{"id":"https://openalex.org/W2772829219","doi":"https://doi.org/10.6084/m9.figshare.5121697","title":"Supplementary Material for: Systematic Review of the Epidemiology of Complicated Peptic Ulcer Disease: Incidence, Recurrence, Risk Factors and Mortality","display_name":"Supplementary Material for: Systematic Review of the Epidemiology of Complicated Peptic Ulcer Disease: Incidence, Recurrence, Risk Factors and Mortality","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W2772829219","doi":"https://doi.org/10.6084/m9.figshare.5121697","mag":"2772829219"},"language":"en","primary_location":{"id":"pmh:oai:figshare.com:article/5121697","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Supplementary_Material_for_Systematic_Review_of_the_Epidemiology_of_Complicated_Peptic_Ulcer_Disease_Incidence_Recurrence_Risk_Factors_and_Mortality/5121697","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},"volume":null,"type":"supplementary-materials","is_traditional":false,"indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://figshare.com/articles/dataset/Supplementary_Material_for_Systematic_Review_of_the_Epidemiology_of_Complicated_Peptic_Ulcer_Disease_Incidence_Recurrence_Risk_Factors_and_Mortality/5121697","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053945242","display_name":"Jun Lau","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lau, J.Y.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Sung, J.","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sung, J.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112444296","display_name":"C. Hill","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hill, C.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017114097","display_name":"Catherine Henderson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Henderson, C.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113585241","display_name":"C. W. Howden","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Howden, C.W.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5110014043","display_name":"David C. Metz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Metz, D.C.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.7567999958992004,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.7567999958992004,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11378","display_name":"Gastrointestinal Bleeding Diagnosis and Treatment","score":0.24079999327659607,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11855","display_name":"Gastrointestinal disorders and treatments","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/complicated-peptic-ulcer","display_name":"complicated peptic ulcer","score":0.972000002861023},{"id":"https://openalex.org/keywords/bleeding-peptic-ulcer","display_name":"peptic ulcer bleeding","score":0.9779999852180481},{"id":"https://openalex.org/keywords/perforated-peptic-ulcer","display_name":"peptic ulcer perforation","score":0.9869999885559082},{"id":"https://openalex.org/keywords/ulcer-recurrence","display_name":"ulcer recurrence","score":0.7509999871253967},{"id":"https://openalex.org/keywords/incidence","display_name":"incidence","score":0.7250000238418579},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.8899999856948853},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.9940000176429749},{"id":"https://openalex.org/keywords/nonsteroidal-anti-inflammatory-drugs","display_name":"nonsteroidal anti-inflammatory drugs","score":0.9079999923706055},{"id":"https://openalex.org/keywords/aspirin","display_name":"aspirin","score":0.9620000123977661},{"id":"https://openalex.org/keywords/helicobacter-pylori-infection","display_name":"Helicobacter pylori infection","score":0.9679999947547913},{"id":"https://openalex.org/keywords/proton-pump-inhibitors","display_name":"proton pump inhibitors","score":0.9399999976158142},{"id":"https://openalex.org/keywords/ulcer-size","display_name":"ulcer size","score":0.9190000295639038}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9146184921264648},{"id":"https://openalex.org/C2778456384","wikidata":"https://www.wikidata.org/wiki/Q1508510","display_name":"Perforation","level":3,"score":0.7654993534088135},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.729816198348999},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6484817862510681},{"id":"https://openalex.org/C2776409635","wikidata":"https://www.wikidata.org/wiki/Q180556","display_name":"Helicobacter pylori","level":2,"score":0.6136689186096191},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.6054956316947937},{"id":"https://openalex.org/C2779390736","wikidata":"https://www.wikidata.org/wiki/Q17095243","display_name":"Peptic","level":3,"score":0.567510187625885},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5081634521484375},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4945537745952606},{"id":"https://openalex.org/C2780656511","wikidata":"https://www.wikidata.org/wiki/Q172941","display_name":"Peptic ulcer","level":2,"score":0.4526859521865845},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3821808695793152},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C2778527123","wikidata":"https://www.wikidata.org/wiki/Q11750728","display_name":"Punching","level":2,"score":0.0},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:figshare.com:article/5121697","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Supplementary_Material_for_Systematic_Review_of_the_Epidemiology_of_Complicated_Peptic_Ulcer_Disease_Incidence_Recurrence_Risk_Factors_and_Mortality/5121697","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"doi:10.6084/m9.figshare.5121697","doi":"https://doi.org/10.6084/m9.figshare.5121697","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.5121697","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"},{"id":"doi:10.6084/m9.figshare.5121697.v1","doi":"https://doi.org/10.6084/m9.figshare.5121697.v1","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.5121697.v1","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"}],"best_oa_location":{"id":"pmh:oai:figshare.com:article/5121697","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Supplementary_Material_for_Systematic_Review_of_the_Epidemiology_of_Complicated_Peptic_Ulcer_Disease_Incidence_Recurrence_Risk_Factors_and_Mortality/5121697","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2026639275","https://openalex.org/W2091488670","https://openalex.org/W2793506194","https://openalex.org/W2076221436","https://openalex.org/W4221083558","https://openalex.org/W2598819021","https://openalex.org/W2417630334","https://openalex.org/W4413442296","https://openalex.org/W2091069386","https://openalex.org/W2141910092"],"abstract_inverted_index":{"Background/Aims:":[0],"The":[1,79],"incidence":[2,63],"of":[3,18,25,40,65,83,95,134,183],"uncomplicated":[4],"peptic":[5,26,42,66,105,135,169],"ulcer":[6,27,43,67,106,123,136,170],"has":[7,20],"decreased":[8],"in":[9],"recent":[10],"years.":[11],"It":[12],"is":[13],"unclear":[14],"what":[15],"the":[16,23,35,45,91,132],"impact":[17],"this":[19],"been":[21],"on":[22],"epidemiology":[24],"complications.":[28],"This":[29],"systematic":[30],"review":[31],"aimed":[32],"to":[33],"determine":[34],"incidence,":[36],"recurrence":[37,82,94,110],"and":[38,44,69,73,90,108,122,148,159,186],"mortality":[39,140],"complicated":[41],"risk":[46,133,182],"factors":[47,103],"associated":[48,163],"with":[49,164],"these":[50],"events.":[51],"Methods:":[52],"Systematic":[53],"PubMed":[54],"searches.":[55],"Results:":[56],"Overall,":[57],"93":[58],"studies":[59],"were":[60,71,162],"identified.":[61],"Annual":[62],"estimates":[64],"hemorrhage":[68,84,147],"perforation":[70,96],"19.4\u201357.0":[72],"3.8\u201314":[74],"per":[75],"100,000":[76],"individuals,":[77],"respectively.":[78],"average":[80,92],"7-day":[81],"was":[85,97,141],"13.9%":[86],"(95%":[87,99,143,150],"CI:":[88,100,144,151],"8.4\u201319.4),":[89],"long-term":[93],"12.2%":[98],"2.5\u201321.9).":[101],"Risk":[102],"for":[104],"complications":[107,185],"their":[109],"included":[111],"nonsteroidal":[112],"anti-inflammatory":[113],"drug":[114],"and/or":[115],"acetylsalicylic":[116],"acid":[117],"use,":[118],"Helicobacter":[119],"pylori":[120],"infection":[121],"size":[124],"\u22671":[125],"cm.":[126],"Proton":[127],"pump":[128],"inhibitor":[129],"use":[130],"reduced":[131],"hemorrhage.":[137],"Average":[138],"30-day":[139],"8.6%":[142],"5.8\u201311.4)":[145],"after":[146,153],"23.5%":[149],"15.5\u201331.0)":[152],"perforation.":[154],"Older":[155],"age,":[156],"comorbidity,":[157],"shock":[158],"delayed":[160],"treatment":[161],"increased":[165],"mortality.":[166],"Conclusions:":[167],"Complicated":[168],"remains":[171],"a":[172,180],"substantial":[173],"healthcare":[174],"problem":[175],"which":[176],"places":[177],"patients":[178],"at":[179],"high":[181],"recurrent":[184],"death.":[187]},"counts_by_year":[],"updated_date":"2026-10-17T09:40:24.721904","created_date":"2017-12-22T00:00:00"}