{"id":"https://openalex.org/W2770191332","doi":"https://doi.org/10.1093/jxb/erx377","title":"Natural genetic variation and hybridization in plants","display_name":"Natural genetic variation and hybridization in plants","publication_year":2017,"publication_date":"2017-09-01","ids":{"openalex":"https://openalex.org/W2770191332","doi":"https://doi.org/10.1093/jxb/erx377","mag":"2770191332","pmid":"https://pubmed.ncbi.nlm.nih.gov/29161427","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5853786"},"language":"en","primary_location":{"id":"doi:10.1093/jxb/erx377","doi":"https://doi.org/10.1093/jxb/erx377","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jxb/erx377","pdf_url":null,"source":{"id":"https://openalex.org/S32610980","display_name":"Journal of Experimental Botany","issn_l":"0022-0957","issn":["0022-0957","1460-2431"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Experimental Botany","raw_type":"journal-article"},"volume":null,"type":"editorial","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1093/jxb/erx377","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036043656","display_name":"Ian R. Henderson","orcid":"https://orcid.org/0000-0001-5066-1489","observed_orcids":["https://orcid.org/0000-0001-5066-1489"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Ian R Henderson","raw_affiliation_strings":["Department of Plant Sciences, Downing Street, University of Cambridge, Cambridge, CB2 3EA, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Plant Sciences, Downing Street, University of Cambridge, Cambridge, CB2 3EA, United Kingdom","institution_ids":["https://openalex.org/I241749"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044903153","display_name":"David E. Salt","orcid":"https://orcid.org/0000-0003-0283-0991","observed_orcids":["https://orcid.org/0000-0003-0283-0991"]},"institutions":[{"id":"https://openalex.org/I142263535","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58","country_code":"GB","type":"education","lineage":["https://openalex.org/I142263535"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"David E Salt","raw_affiliation_strings":["Division of Plant and Crop Sciences, School of Biosciences, University of Nottingham, Sutton Bonington Campus, Sutton Bonington, LE12 5RD, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Plant and Crop Sciences, School of Biosciences, University of Nottingham, Sutton Bonington Campus, Sutton Bonington, LE12 5RD, United Kingdom","institution_ids":["https://openalex.org/I142263535"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5036043656","https://openalex.org/A5044903153"],"corresponding_institution_ids":["https://openalex.org/I142263535","https://openalex.org/I241749"],"apc_list":{"value":3292,"currency":"GBP","value_usd":4341},"apc_paid":{"value":3292,"currency":"GBP","value_usd":4341},"fwci":null,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"68","issue":"20","first_page":"5415","last_page":"5417"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.8202999830245972,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.8202999830245972,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.06199999898672104,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":0.01730000041425228,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/natural-genetic-variation","display_name":"natural genetic variation","score":0.9580000042915344},{"id":"https://openalex.org/keywords/plant-hybridization","display_name":"plant hybridization","score":0.8610000014305115},{"id":"https://openalex.org/keywords/crop-domestication","display_name":"crop domestication","score":0.7720000147819519},{"id":"https://openalex.org/keywords/arabidopsis-thaliana","display_name":"Arabidopsis thaliana","score":0.8840000033378601},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.7739999890327454},{"id":"https://openalex.org/keywords/latitudinal-variation","display_name":"latitudinal variation","score":0.746999979019165},{"id":"https://openalex.org/keywords/transposable-elements","display_name":"transposable elements","score":0.593999981880188},{"id":"https://openalex.org/keywords/wheat","display_name":"wheat","score":0.3529999852180481},{"id":"https://openalex.org/keywords/hexaploid-genome","display_name":"hexaploid genome","score":0.7300000190734863},{"id":"https://openalex.org/keywords/climate-change-adaptation","display_name":"climate change adaptation","score":0.6740000247955322},{"id":"https://openalex.org/keywords/crop-breeding","display_name":"crop breeding","score":0.6069999933242798},{"id":"https://openalex.org/keywords/crop-wild-relatives","display_name":"crop wild relatives","score":0.531000018119812},{"id":"https://openalex.org/keywords/genetic-diversity","display_name":"genetic diversity","score":0.4309999942779541},{"id":"https://openalex.org/keywords/genotype-phenotype-correlation","display_name":"genotype-phenotype correlation","score":0.5820000171661377}],"concepts":[{"id":"https://openalex.org/C2778334786","wikidata":"https://www.wikidata.org/wiki/Q1586270","display_name":"Variation (astronomy)","level":2,"score":0.6107885837554932},{"id":"https://openalex.org/C68873052","wikidata":"https://www.wikidata.org/wiki/Q349856","display_name":"Genetic variation","level":3,"score":0.5845569968223572},{"id":"https://openalex.org/C2776608160","wikidata":"https://www.wikidata.org/wiki/Q4785462","display_name":"Natural (archaeology)","level":2,"score":0.5451057553291321},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5130316019058228},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.3861965537071228},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.34586137533187866},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.26085370779037476},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1479400396347046},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0721498429775238},{"id":"https://openalex.org/C44870925","wikidata":"https://www.wikidata.org/wiki/Q37547","display_name":"Astrophysics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000069600","descriptor_name":"Plant Breeding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000073336","descriptor_name":"Whole Genome Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004843","descriptor_name":"Epistasis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006824","descriptor_name":"Hybridization, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010944","descriptor_name":"Plants","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018556","descriptor_name":"Crops, Agricultural","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018745","descriptor_name":"Genome, Plant","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D040641","descriptor_name":"Quantitative Trait Loci","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/jxb/erx377","doi":"https://doi.org/10.1093/jxb/erx377","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jxb/erx377","pdf_url":null,"source":{"id":"https://openalex.org/S32610980","display_name":"Journal of Experimental Botany","issn_l":"0022-0957","issn":["0022-0957","1460-2431"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Experimental Botany","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5011082","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5853786","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5853786","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5853786","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Exp Bot","raw_type":"Text"},{"id":"pmid:29161427","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29161427","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of experimental botany","raw_type":"Editorial"}],"best_oa_location":{"id":"doi:10.1093/jxb/erx377","doi":"https://doi.org/10.1093/jxb/erx377","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jxb/erx377","pdf_url":null,"source":{"id":"https://openalex.org/S32610980","display_name":"Journal of Experimental Botany","issn_l":"0022-0957","issn":["0022-0957","1460-2431"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Experimental Botany","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9208999872207642,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3306153304","display_name":null,"funder_award_id":"BB/L000113/2","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1876047377","https://openalex.org/W1990813498","https://openalex.org/W2010032067","https://openalex.org/W2014814201","https://openalex.org/W2050768722","https://openalex.org/W2123430325","https://openalex.org/W2158845372","https://openalex.org/W2313992076","https://openalex.org/W2409013835","https://openalex.org/W2419574648","https://openalex.org/W2462490406","https://openalex.org/W2737928538","https://openalex.org/W2743518148","https://openalex.org/W2753238678","https://openalex.org/W2767109002","https://openalex.org/W2951822269","https://openalex.org/W2952522917","https://openalex.org/W6654115536","https://openalex.org/W6888003625","https://openalex.org/W6992981392","https://openalex.org/W7019357850"],"related_works":["https://openalex.org/W1592133829","https://openalex.org/W7098417258","https://openalex.org/W4407730720","https://openalex.org/W1757110396","https://openalex.org/W2150168968","https://openalex.org/W1987864324","https://openalex.org/W2046256455","https://openalex.org/W4214480852","https://openalex.org/W2101984926","https://openalex.org/W2108104709"],"abstract_inverted_index":{"Extensive":[0,301],"genetic":[1,24,54,71,130,192,359,520,614,628,648,656,930,1086,1111,1194,1232],"variation":[2,25,55,84,258,360,521,636,657,742,948,1087,1114,1139,1195,1208,1233],"underpinning":[3],"phenotypic":[4,544,596,618],"traits":[5,547,674],"exists":[6,27],"in":[7,28,46,63,73,87,117,170,196,229,254,259,330,409,418,503,525,617,638,675,695,743,774,887,937,1000,1010,1046,1115,1127,1149,1156,1196,1209,1217],"natural":[8,53,83,129,519,947,1014,1197,1231],"plant":[9,52,145,199,420,821,1138,1238],"populations,":[10],"and":[11,32,160,172,178,193,239,313,415,441,457,473,485,506,551,585,601,613,641,677,701,715,738,770,783,802,807,823,831,841,867,994,1006,1035,1040,1088,1112,1119,1125,1143,1166,1219,1234],"this":[12,217,230],"is":[13,104,137,152,445,666,811,860,877,903,1117,1146],"intimately":[14],"connected":[15,843],"to":[16,65,143,148,157,166,236,316,327,337,481,513,522,533,562,634,653,670,759,838,844,889,905,933,1012,1121,1136,1174,1177,1189,1204,1211,1225,1237],"the":[17,29,49,105,167,181,197,224,290,293,320,338,358,362,378,398,410,452,476,495,504,511,543,552,565,609,635,689,724,798,818,853,938,954,986,1021,1052,1202],"process":[18,1024],"of":[19,35,37,51,70,81,93,107,223,227,284,292,357,383,401,439,451,460,478,491,497,528,546,554,556,581,590,608,611,626,647,692,748,785,792,820,855,863,871,891,900,914,972,979,1038,1071,1095,1193,1207,1230,1243],"evolutionary":[20],"adaptation.":[21],"Importantly,":[22,898,984,1085],"such":[23,454,645],"also":[26,1067,1099],"close":[30],"relatives":[31],"progenitor":[33,966],"species":[34,97,295,725,1150],"many":[36,423],"our":[38,1175,1222],"staple":[39],"crops,":[40],"which":[41,796,997,1073],"has":[42,185,244,510,576,682,756],"great":[43,582],"potential":[44,512],"significance":[45],"agriculture.":[47],"Therefore,":[48],"study":[50,862],"can":[56,548,816,836,949,998,1018,1030,1074],"provide":[57,605,1134,1201],"new":[58,431,856,1131],"insights":[59],"into":[60,135,190],"biological":[61],"mechanisms,":[62,788],"addition":[64,888,1011],"providing":[66,364],"a":[67,78,118,138,250,354,365,667,684,729,734,761,812,907,969],"vital":[68],"source":[69],"diversity":[72],"crop":[74,424,659,1128],"breeding.":[75],"Humans":[76],"have":[77,706,776,1043,1098],"long":[79,803],"history":[80,751],"exploiting":[82],"via":[85,111,536,953],"hybridization":[86,825,835],"plants,":[88],"for":[89,280,368,518,687,882,910,1077],"example":[90,103],"during":[91,595,658,985,1081],"domestication":[92,106],"crops":[94,163],"from":[95,216,310,319,348,397,964],"wild":[96],"(Doebley":[98],"et":[99,123,206,210,266,270,463,467,827,848,941,1026,1059,1063,1103,1107],"al.,":[100,124,207,211,267,271,464,468,828,849,942,1027,1060,1104],"2006).":[101],"An":[102],"modern":[108],"bread":[109],"wheat":[110],"two":[112,708,977],"successive":[113],"inter-species":[114],"hybridizations,":[115],"resulting":[116,168],"complex":[119,591,672],"hexaploid":[120],"genome":[121,298,324,482,939,1079],"(Mayer":[122],"2014).":[125],"Today,":[126],"understanding":[127,161,222,1227],"how":[128,144,162,834],"polymorphisms":[131,195,302],"(i.e.":[132],"genotype)":[133],"translate":[134],"phenotype":[136,575],"central":[139],"question,":[140],"with":[141,155,232,257,917,928,1091,1151],"relevance":[142,233],"populations":[146,872],"adapt":[147,165],"changing":[149],"environments.":[150],"This":[151,444,1029,1145,1199],"particularly":[153,446,1147],"relevant":[154],"respect":[156],"climate":[158,1223],"change":[159],"will":[164,219,650,1186,1200,1240],"alterations":[169],"temperature":[171],"water":[173],"availability.":[174],"To":[175],"address":[176],"these":[177,744,864,1180],"related":[179],"questions":[180],"1001":[182,339,411],"Genomes":[183],"Project":[184],"provided":[186],"high":[187,929,1069],"resolution":[188,1216],"insight":[189],"global":[191,1228],"epigenetic":[194,790,1113],"model":[198],"Arabidopsis":[200,285,296,720,754,775],"thaliana":[201,297,307,323,406],"(Arabidopsis)":[202],"(Box":[203],"1;":[204],"Alonso-Blanco":[205],"2016;":[208,465],"Kawakatsu":[209,269],"2016).":[212,272],"The":[213,371,488],"resources":[214],"generated":[215],"project":[218,341],"facilitate":[220],"further":[221,369,951],"molecular":[225,690,787],"basis":[226,691],"adaptation":[228,1213,1239],"species,":[231,363,421,425],"more":[234,274],"broadly":[235],"other":[237,331,419],"plants":[238,639,676,1116],"animals.":[240,678],"For":[241,470,1163],"example,":[242,471,1164],"it":[243,286,758,1185],"emerged":[245,577],"that":[246,289,435,573,631,718,755,815],"DNA":[247,263,432,857,973],"methylation":[248],"shows":[249,373],"clear":[251,288],"latitudinal":[252],"pattern":[253],"Arabidopsis,":[255,696],"associated":[256,916,1090],"trans":[260],"modifiers":[261],"(e.g.":[262],"methyltransferases)":[264],"(Dubin":[265],"2015;":[268],"As":[273,851,1182,1221],"whole-genome":[275],"seque":[276],"nces":[277],"were":[278,325],"completed":[279],"various":[281],"wild-collected":[282],"accessions":[283,407],"became":[287],"concept":[291],"single":[294,970],"was":[299],"problematic.":[300],"exist":[303],"between":[304,568,593,896],"different":[305,311,349,404,571,766],"A.":[306,322,405],"individuals":[308,346],"collected":[309,347],"locations,":[312],"genes":[314,745,779,1048],"thought":[315],"be":[317,328,523,549,560,651,727,842,906,950,1122,1187,1242],"non-functional":[318],"first":[321,987],"found":[326],"functional":[329],"individuals.":[332],"Such":[333,921],"considerations":[334],"gave":[335],"rise":[336],"genomes":[340,412,1097],"(1001genomes.org).":[342],"Sequencing":[343,870],"over":[344,402],"1000":[345,403],"geographic":[350,763],"locations":[351],"would":[352],"allow":[353,436],"fuller":[355],"characterization":[356],"within":[361,377,753],"powerful":[366,668,908],"resource":[367],"investigations.":[370],"image":[372],"an":[374,579,880],"educational":[375],"installation":[376],"Cruickshank":[379],"Botanic":[380],"Gardens":[381],"(University":[382],"Aberdeen)":[384],"focused":[385],"on":[386],"genomics":[387],"called":[388],"\u2018a":[389],"living-plant":[390],"double":[391],"helix\u2019":[392],"created":[393],"by":[394,430,699,794,976,1032,1160],"Liam":[395],"Salt":[396],"diverse":[399,749],"set":[400],"used":[408],"project.":[413],"These":[414,620,704],"similar":[416],"projects":[417],"including":[422,789,1051],"are":[426,459,530,622,923],"being":[427],"greatly":[428],"strengthened":[429],"sequencing":[433,440,483,501,858,1132],"technologies":[434,859,902,1133],"unprecedented":[437,1215],"depths":[438],"longer":[442],"reads.":[443],"valuable":[447],"when":[448],"repetitive":[449,1153],"elements":[450],"genome,":[453],"as":[455,578,624,697,879,926],"transposons":[456],"centromeres,":[458],"interest":[461,529,557],"(Quadrana":[462],"Stuart":[466],"2016;).":[469],"Legget":[472],"Clark":[474],"review":[475,1008],"application":[477,899],"nanopore":[479,492],"technology":[480,493,1183],"(Legget":[484,866],"Clark,":[486,868],"2017).":[487,643,740,772,809,829,850,869,943,1028,1065],"compact":[489],"size":[490],"opens":[494],"possibility":[496],"performing":[498],"hitherto":[499],"challenging":[500],"experiments":[502],"field,":[505],"its":[507,1235],"low":[508],"cost":[509],"accelerate":[514],"genomics.":[515],"In":[516],"order":[517],"utilized":[524],"agriculture,":[526],"backgrounds":[527],"typically":[531,924],"crossed":[532],"domesticated":[534],"strains,":[535],"either":[537,728],"intra-":[538],"or":[539,733,1155],"inter-specific":[540],"hybridization.":[541],"However,":[542],"expression":[545],"complex,":[550],"inheritance":[553,629,1094],"characteristics":[555],"may":[558,726],"not":[559],"easy":[561],"predict.":[563],"Hence,":[564],"interaction":[566,649],"observed":[567,637],"genotypes":[569],"at":[570,874,1140,1214],"loci":[572,663,1089],"determine":[574,719,817],"area":[580],"interest.":[583],"Forsberg":[584],"Carlborg":[586],"(2017)":[587],"discuss":[588],"examples":[589,625,890],"interactions":[592],"variants":[594],"expression,":[597],"using":[598,968],"both":[599,1033],"theoretical":[600],"experimental":[602],"observations.":[603],"They":[604],"detailed":[606],"analysis":[607,665],"roles":[610],"epistasis":[612],"variance":[615],"heterogeneity":[616],"expression.":[619],"concepts":[621],"examined":[623],"non-additive":[627],"patterns":[630,646,1206,1229],"probably":[632],"contribute":[633],"(Forsberg":[640],"Carlborg,":[642],"Understanding":[644],"important":[652,1148],"fully":[654,1123],"utilize":[655],"improvement.":[660],"Quantitative":[661],"trait":[662,814],"(QTL)":[664],"approach":[669,686,881,909],"understand":[671],"multigenic":[673],"Indeed,":[679],"QTL":[680],"mapping":[681],"been":[683,1044,1100],"successful":[685,1045],"dissecting":[688],"flowering-time":[693],"control":[694],"reviewed":[698],"Bloomer":[700],"Dean":[702],"(2017).":[703],"approaches":[705,1042],"identified":[707,777,1101],"major":[709],"genes,":[710],"FLOWERING":[711],"LOCUS":[712],"C":[713],"(FLC)":[714],"FRIGIDA":[716],"(FRI),":[717],"life":[721,750],"history;":[722],"hence,":[723],"vernalization-requiring":[730],"winter":[731],"annual":[732],"rapid":[735],"cycler":[736],"(Bloomer":[737,769,806],"Dean,":[739,771,808],"Natural":[741,1110],"underpins":[746],"evolution":[747],"strategies":[752],"allowed":[757],"colonize":[760],"wide":[762],"range,":[764],"spanning":[765],"environmental":[767,1212],"conditions":[768],"Studies":[773],"key":[778,813],"controlling":[780,1049],"flowering":[781],"time":[782],"elucidation":[784],"their":[786],"silencing":[791],"FLC":[793],"vernalization,":[795],"involves":[797],"Polycomb":[799],"repression":[800],"system":[801],"non-coding":[804],"RNAs":[805],"Flowering":[810],"extent":[819],"inter-":[822],"intra-specific":[824],"(Schmickl":[826,847,940],"Yant":[830,1106],"colleagues":[832,1007],"examine":[833,1205],"lead":[837],"allele":[839,919],"introgression":[840],"speciation":[845],"events":[846],"discussed,":[852],"utility":[854],"accelerating":[861],"phenomena":[865],"occurring":[873],"hybrid":[875],"zones":[876],"discussed":[878],"identifying":[883,911,1047],"introgressed":[884],"adaptive":[885,918],"alleles,":[886],"horizontal":[892],"gene":[893,1056],"transfer":[894],"(HGT)":[895],"species.":[897,1129],"deep-sequencing":[901],"proving":[904],"genomic":[912],"islands":[913,922],"divergence":[915,931],"introgression.":[920],"detected":[925],"regions":[927,935,1158],"compared":[932],"non-differentiated":[934],"elsewhere":[936],"Once":[944],"hybrids":[945],"form,":[946],"recombined":[952],"meiotic":[955,988,1022,1093],"cell":[956,989],"division":[957,990],"(Hunter,":[958,982,1003],"2015).":[959,983,1004],"Meiosis":[960],"generates":[961],"haploid":[962],"gametes":[963],"diploid":[965],"cells,":[967],"round":[971],"replication":[974],"followed":[975],"rounds":[978],"chromosome":[980],"segregation":[981],"homologous":[991],"chromosomes":[992],"pair":[993],"undergo":[995],"recombination,":[996,1050],"result":[999],"reciprocal":[1001],"crossover":[1002],"Henderson":[1005],"how,":[1009],"reassorting":[1013],"variation,":[1015,1039],"sequence":[1016,1179],"polymorphism":[1017],"itself":[1019],"modify":[1020],"recombination":[1023],"(Lawrence":[1025,1058],"occur":[1031],"cis-":[1034],"trans-acting":[1036],"effects":[1037],"QTL-mapping":[1041],"conserved":[1053],"E3":[1054],"ligase":[1055],"HEI10":[1057],"2017;":[1061],"Ziolkowski":[1062],"al.":[1064,1108],"Plants":[1066],"show":[1068],"rates":[1070],"polyploidy,":[1072],"create":[1075],"challenges":[1076],"stable":[1078,1092],"transmission":[1080],"meiosis":[1082],"(Otto,":[1083],"2007).":[1084],"polyploid":[1096],"(Griffiths":[1102],"2006;":[1105],"2013).":[1109],"extensive,":[1118],"remains":[1120],"described":[1124],"harnessed":[1126],"Nevertheless,":[1130],"opportunities":[1135],"explore":[1137],"greater":[1141],"depth":[1142],"accuracy.":[1144],"large,":[1152],"genomes,":[1154],"chromosomal":[1157],"typified":[1159],"repeated":[1161],"sequences.":[1162],"centromeres":[1165],"ribosomal":[1167],"RNA":[1168],"clusters":[1169],"remain":[1170],"poorly":[1171],"understood":[1172],"due":[1173],"inability":[1176],"completely":[1178],"regions.":[1181],"advances":[1184],"possible":[1188],"obtain":[1190],"near-complete":[1191],"descriptions":[1192],"populations.":[1198],"opportunity":[1203],"relation":[1210],"space":[1218],"time.":[1220],"continues":[1224],"change,":[1226],"relationship":[1236],"thus":[1241],"critical":[1244],"importance.":[1245]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-12-04T00:00:00"}