{"id":"https://openalex.org/W2774466565","doi":null,"title":"Characterization of physical and cognitive function, physical activity, and sedentary behavior in older adults with multiple sclerosis","display_name":"Characterization of physical and cognitive function, physical activity, and sedentary behavior in older adults with multiple sclerosis","publication_year":2017,"publication_date":"2017-04-12","ids":{"openalex":"https://openalex.org/W2774466565","mag":"2774466565"},"language":"en","primary_location":{"id":"pmh:oai:www.ideals.illinois.edu:2142/97331","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2142/97331","pdf_url":"http://hdl.handle.net/2142/97331","source":{"id":"https://openalex.org/S4306401358","display_name":"Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801919071","host_organization_name":"University of Illinois System","host_organization_lineage":["https://openalex.org/I2801919071"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/2142/97331","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026908498","display_name":"Rachel E. Bollaert","orcid":"https://orcid.org/0000-0002-2448-990X","observed_orcids":["https://orcid.org/0000-0002-2448-990X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Rachel E. Bollaert","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6942-7449","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5026908498"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.23596948,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.9077000021934509,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.9077000021934509,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10352","display_name":"Physical Activity and Health","score":0.07909999787807465,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10114","display_name":"Balance, Gait, and Falls Prevention","score":0.004699999932199717,"subfield":{"id":"https://openalex.org/subfields/3612","display_name":"Physical Therapy, Sports Therapy and Rehabilitation"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multiple-sclerosis","display_name":"multiple sclerosis","score":0.9890000224113464},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.9980000257492065},{"id":"https://openalex.org/keywords/physical-functioning","display_name":"physical function","score":0.9819999933242798},{"id":"https://openalex.org/keywords/cognitive-function","display_name":"cognitive function","score":0.9990000128746033},{"id":"https://openalex.org/keywords/processing-speed","display_name":"processing speed","score":0.9490000009536743},{"id":"https://openalex.org/keywords/exercise","display_name":"physical activity","score":0.902999997138977},{"id":"https://openalex.org/keywords/sedentary-behavior","display_name":"sedentary behavior","score":0.9369999766349792},{"id":"https://openalex.org/keywords/moderate-to-vigorous-physical-activity","display_name":"moderate-to-vigorous physical activity","score":0.9940000176429749},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.6589999794960022},{"id":"https://openalex.org/keywords/disease-progression","display_name":"disease progression","score":0.628000020980835},{"id":"https://openalex.org/keywords/cognitive-rehabilitation","display_name":"cognitive rehabilitation","score":0.4390000104904175},{"id":"https://openalex.org/keywords/older-adults-with-chronic-disease","display_name":"chronic diseases in older adults","score":0.41600000858306885},{"id":"https://openalex.org/keywords/healthy-aging","display_name":"healthy aging","score":0.34200000762939453},{"id":"https://openalex.org/keywords/fall-risk","display_name":"fall risk","score":0.32199999690055847},{"id":"https://openalex.org/keywords/walking-speed","display_name":"walking speed","score":0.656000018119812},{"id":"https://openalex.org/keywords/muscle-strength","display_name":"muscle strength","score":0.47200000286102295}],"concepts":[{"id":"https://openalex.org/C2780640218","wikidata":"https://www.wikidata.org/wiki/Q8277","display_name":"Multiple sclerosis","level":2,"score":0.6973627805709839},{"id":"https://openalex.org/C2987988905","wikidata":"https://www.wikidata.org/wiki/Q1349358","display_name":"Sedentary behavior","level":3,"score":0.5899191498756409},{"id":"https://openalex.org/C3020255362","wikidata":"https://www.wikidata.org/wiki/Q747883","display_name":"Physical activity","level":2,"score":0.5744355916976929},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.5547425746917725},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.5176377892494202},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.5046068429946899},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.43944334983825684},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3985854387283325},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.36525899171829224},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.20964661240577698},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.09920108318328857}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:www.ideals.illinois.edu:2142/97331","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2142/97331","pdf_url":"http://hdl.handle.net/2142/97331","source":{"id":"https://openalex.org/S4306401358","display_name":"Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801919071","host_organization_name":"University of Illinois System","host_organization_lineage":["https://openalex.org/I2801919071"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"mag:2774466565","doi":null,"is_oa":false,"landing_page_url":"https://www.ideals.illinois.edu/bitstream/2142/97331/1/BOLLAERT-DISSERTATION-2017.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:www.ideals.illinois.edu:2142/97331","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2142/97331","pdf_url":"http://hdl.handle.net/2142/97331","source":{"id":"https://openalex.org/S4306401358","display_name":"Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801919071","host_organization_name":"University of Illinois System","host_organization_lineage":["https://openalex.org/I2801919071"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2774466565.pdf","grobid_xml":"https://content.openalex.org/works/W2774466565.grobid-xml"},"referenced_works_count":84,"referenced_works":["https://openalex.org/W44784447","https://openalex.org/W107839595","https://openalex.org/W1527181082","https://openalex.org/W1549690114","https://openalex.org/W1963878196","https://openalex.org/W1964118321","https://openalex.org/W1974704788","https://openalex.org/W1984516218","https://openalex.org/W1984707599","https://openalex.org/W1985129563","https://openalex.org/W1991249712","https://openalex.org/W1992936223","https://openalex.org/W1995404834","https://openalex.org/W1996254614","https://openalex.org/W1996629316","https://openalex.org/W2003189347","https://openalex.org/W2007948644","https://openalex.org/W2008936239","https://openalex.org/W2014127183","https://openalex.org/W2016162827","https://openalex.org/W2016567207","https://openalex.org/W2023388602","https://openalex.org/W2023555055","https://openalex.org/W2041135149","https://openalex.org/W2045255538","https://openalex.org/W2048331974","https://openalex.org/W2049054274","https://openalex.org/W2053836109","https://openalex.org/W2055166970","https://openalex.org/W2056412554","https://openalex.org/W2058429306","https://openalex.org/W2071298586","https://openalex.org/W2074738783","https://openalex.org/W2074935117","https://openalex.org/W2096044210","https://openalex.org/W2096420290","https://openalex.org/W2096657471","https://openalex.org/W2098291431","https://openalex.org/W2099647077","https://openalex.org/W2102567223","https://openalex.org/W2105778736","https://openalex.org/W2108807267","https://openalex.org/W2109978145","https://openalex.org/W2112165124","https://openalex.org/W2114110854","https://openalex.org/W2117469149","https://openalex.org/W2118698089","https://openalex.org/W2119079747","https://openalex.org/W2119958965","https://openalex.org/W2121149730","https://openalex.org/W2122401765","https://openalex.org/W2130632081","https://openalex.org/W2131293625","https://openalex.org/W2132836066","https://openalex.org/W2139113477","https://openalex.org/W2140248886","https://openalex.org/W2142377418","https://openalex.org/W2143397552","https://openalex.org/W2145277893","https://openalex.org/W2148563799","https://openalex.org/W2149100552","https://openalex.org/W2150378783","https://openalex.org/W2152787748","https://openalex.org/W2158156478","https://openalex.org/W2162596555","https://openalex.org/W2168709334","https://openalex.org/W2169482678","https://openalex.org/W2170945203","https://openalex.org/W2183566242","https://openalex.org/W2187477173","https://openalex.org/W2253177041","https://openalex.org/W2286627699","https://openalex.org/W2290390881","https://openalex.org/W2312645628","https://openalex.org/W2316138036","https://openalex.org/W2318174246","https://openalex.org/W2328208048","https://openalex.org/W2336695325","https://openalex.org/W2415438560","https://openalex.org/W2484656186","https://openalex.org/W2538670878","https://openalex.org/W2552638262","https://openalex.org/W2585087946","https://openalex.org/W3010232489"],"related_works":["https://openalex.org/W2774672244","https://openalex.org/W2963117010","https://openalex.org/W2625678039","https://openalex.org/W2924525308","https://openalex.org/W2955891623","https://openalex.org/W2415438560","https://openalex.org/W4303685907","https://openalex.org/W3082124254","https://openalex.org/W2484656186","https://openalex.org/W4407756489"],"abstract_inverted_index":{"Background:":[0],"Older":[1],"adults":[2,118,136,221,250,299,312,345,372,389,456],"with":[3,96,119,155,222,251,284,300,313,330,346,373,390,457],"multiple":[4],"sclerosis":[5],"(MS)":[6],"experience":[7,392],"age-related":[8],"declines":[9,394],"in":[10,31,78,115,137,202,254,296,310,343,364,395,414,454],"physical":[11,32,102,111,148,168,187,230,257,279,288,334,365,399,431],"and":[12,22,33,40,74,98,103,112,126,132,141,150,177,198,232,261,276,302,322,366,375,412,419,428,435,445],"cognitive":[13,34,104,113,163,236,293,339,367,406],"function":[14,35,114,169,188,231,237,289,294,335,340,368,407],"that":[15,100,219,248,274,320,353,383],"may":[16],"be":[17,439],"compounded":[18],"by":[19,166],"the":[20,26,45,55,59,72,93,138,142,162,167,183,186,211,354,449],"disease":[21,41],"its":[23],"progression.":[24],"However,":[25],"extent":[27,143,309],"to":[28,129,144,194,243,267,306,385],"which":[29,145],"impairments":[30],"are":[36],"manifestations":[37],"of":[38,44,58,76,124,173,185,229,235,278,287,324,333,357,398,405,417,422,430,442,451],"MS":[39,77,99,120,223,252,301,374,391],"progression,":[42],"reflective":[43],"general":[46,139],"aging":[47,97,453],"process,":[48],"or":[49,88],"perhaps":[50],"two":[51],"detrimental":[52],"processes":[53],"exacerbating":[54],"synergistic":[56],"effects":[57],"other":[60],"is":[61,66],"relatively":[62],"unknown.":[63],"Further,":[64,425],"there":[65],"very":[67],"little":[68],"known":[69],"about":[70],"managing":[71],"progression":[73],"consequences":[75],"older":[79,117,135,220,249,298,311,344,371,388,455],"adults.":[80],"Physical":[81],"activity":[82,149,258,280],"participation":[83],"might":[84],"provide":[85],"a":[86,203,207,285,307,331,440],"protective":[87],"potentially":[89],"restorative":[90],"effect":[91],"on":[92,226],"mechanisms":[94],"associated":[95,154,283,329],"influence":[101],"function.":[105],"Objectives:":[106],"The":[107,171,379],"present":[108,380],"study":[109],"examined":[110],"40":[116,130],"(i.e.,":[121,238,408],"60":[122],"years":[123],"age":[125],"older)":[127],"compared":[128,242,266,384],"age-":[131],"sex-matched":[133],"healthy":[134,244,268,303,376,386,452],"population":[140],"objectively":[146],"measured":[147],"sedentary":[151,263,325,423,436],"behavior":[152,264,326,437],"were":[153,179,191,281,327],"these":[156],"functions.":[157],"Methods:":[158],"Participants":[159,190],"initially":[160],"underwent":[161],"assessments,":[164],"followed":[165],"assessments.":[170,189],"order":[172],"tests":[174],"was":[175],"standardized":[176],"participants":[178],"provided":[180],"seated-rest":[181],"between":[182,370],"administrations":[184],"then":[192],"instructed":[193],"wear":[195,200],"an":[196],"accelerometer":[197],"document":[199],"time":[201],"log":[204],"book":[205],"for":[206,362,448],"seven-day":[208],"period":[209],"after":[210],"testing":[212],"session.":[213],"Results:":[214],"Independent":[215],"samples":[216],"t-tests":[217],"indicated":[218,247],"performed":[224],"worse":[225],"all":[227,396],"measures":[228],"one":[233,403],"measure":[234],"information":[239,409],"processing":[240,410],"speed)":[241],"controls.":[245,269,377],"ANCOVAs":[246],"engaged":[253],"less":[255],"moderate-to-vigorous":[256],"(MVPA)":[259],"(minutes/day)":[260,265,359],"more":[262],"Partial":[270,315],"Pearson":[271,316],"correlations":[272,317],"demonstrated":[273,319,352],"levels":[275,321,356,416,421,427],"patterns":[277,323,429],"significantly":[282,328],"majority":[286,332],"variables":[290,295,336,341,369],"but":[291,305,337,401],"not":[292,338],"both":[297,426],"controls":[304],"greater":[308],"MS.":[314,347,458],"further":[318,351],"primarily":[342],"Linear":[348],"regression":[349],"analyses":[350],"low":[355],"MVPA":[358,418],"partially":[360],"accounted":[361],"differences":[363],"Conclusions:":[378],"results":[381],"indicate":[382],"controls,":[387],"large":[393],"areas":[397],"function,":[400],"only":[402],"area":[404],"speed),":[411],"engage":[413],"lower":[415],"higher":[420],"behavior.":[424],"activity,":[432],"namely":[433],"MVPA,":[434],"should":[438],"focus":[441],"clinical":[443],"rehabilitation":[444],"behavioral":[446],"interventions":[447],"promotion":[450]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2017-12-22T00:00:00"}
