{"id":"https://openalex.org/W2773044408","doi":"https://doi.org/10.1080/13543784.2018.1416091","title":"Investigational PD-1 inhibitors in HL and NHL and biomarkers for predictors of response and outcome","display_name":"Investigational PD-1 inhibitors in HL and NHL and biomarkers for predictors of response and outcome","publication_year":2017,"publication_date":"2017-12-12","ids":{"openalex":"https://openalex.org/W2773044408","doi":"https://doi.org/10.1080/13543784.2018.1416091","mag":"2773044408","pmid":"https://pubmed.ncbi.nlm.nih.gov/29228840","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5762391"},"language":"en","primary_location":{"id":"doi:10.1080/13543784.2018.1416091","doi":"https://doi.org/10.1080/13543784.2018.1416091","is_oa":false,"landing_page_url":"https://doi.org/10.1080/13543784.2018.1416091","pdf_url":null,"source":{"id":"https://openalex.org/S131064935","display_name":"Expert Opinion on Investigational Drugs","issn_l":"1354-3784","issn":["1354-3784","1744-7658"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert Opinion on Investigational Drugs","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC5762391","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004461141","display_name":"Andr\u00e9s Chang","orcid":"https://orcid.org/0000-0001-6679-9060","observed_orcids":["https://orcid.org/0000-0001-6679-9060"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4390039307","display_name":"Winship Cancer Institute","ror":"https://ror.org/02gars961","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I132943300","https://openalex.org/I150468666","https://openalex.org/I4390039307"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andres Chang","raw_affiliation_strings":["Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA","Emory Vaccine Center, Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4390039307"]},{"raw_affiliation_string":"Emory Vaccine Center, Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058050578","display_name":"Danielle Schlafer","orcid":"https://orcid.org/0000-0003-1792-7841","observed_orcids":["https://orcid.org/0000-0003-1792-7841"]},"institutions":[{"id":"https://openalex.org/I132943300","display_name":"Emory Healthcare","ror":"https://ror.org/00yksxf10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I132943300","https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Danielle Schlafer","raw_affiliation_strings":["Department of Pharmaceutical Services, Emory Healthcare, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Services, Emory Healthcare, Atlanta, GA, USA","institution_ids":["https://openalex.org/I132943300"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082892912","display_name":"Christopher R. Flowers","orcid":"https://orcid.org/0000-0002-9524-3990","observed_orcids":["https://orcid.org/0000-0002-9524-3990"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4390039307","display_name":"Winship Cancer Institute","ror":"https://ror.org/02gars961","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I132943300","https://openalex.org/I150468666","https://openalex.org/I4390039307"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher R. Flowers","raw_affiliation_strings":["Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4390039307"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017284444","display_name":"Pamela B. Allen","orcid":"https://orcid.org/0000-0002-3959-3662","observed_orcids":["https://orcid.org/0000-0002-3959-3662"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4390039307","display_name":"Winship Cancer Institute","ror":"https://ror.org/02gars961","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I132943300","https://openalex.org/I150468666","https://openalex.org/I4390039307"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Pamela B. Allen","raw_affiliation_strings":["Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4390039307"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5017284444"],"corresponding_institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4390039307"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.02686236,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"27","issue":"1","first_page":"55","last_page":"70"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.018200000748038292,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pd-1-inhibitors","display_name":"PD-1 inhibitors","score":0.9959999918937683},{"id":"https://openalex.org/keywords/pd-1-pd-l1-pathway","display_name":"PD-1/PD-L1 pathway","score":0.9100000262260437},{"id":"https://openalex.org/keywords/hodgkin-lymphoma","display_name":"Hodgkin's disease","score":0.9779999852180481},{"id":"https://openalex.org/keywords/non-hodgkin-lymphoma","display_name":"non-Hodgkin lymphoma","score":1.0},{"id":"https://openalex.org/keywords/immune-evasion","display_name":"immune evasion","score":0.7039999961853027},{"id":"https://openalex.org/keywords/predictive-biomarkers","display_name":"predictive biomarkers","score":0.843999981880188},{"id":"https://openalex.org/keywords/treatment-response-prediction","display_name":"treatment response prediction","score":0.7649999856948853},{"id":"https://openalex.org/keywords/immunotherapy","display_name":"immunotherapy","score":0.734000027179718},{"id":"https://openalex.org/keywords/combination-immunotherapy","display_name":"combination immunotherapy","score":0.6159999966621399},{"id":"https://openalex.org/keywords/cell-therapy","display_name":"cell therapy","score":0.6589999794960022},{"id":"https://openalex.org/keywords/tumor-specific-immunity","display_name":"tumor-specific immunity","score":0.875}],"concepts":[{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6588780879974365},{"id":"https://openalex.org/C3020580240","wikidata":"https://www.wikidata.org/wiki/Q663272","display_name":"Expert opinion","level":2,"score":0.6508611440658569},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5792467594146729},{"id":"https://openalex.org/C2781053074","wikidata":"https://www.wikidata.org/wiki/Q21100639","display_name":"PD-L1","level":4,"score":0.5298247933387756},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.452629029750824},{"id":"https://openalex.org/C2992779791","wikidata":"https://www.wikidata.org/wiki/Q209369","display_name":"Hodgkin lymphoma","level":3,"score":0.44441384077072144},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.4377995729446411},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3987845778465271},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3924843966960907},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.32556411623954773},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.32036787271499634},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1819118857383728},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.14938119053840637}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D006689","descriptor_name":"Hodgkin Disease","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006689","descriptor_name":"Hodgkin Disease","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006689","descriptor_name":"Hodgkin Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008228","descriptor_name":"Lymphoma, Non-Hodgkin","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008228","descriptor_name":"Lymphoma, Non-Hodgkin","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008228","descriptor_name":"Lymphoma, Non-Hodgkin","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015507","descriptor_name":"Drugs, Investigational","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D015507","descriptor_name":"Drugs, Investigational","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D061026","descriptor_name":"Programmed Cell Death 1 Receptor","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D061026","descriptor_name":"Programmed Cell Death 1 Receptor","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1080/13543784.2018.1416091","doi":"https://doi.org/10.1080/13543784.2018.1416091","is_oa":false,"landing_page_url":"https://doi.org/10.1080/13543784.2018.1416091","pdf_url":null,"source":{"id":"https://openalex.org/S131064935","display_name":"Expert Opinion on Investigational Drugs","issn_l":"1354-3784","issn":["1354-3784","1744-7658"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert Opinion on Investigational Drugs","raw_type":"journal-article"},{"id":"pmid:29228840","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29228840","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert opinion on investigational drugs","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:5283313","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5762391","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5762391","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5762391","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Expert Opin Investig Drugs","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:5283313","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5762391","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4399673850","display_name":"Translational Physician-Scientist Training Program in Oncology","funder_award_id":"T32CA160040","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8997950485","display_name":null,"funder_award_id":"4T32CA160040-04","funder_id":"https://openalex.org/F4320333204","funder_display_name":"Winship Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320333204","display_name":"Winship Cancer Institute","ror":"https://ror.org/02gars961"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":157,"referenced_works":["https://openalex.org/W94592798","https://openalex.org/W1135493307","https://openalex.org/W1492161184","https://openalex.org/W1538902372","https://openalex.org/W1566018542","https://openalex.org/W1749548564","https://openalex.org/W1898697707","https://openalex.org/W1910012553","https://openalex.org/W1940241680","https://openalex.org/W1949743561","https://openalex.org/W1964886243","https://openalex.org/W1976133526","https://openalex.org/W1978436252","https://openalex.org/W1981463252","https://openalex.org/W1982488143","https://openalex.org/W1986354050","https://openalex.org/W1992581811","https://openalex.org/W1993686673","https://openalex.org/W2006774237","https://openalex.org/W2011228017","https://openalex.org/W2016983859","https://openalex.org/W2020586896","https://openalex.org/W2027907558","https://openalex.org/W2028376975","https://openalex.org/W2033194905","https://openalex.org/W2034678662","https://openalex.org/W2038070878","https://openalex.org/W2040793402","https://openalex.org/W2047502920","https://openalex.org/W2050115670","https://openalex.org/W2051830227","https://openalex.org/W2052877948","https://openalex.org/W2054119257","https://openalex.org/W2056535502","https://openalex.org/W2060035249","https://openalex.org/W2066002010","https://openalex.org/W2071582678","https://openalex.org/W2072043666","https://openalex.org/W2075736621","https://openalex.org/W2079018735","https://openalex.org/W2079335705","https://openalex.org/W2083025888","https://openalex.org/W2085604821","https://openalex.org/W2089669094","https://openalex.org/W2093463728","https://openalex.org/W2097855813","https://openalex.org/W2098853737","https://openalex.org/W2099747853","https://openalex.org/W2100412095","https://openalex.org/W2103532863","https://openalex.org/W2104347254","https://openalex.org/W2107752337","https://openalex.org/W2108367695","https://openalex.org/W2109485845","https://openalex.org/W2111500154","https://openalex.org/W2112680373","https://openalex.org/W2115091768","https://openalex.org/W2118342755","https://openalex.org/W2118471749","https://openalex.org/W2119146367","https://openalex.org/W2122385884","https://openalex.org/W2124060252","https://openalex.org/W2125616358","https://openalex.org/W2128758225","https://openalex.org/W2131234364","https://openalex.org/W2134345729","https://openalex.org/W2135175382","https://openalex.org/W2136859769","https://openalex.org/W2139461240","https://openalex.org/W2140875987","https://openalex.org/W2143163879","https://openalex.org/W2144256523","https://openalex.org/W2147240268","https://openalex.org/W2149479626","https://openalex.org/W2150492554","https://openalex.org/W2151818828","https://openalex.org/W2152006714","https://openalex.org/W2152897456","https://openalex.org/W2155464214","https://openalex.org/W2156353875","https://openalex.org/W2159170430","https://openalex.org/W2166662937","https://openalex.org/W2171741398","https://openalex.org/W2198093519","https://openalex.org/W2222086386","https://openalex.org/W2222106751","https://openalex.org/W2295409074","https://openalex.org/W2302719382","https://openalex.org/W2309444408","https://openalex.org/W2327153404","https://openalex.org/W2336761956","https://openalex.org/W2337659275","https://openalex.org/W2338463544","https://openalex.org/W2339890238","https://openalex.org/W2340187745","https://openalex.org/W2401455386","https://openalex.org/W2412725897","https://openalex.org/W2417294817","https://openalex.org/W2465860350","https://openalex.org/W2466451466","https://openalex.org/W2473498748","https://openalex.org/W2473759462","https://openalex.org/W2504623699","https://openalex.org/W2505138627","https://openalex.org/W2518731208","https://openalex.org/W2526219494","https://openalex.org/W2527905628","https://openalex.org/W2529484692","https://openalex.org/W2529930251","https://openalex.org/W2530034556","https://openalex.org/W2530695400","https://openalex.org/W2535879323","https://openalex.org/W2547310148","https://openalex.org/W2551337088","https://openalex.org/W2552238988","https://openalex.org/W2557336488","https://openalex.org/W2560367415","https://openalex.org/W2560853463","https://openalex.org/W2570159314","https://openalex.org/W2570618306","https://openalex.org/W2571122473","https://openalex.org/W2572174216","https://openalex.org/W2577999417","https://openalex.org/W2581213001","https://openalex.org/W2581557689","https://openalex.org/W2585709526","https://openalex.org/W2586126825","https://openalex.org/W2586232813","https://openalex.org/W2586276931","https://openalex.org/W2588876159","https://openalex.org/W2588916311","https://openalex.org/W2591946624","https://openalex.org/W2592666036","https://openalex.org/W2593533764","https://openalex.org/W2594496276","https://openalex.org/W2595802803","https://openalex.org/W2596886590","https://openalex.org/W2600581432","https://openalex.org/W2605422333","https://openalex.org/W2605683323","https://openalex.org/W2609289346","https://openalex.org/W2609973112","https://openalex.org/W2611189127","https://openalex.org/W2611767787","https://openalex.org/W2612422239","https://openalex.org/W2618541274","https://openalex.org/W2622805445","https://openalex.org/W2622853459","https://openalex.org/W2626474566","https://openalex.org/W2741922362","https://openalex.org/W2743439797","https://openalex.org/W2752106614","https://openalex.org/W2752355139","https://openalex.org/W2753945613","https://openalex.org/W2765568148","https://openalex.org/W2772084440","https://openalex.org/W2791168547"],"related_works":["https://openalex.org/W2419498501","https://openalex.org/W2520750334","https://openalex.org/W135658021","https://openalex.org/W3014865085","https://openalex.org/W2314461546","https://openalex.org/W3024153056","https://openalex.org/W2758450355","https://openalex.org/W2261608863","https://openalex.org/W4235809212","https://openalex.org/W2902189441"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Inhibitors":[1],"against":[2],"the":[3,8,22,31,37,58,65],"PD-1/PD-L1":[4],"pathway":[5],"are":[6],"revolutionizing":[7],"treatment":[9],"and":[10,44,47],"management":[11],"of":[12,21,24,39,50],"malignancies.":[13],"AREAS":[14],"COVERED:":[15],"We":[16,54],"summarize":[17],"our":[18],"current":[19],"understanding":[20],"function":[23],"PD-1,":[25],"its":[26],"role":[27],"in":[28,42,57,76],"immune":[29,66,101],"evasion,":[30],"clinical":[32],"data":[33],"available":[34],"that":[35,56,63],"support":[36],"use":[38],"PD-1":[40,70,83],"antagonist":[41],"Hodgkin":[43],"non-Hodgkin":[45],"lymphomas,":[46],"potential":[48],"predictors":[49],"response.":[51],"EXPERT":[52],"OPINION:":[53],"anticipate":[55],"next":[59],"10":[60],"years,":[61],"agents":[62],"modulate":[64],"system":[67],"such":[68],"as":[69,93],"antagonists":[71,84],"will":[72,85],"be":[73,86],"increasingly":[74],"used":[75,92],"favor":[77],"over":[78],"traditional":[79],"cytotoxic":[80],"chemotherapeutic":[81],"agents.":[82],"combined":[87],"with":[88],"future":[89],"immunotherapies":[90],"or":[91],"adjuncts":[94],"to":[95,98],"cellular":[96],"therapy":[97],"boost":[99],"tumor-specific":[100],"responses.":[102]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2017-12-22T00:00:00"}
