{"id":"https://openalex.org/W2778024192","doi":"https://doi.org/10.1002/stem.2767","title":"Bmi1+ Progenitor Cell Dynamics in Murine Cornea During Homeostasis and Wound Healing","display_name":"Bmi1+ Progenitor Cell Dynamics in Murine Cornea During Homeostasis and Wound Healing","publication_year":2017,"publication_date":"2017-12-28","ids":{"openalex":"https://openalex.org/W2778024192","doi":"https://doi.org/10.1002/stem.2767","mag":"2778024192","pmid":"https://pubmed.ncbi.nlm.nih.gov/29282831","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5929111"},"language":"en","primary_location":{"id":"doi:10.1002/stem.2767","doi":"https://doi.org/10.1002/stem.2767","is_oa":true,"landing_page_url":"https://doi.org/10.1002/stem.2767","pdf_url":"https://stemcellsjournals.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/stem.2767","source":{"id":"https://openalex.org/S65139510","display_name":"Stem Cells","issn_l":"1066-5099","issn":["1066-5099","1549-4918"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cells","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://stemcellsjournals.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/stem.2767","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010601447","display_name":"Solja Kalha","orcid":"https://orcid.org/0000-0002-0669-351X","observed_orcids":["https://orcid.org/0000-0002-0669-351X"]},"institutions":[{"id":"https://openalex.org/I133731052","display_name":"University of Helsinki","ror":"https://ror.org/040af2s02","country_code":"FI","type":"education","lineage":["https://openalex.org/I133731052"]},{"id":"https://openalex.org/I4391768107","display_name":"HiLIFE \u2013 El\u00e4m\u00e4ntieteiden Instituutti","ror":"https://ror.org/018bh0m68","country_code":"FI","type":"facility","lineage":["https://openalex.org/I133731052","https://openalex.org/I4391768107"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Solja Kalha","raw_affiliation_strings":["Helsinki Institute of Life Science, Institute of Biotechnology, University of Helsinki, Helsinki, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Helsinki Institute of Life Science, Institute of Biotechnology, University of Helsinki, Helsinki, Finland","institution_ids":["https://openalex.org/I133731052","https://openalex.org/I4391768107"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077865061","display_name":"Bideep Shrestha","orcid":"https://orcid.org/0000-0002-0122-0705","observed_orcids":["https://orcid.org/0000-0002-0122-0705"]},"institutions":[{"id":"https://openalex.org/I133731052","display_name":"University of Helsinki","ror":"https://ror.org/040af2s02","country_code":"FI","type":"education","lineage":["https://openalex.org/I133731052"]},{"id":"https://openalex.org/I4391768107","display_name":"HiLIFE \u2013 El\u00e4m\u00e4ntieteiden Instituutti","ror":"https://ror.org/018bh0m68","country_code":"FI","type":"facility","lineage":["https://openalex.org/I133731052","https://openalex.org/I4391768107"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Bideep Shrestha","raw_affiliation_strings":["Helsinki Institute of Life Science, Institute of Biotechnology, University of Helsinki, Helsinki, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Helsinki Institute of Life Science, Institute of Biotechnology, University of Helsinki, Helsinki, Finland","institution_ids":["https://openalex.org/I133731052","https://openalex.org/I4391768107"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031888410","display_name":"Maria Sanz Navarro","orcid":"https://orcid.org/0000-0002-9476-7928","observed_orcids":["https://orcid.org/0000-0002-9476-7928"]},"institutions":[{"id":"https://openalex.org/I133731052","display_name":"University of Helsinki","ror":"https://ror.org/040af2s02","country_code":"FI","type":"education","lineage":["https://openalex.org/I133731052"]},{"id":"https://openalex.org/I4391768107","display_name":"HiLIFE \u2013 El\u00e4m\u00e4ntieteiden Instituutti","ror":"https://ror.org/018bh0m68","country_code":"FI","type":"facility","lineage":["https://openalex.org/I133731052","https://openalex.org/I4391768107"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Maria Sanz Navarro","raw_affiliation_strings":["Helsinki Institute of Life Science, Institute of Biotechnology, University of Helsinki, Helsinki, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Helsinki Institute of Life Science, Institute of Biotechnology, University of Helsinki, Helsinki, Finland","institution_ids":["https://openalex.org/I133731052","https://openalex.org/I4391768107"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086452771","display_name":"Kyle B. Jones","orcid":"https://orcid.org/0000-0002-5227-3823","observed_orcids":["https://orcid.org/0000-0002-5227-3823"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kyle B. Jones","raw_affiliation_strings":["Department of Orofacial Sciences and Program in Craniofacial Biology, University of California San Francisco, San Francisco, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orofacial Sciences and Program in Craniofacial Biology, University of California San Francisco, San Francisco, California, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017487346","display_name":"Ophir D. Klein","orcid":"https://orcid.org/0000-0002-6254-7082","observed_orcids":["https://orcid.org/0000-0002-6254-7082"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ophir D. Klein","raw_affiliation_strings":["Department of Orofacial Sciences and Program in Craniofacial Biology, University of California San Francisco, San Francisco, California, USA","Department of Pediatrics and Institute for Human Genetics, University of California San Francisco, San Francisco, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orofacial Sciences and Program in Craniofacial Biology, University of California San Francisco, San Francisco, California, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Pediatrics and Institute for Human Genetics, University of California San Francisco, San Francisco, California, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037345613","display_name":"Fr\u00e9d\u00e9ric Michon","orcid":"https://orcid.org/0000-0003-4305-305X","observed_orcids":["https://orcid.org/0000-0003-4305-305X","https://orcid.org/0000-0003-1289-2133"]},"institutions":[{"id":"https://openalex.org/I133731052","display_name":"University of Helsinki","ror":"https://ror.org/040af2s02","country_code":"FI","type":"education","lineage":["https://openalex.org/I133731052"]},{"id":"https://openalex.org/I4391768107","display_name":"HiLIFE \u2013 El\u00e4m\u00e4ntieteiden Instituutti","ror":"https://ror.org/018bh0m68","country_code":"FI","type":"facility","lineage":["https://openalex.org/I133731052","https://openalex.org/I4391768107"]},{"id":"https://openalex.org/I56007636","display_name":"Keele University","ror":"https://ror.org/00340yn33","country_code":"GB","type":"education","lineage":["https://openalex.org/I56007636"]}],"countries":["FI","GB"],"is_corresponding":true,"raw_author_name":"Frederic Michon","raw_affiliation_strings":["Helsinki Institute of Life Science, Institute of Biotechnology, University of Helsinki, Helsinki, Finland","Keele Medical School and Institute for Science and Technology in Medicine, Keele University, Keele, Staffordshire, England, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0003-4305-305X","affiliations":[{"raw_affiliation_string":"Helsinki Institute of Life Science, Institute of Biotechnology, University of Helsinki, Helsinki, Finland","institution_ids":["https://openalex.org/I133731052","https://openalex.org/I4391768107"]},{"raw_affiliation_string":"Keele Medical School and Institute for Science and Technology in Medicine, Keele University, Keele, Staffordshire, England, United Kingdom","institution_ids":["https://openalex.org/I56007636"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5037345613"],"corresponding_institution_ids":["https://openalex.org/I133731052","https://openalex.org/I4391768107","https://openalex.org/I56007636"],"apc_list":{"value":4477,"currency":"USD","value_usd":4477},"apc_paid":null,"fwci":1.47,"has_fulltext":true,"cited_by_count":18,"citation_normalized_percentile":{"value":0.81082085,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"36","issue":"4","first_page":"562","last_page":"573"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11828","display_name":"Corneal Surgery and Treatments","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11828","display_name":"Corneal Surgery and Treatments","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10997","display_name":"Ocular Surface and Contact Lens","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12989","display_name":"Ocular Disorders and Treatments","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bmi1","display_name":"BMI1","score":0.8619999885559082},{"id":"https://openalex.org/keywords/corneal-wound-healing","display_name":"corneal wound healing","score":0.8669999837875366},{"id":"https://openalex.org/keywords/corneal-homeostasis","display_name":"corneal homeostasis","score":0.9440000057220459},{"id":"https://openalex.org/keywords/corneal-epithelium","display_name":"corneal epithelium","score":0.7300000190734863},{"id":"https://openalex.org/keywords/limbus","display_name":"limbus","score":0.8519999980926514},{"id":"https://openalex.org/keywords/keratin-19","display_name":"keratin 19","score":0.8830000162124634}],"concepts":[{"id":"https://openalex.org/C2776882836","wikidata":"https://www.wikidata.org/wiki/Q168291","display_name":"Cornea","level":2,"score":0.8189824819564819},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7818175554275513},{"id":"https://openalex.org/C2779257441","wikidata":"https://www.wikidata.org/wiki/Q2040445","display_name":"Corneal epithelium","level":3,"score":0.7460893392562866},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.7429325580596924},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.637426495552063},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6358111500740051},{"id":"https://openalex.org/C529295009","wikidata":"https://www.wikidata.org/wiki/Q41301","display_name":"Epithelium","level":2,"score":0.5817925333976746},{"id":"https://openalex.org/C2780269544","wikidata":"https://www.wikidata.org/wiki/Q1509074","display_name":"Wound healing","level":2,"score":0.5771763324737549},{"id":"https://openalex.org/C63645605","wikidata":"https://www.wikidata.org/wiki/Q103191","display_name":"Homeostasis","level":2,"score":0.5640684366226196},{"id":"https://openalex.org/C2778987575","wikidata":"https://www.wikidata.org/wiki/Q21145992","display_name":"BMI1","level":3,"score":0.4775479733943939},{"id":"https://openalex.org/C2778024521","wikidata":"https://www.wikidata.org/wiki/Q55639806","display_name":"Basal (medicine)","level":3,"score":0.42422959208488464},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.32130882143974304},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.1529799997806549},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.11799293756484985},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.048142582178115845},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003315","descriptor_name":"Cornea","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003315","descriptor_name":"Cornea","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008813","descriptor_name":"Mice, Inbred ICR","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008817","descriptor_name":"Mice, Mutant Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011518","descriptor_name":"Proto-Oncogene Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D011518","descriptor_name":"Proto-Oncogene Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D014945","descriptor_name":"Wound Healing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063150","descriptor_name":"Polycomb Repressive Complex 1","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D063150","descriptor_name":"Polycomb Repressive Complex 1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D065306","descriptor_name":"Corneal Injuries","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D065306","descriptor_name":"Corneal Injuries","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D065306","descriptor_name":"Corneal Injuries","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1002/stem.2767","doi":"https://doi.org/10.1002/stem.2767","is_oa":true,"landing_page_url":"https://doi.org/10.1002/stem.2767","pdf_url":"https://stemcellsjournals.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/stem.2767","source":{"id":"https://openalex.org/S65139510","display_name":"Stem Cells","issn_l":"1066-5099","issn":["1066-5099","1549-4918"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cells","raw_type":"journal-article"},{"id":"pmid:29282831","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29282831","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem cells (Dayton, Ohio)","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:5422422","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5929111","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5929111","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5929111","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Stem Cells","raw_type":"Text"},{"id":"pmh:oai:eprints.keele.ac.uk:4569","doi":null,"is_oa":true,"landing_page_url":"http://eprints.keele.ac.uk/4569/1/F%20Michon%20-%20Bmi1%2B%20progenitor%20cell%20dynamics%20in%20murine%20cornea%20during....pdf","pdf_url":"http://eprints.keele.ac.uk/4569/1/F%20Michon%20-%20Bmi1%2B%20progenitor%20cell%20dynamics%20in%20murine%20cornea%20during....pdf","source":{"id":"https://openalex.org/S4306402149","display_name":"Keele Research Repository (Keele University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I56007636","host_organization_name":"Keele University","host_organization_lineage":["https://openalex.org/I56007636"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:HAL:hal-04865509v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-04865509","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"STEM CELLS, 2018, 36 (4), pp.562-573. ⟨10.1002/stem.2767⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt4g1613kr","doi":null,"is_oa":false,"landing_page_url":"https://escholarship.org/uc/item/4g1613kr","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Stem Cells, vol 36, iss 4","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1002/stem.2767","doi":"https://doi.org/10.1002/stem.2767","is_oa":true,"landing_page_url":"https://doi.org/10.1002/stem.2767","pdf_url":"https://stemcellsjournals.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/stem.2767","source":{"id":"https://openalex.org/S65139510","display_name":"Stem Cells","issn_l":"1066-5099","issn":["1066-5099","1549-4918"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cells","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6240000128746033}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G8665273439","display_name":"Harnessing natural stem cell-based strategies for mammalian dental renewal","funder_award_id":"R35DE026602","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"}],"funders":[{"id":"https://openalex.org/F4320310086","display_name":"Helsingin Yliopisto","ror":"https://ror.org/040af2s02"},{"id":"https://openalex.org/F4320321108","display_name":"Academy of Finland","ror":"https://ror.org/05k73zm37"},{"id":"https://openalex.org/F4320322282","display_name":"Jane ja Aatos Erkon S\u00e4\u00e4ti\u00f6","ror":"https://ror.org/03vxy9y38"},{"id":"https://openalex.org/F4320337365","display_name":"National Institute of Dental and Craniofacial Research","ror":"https://ror.org/004a2wv92"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2778024192.pdf","grobid_xml":"https://content.openalex.org/works/W2778024192.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W120415665","https://openalex.org/W163285829","https://openalex.org/W1481473039","https://openalex.org/W1515583925","https://openalex.org/W1572223735","https://openalex.org/W1768274470","https://openalex.org/W1975326463","https://openalex.org/W1979931593","https://openalex.org/W1987298940","https://openalex.org/W1987690014","https://openalex.org/W1990054592","https://openalex.org/W1996310802","https://openalex.org/W1999295970","https://openalex.org/W2003299661","https://openalex.org/W2011585659","https://openalex.org/W2018585727","https://openalex.org/W2021050536","https://openalex.org/W2021612760","https://openalex.org/W2021992179","https://openalex.org/W2029073164","https://openalex.org/W2040743587","https://openalex.org/W2043272632","https://openalex.org/W2050314360","https://openalex.org/W2067920606","https://openalex.org/W2068190122","https://openalex.org/W2071187736","https://openalex.org/W2075688585","https://openalex.org/W2087438030","https://openalex.org/W2090856763","https://openalex.org/W2091614705","https://openalex.org/W2092411127","https://openalex.org/W2105974295","https://openalex.org/W2106941210","https://openalex.org/W2119226652","https://openalex.org/W2123791127","https://openalex.org/W2126701927","https://openalex.org/W2128078747","https://openalex.org/W2153463588","https://openalex.org/W2153571086","https://openalex.org/W2158671243","https://openalex.org/W2163674890","https://openalex.org/W2194436742","https://openalex.org/W2251648818","https://openalex.org/W2341773516","https://openalex.org/W2758373566","https://openalex.org/W2895653851","https://openalex.org/W6604953201","https://openalex.org/W6634420449"],"related_works":["https://openalex.org/W3153267130","https://openalex.org/W2996775712","https://openalex.org/W2158671243","https://openalex.org/W1515583925","https://openalex.org/W2530832389","https://openalex.org/W1821650137","https://openalex.org/W4415641245","https://openalex.org/W3201045357","https://openalex.org/W2992947825","https://openalex.org/W4240702655"],"abstract_inverted_index":{"The":[0],"outermost":[1],"layer":[2,46],"of":[3,15,30,47,74,86,108,135],"the":[4,6,16,21,24,31,44,48,59,105,109,125,136],"eye,":[5],"cornea,":[7],"is":[8,102],"renewed":[9],"continuously":[10],"throughout":[11],"life.":[12],"Stem":[13,167],"cells":[14,41,91,119,130,156],"corneal":[17,25,50,56,75,88],"epithelium":[18,107],"reside":[19],"in":[20,35,43,104,121,124],"limbus":[22],"at":[23],"periphery":[26],"and":[27,65,94,97,112],"ensure":[28],"homeostasis":[29,38,134],"central":[32,49,110,126],"epithelium.":[33,51],"However,":[34],"young":[36],"mice,":[37],"relies":[39],"on":[40],"located":[42],"basal":[45,106],"Here,":[52],"we":[53,78,98,115],"first":[54],"studied":[55],"growth":[57],"during":[58,93],"transition":[60],"from":[61],"newborn":[62],"to":[63,81],"adult":[64],"assessed":[66],"Keratin":[67],"19":[68],"(Krt19)":[69],"expression":[70],"as":[71,146],"a":[72,83],"hallmark":[73],"maturation.":[76],"Next,":[77],"set":[79],"out":[80],"identify":[82],"novel":[84],"marker":[85],"murine":[87],"epithelial":[89,165],"progenitor":[90,147],"before,":[92],"after":[95,153],"maturation,":[96],"found":[99],"that":[100,117],"Bmi1":[101],"expressed":[103],"cornea":[111,137],"limbus.":[113],"Furthermore,":[114],"demonstrated":[116],"Bmi1+":[118,129,155],"participated":[120],"tissue":[122],"replenishment":[123],"cornea.":[127],"These":[128],"did":[131],"not":[132],"maintain":[133],"for":[138],"more":[139],"than":[140,149],"3":[141],"months,":[142],"reflecting":[143],"their":[144],"status":[145],"rather":[148],"stem":[150],"cells.":[151],"Finally,":[152],"injury,":[154],"fueled":[157],"homeostatic":[158],"maintenance,":[159],"whereas":[160],"wound":[161],"closure":[162],"occurred":[163],"via":[164],"reorganization.":[166],"Cells":[168],"2018;36:562-573.":[169]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-01-05T00:00:00"}