{"id":"https://openalex.org/W2776347992","doi":"https://doi.org/10.1007/s12195-017-0517-4","title":"Generating Chondromimetic Mesenchymal Stem Cell Spheroids by Regulating Media Composition and Surface Coating","display_name":"Generating Chondromimetic Mesenchymal Stem Cell Spheroids by Regulating Media Composition and Surface Coating","publication_year":2017,"publication_date":"2017-12-22","ids":{"openalex":"https://openalex.org/W2776347992","doi":"https://doi.org/10.1007/s12195-017-0517-4","mag":"2776347992","pmid":"https://pubmed.ncbi.nlm.nih.gov/29623134","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5880050"},"language":"en","primary_location":{"id":"doi:10.1007/s12195-017-0517-4","doi":"https://doi.org/10.1007/s12195-017-0517-4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s12195-017-0517-4","pdf_url":null,"source":{"id":"https://openalex.org/S77874066","display_name":"Cellular and Molecular Bioengineering","issn_l":"1865-5025","issn":["1865-5025","1865-5033"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular and Molecular Bioengineering","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5880050","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062551876","display_name":"BanuPriya Sridharan","orcid":"https://orcid.org/0000-0003-3949-5226","observed_orcids":["https://orcid.org/0000-0003-3949-5226"]},"institutions":[{"id":"https://openalex.org/I146416000","display_name":"University of Kansas","ror":"https://ror.org/001tmjg57","country_code":"US","type":"education","lineage":["https://openalex.org/I146416000"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"BanuPriya Sridharan","raw_affiliation_strings":["Bioengineering Program, University of Kansas, Lawrence, KS, 66045, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering Program, University of Kansas, Lawrence, KS, 66045, USA","institution_ids":["https://openalex.org/I146416000"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062045456","display_name":"Amy D. Laflin","orcid":"https://orcid.org/0000-0003-2571-2824","observed_orcids":["https://orcid.org/0000-0003-2571-2824"]},"institutions":[{"id":"https://openalex.org/I146416000","display_name":"University of Kansas","ror":"https://ror.org/001tmjg57","country_code":"US","type":"education","lineage":["https://openalex.org/I146416000"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amy D. Laflin","raw_affiliation_strings":["Department of Chemical and Petroleum Engineering, University of Kansas, Lawrence, KS, 66045, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical and Petroleum Engineering, University of Kansas, Lawrence, KS, 66045, USA","institution_ids":["https://openalex.org/I146416000"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103232021","display_name":"Michael S. Detamore","orcid":"https://orcid.org/0000-0002-2584-5507","observed_orcids":["https://orcid.org/0000-0002-2584-5507"]},"institutions":[{"id":"https://openalex.org/I8692664","display_name":"University of Oklahoma","ror":"https://ror.org/02aqsxs83","country_code":"US","type":"education","lineage":["https://openalex.org/I8692664"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael S. Detamore","raw_affiliation_strings":["Stephenson School of Biomedical Engineering, University of Oklahoma, 202\u00a0W. Boyd Street, Carson Engineering Center, Room 107, Norman, OK, 73019-1021, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stephenson School of Biomedical Engineering, University of Oklahoma, 202\u00a0W. Boyd Street, Carson Engineering Center, Room 107, Norman, OK, 73019-1021, USA","institution_ids":["https://openalex.org/I8692664"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5103232021"],"corresponding_institution_ids":["https://openalex.org/I8692664"],"apc_list":{"value":3690,"currency":"USD","value_usd":3690},"apc_paid":null,"fwci":0.4201,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.52281435,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"11","issue":"2","first_page":"99","last_page":"115"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.5151000022888184,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.5151000022888184,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.39329999685287476,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.029100000858306885,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mesenchymal-stem-cells","display_name":"mesenchymal stem cells","score":0.9779999852180481},{"id":"https://openalex.org/keywords/cell-spheroids","display_name":"cell spheroids","score":0.8939999938011169},{"id":"https://openalex.org/keywords/chondrogenic-differentiation","display_name":"chondrogenic differentiation","score":0.9629999995231628},{"id":"https://openalex.org/keywords/cartilage-tissue-engineering","display_name":"cartilage tissue engineering","score":0.8560000061988831},{"id":"https://openalex.org/keywords/culture-medium-composition","display_name":"culture medium composition","score":0.6729999780654907},{"id":"https://openalex.org/keywords/insulin-like-growth-factor","display_name":"insulin-like growth factor","score":0.9169999957084656},{"id":"https://openalex.org/keywords/aggrecan","display_name":"aggrecan","score":0.8199999928474426},{"id":"https://openalex.org/keywords/chondroitin-sulfate","display_name":"chondroitin sulfate","score":1.0},{"id":"https://openalex.org/keywords/glycosaminoglycans","display_name":"glycosaminoglycans","score":0.8930000066757202},{"id":"https://openalex.org/keywords/bone-marrow-derived-stem-cells","display_name":"bone marrow-derived stem cells","score":0.8700000047683716}],"concepts":[{"id":"https://openalex.org/C175369904","wikidata":"https://www.wikidata.org/wiki/Q208395","display_name":"Spheroid","level":3,"score":0.9084409475326538},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.7750931978225708},{"id":"https://openalex.org/C35496256","wikidata":"https://www.wikidata.org/wiki/Q5104524","display_name":"Chondrogenesis","level":3,"score":0.751933217048645},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.7087196111679077},{"id":"https://openalex.org/C197534660","wikidata":"https://www.wikidata.org/wiki/Q21121862","display_name":"Aggrecan","level":5,"score":0.5512184500694275},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.5474385619163513},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5349693894386292},{"id":"https://openalex.org/C153074725","wikidata":"https://www.wikidata.org/wiki/Q407553","display_name":"Glycosaminoglycan","level":2,"score":0.5162782073020935},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.4871818423271179},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.42748284339904785},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.4000629484653473},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.29054662585258484},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15258347988128662},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1343221366405487},{"id":"https://openalex.org/C3020332539","wikidata":"https://www.wikidata.org/wiki/Q2014564","display_name":"Articular cartilage","level":4,"score":0.09416002035140991},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0751078724861145},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.07265859842300415},{"id":"https://openalex.org/C2776164576","wikidata":"https://www.wikidata.org/wiki/Q62736","display_name":"Osteoarthritis","level":3,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1007/s12195-017-0517-4","doi":"https://doi.org/10.1007/s12195-017-0517-4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s12195-017-0517-4","pdf_url":null,"source":{"id":"https://openalex.org/S77874066","display_name":"Cellular and Molecular Bioengineering","issn_l":"1865-5025","issn":["1865-5025","1865-5033"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular and Molecular Bioengineering","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5421206","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5880050","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:29623134","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29623134","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular and molecular bioengineering","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5880050","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5880050/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Cell Mol Bioeng","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:5421206","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5880050","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G5544557957","display_name":"Gradient-based strategy for osteochondral regeneration","funder_award_id":"R01AR056347","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"}],"funders":[{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W11305555","https://openalex.org/W43779440","https://openalex.org/W105600474","https://openalex.org/W1489161277","https://openalex.org/W1589179725","https://openalex.org/W1650284538","https://openalex.org/W1781146795","https://openalex.org/W1914334944","https://openalex.org/W1968526564","https://openalex.org/W1970383871","https://openalex.org/W1973762165","https://openalex.org/W1977640086","https://openalex.org/W1977784832","https://openalex.org/W1977857189","https://openalex.org/W1978578744","https://openalex.org/W1987671596","https://openalex.org/W1988122470","https://openalex.org/W2006601087","https://openalex.org/W2016931709","https://openalex.org/W2021972578","https://openalex.org/W2022632942","https://openalex.org/W2025831725","https://openalex.org/W2026344537","https://openalex.org/W2028046200","https://openalex.org/W2030412907","https://openalex.org/W2036200411","https://openalex.org/W2037536118","https://openalex.org/W2051400613","https://openalex.org/W2059567868","https://openalex.org/W2068322675","https://openalex.org/W2069099635","https://openalex.org/W2071375023","https://openalex.org/W2086316164","https://openalex.org/W2088467036","https://openalex.org/W2093932190","https://openalex.org/W2115886971","https://openalex.org/W2123232388","https://openalex.org/W2132257591","https://openalex.org/W2136648378","https://openalex.org/W2142617116","https://openalex.org/W2147220928","https://openalex.org/W2148004927","https://openalex.org/W2159468893","https://openalex.org/W2321125045","https://openalex.org/W2536353419","https://openalex.org/W2608993677"],"related_works":["https://openalex.org/W3216685861","https://openalex.org/W4404474396","https://openalex.org/W7071254889","https://openalex.org/W4281684373","https://openalex.org/W2057465261","https://openalex.org/W7018004668","https://openalex.org/W2606182420","https://openalex.org/W4393930908","https://openalex.org/W2033534438","https://openalex.org/W2073780634"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2018-01-05T00:00:00"}