{"id":"https://openalex.org/W2777098513","doi":"https://doi.org/10.21037/cdt.2017.10.09","title":"Drug-eluting balloons with provisional bail-out or adjunctive stenting in de novo coronary artery lesions\u2014a systematic review and meta-analysis","display_name":"Drug-eluting balloons with provisional bail-out or adjunctive stenting in de novo coronary artery lesions\u2014a systematic review and meta-analysis","publication_year":2018,"publication_date":"2018-04-01","ids":{"openalex":"https://openalex.org/W2777098513","doi":"https://doi.org/10.21037/cdt.2017.10.09","mag":"2777098513","pmid":"https://pubmed.ncbi.nlm.nih.gov/29850403"},"language":"en","primary_location":{"id":"doi:10.21037/cdt.2017.10.09","doi":"https://doi.org/10.21037/cdt.2017.10.09","is_oa":true,"landing_page_url":"https://doi.org/10.21037/cdt.2017.10.09","pdf_url":"https://cdt.amegroups.com/article/viewFile/17779/pdf","source":{"id":"https://openalex.org/S2764634846","display_name":"Cardiovascular Diagnosis and Therapy","issn_l":"2223-3652","issn":["2223-3652","2223-3660"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","ki-jl-1","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310321814","host_organization_name":"AME Publishing Company","host_organization_lineage":["https://openalex.org/P4310321814"],"host_organization_lineage_names":["AME Publishing Company"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiovascular Diagnosis and Therapy","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://cdt.amegroups.com/article/viewFile/17779/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102999732","display_name":"Smit Patel","orcid":"https://orcid.org/0000-0002-9186-0430","observed_orcids":["https://orcid.org/0000-0002-9186-0430"]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Smit Patel","raw_affiliation_strings":["Vascular Biology, Cardiovascular Science, National Heart & Lung Institute (NHLI), Faculty of Medicine, Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vascular Biology, Cardiovascular Science, National Heart & Lung Institute (NHLI), Faculty of Medicine, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036041916","display_name":"Tatiana Svermova","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tatiana Svermova","raw_affiliation_strings":["Vascular Biology, Cardiovascular Science, National Heart & Lung Institute (NHLI), Faculty of Medicine, Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vascular Biology, Cardiovascular Science, National Heart & Lung Institute (NHLI), Faculty of Medicine, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036445499","display_name":"Anne Burke-Gaffney Burke-Gaffney","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anne Burke-Gaffney Burke-Gaffney","raw_affiliation_strings":["Vascular Biology, Cardiovascular Science, National Heart & Lung Institute (NHLI), Faculty of Medicine, Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vascular Biology, Cardiovascular Science, National Heart & Lung Institute (NHLI), Faculty of Medicine, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056800378","display_name":"Richard Bogle","orcid":"https://orcid.org/0000-0002-8300-3367","observed_orcids":["https://orcid.org/0000-0002-8300-3367","https://orcid.org/0000-0001-7071-8534"]},"institutions":[{"id":"https://openalex.org/I2801196673","display_name":"St George\u2019s University Hospitals NHS Foundation Trust","ror":"https://ror.org/039zedc16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801196673"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Richard G. Bogle","raw_affiliation_strings":["Cardiology Clinical Academic Group, St George's University Foundation Hospitals NHS Trust, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiology Clinical Academic Group, St George's University Foundation Hospitals NHS Trust, London, UK","institution_ids":["https://openalex.org/I2801196673"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5056800378"],"corresponding_institution_ids":["https://openalex.org/I2801196673"],"apc_list":null,"apc_paid":null,"fwci":0.2516,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.31485149,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"8","issue":"2","first_page":"121","last_page":"136"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11064","display_name":"Antiplatelet Therapy and Cardiovascular Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/drug-coated-balloon","display_name":"drug-coated balloon","score":0.9980000257492065},{"id":"https://openalex.org/keywords/bare-metal-stents","display_name":"bare-metal stents","score":0.9610000252723694},{"id":"https://openalex.org/keywords/drug-eluting-stents","display_name":"drug-eluting stents","score":0.8960000276565552},{"id":"https://openalex.org/keywords/de-novo-coronary-lesions","display_name":"de novo coronary lesions","score":0.7990000247955322},{"id":"https://openalex.org/keywords/late-lumen-loss","display_name":"late lumen loss","score":0.8199999928474426},{"id":"https://openalex.org/keywords/binary-restenosis","display_name":"binary restenosis","score":0.9660000205039978},{"id":"https://openalex.org/keywords/major-adverse-cardiac-events","display_name":"major adverse cardiac events","score":0.9869999885559082},{"id":"https://openalex.org/keywords/target-lesion-revascularization","display_name":"target lesion revascularization","score":0.9020000100135803},{"id":"https://openalex.org/keywords/bifurcation-lesions","display_name":"bifurcation lesions","score":0.9139999747276306},{"id":"https://openalex.org/keywords/plain-balloon-angioplasty","display_name":"plain old balloon angioplasty","score":0.8450000286102295},{"id":"https://openalex.org/keywords/stent-thrombosis","display_name":"stent thrombosis","score":0.8050000071525574}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9633176326751709},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.5523826479911804},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.5447885990142822},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4973500072956085},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.48175477981567383},{"id":"https://openalex.org/C2776820930","wikidata":"https://www.wikidata.org/wiki/Q9655","display_name":"Artery","level":2,"score":0.45557278394699097},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.32385021448135376},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.12087491154670715}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.21037/cdt.2017.10.09","doi":"https://doi.org/10.21037/cdt.2017.10.09","is_oa":true,"landing_page_url":"https://doi.org/10.21037/cdt.2017.10.09","pdf_url":"https://cdt.amegroups.com/article/viewFile/17779/pdf","source":{"id":"https://openalex.org/S2764634846","display_name":"Cardiovascular Diagnosis and Therapy","issn_l":"2223-3652","issn":["2223-3652","2223-3660"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","ki-jl-1","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310321814","host_organization_name":"AME Publishing Company","host_organization_lineage":["https://openalex.org/P4310321814"],"host_organization_lineage_names":["AME Publishing Company"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiovascular Diagnosis and Therapy","raw_type":"journal-article"},{"id":"pmid:29850403","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29850403","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiovascular diagnosis and therapy","raw_type":"Journal Article"},{"id":"pmh:oai:openaccess.sgul.ac.uk:112630","doi":null,"is_oa":false,"landing_page_url":"http://openaccess.sgul.ac.uk/112630/1/cdt-08-02-121.pdf","pdf_url":"http://openaccess.sgul.ac.uk/112630/1/cdt-08-02-121.pdf","source":{"id":"https://openalex.org/S4306400552","display_name":"St George's Online Research Archive (St George's University of London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I165862685","host_organization_name":"St George's, University of London","host_organization_lineage":["https://openalex.org/I165862685"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:europepmc.org:4924439","doi":null,"is_oa":false,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5951997","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5951997","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5951997","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cardiovasc Diagn Ther","raw_type":"Text"},{"id":"pmh:oai:spiral.imperial.ac.uk:10044/1/60009","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10044/1/60009","pdf_url":null,"source":{"id":"https://openalex.org/S4306401396","display_name":"Spiral (Imperial College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I47508984","host_organization_name":"Imperial College London","host_organization_lineage":["https://openalex.org/I47508984"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"136","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.21037/cdt.2017.10.09","doi":"https://doi.org/10.21037/cdt.2017.10.09","is_oa":true,"landing_page_url":"https://doi.org/10.21037/cdt.2017.10.09","pdf_url":"https://cdt.amegroups.com/article/viewFile/17779/pdf","source":{"id":"https://openalex.org/S2764634846","display_name":"Cardiovascular Diagnosis and Therapy","issn_l":"2223-3652","issn":["2223-3652","2223-3660"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","ki-jl-1","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310321814","host_organization_name":"AME Publishing Company","host_organization_lineage":["https://openalex.org/P4310321814"],"host_organization_lineage_names":["AME Publishing Company"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiovascular Diagnosis and Therapy","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8600000143051147}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[{"id":"https://openalex.org/G4004371361","display_name":"SRAGE-activated endothelial barrier dysfunction: a possible link to glycocalyx and Robo4 disruption","funder_award_id":"FS/14/6/30573","funder_id":"https://openalex.org/F4320319992","funder_display_name":"British Heart Foundation"}],"funders":[{"id":"https://openalex.org/F4320319992","display_name":"British Heart Foundation","ror":"https://ror.org/02wdwnk04"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2777098513.pdf","grobid_xml":"https://content.openalex.org/works/W2777098513.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W1523112201","https://openalex.org/W1540449155","https://openalex.org/W1572321976","https://openalex.org/W1895932837","https://openalex.org/W1927281941","https://openalex.org/W1976235521","https://openalex.org/W1983921821","https://openalex.org/W1984992241","https://openalex.org/W2008622647","https://openalex.org/W2011203330","https://openalex.org/W2035338439","https://openalex.org/W2037146940","https://openalex.org/W2040868595","https://openalex.org/W2053320723","https://openalex.org/W2068369907","https://openalex.org/W2068951517","https://openalex.org/W2070408651","https://openalex.org/W2088525997","https://openalex.org/W2088541427","https://openalex.org/W2092726265","https://openalex.org/W2099945423","https://openalex.org/W2102528608","https://openalex.org/W2103766009","https://openalex.org/W2115082050","https://openalex.org/W2115824015","https://openalex.org/W2117973761","https://openalex.org/W2121893194","https://openalex.org/W2132270253","https://openalex.org/W2139804268","https://openalex.org/W2140676515","https://openalex.org/W2147093613","https://openalex.org/W2150086052","https://openalex.org/W2165349656","https://openalex.org/W2169383303","https://openalex.org/W2184506935","https://openalex.org/W2238883126","https://openalex.org/W2327479291","https://openalex.org/W2338107051","https://openalex.org/W2413714534","https://openalex.org/W2472545068","https://openalex.org/W2549125387","https://openalex.org/W2597619114","https://openalex.org/W2610707782","https://openalex.org/W4236067666","https://openalex.org/W4236531408","https://openalex.org/W4406455795","https://openalex.org/W6921604777"],"related_works":["https://openalex.org/W4387497383","https://openalex.org/W3183948672","https://openalex.org/W3173606202","https://openalex.org/W3110381201","https://openalex.org/W2948807893","https://openalex.org/W2935909890","https://openalex.org/W2778153218","https://openalex.org/W2758277628","https://openalex.org/W1531601525","https://openalex.org/W3210678099"],"abstract_inverted_index":{"BACKGROUND:":[0],"coronary":[1],"lesions":[2,188],"remains":[3],"controversial.":[4],"The":[5],"present":[6],"systematic":[7,45],"review":[8],"and":[9,21,39,63,82,123,151,175,214],"meta-analysis":[10],"of":[11],"randomised":[12],"controlled":[13],"trials":[14],"assessed":[15],"DEB":[16,23,101,135,160,198],"with":[17,24,92,102,136],"bare-metal":[18],"stents":[19,27,41],"(BMS)":[20],"also":[22],"provisional":[25],"bail-out":[26],"('DEB-only'":[28],"strategy),":[29],"to":[30,106,120,132,140,148,156,164,172,181,196,207],"other":[31],"conventional":[32],"options:":[33],"plain-old":[34],"balloon":[35],"angioplasty":[36],"(POBA),":[37],"BMS":[38,103,137,141],"drug-eluting":[40],"(DES).":[42],"METHODS:":[43],"A":[44],"literature":[46],"search":[47],"from":[48],"January":[49],"2000":[50],"until":[51],"May":[52],"2017":[53],"was":[54,138,162],"conducted.":[55],"Primary":[56],"outcome":[57],"measure,":[58],"late":[59],"lumen":[60],"loss":[61],"(LLL);":[62],"secondary":[64],"outcomes;":[65],"binary":[66,124,176],"restenosis,":[67],"major":[68],"adverse":[69],"cardiac":[70],"events":[71],"(MACE),":[72],"target":[73],"lesion":[74],"revascularization":[75],"(TLR),":[76],"myocardial":[77],"infarction":[78],"(MI),":[79],"cardiovascular":[80],"death":[81],"stent":[83],"thrombosis":[84],"were":[85,90,104],"analysed.":[86],"RESULTS:":[87],"Seventeen":[88],"RCTs":[89],"included":[91],"2,616":[93],"patients.":[94],"Several":[95],"comparative":[96],"groups":[97],"showed":[98],"significant":[99],"differences.":[100],"inferior":[105],"DES":[107,208],"for":[108,142,166,204],"LLL":[109,143,167],"[mean":[110],"difference":[111],"(MD)":[112],"=0.12":[113],"mm;":[114,146,170],"95%":[115],"confidence":[116],"interval":[117],"(CI),":[118],"0.03":[119],"0.22;":[121],"P=0.01];":[122],"restenosis":[125,177],"[risk":[126],"ratio":[127],"(RR)":[128],"=1.89;":[129],"(CI,":[130],"1.13":[131],"3.18);":[133],"P=0.02].":[134],"superior":[139,163],"[MD":[144,168],"=-0.27":[145],"(-0.45":[147],"-0.10);":[149],"P=0.002];":[150],"MACE":[152],"[RR":[153,178],"=0.64;":[154],"(0.46":[155],"0.90);":[157],"P=0.010].":[158],"Finally,":[159],"alone":[161],"POBA":[165],"=-0.39":[169],"(-0.67":[171],"-0.11);":[173],"P=0.006]":[174],"=0.20;":[179],"(0.05":[180],"0.85);":[182],"P=0.03]":[183],"in":[184,190],"bifurcation":[185,215],"lesions.":[186,216],"CONCLUSIONS:":[187],"unless":[189],"patients":[191],"who":[192],"have":[193],"absolute":[194],"contraindications":[195,206],"DES.":[197],"alone,":[199],"however,":[200],"should":[201],"be":[202],"considered":[203],"relative":[205],"such":[209],"as":[210],"small":[211],"vessel":[212],"disease":[213]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}
