180],"peptide":[183],"elaboration.":[184],"For":[185],"maintaining":[186],"IL-23":[189],"required":[191],"released":[194],"from":[195],"tumor":[196],"necrosis":[197],"factor-alpha":[198],"(TNF-alpha)":[199],"inducible":[201],"nitric":[202],"oxide":[203],"synthetase":[204],"(iNOS)-producing":[205],"dendritic":[206],"(TIP-DCs).":[208],"TIP-DCs":[209],"activated":[211],"via":[212],"an":[213],"autocrine":[214],"mechanism":[215],"virtue":[217],"TNF-alpha.":[219],"above":[221],"network":[223],"proven":[231],"therapeutic":[234],"effectiveness":[235],"cytokine-blocking":[237],"biologics.":[238],"Antibodies":[239],"against":[240],"TNF-alpha":[241],"or":[242],"soluble":[244],"already":[247],"widely":[249],"used":[250],"treatment":[253],"involvement":[257],"also":[262],"shown":[264],"allergen-specific":[266],"immune":[267],"percentage":[270,307],"increased":[275,313,324],"peripheral":[278],"blood":[279],"patients":[281,326],"atopic":[283],"dermatitis":[284],"(AD)":[285],"associated":[287],"severity":[290],"AD.":[292],"Drug":[293],"eruption":[294],"another":[296],"disease":[297],"where":[298],"involved":[302],"pathogenesis.":[305],"circulating":[309],"drug-induced":[315],"hypersensitivity":[316],"syndrome,":[317],"etc.":[318],"acute":[328],"generalized":[329],"exanthematous":[330],"pustulosis.":[331],"stimulate":[337],"keratinocytes":[338],"to":[339,345],"produce":[340],"IL-8,":[341],"keratinocyte-derived":[342],"IL-8":[343],"contributes":[344],"accumulation":[347],"ofneutrophils":[348],"lesional":[351],"epidermis":[352],"this":[354],"drug":[355],"eruption.":[356]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":11},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":11}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}