{"id":"https://openalex.org/W2771230199","doi":"https://doi.org/10.18632/aging.101334","title":"Human longevity: 25 genetic loci associated in 389,166 UK biobank participants","display_name":"Human longevity: 25 genetic loci associated in 389,166 UK biobank participants","publication_year":2017,"publication_date":"2017-12-06","ids":{"openalex":"https://openalex.org/W2771230199","doi":"https://doi.org/10.18632/aging.101334","mag":"2771230199","pmid":"https://pubmed.ncbi.nlm.nih.gov/29227965","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5764389"},"language":"en","primary_location":{"id":"doi:10.18632/aging.101334","doi":"https://doi.org/10.18632/aging.101334","is_oa":false,"landing_page_url":"https://doi.org/10.18632/aging.101334","pdf_url":null,"source":{"id":"https://openalex.org/S4210231119","display_name":"Aging","issn_l":"1945-4589","issn":["1945-4589"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316297","host_organization_name":"Impact Journals LLC","host_organization_lineage":["https://openalex.org/P4310316297"],"host_organization_lineage_names":["Impact Journals LLC"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5764389","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057577585","display_name":"Luke C. Pilling","orcid":"https://orcid.org/0000-0002-3332-8454","observed_orcids":["https://orcid.org/0000-0002-3332-8454"]},"institutions":[{"id":"https://openalex.org/I23923803","display_name":"University of Exeter","ror":"https://ror.org/03yghzc09","country_code":"GB","type":"education","lineage":["https://openalex.org/I23923803"]},{"id":"https://openalex.org/I2801242002","display_name":"Royal Devon and Exeter Hospital","ror":"https://ror.org/03jrh3t05","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801242002"]},{"id":"https://openalex.org/I4210154447","display_name":"Exeter Hospital","ror":"https://ror.org/05a5dkj17","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210109172","https://openalex.org/I4210154447"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Luke C. Pilling","raw_affiliation_strings":["Epidemiology and Public Health Group, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Exeter, EX2 5DW, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epidemiology and Public Health Group, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Exeter, EX2 5DW, UK","institution_ids":["https://openalex.org/I23923803","https://openalex.org/I2801242002","https://openalex.org/I4210154447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086396866","display_name":"Chia\u2010Ling Kuo","orcid":"https://orcid.org/0000-0003-4452-2380","observed_orcids":["https://orcid.org/0000-0003-4452-2380"]},"institutions":[{"id":"https://openalex.org/I75929689","display_name":"UConn Health","ror":"https://ror.org/02kzs4y22","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I75929689"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chia-Ling Kuo","raw_affiliation_strings":["Department of Community Medicine and Health Care, Connecticut Institute for Clinical and Translational Science, Institute for Systems Genomics, University of Connecticut Health Center, CT 06269, USA","Institute for Systems Genomics, University of Connecticut Health Center, CT 06269 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Community Medicine and Health Care, Connecticut Institute for Clinical and Translational Science, Institute for Systems Genomics, University of Connecticut Health Center, CT 06269, USA","institution_ids":["https://openalex.org/I75929689"]},{"raw_affiliation_string":"Institute for Systems Genomics, University of Connecticut Health Center, CT 06269 USA","institution_ids":["https://openalex.org/I75929689"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083692349","display_name":"Kamil Sicinski","orcid":"https://orcid.org/0009-0000-4603-8248","observed_orcids":["https://orcid.org/0009-0000-4603-8248"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kamil Sicinski","raw_affiliation_strings":["Center for Demography of Health and Aging, University of Wisconsin, Madison, WI 53706, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Demography of Health and Aging, University of Wisconsin, Madison, WI 53706, USA","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044772300","display_name":"Jone Tamosauskaite","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I23923803","display_name":"University of Exeter","ror":"https://ror.org/03yghzc09","country_code":"GB","type":"education","lineage":["https://openalex.org/I23923803"]},{"id":"https://openalex.org/I2801242002","display_name":"Royal Devon and Exeter Hospital","ror":"https://ror.org/03jrh3t05","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801242002"]},{"id":"https://openalex.org/I4210154447","display_name":"Exeter Hospital","ror":"https://ror.org/05a5dkj17","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210109172","https://openalex.org/I4210154447"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jone Tamosauskaite","raw_affiliation_strings":["Epidemiology and Public Health Group, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Exeter, EX2 5DW, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epidemiology and Public Health Group, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Exeter, EX2 5DW, UK","institution_ids":["https://openalex.org/I23923803","https://openalex.org/I2801242002","https://openalex.org/I4210154447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056759771","display_name":"George A. Kuchel","orcid":"https://orcid.org/0000-0001-8387-7040","observed_orcids":["https://orcid.org/0000-0001-8387-7040"]},"institutions":[{"id":"https://openalex.org/I140172145","display_name":"University of Connecticut","ror":"https://ror.org/02der9h97","country_code":"US","type":"education","lineage":["https://openalex.org/I140172145"]},{"id":"https://openalex.org/I75929689","display_name":"UConn Health","ror":"https://ror.org/02kzs4y22","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I75929689"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"George A. Kuchel","raw_affiliation_strings":["UConn Center on Aging, University of Connecticut, Farmington, CT 06030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UConn Center on Aging, University of Connecticut, Farmington, CT 06030, USA","institution_ids":["https://openalex.org/I140172145","https://openalex.org/I75929689"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032349484","display_name":"Lorna W. Harries","orcid":"https://orcid.org/0000-0001-7791-8061","observed_orcids":["https://orcid.org/0000-0001-7791-8061"]},"institutions":[{"id":"https://openalex.org/I23923803","display_name":"University of Exeter","ror":"https://ror.org/03yghzc09","country_code":"GB","type":"education","lineage":["https://openalex.org/I23923803"]},{"id":"https://openalex.org/I2801242002","display_name":"Royal Devon and Exeter Hospital","ror":"https://ror.org/03jrh3t05","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801242002"]},{"id":"https://openalex.org/I4210154447","display_name":"Exeter Hospital","ror":"https://ror.org/05a5dkj17","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210109172","https://openalex.org/I4210154447"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Lorna W. Harries","raw_affiliation_strings":["Institute of Biomedical and Clinical Sciences, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Exeter, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedical and Clinical Sciences, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Exeter, UK","institution_ids":["https://openalex.org/I23923803","https://openalex.org/I2801242002","https://openalex.org/I4210154447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052285777","display_name":"Pamela Herd","orcid":"https://orcid.org/0000-0002-0137-5846","observed_orcids":["https://orcid.org/0000-0002-0137-5846"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pamela Herd","raw_affiliation_strings":["La Follette School of Public Affairs and the Department of Sociology, University of Wisconsin, Madison, WI 53706, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"La Follette School of Public Affairs and the Department of Sociology, University of Wisconsin, Madison, WI 53706, USA","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052944794","display_name":"Robert B. Wallace","orcid":"https://orcid.org/0000-0001-6040-3803","observed_orcids":["https://orcid.org/0000-0001-6040-3803","https://orcid.org/0000-0003-2038-7145"]},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Wallace","raw_affiliation_strings":["College of Public Health, University of Iowa, Iowa City, IA 52242, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Public Health, University of Iowa, Iowa City, IA 52242, USA","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048196698","display_name":"Luigi Ferrucci","orcid":"https://orcid.org/0000-0002-6273-1613","observed_orcids":["https://orcid.org/0000-0002-6273-1613"]},"institutions":[{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Luigi Ferrucci","raw_affiliation_strings":["National Institute on Aging, Baltimore, MD 21224, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute on Aging, Baltimore, MD 21224, USA","institution_ids":["https://openalex.org/I4210136897"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5001674485","display_name":"David R. Melzer","orcid":"https://orcid.org/0000-0002-0170-3838","observed_orcids":["https://orcid.org/0000-0002-0170-3838"]},"institutions":[{"id":"https://openalex.org/I140172145","display_name":"University of Connecticut","ror":"https://ror.org/02der9h97","country_code":"US","type":"education","lineage":["https://openalex.org/I140172145"]},{"id":"https://openalex.org/I23923803","display_name":"University of Exeter","ror":"https://ror.org/03yghzc09","country_code":"GB","type":"education","lineage":["https://openalex.org/I23923803"]},{"id":"https://openalex.org/I2801242002","display_name":"Royal Devon and Exeter Hospital","ror":"https://ror.org/03jrh3t05","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801242002"]},{"id":"https://openalex.org/I4210154447","display_name":"Exeter Hospital","ror":"https://ror.org/05a5dkj17","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210109172","https://openalex.org/I4210154447"]},{"id":"https://openalex.org/I75929689","display_name":"UConn Health","ror":"https://ror.org/02kzs4y22","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I75929689"]}],"countries":["GB","US"],"is_corresponding":true,"raw_author_name":"David Melzer","raw_affiliation_strings":["Epidemiology and Public Health Group, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Exeter, EX2 5DW, UK","UConn Center on Aging, University of Connecticut, Farmington, CT 06030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epidemiology and Public Health Group, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Exeter, EX2 5DW, UK","institution_ids":["https://openalex.org/I23923803","https://openalex.org/I2801242002","https://openalex.org/I4210154447"]},{"raw_affiliation_string":"UConn Center on Aging, University of Connecticut, Farmington, CT 06030, USA","institution_ids":["https://openalex.org/I140172145","https://openalex.org/I75929689"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5001674485"],"corresponding_institution_ids":["https://openalex.org/I140172145","https://openalex.org/I23923803","https://openalex.org/I2801242002","https://openalex.org/I4210154447","https://openalex.org/I75929689"],"apc_list":null,"apc_paid":null,"fwci":12.6487,"has_fulltext":false,"cited_by_count":210,"citation_normalized_percentile":{"value":0.99301752,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"9","issue":"12","first_page":"2504","last_page":"2520"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9609000086784363,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9609000086784363,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10676","display_name":"Genetics, Aging, and Longevity in Model Organisms","score":0.02759999968111515,"subfield":{"id":"https://openalex.org/subfields/1302","display_name":"Aging"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13354","display_name":"Genetics and Physical Performance","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/human-longevity","display_name":"human longevity","score":0.9959999918937683},{"id":"https://openalex.org/keywords/genetic-loci","display_name":"genetic loci","score":0.8849999904632568},{"id":"https://openalex.org/keywords/polygenic-risk","display_name":"polygenic risk","score":0.7059999704360962},{"id":"https://openalex.org/keywords/cellular-senescence","display_name":"cellular senescence","score":0.9819999933242798},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.9959999918937683},{"id":"https://openalex.org/keywords/lipid-metabolism","display_name":"lipid metabolism","score":1.0},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.9309999942779541},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.8769999742507935}],"concepts":[{"id":"https://openalex.org/C116567970","wikidata":"https://www.wikidata.org/wiki/Q864217","display_name":"Biobank","level":2,"score":0.907902181148529},{"id":"https://openalex.org/C2776759703","wikidata":"https://www.wikidata.org/wiki/Q1066907","display_name":"Longevity","level":2,"score":0.8728014230728149},{"id":"https://openalex.org/C2779403534","wikidata":"https://www.wikidata.org/wiki/Q2944360","display_name":"Centenarian","level":3,"score":0.7982150316238403},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.678662896156311},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5149791836738586},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5068281292915344},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.4131365418434143},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.371826708316803},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3048872947692871},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.24084347486495972},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2384852170944214},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.12335118651390076},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09113115072250366},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006113","descriptor_name":"United Kingdom","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008136","descriptor_name":"Longevity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010290","descriptor_name":"Parents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018070","descriptor_name":"Biological Specimen Banks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020412","descriptor_name":"Multifactorial Inheritance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.18632/aging.101334","doi":"https://doi.org/10.18632/aging.101334","is_oa":false,"landing_page_url":"https://doi.org/10.18632/aging.101334","pdf_url":null,"source":{"id":"https://openalex.org/S4210231119","display_name":"Aging","issn_l":"1945-4589","issn":["1945-4589"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316297","host_organization_name":"Impact Journals LLC","host_organization_lineage":["https://openalex.org/P4310316297"],"host_organization_lineage_names":["Impact Journals LLC"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4676848","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5764389","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5764389","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5764389","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging (Albany NY)","raw_type":"Text"},{"id":"pmid:29227965","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29227965","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging","raw_type":"Journal Article"},{"id":"pmh:oai:figshare.com:article/29747630","doi":null,"is_oa":false,"landing_page_url":"https://figshare.com/articles/journal_contribution/Human_longevity_25_genetic_loci_associated_in_389_166_UK_biobank_participants/29747630","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:ore.exeter.ac.uk:10871/34358","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10871/34358","pdf_url":null,"source":{"id":"https://openalex.org/S4306401998","display_name":"Open Research Exeter (University of Exeter)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I23923803","host_organization_name":"University of Exeter","host_organization_lineage":["https://openalex.org/I23923803"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:4676848","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5764389","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G11730674","display_name":"Aging Together: Brothers and Sisters of the Wisconsin Longitudinal Study","funder_award_id":"R01AG033285","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G4020298327","display_name":"GENETIC AND ENVIRONMENTAL INFLUENCES ON AGEING WELL IN THE UK BIOBANK","funder_award_id":"MR/M023095/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G6167584732","display_name":"The Wisconsin Longitudinal Study:  Tracking the Life Course","funder_award_id":"5p01ag021079-08","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6376995420","display_name":null,"funder_award_id":"P01-AG021079","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G6559503508","display_name":"The Wisconsin Longitudinal Study: As We Age","funder_award_id":"R01AG009775","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G9000887882","display_name":"Health and Retirement Study: Yrs 35-40","funder_award_id":"U01AG009740","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G9000907083","display_name":"Center for Demography of Health and Aging","funder_award_id":"P30AG017266","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W1588920275","https://openalex.org/W1723491975","https://openalex.org/W1966775465","https://openalex.org/W1967703805","https://openalex.org/W2000833392","https://openalex.org/W2002715948","https://openalex.org/W2009285220","https://openalex.org/W2026353898","https://openalex.org/W2027663660","https://openalex.org/W2028832354","https://openalex.org/W2039153962","https://openalex.org/W2058484936","https://openalex.org/W2063535842","https://openalex.org/W2069519394","https://openalex.org/W2078657844","https://openalex.org/W2092653359","https://openalex.org/W2096939566","https://openalex.org/W2101605059","https://openalex.org/W2116868464","https://openalex.org/W2121772485","https://openalex.org/W2139852278","https://openalex.org/W2149583210","https://openalex.org/W2153118028","https://openalex.org/W2159914115","https://openalex.org/W2161633633","https://openalex.org/W2168300179","https://openalex.org/W2171241286","https://openalex.org/W2201499402","https://openalex.org/W2206270307","https://openalex.org/W2238851414","https://openalex.org/W2310542696","https://openalex.org/W2317777064","https://openalex.org/W2346626662","https://openalex.org/W2384506977","https://openalex.org/W2411709723","https://openalex.org/W2518402343","https://openalex.org/W2550031966","https://openalex.org/W2560048039","https://openalex.org/W2581423053","https://openalex.org/W2723723801","https://openalex.org/W2737435306","https://openalex.org/W2740078953","https://openalex.org/W2750901335","https://openalex.org/W2770092353"],"related_works":["https://openalex.org/W2384506977","https://openalex.org/W2029744217","https://openalex.org/W2890672865","https://openalex.org/W3135868936","https://openalex.org/W2888023620","https://openalex.org/W2952981231","https://openalex.org/W2752268560","https://openalex.org/W2955748386","https://openalex.org/W2740078953","https://openalex.org/W2171481698"],"abstract_inverted_index":{"=1,181)":[0],"in":[1,20],"UK":[2],"Biobank.":[3],"The":[4],"results":[5],"suggest":[6],"that":[7],"human":[8],"longevity":[9],"is":[10],"highly":[11],"polygenic":[12],"with":[13],"prominent":[14],"roles":[15],"for":[16],"loci":[17],"likely":[18],"involved":[19],"cellular":[21],"senescence":[22],"and":[23,28],"inflammation,":[24],"plus":[25],"lipid":[26],"metabolism":[27],"cardiovascular":[29],"conditions.":[30],"There":[31],"may":[32],"also":[33],"be":[34],"gender":[35],"specific":[36],"routes":[37],"to":[38],"longevity.":[39]},"counts_by_year":[{"year":2026,"cited_by_count":17},{"year":2025,"cited_by_count":29},{"year":2024,"cited_by_count":25},{"year":2023,"cited_by_count":19},{"year":2022,"cited_by_count":28},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":35},{"year":2019,"cited_by_count":27},{"year":2018,"cited_by_count":15}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2017-12-22T00:00:00"}